Angiotensin II and nitric oxide: A question of balance

Regulatory Peptides

Volumn 81, Issue 1-3, 1999, Pages 1-10

  Millatt, Lesley J ^a   Abdel Rahman, Emaad M ^a   Siragy, Helmy M ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Adrenal; Angiotensin II; Cardiovascular system; Central nervous system; Kidney; Nitric oxide

Indexed keywords

1 (4 AMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDROIMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN RECEPTOR; ARGININE; LOSARTAN; N METHYL DEXTRO ASPARTIC ACID; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; QUINAPRIL; TEMOCAPRIL; VALSARTAN;

ADRENAL GLAND; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; GENE EXPRESSION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; KIDNEY; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; SIGNAL TRANSDUCTION;

ADRENAL GLANDS; ANGIOTENSIN II; ANIMALS; APOPTOSIS; CENTRAL NERVOUS SYSTEM; HUMANS; KIDNEY; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, ANGIOTENSIN; RENIN-ANGIOTENSIN SYSTEM; SIGNAL TRANSDUCTION;

EID: 0033031531     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(99)00027-0     Document Type: Review

References (83)

1. Clauser E., Curnow K.M., Davies E., Conchon S., Teutsch B., Vianello B., Monnot C., Corvol P. Angiotensin II receptors: protein and gene structures, expression and potential pathological involvements. Eur. J. Endocrinol. 134:1996;403-411.
2. Mukoyama M., Nakajima M., Horiuchi M., Sasamura H., Pratt R.E., Dzau V.J. Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors. J. Biol. Chem. 268:1993;24539-24542.
3. Kambayashi Y., Bardhan S., Takahashi K., Tsuzuki S., Inui H., Hamakubo T., Inagami T. Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition. J. Biol. Chem. 268:1993;24543-24546.
4. Stoll M., Steckelings U.M., Paul M., Bottari S.P., Metzgei R., Unger T. The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells. J. Clin. Invest. 95:1995;651-657.
5. Nio Y., Matsubara H., Murasawa S., Kanasaki M., Inada M. Regulation of gene transcription of angiotensin II receptor subtypes in myocardial infarction. J. Clin. Invest. 95:1995;46-54.
6. Viswanathan M., Saavedra J.M. Expression of angiotensin II AT2 receptors in the rat skin during experimental wound healing. Peptides. 13:1992;783-786.
7. Yamada T., Horiuchi M., Dzau V.J. Angiotensin II type 2 receptor mediates programmed cell death. Proc. Natl. Acad. Sci. USA. 93:1996;156-160.
8. Siragy H.M., Carey R.M. The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats. J. Clin. Invest. 100:1997;264-269.
9. Schelman W.R., Kurth J.L., Berdeaux R.L., Norby S.W., Weyhenmeyer J.A. Angiotensin II type-2 (AT2) receptor-mediated inhibition of NMDA receptor signalling in neuronal cells. Mol. Brain Res. 48:1997;197-205.
10. Michel T., Feron O. Nitric oxide synthases: which, where, how, and why? J. Clin. Invest. 100:1997;2146-2152.
11. Zarahn E.D., Ye X., Ades A.M., Reagan L.P., Fluharty S.J. Angiotensin-induced cyclic GMP production is mediated by multiple receptor subtypes and nitric oxide in N1E-115 neuroblastoma cells. J. Neurochem. 58:1992;1960-1963.
12. McLay J.S., Chatterjee P.K., Mistry S.K., Weerakody R.F., Jardine A.G., McKay N.G., Hawksworth G.M. Atrial natriuretic factor and angiotensin II stimulate nitric oxide release from human proximal tubular cells. Clin. Sci. 89:1995;527-531.
