-
1
-
-
0028339820
-
Bioreductive drugs for cancer therapy: The search for tumor specificity
-
Adams GE and Stratford IJ (1994) Bioreductive drugs for cancer therapy: the search for tumor specificity. Int J Radiat Oncol Biol Phys 29: 231-238
-
(1994)
Int J Radiat Oncol Biol Phys
, vol.29
, pp. 231-238
-
-
Adams, G.E.1
Stratford, I.J.2
-
2
-
-
0030880088
-
Soy feeding induces phase II enzymes in rat tissues
-
Appelt LC and Reicks MM (1997) Soy feeding induces phase II enzymes in rat tissues. Nutr Cancer 28: 270-275
-
(1997)
Nutr Cancer
, vol.28
, pp. 270-275
-
-
Appelt, L.C.1
Reicks, M.M.2
-
3
-
-
0029804277
-
Development and validation of a spectrophotometric assay for measuring the activity of NADH: Cytochrome b5 reductase in human tumour cells
-
Barham HM, Inglis R, Chinje EC and Stratford IJ (1996) Development and validation of a spectrophotometric assay for measuring the activity of NADH: cytochrome b5 reductase in human tumour cells. Br J Cancer 74: 1188-1193
-
(1996)
Br J Cancer
, vol.74
, pp. 1188-1193
-
-
Barham, H.M.1
Inglis, R.2
Chinje, E.C.3
Stratford, I.J.4
-
4
-
-
0029121481
-
Nicotinamide adenine dinucleotide (phosphate): Quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumour quinones: Quinone cytotoxicity and selectivity in human lung and breast cancer cell lines
-
Beall HD, Murphey AM, Siegel D, Hargreaves RH, Butler J and Ross D (1995) Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumour quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines. Mol Pharmacol 48: 499-504
-
(1995)
Mol Pharmacol
, vol.48
, pp. 499-504
-
-
Beall, H.D.1
Murphey, A.M.2
Siegel, D.3
Hargreaves, R.H.4
Butler, J.5
Ross, D.6
-
5
-
-
0029969531
-
Role of NAD(P)H:Quinone oxidoreductase (DT-diaphorase) in cytotoxicity and induction of DNA damage by streptonigrin
-
Beall HD, Liu YF, Siegel D, Bolton EM, Gibson NW and Ross D (1996) Role of NAD(P)H:quinone oxidoreductase (DT-diaphorase) in cytotoxicity and induction of DNA damage by streptonigrin. Biochem Pharmacol 51: 645-652
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 645-652
-
-
Beall, H.D.1
Liu, Y.F.2
Siegel, D.3
Bolton, E.M.4
Gibson, N.W.5
Ross, D.6
-
6
-
-
0030913953
-
Phase II trial of tirapazamine combined with cisplatin in chemotherapy of advanced malignant melanoma
-
Bedikian AY, Legha SS, Eton O, Buzaid AC, Papadopoulos N, Coates S, Simmons T, Neefe J and von Roemeling R (1997) Phase II trial of tirapazamine combined with cisplatin in chemotherapy of advanced malignant melanoma. Ann Oncol 8: 363-367
-
(1997)
Ann Oncol
, vol.8
, pp. 363-367
-
-
Bedikian, A.Y.1
Legha, S.S.2
Eton, O.3
Buzaid, A.C.4
Papadopoulos, N.5
Coates, S.6
Simmons, T.7
Neefe, J.8
Von Roemeling, R.9
-
7
-
-
0024328012
-
Increased sensitivity of quinone resistant cells to mitomycin C
-
Begleiter A, Robotham E, Lacey G and Leith MK (1989) Increased sensitivity of quinone resistant cells to mitomycin C. Cancer Lett 45: 173-176
-
(1989)
Cancer Lett
, vol.45
, pp. 173-176
-
-
Begleiter, A.1
Robotham, E.2
Lacey, G.3
Leith, M.K.4
-
8
-
-
0027051111
-
The role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under hypoxia
-
Begleiter A, Robotham E and Leith MK (1992) The role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under hypoxia. Mol Pharmacol 41: 677-683
