-
1
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntingdon's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993;72:971-83.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
2
-
-
0029997090
-
Phenotypic characterisation of individuals with 30-40 CAG repeats in the Huntington's disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats
-
Rubinsztein DC, Leggo J, Coles R, et al. Phenotypic characterisation of individuals with 30-40 CAG repeats in the Huntington's disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats. Am J Hum Genet 1996;58:16-22.
-
(1996)
Am J Hum Genet
, vol.58
, pp. 16-22
-
-
Rubinsztein, D.C.1
Leggo, J.2
Coles, R.3
-
4
-
-
0027261537
-
Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease
-
Snell RG, MacMillan JC, Cheadle JP, et al. Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease. Nat Genet 1993;4:393-7.
-
(1993)
Nat Genet
, vol.4
, pp. 393-397
-
-
Snell, R.G.1
MacMillan, J.C.2
Cheadle, J.P.3
-
5
-
-
0027240431
-
Trinucleotide repeat length instability and age of onset in Huntington's disease
-
Duyao M, Ambrose C, Myers R, et al. Trinucleotide repeat length instability and age of onset in Huntington's disease. Nat Genet 1993;4:387-92.
-
(1993)
Nat Genet
, vol.4
, pp. 387-392
-
-
Duyao, M.1
Ambrose, C.2
Myers, R.3
-
6
-
-
0027176364
-
The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease
-
Andrew SE, Goldberg VP, Kremer B, et al. The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease. Nat Genet 1993;4:398-403.
-
(1993)
Nat Genet
, vol.4
, pp. 398-403
-
-
Andrew, S.E.1
Goldberg, V.P.2
Kremer, B.3
-
7
-
-
0027361698
-
The normal Huntington disease (HD) allele or a closely associated linked gene influences age at onset of HD
-
Fairer LA, Cupples LA, Wiater P, Conneally PM, Gusella JF, Myers RH. The normal Huntington disease (HD) allele or a closely associated linked gene influences age at onset of HD. Am J Hum Genet 1993;53:125-30.
-
(1993)
Am J Hum Genet
, vol.53
, pp. 125-130
-
-
Fairer, L.A.1
Cupples, L.A.2
Wiater, P.3
Conneally, P.M.4
Gusella, J.F.5
Myers, R.H.6
-
8
-
-
0028073822
-
Late-onset Huntington's disease: A clinical and molecular study
-
James CM, Houlihan GD, Snell RG, Cheadle JP, Harper PS. Late-onset Huntington's disease: a clinical and molecular study. Age Ageing 1994;23:445-8.
-
(1994)
Age Ageing
, vol.23
, pp. 445-448
-
-
James, C.M.1
Houlihan, G.D.2
Snell, R.G.3
Cheadle, J.P.4
Harper, P.S.5
-
9
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D. Apolipoprotein E: high-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993;90:1977-81.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
-
10
-
-
0028872558
-
Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: Implications for the pathogenesis and treatment of Alzheimer's disease
-
Evans KG, Berger EP, Cho CG, Weisgraber KH, Lansbury PT. Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer's disease. Proc Natl Acad Sci USA 1995;92:763-7.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 763-767
-
-
Evans, K.G.1
Berger, E.P.2
Cho, C.G.3
Weisgraber, K.H.4
Lansbury, P.T.5
-
11
-
-
0028173205
-
Amyloid- associated proteins α1-antichymotrypsin and apolipoprotein E assembly of Alzheimer β-protein into filaments
-
Ma J, Yee A, Brewer HB, Das S, Potter H. Amyloid- associated proteins α1-antichymotrypsin and apolipoprotein E assembly of Alzheimer β-protein into filaments. Nature 1996;372:92-4.
-
(1996)
Nature
, vol.372
, pp. 92-94
-
-
Ma, J.1
Yee, A.2
Brewer, H.B.3
Das, S.4
Potter, H.5
-
12
-
-
0030025431
-
Association of apolipoprotein E σ4 allele with bulbar-onset motor neuron disease
-
Al-Chaalabi A, Enayat ZE, Bakker MC, et al. Association of apolipoprotein E σ4 allele with bulbar-onset motor neuron disease. Lancet 1996;347:159-60.
-
(1996)
Lancet
, vol.347
, pp. 159-160
-
-
Al-Chaalabi, A.1
Enayat, Z.E.2
Bakker, M.C.3
-
13
-
-
0029765553
-
Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and β-amyloid peptides
-
Miyata M, Smith JD. Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and β-amyloid peptides. Nat Genet 1996;14:55-61.
