메뉴 건너뛰기




Volumn 32, Issue 5, 1999, Pages 990-1001

Pore-forming activity is not sufficient for Legionella pneumophila phagosome trafficking and intracellular growth

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT;

EID: 0033019702     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1999.01410.x     Document Type: Article
Times cited : (106)

References (45)
  • 1
    • 0031937678 scopus 로고    scopus 로고
    • Identification of linked Legionella pneumophila genes essential for intracellular growth and evasion of the endocytic pathway
    • Andrews, H.L., Vogel, J.P., and Isberg, R.R. (1998) Identification of linked Legionella pneumophila genes essential for intracellular growth and evasion of the endocytic pathway. Infect Immun 66: 950-958.
    • (1998) Infect Immun , vol.66 , pp. 950-958
    • Andrews, H.L.1    Vogel, J.P.2    Isberg, R.R.3
  • 2
    • 0001211310 scopus 로고
    • Response of cultured macrophages to M. tuberculosis with observations on fusion of lysosomes with phagosomes
    • Armstrong, J.A., and Hart, P.D. (1971) Response of cultured macrophages to M. tuberculosis with observations on fusion of lysosomes with phagosomes. J Exp Med 134: 713-740.
    • (1971) J Exp Med , vol.134 , pp. 713-740
    • Armstrong, J.A.1    Hart, P.D.2
  • 3
    • 0028126694 scopus 로고
    • Localization and topology of VirB proteins of Agrobacterium tumefaciens
    • Beijersbergen, A., Smith, S.J., and Hooykaas, P.J. (1994) Localization and topology of VirB proteins of Agrobacterium tumefaciens. Plasmid 32: 212-218.
    • (1994) Plasmid , vol.32 , pp. 212-218
    • Beijersbergen, A.1    Smith, S.J.2    Hooykaas, P.J.3
  • 4
    • 0027472133 scopus 로고
    • Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila
    • Berger, K.H., and Isberg, R.R. (1993) Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila. Mol Microbiol 7: 7-19.
    • (1993) Mol Microbiol , vol.7 , pp. 7-19
    • Berger, K.H.1    Isberg, R.R.2
  • 5
    • 0028104489 scopus 로고
    • Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene
    • Berger, K.H., Merriam, J.J., and Isberg, R.R. (1994) Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene. Mol Microbiol 14: 809-822.
    • (1994) Mol Microbiol , vol.14 , pp. 809-822
    • Berger, K.H.1    Merriam, J.J.2    Isberg, R.R.3
  • 6
    • 0028030168 scopus 로고
    • The Legionella pneumophila icm locus: A set of genes required for intracellular multiplication in human macrophages
    • Brand, B.C., Sadosky, A.B., and Shuman, H.A. (1994) The Legionella pneumophila icm locus: a set of genes required for intracellular multiplication in human macrophages. Mol Microbiol 14: 797-808.
    • (1994) Mol Microbiol , vol.14 , pp. 797-808
    • Brand, B.C.1    Sadosky, A.B.2    Shuman, H.A.3
  • 7
    • 0021183978 scopus 로고
    • Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity
    • Celada, A., Gray, P.W., Rinderknecht, E., and Schreiber, R.D. (1984) Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity. J Exp Med 160: 55-74.
    • (1984) J Exp Med , vol.160 , pp. 55-74
    • Celada, A.1    Gray, P.W.2    Rinderknecht, E.3    Schreiber, R.D.4
  • 8
    • 0025363426 scopus 로고
    • Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments
    • Chavrier, P., Parton, R.G., Hauri, H.P., Simons, K., and Zerial, M. (1990) Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments. Cell 62: 317-329.
    • (1990) Cell , vol.62 , pp. 317-329
    • Chavrier, P.1    Parton, R.G.2    Hauri, H.P.3    Simons, K.4    Zerial, M.5
  • 9
    • 0022258568 scopus 로고
    • Lysosome-associated membrane proteins: Characterization of LAMP-1 of macrophage P388 and mouse embryo 3T3 cultured cells
    • Chen, J.W., Pan, W., D'Souza, M.P., and August, J.T. (1985) Lysosome-associated membrane proteins: characterization of LAMP-1 of macrophage P388 and mouse embryo 3T3 cultured cells. Arch Biochem Biophys 239: 574-586.