-
(1992)
Mol Pharmacol
, vol.41
, pp. 677-683
-
-
Begleiter, A.1
Robotham, E.2
Leith, M.K.3
-
9
-
-
0028869125
-
Comparison of antitumor activities of 2-chlorodeoxyadenosine and 9-β-arabinosyl-2-fluoroadenine in chronic lymphocytic leukemia and marrow cells in vitro
-
Begleiter A, Verburg L, Ashique A, Lee K, Israels LG, Mowat MRA and Johnston JB (1995) Comparison of antitumor activities of 2-chlorodeoxyadenosine and 9-β-arabinosyl-2-fluoroadenine in chronic lymphocytic leukemia and marrow cells in vitro. Leukemia 9: 1875-1881
-
(1995)
Leukemia
, vol.9
, pp. 1875-1881
-
-
Begleiter, A.1
Verburg, L.2
Ashique, A.3
Lee, K.4
Israels, L.G.5
Mowat, M.R.A.6
Johnston, J.B.7
-
10
-
-
0029950920
-
Induction of DT-diaphorase by 1,2-dithiole-3-thione and increase of antitumour activity of bioreductive agents
-
Begleiter A, Leith MK and Curphey TJ (1996) Induction of DT-diaphorase by 1,2-dithiole-3-thione and increase of antitumour activity of bioreductive agents. Br J Cancer 74: S9-S14
-
(1996)
Br J Cancer
, vol.74
-
-
Begleiter, A.1
Leith, M.K.2
Curphey, T.J.3
-
11
-
-
0030028739
-
Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:Cytochrome C (P450) reductase
-
Belcourt MF, Hodnick WF, Rockwell S and Sartorelli AC (1996) Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome C (P450) reductase. Proc Natl Acad Sci USA 93: 456-460
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 456-460
-
-
Belcourt, M.F.1
Hodnick, W.F.2
Rockwell, S.3
Sartorelli, A.C.4
-
12
-
-
0027268350
-
NAD(P)H:Quinone oxidoreductase I (DT-diaphorase) expression in normal and tumor tissues
-
Belinsky M and Jaiswal AL (1993) NAD(P)H:quinone oxidoreductase I (DT-diaphorase) expression in normal and tumor tissues. Cancer Metastasis Rev 12: 103-117
-
(1993)
Cancer Metastasis Rev
, vol.12
, pp. 103-117
-
-
Belinsky, M.1
Jaiswal, A.L.2
-
13
-
-
0023917069
-
The anticancer enzyme DT diaphorase is induced selectively in liver during ascites hepatoma growth
-
Beyer RE, Segura Aguilar JE and Ernster L (1988) The anticancer enzyme DT diaphorase is induced selectively in liver during ascites hepatoma growth. Anticancer Res 8: 233-238
-
(1988)
Anticancer Res
, vol.8
, pp. 233-238
-
-
Beyer, R.E.1
Segura Aguilar, J.E.2
Ernster, L.3
-
14
-
-
0031297958
-
Bioreductive agents: A clinical update
-
Boyer MJ (1997) Bioreductive agents: a clinical update. Oncol Res 9: 391-395
-
(1997)
Oncol Res
, vol.9
, pp. 391-395
-
-
Boyer, M.J.1
-
15
-
-
0027230794
-
The use of mitomycin in esophageal cancer
-
Coia LR (1993) The use of mitomycin in esophageal cancer. Oncology 50: 53-62
-
(1993)
Oncology
, vol.50
, pp. 53-62
-
-
Coia, L.R.1
-
16
-
-
0027155256
-
Mitomycin in anal canal carcinoma
-
Cummings BJ, Keane TJ, O'Sullivan B, Wong CS and Catton CN (1993) Mitomycin in anal canal carcinoma. Oncology 50: 63-69
-
(1993)
Oncology
, vol.50
, pp. 63-69
-
-
Cummings, B.J.1
Keane, T.J.2
O'Sullivan, B.3
Wong, C.S.4
Catton, C.N.5
-
17
-
-
0031888590
-
Induction of DT-diaphorase by 1,2-dithiole-3-thiones in human tumour and normal cells and effect on anti-tumour activity of bioreductive agents
-
