Induction of DT-diaphorase by 1,2-dithiole-3-thiones in human tumour and normal cells and effect on anti tumour activity of bioreductive agents

British Journal of Cancer

Volumn 77, Issue 8, 1998, Pages 1241-1252

  Doherty, G P ^a,b   Leith, M K ^a,b   Wang, X ^a,b   Curphey, T J ^c   Begleiter, A ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c DARTMOUTH COLLEGE   (United States)

Author keywords

1,2 dithiole 3 thiones; Bioreductive agent; DT diaphorase; Human tumour; Induction

Indexed keywords

1,2 DITHIOLE 3 THIONE DERIVATIVE; 5 (1 AZIRIDINYL) 3 HYDROXYMETHYL 2 (3 HYDROXY 1 PROPENYL) 1 METHYL 4,7 INDOLEDIONE; MITOMYCIN C; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW CELL; DRUG CYTOTOXICITY; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; KIDNEY CELL; LUNG ALVEOLUS CELL; PRIORITY JOURNAL; TUMOR CELL LINE;

EID: 0031888590     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.209     Document Type: Article

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