13. Zhang C., Mayeux P.R. Angiotensin II signaling activates the NO-cGMP pathway in rat proximal tubules. Life Sci. 63:1998;L75-L80.
14. Pueyo M.E., Arnal J.F., Rami J., Michel J.B. Angiotensin II stimulates the production of NO and peroxynitrite in endothelial cells. Am. J. Physiol. 274:1998;C214-C220.
15. Seyedi N., Xu X., Nasjletti A., Hintze T.H. Coronary kinin generation mediates nitric oxide release after angiotensin receptor stimulation. Hypertension. 26:1995;164-170.
16. Deng X., Welch W.J., Wilcox C.S. Role of nitric oxide in short-term and prolonged effects of angiotensin II on renal hemodynamics. Hypertension. 27:1996;1173-1179.
17. Zou A.P., Wu F., Cowley A.W.J. Protective effect of angiotensin II-induced increase in nitric oxide in the renal medullary circulation. Hypertension. 31:1998;271-276.
18. Cahill P.A., Redmond E.M., Foster C., Sitzmann J.V. Nitric oxide regulates angiotensin II receptors in vascular smooth muscle cells. Eur. J. Pharmacol. 288:1995;219-229.
19. Ichiki T., Usui M., Kato M., Funakoshi Y., Ito K., Egashira K., Takeshita A. Downregulation of angiotensin II type I receptor gene transcription by nitric oxide. Hypertension. 31:1998;342-348.
20. Usui M., Ichiki T., Katoh M., Egashira K., Takeshita A. Regulation of angiotensin II receptor expression by nitric oxide in rat adrenal gland. Hypertension. 32:1998;527-533.
21. Katoh M., Egashira K., Usui M., Ichiki T., Tomita H., Shimokawa H., Rakugi H., Takeshita A. Cardiac angiotensin II receptors are upregulated by long-term inhibition of nitric oxide synthesis in rats. Circ. Res. 83:1998;743-751.
22. Nakayama I., Kawahara Y., Tsuda T., Okuda M., Yokoyama M. Angiotensin II inhibits cytokine-stimulated inducible nitric oxide synthase expression in vascular smooth muscle cells. J. Biol. Chem. 269:1994;11628-11633.
23. Ikeda U., Maeda Y., Kawahara Y., Yokoyama M., Shimada K. Angiotensin II augments cytokine-stimulated nitric oxide synthesis in rat cardiac myocytes. Circulation. 92:1995;2683-2689.
24. Chandler U., Kopnisky K., Richards E., Crews F.T., Sumners C. Angiotensin II decreases inducible nitric oxide synthase expression in rat astroglial cultures. Am. J. Physiol. 268:1995;C700-C707.
25. Monton M., Lopez-Farre A., Mosquera J.R., Sanchez de Miguel L., Garcia-Duran M., Sierra M.P., Bellver T., Rico L., Casado S. Endogenous angiotensin II produced by endothelium regulates interleukin-1β-stimulated nitric oxide generation in rat isolated vessels. Hypertension. 30:1997;1191-1197.
26. Wolf G., Ziyadeh F.N., Schroeder R., Stahl R.A.K. Angiotensin II inhibits inducible nitric oxide synthase in tubular MCT cells by a posttranscriptional mechanism. J. Am. Soc. Nephrol. 8:1997;551-557.
27. Tojo A., Madsen K.M., Wilcox C.S. Expression of immunoreactive nitric oxide synthase isoforms in rat kidney. Effects of dietary salt and losartan. Jpn. Heart J. 36:1995;389-398.
28. Murakami K., Tsuchiya K., Naruse M., Naruse K., Demura H., Arai J., Nihei H. Nitric oxide synthase I immunoreactivity in the macula densa of the kidney is angiotensin II dependent. Kidney Int. Suppl. 33:1997;S208-S210.