Doherty GP, Leith MK, Wang X, Curphey TJ and Begleiter A (1998) Induction of DT-diaphorase by 1,2-dithiole-3-thiones in human tumour and normal cells and effect on anti-tumour activity of bioreductive agents. Br J Cancer 77: 1241-1252
-
(1998)
Br J Cancer
, vol.77
, pp. 1241-1252
-
-
Doherty, G.P.1
Leith, M.K.2
Wang, X.3
Curphey, T.J.4
Begleiter, A.5
-
18
-
-
0028178821
-
Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones
-
Egner PA, Kensler TW, Prestera T, Talalay P, Libby AH, Joyner HH and Curphey TJ (1994) Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones. Carcinogenesis 15: 177-181
-
(1994)
Carcinogenesis
, vol.15
, pp. 177-181
-
-
Egner, P.A.1
Kensler, T.W.2
Prestera, T.3
Talalay, P.4
Libby, A.H.5
Joyner, H.H.6
Curphey, T.J.7
-
19
-
-
0029917028
-
Reductase enzyme expression across the National Cancer Institute tumor cell line panel: Correlation with sensitivity to mitomycin C and EO9
-
Fitzsimmons SA, Workman P, Grever M, Paull K, Camalier R and Lewis AD (1996) Reductase enzyme expression across the National Cancer Institute tumor cell line panel: correlation with sensitivity to mitomycin C and EO9. J Natl Cancer Inst 88: 259-269
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 259-269
-
-
Fitzsimmons, S.A.1
Workman, P.2
Grever, M.3
Paull, K.4
Camalier, R.5
Lewis, A.D.6
-
20
-
-
0031928663
-
Further evidence for the value of the chemosensitivity test in deciding appropriate chemotherapy for advanced gastric cancer
-
Fujita K, Kubota T, Matsuzaki SW, Otani Y, Watanabe M, Teramoto T, Kumai K and Kitajima M (1998) Further evidence for the value of the chemosensitivity test in deciding appropriate chemotherapy for advanced gastric cancer. Anticancer Res 18: 1973-1978
-
(1998)
Anticancer Res
, vol.18
, pp. 1973-1978
-
-
Fujita, K.1
Kubota, T.2
Matsuzaki, S.W.3
Otani, Y.4
Watanabe, M.5
Teramoto, T.6
Kumai, K.7
Kitajima, M.8
-
21
-
-
0026639837
-
Bioactivation of mitomycin C by xanthine dehydrogenase from EMT6 mouse mammary carcinoma tumors
-
Gustafson DL and Pritsos CA (1992) Bioactivation of mitomycin C by xanthine dehydrogenase from EMT6 mouse mammary carcinoma tumors. J Natl Cancer Inst 84: 1180-1185
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 1180-1185
-
-
Gustafson, D.L.1
Pritsos, C.A.2
-
22
-
-
0016275313
-
Glutathione S-transferase. The first enzymatic step in mercapturic acid formation
-
Habig WH, Pabst MJ and Jakoby WB (1974) Glutathione S-transferase. The first enzymatic step in mercapturic acid formation. J Biol Chem 249: 7130-7139
-
(1974)
J Biol Chem
, vol.249
, pp. 7130-7139
-
-
Habig, W.H.1
Pabst, M.J.2
Jakoby, W.B.3
-
23
-
-
0027429970
-
Reductive activation of mitomycin C by NADH:Cytochrome b5 reductase
-
Hodnick WF and Sartorelli AC (1993) Reductive activation of mitomycin C by NADH:cytochrome b5 reductase. Cancer Res 53: 4907-4912
-
(1993)
Cancer Res
, vol.53
, pp. 4907-4912
-
-
Hodnick, W.F.1
Sartorelli, A.C.2
-
24
-
-
0027222658
-
Mitomycin: Its evolving role in the treatment of breast cancer
-
Hortobagyi GN (1993) Mitomycin: its evolving role in the treatment of breast cancer. Oncology 50: 1-8
-
(1993)
Oncology
, vol.50
, pp. 1-8
-
-
Hortobagyi, G.N.1
-
25
-
-
0026319263
-
