Thrombopoietin and hematopoietic stem cell development

Annals of the New York Academy of Sciences

Volumn 872, Issue , 1999, Pages 314-319

  Kaushansky, Kenneth ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; GROWTH FACTOR; INTERLEUKIN 3; RECOMBINANT HORMONE; STEEL FACTOR; THROMBOPOIETIN;

ANIMAL CELL; ANIMAL EXPERIMENT; CELL CULTURE; CELL LINEAGE; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; COLONY FORMING CELL; CONFERENCE PAPER; CONTROLLED STUDY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; MEGAKARYOCYTE; MOLECULAR CLONING; MOUSE; NONHUMAN; STEM CELL; THROMBOCYTOPOIESIS;

ANIMALIA;

EID: 0033027161     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb08475.x     Document Type: Conference Paper

References (38)

1. KELEMEN, E., I. CSERHATI & B. TANOS, 1958. Demonstration and some properties of human thrombopoietin in thrombocythemic sera. Acta Haematol. (Basel) 20: 350-355.
2. YAMAMOTO, S. 1957. Mechanism of the development of thrombocytosis due to bleeding. Acta Haematol. (Japan) 20: 163-165.
3. MCDONALD, T.P. 1988. Thrombopoietin: its biology, purification, and characterization. Exp. Hematol. 16: 201-205.
4. HILL, R.J. & J. LEVIN. 1989. Regulators of thrombopoiesis: their biochemistry and physiology. Blood Cells 15: 141-166.
5. DE SAUVAGE, F.J., P.E. HASS, S.D. SPENCER et al. 1994. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature 369: 533-538.
6. LOK, S., K. KAUSHANSKY, R.D. HOLLY et al. 1994. Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 369: 565-568.
7. BARTLEY, T.D., J. BOGENBERGER, P. HUNT et al. 1994. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell 77: 1117-1124.
8. SOHMA, Y., H. AKAHORI, N. SEKI et al. 1994. Molecular cloning and chromosomal localization of the human thrombopoietin gene. FEBS Lett. 353: 57-61.
9. KAUSHANSKY, K. 1995. Thrombopoietin: the primary regulator of platelet production. Blood 86: 419-431.
10. WENDLING, F., P. VARLET, M. CHARON et al. 1986. A retrovirus complex inducing an acute myeloproliferalive leukemia disorder in mice. Virology 149: 242-246.
11. VIGON, I., J.-P. MORNON, L. COCAULT et al. 1992. Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily. Proc. Natl. Acad. Sci. USA 89: 5640-5644.
12. WITTE, O.N. 1990. Steel locus defines new multipotent growth factor. Cell 63: 5-6.
13. BROUDY, V.C. 1997. Stem cell factor and hematopoiesis. Blood 90: 1345-1364.
14. BODINE, D.M., N.E. SEIDEL, K.M. ZSEBO & D. ORLIC. 1993. In vivo administration of stem cell factor to mice increases the absolute number of pluripotent stem cells. Blood 82: 445-455.
15. LI, C.L. & G.R. JOHNSON. 1994. Stem cell factor enhances the survival but not the self-renewal of murine hematopoietic long-term repopulating cells. Blood 84: 408-414.
16. LYMAN, S.D. & S.E.W. JACOBSEN. 1998. c-Kit ligand and flt-3 ligand: stem/progenitor cell factors with overlapping yet distinct activity. Blood 91: 1101-1134.
17. DU, X. & D.A. WILLIAMS. 1997. Interleukin-11: review of molecular, cell biology and clinical use. Blood 89: 3897-3908.
18. YONEMURA, Y., H. KU, S.D. LYMAN & M. OGAWA. 1997. In vitro expansion of hematopoietic progenitors and maintenance of stem cells: comparison between flt3/flk2 ligand and kit ligand. Blood 89: 1915-1921.