29. Schricker K., Potzl B., Hamann M., Kurtz A. Coordinate changes of renin and brain-type nitric-oxide-synthase (b-NOS) mRNA levels in rat kidneys. Pflugers Arch. 432:1996;394-400.
30. Mattson D.L., Higgins D.J. Influence of dietary sodium intake on renal medullary nitric oxide synthase. Hypertension. 27:1996;688-692.
31. Olson S.C., Dowds T.A., Pino P.A., Barry M.T., Burke-Wolin T. ANG II stimulates endothelial nitric oxide synthase expression in bovine pulmonary artery endothelium. Am. J. Physiol. 273:1997;L315-L321.
32. Hennington B.S., Zhang H., Miller M.T., Granger J.P., Reckelhoff J.F. Angiotensin II stimulates synthesis of endothelial nitric oxide synthase. Hypertension. 31:1998;283-288.
33. Hassid A., Arabshahi H., Bourcier T., Dhaunsi G.S., Matthews C. Nitric oxide selectively amplifies FGF-2-induced mitogenesis in primary rat aortic smooth muscle cells. Am. J. Physiol. 267:1994;H1040-H1048.
34. Baylis C., Mitruka B., Deng A. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J. Clin. Invest. 90:1992;278-281.
35. Ribeiro M.O., Antunes E., de Nucci G., Lovisolo S.M., Zatz R. Chronic inhibition of nitric oxide synthesis. A new model of arterial hypertension. Hypertension. 20:1992;298-303.
36. Arnal J.F., el Amrani A., Chatellier G., Menard J., Michel J.B. Cardiac weight in hypertension induced by nitric oxide synthase blockade. Hypertension. 22:1993;380-387.
37. Michel J.B., Xu Y., Blot S., Philippe M., Chatellier G. Improved survival in rats administered NG-nitro L-arginine methyl ester due to converting enzyme inhibition. J. Cardiovasc. Pharmacol. 28:1996;142-148.
38. Takemoto M., Egashira K., Usui M., Numaguchi K., Toriita H., Tsutsui H., Shimokawa H., Sueishi K., Takeshita A. Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats. J. Clin. Invest. 99:1997;278-287.
39. Luvara G., Pueyo M.E., Philippe M., Mandet C., Savoie F., Henrion D., Michel J.B. Chronic blockade of NO synthase activity induces a proinflammatory phenotype in the arterial wall: prevention by angiotensin II antagonism. Arterioscler. Thromb. Vasc. Biol. 18:1998;1408-1416.
40. Ackermann A., Fernandez-Alfonso M.S., Sanchez de Rojas R., Ortega T., Paul M., Gonzalez C. Modulation of angiotensin-converting enzyme by nitric oxide. Br. J. Pharmacol. 124:1998;291-298.
41. Fernandez-Alfonso M.S., Martorana P.A., Licka I., van Even P., Trobisch D., Scholkens B.A., Paul M. Early induction of angiotensin I-converting enzyme in rat carotid artery after balloon injury. Hypertension. 30:1997;272-277.
42. Kajstura J., Cigola E., Malhotra A., Li P., Cheng W., Meggs L.G., Anversa P. Angiotensin II induces apoptosis of adult ventricular myocytes in vitro. J. Mol. Cell Cardiol. 29:1997;859-870.
43. Cigola E., Kajstura J., Li B., Meggs L.G., Anversa P. Angiotensin II activates programmed myocyte cell death in vitro. Exp. Cell Res. 231:1997;363-371.
44. Yamada T., Akishita M., Pollman M.J., Gibbons G.H., Dzau V.J., Horiuchi M. Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis and antagonizes angiotensin II type I receptor action: an in vitro gene transfer study. Life Sci. 63:1998;L289-L295.
45. Li W., Ye Y., Fu B., Wang J., Yu L., Ichiki T., Inagami T., Ichikawa I., Chen X. Genetic deletion of AT2 receptor antagonizes angiotensin II-induced apoptosis in fibroblasts of the mouse embryo. Biochem. Biophys. Res. Commun. 250:1998;72-76.