Human NAD(P)H:Quinone oxidoreductase (NQO 1) gene structure and induction by dioxin
-
Jaiswal AK (1991) Human NAD(P)H:quinone oxidoreductase (NQO 1) gene structure and induction by dioxin. Biochemistry 30: 10647-10653
-
(1991)
Biochemistry
, vol.30
, pp. 10647-10653
-
-
Jaiswal, A.K.1
-
26
-
-
0025018844
-
Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:Quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6
-
Jaiswal AK, Burnett P, Adesnik M and McBride OW (1990) Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6. Biochemistry 29: 1899-1906
-
(1990)
Biochemistry
, vol.29
, pp. 1899-1906
-
-
Jaiswal, A.K.1
Burnett, P.2
Adesnik, M.3
McBride, O.W.4
-
27
-
-
0028207539
-
Combination therapy with nucleoside analogs and alkylating agents
-
Johnston JB, Verburg L, Shore T, Williams M, Israels LG and Begleiter A (1994) Combination therapy with nucleoside analogs and alkylating agents. Leukemia 8: S140-S143
-
(1994)
Leukemia
, vol.8
-
-
Johnston, J.B.1
Verburg, L.2
Shore, T.3
Williams, M.4
Israels, L.G.5
Begleiter, A.6
-
28
-
-
0029095529
-
Oltipraz: Clinical opportunities for cancer chemoprevention
-
Kensler TW and Helzlsouer KJ (1995) Oltipraz: clinical opportunities for cancer chemoprevention. J Cell Biochem Suppl. 22: 101-107
-
(1995)
J Cell Biochem
, vol.22
, Issue.SUPPL.
, pp. 101-107
-
-
Kensler, T.W.1
Helzlsouer, K.J.2
-
29
-
-
0025326586
-
Chemosensitivity testing of fresh human leukemia cells using both a dye exclusion assay and a tetrazolium dye (MTT) assay
-
Kirkpatrick DL, Duke M and Goh TS (1990) Chemosensitivity testing of fresh human leukemia cells using both a dye exclusion assay and a tetrazolium dye (MTT) assay. Leuk Res 14: 459-466
-
(1990)
Leuk Res
, vol.14
, pp. 459-466
-
-
Kirkpatrick, D.L.1
Duke, M.2
Goh, T.S.3
-
30
-
-
0017265763
-
Studies related to antitumor antibiotics. Part V. Reaction of mitomycin C with DNA examined by ethidium fluorescence assay
-
Lown JW, Begleiter A, Johnson D and Morgan AR (1976) Studies related to antitumor antibiotics. Part V. Reaction of mitomycin C with DNA examined by ethidium fluorescence assay. Can J Biochem 54: 110-119
-
(1976)
Can J Biochem
, vol.54
, pp. 110-119
-
-
Lown, J.W.1
Begleiter, A.2
Johnson, D.3
Morgan, A.R.4
-
31
-
-
0026700546
-
Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: Relationship to the response of lung tumor xenografts to mitomycin C
-
Malkinson AM, Siegel D, Forrest GL, Gazdar AF, Oic HK, Chan DC, Bunn PA, Mabry M, Dykes DJ, Harrison SD and Ross D (1992) Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: relationship to the response of lung tumor xenografts to mitomycin C. Cancer Res 52: 4752-4757
-
(1992)
Cancer Res
, vol.52
, pp. 4752-4757
-
-
Malkinson, A.M.1
Siegel, D.2
Forrest, G.L.3
Gazdar, A.F.4
Oic, H.K.5
Chan, D.C.6
Bunn, P.A.7
Mabry, M.8
Dykes, D.J.9
Harrison, S.D.10
Ross, D.11
-
32
-
-
0031428462
-
Mechanism of action of dietary chemoprotective agents in rat liver: Induction of phase I and II drug metabolizing enzymes and aflatoxin B1 metabolism
-
Manson MM, Ball HW, Barrett MC, Clark HL, Judah DJ, Williamson G and Neal GE (1997) Mechanism of action of dietary chemoprotective agents in rat liver: induction of phase I and II drug metabolizing enzymes and aflatoxin B1 metabolism. Carcinogenesis 18: 1729-1738