    • (1985) Arch Biochem Biophys , vol.239 , pp. 574-586
    • Chen, J.W.1    Pan, W.2    D'Souza, M.P.3    August, J.T.4
  • 10
    • 0029846007 scopus 로고    scopus 로고
    • Requirement for exported proteins in secretion through the invasion-associated type III system of Salmonella typhimurium
    • Collazo, C.M., and Galan, J.E. (1996) Requirement for exported proteins in secretion through the invasion-associated type III system of Salmonella typhimurium. Infect Immun 64: 3524-3531.
    • (1996) Infect Immun , vol.64 , pp. 3524-3531
    • Collazo, C.M.1    Galan, J.E.2
  • 11
    • 0031007757 scopus 로고    scopus 로고
    • The invasion-associated type III system of Salmonella typhimurium directs the translocation of Sip proteins into the host cell
    • Collazo, C.M., and Galan, J.E. (1997) The invasion-associated type III system of Salmonella typhimurium directs the translocation of Sip proteins into the host cell. Mol Microbiol 24: 747-756.
    • (1997) Mol Microbiol , vol.24 , pp. 747-756
    • Collazo, C.M.1    Galan, J.E.2
  • 12
    • 0028328732 scopus 로고
    • Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus
    • Desjardins, M., Huber, L.S., Parton, R.G., and Griffiths, G. (1994) Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus. J Cell Biol 124: 677-688.
    • (1994) J Cell Biol , vol.124 , pp. 677-688
    • Desjardins, M.1    Huber, L.S.2    Parton, R.G.3    Griffiths, G.4
  • 15
    • 0003448569 scopus 로고
    • Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
    • Harlow, E., and Lane, D. (1988) Antibodies: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
    • (1988) Antibodies: A Laboratory Manual
    • Harlow, E.1    Lane, D.2
  • 16
    • 0021014278 scopus 로고
    • The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome lysosome fusion in human monocytes
    • Horwitz, M.A. (1983a) The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome lysosome fusion in human monocytes. J Exp Med 158: 2108-2126.
    • (1983) J Exp Med , vol.158 , pp. 2108-2126
    • Horwitz, M.A.1
  • 17
    • 0020591330 scopus 로고
    • Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes
    • Horwitz, M.A. (1983b) Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes. J Exp Med 158: 1319-1331.
    • (1983) J Exp Med , vol.158 , pp. 1319-1331
    • Horwitz, M.A.1
  • 18
    • 0021718023 scopus 로고
    • Legionella pneumophila inhibits acidification of its phagosome in human monocytes
    • Horwitz, M.A., and Maxfield, F.R. (1984) Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol 99: 1936-1943.
    • (1984) J Cell Biol , vol.99 , pp. 1936-1943
    • Horwitz, M.A.1    Maxfield, F.R.2
  • 19
    • 0018885613 scopus 로고
    • Legionnaires' disease bacterium (Legionella pneumophila) multiplies intracellularly in human monocytes
    • Horwitz, M.A., and Silverstein, S.C. (1980) Legionnaires' disease bacterium (Legionella pneumophila) multiplies intracellularly in human monocytes. J Clin Invest 66: 441-450.
    • (1980) J Clin Invest , vol.66 , pp. 441-450
    • Horwitz, M.A.1    Silverstein, S.C.2
  • 20
    • 0028215798 scopus 로고
    • Cytotoxicity of extracellular Legionella pneumophila
    • Husmann, L.K., and Johnson, W. (1994) Cytotoxicity of extracellular Legionella pneumophila. Infect Immun 62: 2111-2114.