46. Pierzchalski P., Reiss K., Cheng W., Cirielli C., Kajstura J., Nitahara J.A., Rizk M., Capogrossi M.C., Anversa P. p53 induce myocyte apoptosis via the activation of the renin-angiotensin system. Exp. Cell Res. 234:1997;57-65.
47. Len A., Claudio P.P., Li Q., Wang X., Reiss K., Wang S., Malhotra A., Kajstura J., Anversa P. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J. Clin. Invest. 101:1998;1326-1342.
48. Shen Y.H., Wang X.L., Wilcken D.E. Nitric oxide induces and inhibits apoptosis through different pathways. FEBS Lett. 433:1998;125-131.
49. Pollman M.J., Yamada T., Horiuchi M., Gibbons G.H. Vasoactive substances regulate vascular smooth muscle cell apoptosis. Countervailing influences of nitric oxide and angiotensin II. Circ. Res. 79:1996;748-756.
50. Dimmeler S., Rippmann V., Weiland U., Haendeler J., Zeiher A.M. Angiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide. Circ. Res. 81:1997;970-976.
51. Navar L.G., Imig J.D., Zou L., Wang C.T. Intrarenal production of angiotensin II. Semin. Nephrol. 17:1997;412-422.
52. Sexton P.M., Zhuo J., Mendelsohn F.A. Localization and regulation of renal receptors for angiotensin II and atrial natriuretic peptide. Tohoku J. Exp. Med. 166:1992;41-56.
53. Kakinuma Y., Fogo A., Inagami T., Ichikawa I. Intrarenal localization of angiotensin II type 1 receptor mRNA in the rat. Kidney Int. 43:1993;1229-1235.
54. Mendelsohn F.A., Millan M., Quirion R., Aguilera G., Chou S.T., Catt K.J. Localization of angiotensin II receptors in rat and monkey kidney by in vitro autoradiography. Kidney Int. Suppl. 20:1987;540-554.
55. Ozono R., Wang Z.Q., Moore A.F., Inagami T., Siragy H.M., Carey R.M. Expression of the subtype 2 angiotensin (AT2) receptor protein in rat kidney. Hypertension. 30:1997;1238-1246.
56. Grone H.J., Simon M., Fuchs E. Autoradiographic characterization of angiotensin receptor subtypes in fetal and adult human kidney. Am. J. Physiol. 262:1992;F326-F331.
57. Goldfarb D.A., Diz D.I., Tubbs R.R., Ferrario C.M., Novick A.C. Angiotensin II receptor subtypes in the human renal cortex and renal cell carcinoma. J. Urol. 151:1994;208-213.
58. Matsubara H., Inada M. Molecular insights into angiotensin II type 1 and type 2 receptors: expression, signaling and physiological function and clinical application of its antagonists. Endocr. J. 45:1998;137-150.
59. Kone B.C., Baylis C. Biosynthesis and homeostatic roles of nitric oxide in the normal kidney. Am. J. Physiol. 272:1997;F561-F578.
60. Kone B.C. Nitric oxide in renal health and disease. Am. J. Kidney Dis. 30:1997;311-333.
61. Star R.A. Intrarenal localization of nitric oxide synthase isoforms and soluble guanylyl cyclase. Clin. Exp. Pharmacol. Physiol. 24:1991;607-610.
62. Mundel P., Bachmann S., Bader M., Fischer A., Kummer W., Mayer B., Kriz W. Expression of nitric oxide synthase in kidney macula densa cells. Kidney Int. 42:1992;1017-1019.
63. Kurtz A., Wagner C. Role of nitric oxide in the control of renin secretion. Am. J. Physiol. 275:1998;F849-F862.
64. Blantz R.C., Gabbai F.B. Effect of angiotensin II on glomerular hemodynamics and ultrafiltration coefficient. Kidney Int. Suppl. 20:1987;S108-S111.