-
(1997)
Carcinogenesis
, vol.18
, pp. 1729-1738
-
-
Manson, M.M.1
Ball, H.W.2
Barrett, M.C.3
Clark, H.L.4
Judah, D.J.5
Williamson, G.6
Neal, G.E.7
-
33
-
-
0030768982
-
DT-diaphorase and cytochrome b, reductase in human lung and breast tumours
-
Marin A, Lopez de Cerain A, Hamilton E, Lewis AD, Martinez-Penuela JM, Idoate MA and Bello J (1997) DT-diaphorase and cytochrome b, reductase in human lung and breast tumours. Br J Cancer 76: 923-929
-
(1997)
Br J Cancer
, vol.76
, pp. 923-929
-
-
Marin, A.1
Lopez De Cerain, A.2
Hamilton, E.3
Lewis, A.D.4
Martinez-Penuela, J.M.5
Idoate, M.A.6
Bello, J.7
-
34
-
-
0022532889
-
Modification of the cytotoxic activity of mitomycin C by oxygen and ascorbic acid in Chinese hamster ovary cells and a repair deficient mutant
-
Marshall RS and Rauth AM (1986) Modification of the cytotoxic activity of mitomycin C by oxygen and ascorbic acid in Chinese hamster ovary cells and a repair deficient mutant. Cancer Res 46: 2709-2713
-
(1986)
Cancer Res
, vol.46
, pp. 2709-2713
-
-
Marshall, R.S.1
Rauth, A.M.2
-
35
-
-
0029929226
-
DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines
-
Mikami K, Naito M, Tomida A, Yamada M, Sirakusa T and Tsuruo T (1996) DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines. Cancer Res 56: 2823-2826
-
(1996)
Cancer Res
, vol.56
, pp. 2823-2826
-
-
Mikami, K.1
Naito, M.2
Tomida, A.3
Yamada, M.4
Sirakusa, T.5
Tsuruo, T.6
-
36
-
-
0031462199
-
Phase II study of the combination of the novel bioreductive agent, tirapazamine, with cisplatin in patients with advanced non small cell lung cancer
-
Miller VA, Ng KK, Grant SC, Kindler H, Pizzo B, Heelan RT, von Roemeling R and Kris MG (1997) Phase II study of the combination of the novel bioreductive agent, tirapazamine, with cisplatin in patients with advanced non small cell lung cancer. Ann Oncol 8: 1269-1271
-
(1997)
Ann Oncol
, vol.8
, pp. 1269-1271
-
-
Miller, V.A.1
Ng, K.K.2
Grant, S.C.3
Kindler, H.4
Pizzo, B.5
Heelan, R.T.6
Von Roemeling, R.7
Kris, M.G.8
-
37
-
-
0027516583
-
Relevance of DT-diaphorase activity to mitomycin C (MMC) efficacy on human cancer cells: Differences in in vitro and in vivo systems
-
Nishiyama M, Saeki S, Aogi K, Hirabayashi N and Toge T (1993) Relevance of DT-diaphorase activity to mitomycin C (MMC) efficacy on human cancer cells: differences in in vitro and in vivo systems. Int J Cancer 53: 1013-1016
-
(1993)
Int J Cancer
, vol.53
, pp. 1013-1016
-
-
Nishiyama, M.1
Saeki, S.2
Aogi, K.3
Hirabayashi, N.4
Toge, T.5
-
38
-
-
0030787605
-
Molecular targeting of mitomycin C chemotherapy
-
Nishiyama M, Suzuki K, Kumazaki T, Yamamoto W, Toge T, Okamura T and Kurisu K (1997) Molecular targeting of mitomycin C chemotherapy. Int J Cancer 72: 649-656
-
(1997)
Int J Cancer
, vol.72
, pp. 649-656
-
-
Nishiyama, M.1
Suzuki, K.2
Kumazaki, T.3
Yamamoto, W.4
Toge, T.5
Okamura, T.6
Kurisu, K.7
-
39
-
-
0028282993
-
Relative importance of DT-diaphorase and hypoxia in the bioactivation of EO9 by human lung tumor cell lines
-
Plumb JA, Gerritsen M, Milroy R, Thomson P and Workman P (1994) Relative importance of DT-diaphorase and hypoxia in the bioactivation of EO9 by human lung tumor cell lines. Int J Radiat Oncol Biol Phys 29: 295-299