    • (1994) Infect Immun , vol.62 , pp. 2111-2114
    • Husmann, L.K.1    Johnson, W.2
  • 21
    • 0027212851 scopus 로고
    • Expression of contact-dependent cytolytic activity by Mycobacterium tuberculosis and isolation of the genomic locus that encodes the activity
    • King, C.H., Mundayoor, S., Crawford, J.T., and Shinnick, T.M. (1993) Expression of contact-dependent cytolytic activity by Mycobacterium tuberculosis and isolation of the genomic locus that encodes the activity. Infect Immun 61: 2708-2712.
    • (1993) Infect Immun , vol.61 , pp. 2708-2712
    • King, C.H.1    Mundayoor, S.2    Crawford, J.T.3    Shinnick, T.M.4
  • 22
    • 0031973809 scopus 로고    scopus 로고
    • Evidence for pore-forming ability by Legionella pneumophila
    • Kirby, J.E., Vogel, J.P., Andrews, H.L., and Isberg, R.R. (1998) Evidence for pore-forming ability by Legionella pneumophila. Mol Microbiol 27: 323-336.
    • (1998) Mol Microbiol , vol.27 , pp. 323-336
    • Kirby, J.E.1    Vogel, J.P.2    Andrews, H.L.3    Isberg, R.R.4
  • 23
    • 0018224280 scopus 로고
    • Transcomplementation-dependent replication of a low molecular weight origin fragment from plasmid R6K
    • Kolter, R., Inuzuka, M., and Helinski, D.R. (1978) Transcomplementation-dependent replication of a low molecular weight origin fragment from plasmid R6K. Cell 15: 1199-1208.
    • (1978) Cell , vol.15 , pp. 1199-1208
    • Kolter, R.1    Inuzuka, M.2    Helinski, D.R.3
  • 24
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, E.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, E.K.1
  • 25
    • 0017662282 scopus 로고
    • Legionnaires' disease: Isolation of a bacterium and demonstration of its role in other respiratory diseases
    • McDade, J.E., Shepard, C.C., Fraser, D.W., Tsai, T.R., Redus, M.A., and Dowdle, W.R. (1977) Legionnaires' disease: isolation of a bacterium and demonstration of its role in other respiratory diseases. N Engl J Med 297: 1197-1203.
    • (1977) N Engl J Med , vol.297 , pp. 1197-1203
    • McDade, J.E.1    Shepard, C.C.2    Fraser, D.W.3    Tsai, T.R.4    Redus, M.A.5    Dowdle, W.R.6
  • 26
    • 0026738809 scopus 로고
    • Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages
    • Marra, A., Blander, S.J., Horwitz, M.A., and Shuman, H.A. (1992) Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages. Proc Natl Acad Sci USA 89: 9607-9611.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9607-9611
    • Marra, A.1    Blander, S.J.2    Horwitz, M.A.3    Shuman, H.A.4
  • 27
    • 0030994460 scopus 로고    scopus 로고
    • Analysis of the Legionella pneumophila flil gene: Intracellular growth of a defined mutant defective for flagellum biosynthesis
    • Merriam, J.J., Mathur, R., Maxfield-Boumil, R., and Isberg, R.R. (1997) Analysis of the Legionella pneumophila flil gene: intracellular growth of a defined mutant defective for flagellum biosynthesis. Infect Immun 65: 2497-2501.
    • (1997) Infect Immun , vol.65 , pp. 2497-2501
    • Merriam, J.J.1    Mathur, R.2    Maxfield-Boumil, R.3    Isberg, R.R.4
  • 28
    • 0023906750 scopus 로고
    • Isolation and characterization of auxotrophic mutants of Legionella pneumophila that fail to multiply in human monocytes
    • Mintz, C.S., Chen, J., and Shuman, H. (1988) Isolation and characterization of auxotrophic mutants of Legionella pneumophila that fail to multiply in human monocytes. Infect Immun 56: 1449-1455.