65. Granger J.P., Alberola A.M., Salazar F.J., Nakamura T. Control of renal hemodynamics during intrarenal and systemic blockade of nitric oxide synthesis in conscious dogs. J. Cardiovasc. Pharmacol. 20:(Suppl 12):1992;S160-S162.
66. De Nicola L., Blantz R.C., Gabbai F.B. Nitric oxide and angiotensin II. Glomerular and tubular interaction in the rat. J. Clin. Invest. 89:1992;1248-1256.
67. Ito S., Arima S., Ren Y.L., Juncos L.A., Carretero O.A. Endothelium-derived relaxing factor/nitric oxide modulates angiotensin II action in the isolated microperfused rabbit afferent but not efferent arteriole. J. Clin. Invest. 91:1993;2012-2019.
68. Navar L.G., Carmines P.K., Huang W.C., Mitchell K.D. The tubular effects of angiotensin II. Kidney Int. Suppl. 20:1987;581-588.
69. Majid D.S., Navar L.G. Nitric oxide in the mediation of pressure natriuresis. Clin. Exp. Pharmacol. Physiol. 24:1997;595-599.
70. Dijkhorst-Oei L.T., Koomans H.A. Effects of a nitric oxide synthesis inhibitor on renal sodium handling and diluting capacity in humans. Nephrol. Dial. Transplant. 13:1998;587-593.
71. Braam B., Koomans H.A. Nitric oxide antagonizes the actions of angiotensin II to enhance tubuloglomerular feedback responsiveness. Kidney Int. 48:1995;1406-1411.
72. Mulrow P.J. Renin-angiotensin system in the adrenal. Horm. Metab. Res. 30:1998;346-349.
73. Breslow M.J., Tobin J.R., Bredt D.S., Ferris C.D., Snyder S.H., Traystman R.J. Nitric oxide as a regulator of adrenal blood flow. Am. J. Physiol. 264:1993;H464-H469.
74. Natarajan R., Lanting L., Bai W., Bravo E.L., Nadler J. The role of nitric oxide in the regulation of aldosterone synthesis by adrenal glomerulosa cells. J. Steroid Biochem. Mol. Biol. 61:1997;47-53.
75. Ward L.E., Hunter L.W., Grabau C.E., Tyce G.M., Rorie O.K. Nitric oxide reduces basal efflux of catecholamines from perfused dog adrenal glands. J. Auton. Nerv. Syst. 61:1996;235-242.
76. Simmons J.C., Freeman R.H. L-arginine analogues inhibit aldosterone secretion in rats. Am. J. Physiol. 268:1995;R1137-R1142.
77. Nakayama T., Izumi Y., Soma M., Kanmatsuse K. A nitric oxide synthesis inhibitor prevents the ACTH-stimulated production of aldosterone in rat adrenal gland. Endocr. J. 43:1996;157-162.
78. Hanke C.J., Drewett J.G., Myers C.R., Campbell W.B. Nitric oxide inhibits aldosterone synthesis by a guanylyl cyclase-independent effect. Endocrinology. 139:1998;4053-4060.
79. Del Punta K., Charreau E.H., Pignataro O.P. Nitric oxide inhibits Leydig cell steroidogenesis. Endocrinology. 137:1996;5337-5343.
80. Lenkei Z., Corvol P., Llorens-Cortes C. The angiotensin receptor subtype ATIA predominates in rat forebrain areas involved in blood pressure, body fluid homeostasis and neuroendocrine control. Mol. Brain Res. 30:1995;53-60.
81. Huang Z., Huang P.L., Ma J., Meng W., Ayata C., Fishman M.C., Moskowitz M.A. Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J. Cereb. Blood Flow Metab. 16:1996;981-987.
82. Calapai G., Caputi A.P. Nitric oxide and drinking behaviour. Regul. Pept. 66:1996;117-121.
83. Zhu B., Herbert J. Angiotensin II interacts with nitric oxide-cyclic GMP pathway in the central control of drinking behaviour: mapping with c-fos and NADPH-diaphorase. Neuroscience. 79:1997;543-553.