-
(1994)
Int J Radiat Oncol Biol Phys
, vol.29
, pp. 295-299
-
-
Plumb, J.A.1
Gerritsen, M.2
Milroy, R.3
Thomson, P.4
Workman, P.5
-
41
-
-
0022622807
-
Generation of reactive oxygen radicals through bioactivation of mitomycin C antibiotics
-
Pritsos CA and Sartorelli AC (1986) Generation of reactive oxygen radicals through bioactivation of mitomycin C antibiotics. Cancer Res 46: 3528-3532
-
(1986)
Cancer Res
, vol.46
, pp. 3528-3532
-
-
Pritsos, C.A.1
Sartorelli, A.C.2
-
42
-
-
0023930873
-
Direct measurement of NAD(P)H:Quinone reductase from cells cultured in microliter wells: A screening assay for anticarcinogenic enzyme inducers
-
Prochaska HJ and Santamaria AB (1988) Direct measurement of NAD(P)H:quinone reductase from cells cultured in microliter wells: a screening assay for anticarcinogenic enzyme inducers. Anal Biochem 169: 328-336
-
(1988)
Anal Biochem
, vol.169
, pp. 328-336
-
-
Prochaska, H.J.1
Santamaria, A.B.2
-
43
-
-
0026612119
-
DT-diaphorase and cancer chemotherapy
-
Riley RJ and Workman P (1992) DT-diaphorase and cancer chemotherapy. Biochem Pharmacol 43: 1657-1669
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 1657-1669
-
-
Riley, R.J.1
Workman, P.2
-
45
-
-
0027295491
-
DT-diaphorase in activation and detoxification of quinones
-
Ross D, Siegel D, Beall H, Prakash AS, Mulcahy RT and Gibson NW (1993) DT-diaphorase in activation and detoxification of quinones. Cancer Metastasis Rev 12: 83-101
-
(1993)
Cancer Metastasis Rev
, vol.12
, pp. 83-101
-
-
Ross, D.1
Siegel, D.2
Beall, H.3
Prakash, A.S.4
Mulcahy, R.T.5
Gibson, N.W.6
-
46
-
-
0028610410
-
Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies
-
Ross D, Beall H, Travel RD, Siegel D, Phillips RM and Gibson NW (1994) Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies. Oncol Res 6: 493-500
-
(1994)
Oncol Res
, vol.6
, pp. 493-500
-
-
Ross, D.1
Beall, H.2
Travel, R.D.3
Siegel, D.4
Phillips, R.M.5
Gibson, N.W.6
-
47
-
-
0028338822
-
Phase I and pharmacologic study of the novel indoloquinone bioreductive alkylating cytotoxic drug EO9
-
Schellens JHM, Planting AST, Van Acker BAC, Loos WJ, De Boer-Dennert M, Van der Burg MEL, Koier I, Krediet RT, Stoter G and Verweij J (1994) Phase I and pharmacologic study of the novel indoloquinone bioreductive alkylating cytotoxic drug EO9. J Natl Cancer Inst 86: 906-912
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 906-912
-
-
Schellens, J.H.M.1
Planting, A.S.T.2
Van Acker, B.A.C.3
Loos, W.J.4
De Boer-Dennert, M.5
Van Der Burg, M.E.L.6
Koier, I.7
Krediet, R.T.8
Stoter, G.9
Verweij, J.10
-
48
-
-
0025248106
-
Cytosolic NAD(P)H: (quinone acceptor) oxidoreductase in human normal and tumor tissue: Effects of cigarette smoking and alcohol
-
Schlager JJ and Powis G (1990) Cytosolic NAD(P)H: (quinone acceptor) oxidoreductase in human normal and tumor tissue: effects of cigarette smoking and alcohol. Int J Cancer 45: 403-409
-
(1990)
Int J Cancer
, vol.45
, pp. 403-409
-
-
Schlager, J.J.1
Powis, G.2
-
49
-
-
0028783332
-
DT diaphorase activity in normal and neoplastic human tissues: An indicator of sensitivity to bioreductive agents?