    • (1988) Infect Immun , vol.56 , pp. 1449-1455
    • Mintz, C.S.1    Chen, J.2    Shuman, H.3
  • 29
    • 0026019764 scopus 로고
    • A series of wide-host-range low-copy-number vectors that allow direct screening for recombinants
    • Morales, V.M., Backman, A., and Bagdasarian, M. (1991) A series of wide-host-range low-copy-number vectors that allow direct screening for recombinants. Gene 97: 39-47.
    • (1991) Gene , vol.97 , pp. 39-47
    • Morales, V.M.1    Backman, A.2    Bagdasarian, M.3
  • 30
    • 0027976793 scopus 로고
    • The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex
    • Obert, S.O., Connor, R.J., Schmid, S., and Hearing, P. (1994) The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex. Mol Cell Biol 14: 1333-1346.
    • (1994) Mol Cell Biol , vol.14 , pp. 1333-1346
    • Obert, S.O.1    Connor, R.J.2    Schmid, S.3    Hearing, P.4
  • 31
    • 0023714411 scopus 로고
    • Growth of Legionella pneumophila in a human macrophage-like (U937) cell line
    • Pearlman, E., Engleberg, N.C., and Eisenstein, B.I. (1988) Growth of Legionella pneumophila in a human macrophage-like (U937) cell line. Microb Pathog 5: 87-95.
    • (1988) Microb Pathog , vol.5 , pp. 87-95
    • Pearlman, E.1    Engleberg, N.C.2    Eisenstein, B.I.3
  • 32
    • 0026558527 scopus 로고
    • Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages
    • Rabinowitz, S., Horstmann, H., Gordon, S., and Griffiths, G. (1992) Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages. J Cell Biol 116: 95-112.
    • (1992) J Cell Biol , vol.116 , pp. 95-112
    • Rabinowitz, S.1    Horstmann, H.2    Gordon, S.3    Griffiths, G.4
  • 33
    • 0031971194 scopus 로고    scopus 로고
    • Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake
    • Roy, C.R., Berger, K., and Isberg, R.R. (1998) Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake. Mol Microbiol 28: 663-674.
    • (1998) Mol Microbiol , vol.28 , pp. 663-674
    • Roy, C.R.1    Berger, K.2    Isberg, R.R.3
  • 34
    • 0031025290 scopus 로고    scopus 로고
    • Topology of Legionella pneumophila DotA: An inner membrane protein required for replication in macrophages
    • Roy, C.R., and Isberg, R.I. (1997) Topology of Legionella pneumophila DotA: an inner membrane protein required for replication in macrophages. Infect Immun 65: 571-578.
    • (1997) Infect Immun , vol.65 , pp. 571-578
    • Roy, C.R.1    Isberg, R.I.2
  • 35
    • 0027443142 scopus 로고
    • Identification of Legionella pneumophila genes required for growth within and killing of human macrophages
    • Sadosky, A.B., Wiater, L.A., and Shuman, H.A. (1993) Identification of Legionella pneumophila genes required for growth within and killing of human macrophages. Infect Immun 61: 5361-5373.
    • (1993) Infect Immun , vol.61 , pp. 5361-5373
    • Sadosky, A.B.1    Wiater, L.A.2    Shuman, H.A.3
  • 36
    • 1842406033 scopus 로고    scopus 로고
    • Characterization of a new region required for macrophage killing by Legionella pneumophila
    • Segal, G., and Shuman, H.A. (1997) Characterization of a new region required for macrophage killing by Legionella pneumophila. Infect Immun 65: 5057-5066.
    • (1997) Infect Immun , vol.65 , pp. 5057-5066
    • Segal, G.1    Shuman, H.A.2
  • 37
    • 0032539674 scopus 로고    scopus 로고
    • Host cell killing and bacterial conjugation require overlapping sets of genes within a 22 kb region of the Legionella pneumophila genome
    • Segal, G., Purcell, M., and Shuman, H.A. (1998) Host cell killing and bacterial conjugation require overlapping sets of genes within a 22 kb region of the Legionella pneumophila genome. Proc Natl Acad Sci USA 95: 1669-1674.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1669-1674
    • Segal, G.1    Purcell, M.2    Shuman, H.A.3
  • 38
    • 0029155737 scopus 로고
    • Association of Legionella pneumophila with the macrophage endoplasmic reticulum
    • Swanson, M.S., and Isberg, R.R. (1995) Association of Legionella pneumophila with the macrophage endoplasmic reticulum. Infect Immun 63: 3609-3620.