19. NANDURKAR, H.H., L. ROBB, D. TARLINTON et al. 1997. Adult mice with targeted mutation of the interleukin-11 receptor (IL11Ra) display normal hematopoiesis. Blood 90: 2148-2159.
20. MILLER, C.L. & C.J. EAVES. 1997. Expansion in vitro of adult murine hematopoietic stem cells with transplantable lympho-myeloid reconstituting ability. Proc. Natl. Acad. Sci. USA 94: 13648-13653.
21. MACKAREHTSCHIAN, K., J.D. HARDIN, K. A. MOORE et al. 1995. Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 3: 147-161.
22. SOUYRI, M., I. VIGON, J.-F. PENCIOLELLI et al. 1990. A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors. Cell 63: 1137-1147.
23. ZEIGLER, F.C., F. DE SAUVAGE, H.R. WIDMER et al. 1994. In vitro megakaryocytopoietic and thrombopoietic activity of c-mpl ligand (TPO) on purified murine hematopoietic stem cells. Blood 84: 4045-4052.
24. KAUSHANSKY, K., N. LIN, A. GROSSMANN et al. 1996. Thrombopoietin expands erythroid, granulocyte-macrophage and megakaryocytic progenitor cells in normal and myelosuppressed mice. Exp. Hematol. 23: 265-269.
25. FARESE, A.M., P. HUNT, L.B. GRAB & T.J. MACVITTIE. 1996. Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multi-lineage hematopoietic reconstitution in nonhuman primates after radiation induced marrow aplasia. J. Clin. Invest. 97: 2145-2151.
26. ALEXANDER, W.S., A.W. ROBERTS, N.A. NICOLA et al. 1996. Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietin receptor c-Mpl. Blood 87: 2162-2170.
27. CARVER-MOORE, K., H.E. BROXMEYER, S.M. LUOH et al. 1996. Low levels of erythroid and myeloid progenitors in thrombopoietin and mpl-deficient mice. Blood 88: 803-808.
28. KU, H., Y. YONEMURA, K. KAUSHANSKY & M. OGAWA. 1996. Thrombopoietin, the ligand for the Mpl receptor, synergizes with steel factor and other early-acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice. Blood 87: 4544-4551.
29. SITNICKA, E., N. LIN, G.V. PRIESTLEY et al. 1996. The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells. Blood 87: 4998-5005.
30. KIMURA, S., A.W. ROBERTS, D. METCALF & W.S. ALEXANDER. 1998. Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin. Proc. Natl. Acad. Sci. USA 95: 1195-1200.
31. SOLAR, G.P., W.G. KERR, F.C. ZEIGLER et al. 1998. Role of c-Mpl in early hematopoiesis. Blood 92: 4-10.
32. KAUSHANSKY, K., V.C. BROUDY, A. GROSSMANN et al. 1995. Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy. J. Clin. Invest. 96: 1683-1687.
33. NEELIS, K.J., L. QINGLIANG, G.R. THOMAS et al. 1997. Prevention of thrombocytopenia by thrombopoietin in myelosuppressed rhesus monkeys accompanied by prominent erythropoietic stimulation and iron depletion. Blood 90: 58-63.
34. AKAHORI, H., K. SHIBUYA, M. OBUCHI et al. 1996. Effect of recombinant human thrombopoietin in nonhuman primates with chemotherapy-induced thrombocytopenia. Br. J. Haematol. 94: 722-728.
35. -) human hematopoietic cells: novel responses to Flt-3 ligand and thrombopoietin. J. Exp. Med. 183: 2551-2558.
36. PIACIBELLO, W., F. SANAVIO, L. GARETTO et al. 1997. Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood. Blood 89: 2644-2653.
37. ROWE, J.M. & J.L. LIESVELD. 1997. Hematopoietic growth factors in acute leukemia. Leukemia 11: 328-341.
38. SHIVDASANI, R.A. & S.H. ORKIN. 1996. The transcriptional control of hematopoiesis. Blood 87: 4025-4039.