-
Smitskamp-Wilms E, Giaccone G, Pinedo HM, Van der Laan BFAM and Peters GJ (1995) DT diaphorase activity in normal and neoplastic human tissues: an indicator of sensitivity to bioreductive agents? Br J Cancer 72: 917-921
-
(1995)
Br J Cancer
, vol.72
, pp. 917-921
-
-
Smitskamp-Wilms, E.1
Giaccone, G.2
Pinedo, H.M.3
Van Der Laan, B.F.A.M.4
Peters, G.J.5
-
50
-
-
0027157693
-
The case for mitomycin in non-small cell lung cancer
-
Spain RC (1993) The case for mitomycin in non-small cell lung cancer. Oncology 50: 35-52
-
(1993)
Oncology
, vol.50
, pp. 35-52
-
-
Spain, R.C.1
-
51
-
-
0017795019
-
Purification and properties of NADPH cytochrome P-450 reductase
-
Strobel HW and Dignam JD (1978) Purification and properties of NADPH cytochrome P-450 reductase. Methods Enzymol 52: 89-96
-
(1978)
Methods Enzymol
, vol.52
, pp. 89-96
-
-
Strobel, H.W.1
Dignam, J.D.2
-
52
-
-
0023123806
-
Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA
-
Tomasz M, Lipman R, Chowdary D, Pawlak L, Verdine GL and Nakanishi K (1987) Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science 235: 1204-1208
-
(1987)
Science
, vol.235
, pp. 1204-1208
-
-
Tomasz, M.1
Lipman, R.2
Chowdary, D.3
Pawlak, L.4
Verdine, G.L.5
Nakanishi, K.6
-
53
-
-
0028786534
-
Induction of NAD(P)H:Quinone reductase by vitamins A, E, and C in Colo205 cancer cells
-
Wang W and Higuchi CM (1995) Induction of NAD(P)H:quinone reductase by vitamins A, E, and C in Colo205 cancer cells. Cancer Lett 98: 63-69
-
(1995)
Cancer Lett
, vol.98
, pp. 63-69
-
-
Wang, W.1
Higuchi, C.M.2
-
54
-
-
3543046764
-
New aziridinylbenzoquinones as NAD(P)H:Quinone oxidoreductase (NQO 1)-directed antitumor agents
-
Winski SL, Hargreaves RHJ, Butler J and Ross D (1998) New aziridinylbenzoquinones as NAD(P)H:quinone oxidoreductase (NQO 1)-directed antitumor agents. Proc Am J Assoc Cancer Res 29: 303
-
(1998)
Proc Am J Assoc Cancer Res
, vol.29
, pp. 303
-
-
Winski, S.L.1
Hargreaves, R.H.J.2
Butler, J.3
Ross, D.4
-
55
-
-
0027328452
-
The experimental development of bioreductive drugs and their role in cancer therapy
-
Workman P and Stratford IJ (1993) The experimental development of bioreductive drugs and their role in cancer therapy. Cancer Metastasis Rev 12: 73-82
-
(1993)
Cancer Metastasis Rev
, vol.12
, pp. 73-82
-
-
Workman, P.1
Stratford, I.J.2
-
56
-
-
0028060572
-
Characterization of a human bladder cancer cell line selected for resistance to mitomycin C
-
Xu BH, Gupta V and Singh SV (1994) Characterization of a human bladder cancer cell line selected for resistance to mitomycin C. Int J Cancer 58: 686-692
-
(1994)
Int J Cancer
, vol.58
, pp. 686-692
-
-
Xu, B.H.1
Gupta, V.2
Singh, S.V.3
-
57
-
-
0028203252
-
Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates
-
Zhang Y, Kensler TW, Cho CG, Posner GH and Talalay P (1994) Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. Proc Natl Acad Sci USA 91: 3147-3150
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3147-3150
-
-
Zhang, Y.1
Kensler, T.W.2
Cho, C.G.3
Posner, G.H.4
Talalay, P.5
|