    • (1995) Infect Immun , vol.63 , pp. 3609-3620
    • Swanson, M.S.1    Isberg, R.R.2
  • 39
    • 0029994905 scopus 로고    scopus 로고
    • Identification of Legionella pneumophila mutants that have aberrant intracellular fates
    • Swanson, M.S., and Isberg, R.I. (1996) Identification of Legionella pneumophila mutants that have aberrant intracellular fates. Infect Immun 64: 2585-2594.
    • (1996) Infect Immun , vol.64 , pp. 2585-2594
    • Swanson, M.S.1    Isberg, R.I.2
  • 40
    • 0027186527 scopus 로고
    • Subcellular localization of seven VirB proteins of Agrobacterium tumefaciens: Implications for the formation of a T-DNA transport structure
    • Thorstenson, Y.R., Kuldau, G.A., and Zambryski, P.C. (1993) Subcellular localization of seven VirB proteins of Agrobacterium tumefaciens: implications for the formation of a T-DNA transport structure. J Bacteriol 175: 5233-5241.
    • (1993) J Bacteriol , vol.175 , pp. 5233-5241
    • Thorstenson, Y.R.1    Kuldau, G.A.2    Zambryski, P.C.3
  • 41
    • 0030451548 scopus 로고    scopus 로고
    • Use of salt to isolate Legionella pneumophila mutants unable to replicate in macrophages
    • Vogel, J.P., Roy, C., and Isberg, R.R. (1996) Use of salt to isolate Legionella pneumophila mutants unable to replicate in macrophages. Ann NY Acad Sci 797: 271-272.
    • (1996) Ann NY Acad Sci , vol.797 , pp. 271-272
    • Vogel, J.P.1    Roy, C.2    Isberg, R.R.3
  • 42
    • 0032488861 scopus 로고    scopus 로고
    • Conjugative transfer by the virulence system of Legionella pneumophila
    • Vogel, J.P., Andrews, H.L., Wong, S.K., and Isberg, R.R. (1998) Conjugative transfer by the virulence system of Legionella pneumophila. Science 279: 873-876.
    • (1998) Science , vol.279 , pp. 873-876
    • Vogel, J.P.1    Andrews, H.L.2    Wong, S.K.3    Isberg, R.R.4
  • 43
    • 0029886432 scopus 로고    scopus 로고
    • Customized secretion chaperones in pathogenic bacteria
    • Wattiau, P., Woestyn, S., and Cornelis, G.R. (1996) Customized secretion chaperones in pathogenic bacteria. Mol Microbiol 20: 255-262.
    • (1996) Mol Microbiol , vol.20 , pp. 255-262
    • Wattiau, P.1    Woestyn, S.2    Cornelis, G.R.3
  • 44
    • 0031669417 scopus 로고    scopus 로고
    • Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila
    • Wiater, L.A., Dunn, K., Maxfield, F.R., and Shuman, H.A. (1998) Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila. Infect Immun 66: 4450-4460.
    • (1998) Infect Immun , vol.66 , pp. 4450-4460
    • Wiater, L.A.1    Dunn, K.2    Maxfield, F.R.3    Shuman, H.A.4
  • 45
    • 0029968272 scopus 로고    scopus 로고
    • Adaptation of a conjugal transfer system for the export of pathogenic macromolecules
    • Winans, S.C., Burns, D.L., and Christie, P.J. (1996) Adaptation of a conjugal transfer system for the export of pathogenic macromolecules. Trends Microbiol 4: 64-68.
    • (1996) Trends Microbiol , vol.4 , pp. 64-68
    • Winans, S.C.1    Burns, D.L.2    Christie, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.