-
(1996)
Nat Genet
, vol.14
, pp. 55-61
-
-
Miyata, M.1
Smith, J.D.2
-
14
-
-
0027194791
-
Gene dose of apolipoprotein-E type-4 allele and the risk of Alzheimer's disease in late-onset families
-
Corder EH, Saunders AM, Strittmater WJ, et al Gene dose of apolipoprotein-E type-4 allele and the risk of Alzheimer's disease in late-onset families. Science 1993;261: 921-3.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmater, W.J.3
-
15
-
-
0029036661
-
Apolipoprotein E genotype in diverse neurodegenerative0 disorders
-
Schneider JA, Gearing M, Robbins RS, de l'Aune W, Mirra SS. Apolipoprotein E genotype in diverse neurodegenerative0 disorders. Ann Neurol 1995;38:131-5.
-
(1995)
Ann Neurol
, vol.38
, pp. 131-135
-
-
Schneider, J.A.1
Gearing, M.2
Robbins, R.S.3
De l'Aune, W.4
Mirra, S.S.5
-
16
-
-
0025801744
-
Apolipoprotein E genotyping by one-stage PCR
-
Wenham PR, Price WH, Blundell G. Apolipoprotein E genotyping by one-stage PCR. Lancet 1991;337:1158-9.
-
(1991)
Lancet
, vol.337
, pp. 1158-1159
-
-
Wenham, P.R.1
Price, W.H.2
Blundell, G.3
-
18
-
-
0026006874
-
Covariate dependent age of onset distributions for Huntington's disease
-
Krawczak M, Bockel B, Sandkuijl L, Thies U, Fenton I, Harper PS. Covariate dependent age of onset distributions for Huntington's disease. Am J Hum Genet 1991;49:735-45.
-
(1991)
Am J Hum Genet
, vol.49
, pp. 735-745
-
-
Krawczak, M.1
Bockel, B.2
Sandkuijl, L.3
Thies, U.4
Fenton, I.5
Harper, P.S.6
-
19
-
-
24444469071
-
The clinical and molecular spectrum of spinocerebellar ataxia 3 and Machado-Joseph disease
-
Stevanin, G, Cancel G, Didierjean O, et al. The clinical and molecular spectrum of spinocerebellar ataxia 3 and Machado-Joseph disease. Eur J Hum Genet 1996;4S1:120.
-
(1996)
Eur J Hum Genet
, vol.4 S1
, pp. 120
-
-
Stevanin, G.1
Cancel, G.2
Didierjean, O.3
-
20
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L, Sathasivam K, Seller M, et al. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 1996;87:493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
-
21
-
-
0029791355
-
Huntington disease: New insights into the relationship between CAG expansion and disease
-
Nasir J, Goldberg YP, Hayden MR. Huntington disease: new insights into the relationship between CAG expansion and disease. Hum Mol Genet 1996;5:1431-5.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1431-1435
-
-
Nasir, J.1
Goldberg, Y.P.2
Hayden, M.R.3
-
22
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
Davies SW, Turmaine M, Cozens BA, et al. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell 1997;90:537-48.
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
-
23
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DiFiglia M, Sapp E, Chase KO, et al. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 1997;277:1990-3.
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.O.3
-
24
-
-
0028803757
-
A huntingtin-associated protein enriched in brain with implications for pathology
-
Li XJ, Li SH, Sharp AH, et al. A huntingtin-associated protein enriched in brain with implications for pathology. Nature 1995;378:398-402.
-
(1995)
Nature
, vol.378
, pp. 398-402
-
-
Li, X.J.1
Li, S.H.2
Sharp, A.H.3
-
25
-
-
0029664992
-
Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH
-
Burke JR, Enghild JJ, Martin ME, et al Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. Nat Med 1996;2:347-50.
-
(1996)
Nat Med
, vol.2
, pp. 347-350
-
-
Burke, J.R.1
Enghild, J.J.2
Martin, M.E.3
-
26
-
-
0028986690
-
Apolipoprotein E e4 allele is associated with deposition of amyloid β-protein following head injury
-
Nicholl JAR, Roberts GW, Graham DI. Apolipoprotein E e4 allele is associated with deposition of amyloid β-protein following head injury. Nat Med 1995;2:135-7.
-
(1995)
Nat Med
, vol.2
, pp. 135-137
-
-
Nicholl, J.A.R.1
Roberts, G.W.2
Graham, D.I.3
-
27
-
-
0029926462
-
Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease: A possible clue to the higher incidence of Alzheimer disease in women
-
Payami H, Zareparsi S, Montee KR, et al. Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease: a possible clue to the higher incidence of Alzheimer disease in women. Am J Hum Genet 1996;58:803-11.
-
(1996)
Am J Hum Genet
, vol.58
, pp. 803-811
-
-
Payami, H.1
Zareparsi, S.2
Montee, K.R.3
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