Cloning, expression, and enzymatic characterization of pseudomonas aeruginosa topoisomerase IV

Antimicrobial Agents and Chemotherapy

Volumn 43, Issue 3, 1999, Pages 530-536

  Akasaka, Takaaki ^a   Onodera, Yoshikuni ^a   Tanaka, Mayumi ^a   Sato, Kenichi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); MALTOSE BINDING PROTEIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CATALYSIS; DNA FLANKING REGION; DNA REPLICATION; DNA STRAND; DNA SUPERCOILING; ENZYME ACTIVITY; GENE EXPRESSION; GENE OVEREXPRESSION; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SEQUENCE HOMOLOGY;

EID: 0033019428     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.3.530     Document Type: Article

References (49)

1. Adachi, T., M. Mizuuchi, E. Robinson, E. Appella, M. O'Dea, M. Gellert, and K. Mizuuchi. 1987. DNA sequence of the E. coli gyrB gene: application of a new sequencing strategy. Nucleic Acids Res. 15:771-783.
2. Akasaka, T., S. Kurosaka, Y. Uchida, M. Tanaka, K. Sato, and I. Hayakawa. 1998. Antibacterial activities and inhibitory effects of sitafloxacin (DU-6859a) and its optical isomers against type II topoisomerases. Antimicrob. Agents Chemother. 42:1284-1287.
3. Belland, R. J., S. G. Morrison, C. Ison, and W. M. Huang. 1994. Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates. Mol. Microbiol. 14:371-380.
4. Blanche, F., B. Cameron, F. X. Bernard, L. Maton, B. Manse, L. Ferrero, N. Ratet, C. Lecoq, A. Goniot, D. Bisch, and J. Crouzet. 1996. Differential behaviors of Staphylococcus aureus and Escherichia coli type II DNA topoisomerases. Antimicrob. Agents Chemother. 40:2714-2720.
5. Cambau, E., E. Perani, C. Dib, C. Petinon, J. Trias, and V. Jarlier. 1995. Role of mutations in DNA gyrase genes in ciprofloxacin resistance of Pseudomonas aeruginosa susceptible or resistant to imipenem. Antimicrob. Agents Chemother. 39:2248-2252.
6. Dean, F., M. A. Krasnow, R. Otter, M. M. Matzuk, S. J. Spengler, and N. R. Cozzarelli. 1983. Escherichia coli type-1 topoisomerases: identification, mechanism, and role in recombination. Cold Spring Harbor Symp. Quant. Biol. 2:769-777.
7. Drlica, K. 1992. Control of bacterial DNA supercoiling. Mol. Microbiol. 6:425-433.
8. Drlica, K., and X. Zhao. 1997. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol. Mol. Biol. Rev. 61:377-392.
9. Ferrero, L., B. Cameron, B. Manse, D. Lagneaux, J. Crouzet, A. Famechon, and F. Blanche. 1994. Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: a primary target of fluoroquinolones. Mol. Microbiol. 13:641-653.
10. Fleischmann, R. D., M. D. Adams, O. White, R. A. Clayton, E. F. Kirkness, A. R. Kerlavage, C. J. Bult, J. F. Tomb, B. A. Dougherty, J. M. Merrick, et al. 1995. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269:496-512.
11. Gellert, M., K. Mizuuchi, M. H. O'Dea, and H. A. Nash. 1976. DNA gyrase: an enzyme that introduces superhelical turns into DNA. Proc. Natl. Acad. Sci. USA 73:3872-3876.
12. Georgion, M., R. Munoz, F. Roman, R. Canton, R. Gomez-Lus, J. Campos, and A. G. De La Campa. 1996. Ciproftoxacin-resistant Haemophilus influenzae strains possess mutations in analogous positions of GyrA and ParC. Antimicrob. Agents Chemother. 40:1741-1744.
13. Heisig, P. 1996. Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli. Antimicrob. Agents Chemother. 40:879-885.
14. Horowitz, D., and J. Wang. 1987. Mapping the active site tyrosine of Escherichia coli DNA gyrase. J. Biol. Chem. 262:5339-5348.
15. Hoshino, K., A. Kitamura, I. Morrissey, K. Sato, J. Kato, and H. Ikeda. 1994. Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition. Antimicrob. Agents Chemother. 38:2623-2627.
16. Huang, W. M. 1996. Bacterial diversity based on type II DNA topoisomerase genes. Annu. Rev. Genet. 30:79-107.
17. Inoue, Y., K. Sato, T. Fujii, K. Hirai, M. Inoue, S. Iyobe, and S. Mitsuhashi. 1987. Some properties of subunits of DNA gyrase from Pseudomonas aeruginosa PAO1 and its nalidixic acid-resistant mutant. J. Bacteriol. 169:2322-2325.
18. Kato, J., Y. Nishimura, R. Imamura, H. Niki, S. Hiraga, and H. Suzuki. 1990. New topoisomerase essential for chromosome segregation in E. coli. Cell 63:393-404.
19. Kato, J., H. Suzuki, and H. Ikeda. 1992. Purification and characterization of DNA topoisomerase IV in Escherichia coli. J. Biol. Chem. 267:25676-25684.
20. Kitamura, A., K. Hoshino, Y. Kimura, I. Hayakawa, and K. Sato. 1995. Contribution of the C-8 substituent of DU-6859a, a new potent fluoroquinolone, to its activity against DNA gyrase mutants of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 39:1467-1471.
21. Kumagai, Y., J. Kato, K. Hoshino, T. Akasaka, K. Sato, and H. Ikeda. 1996. Quinolone-resistant mutants of Escherichia coli DNA topoisomerase IV parC gene. Antimicrob. Agents Chemother. 40:710-714.
22. Kureishi, A., J. M. Diver, B. Beckthold, T. Schollaardt, and L. E. Bryan. 1994. Cloning and nucleotide sequence of Pseudomonas aeruginosa DNA gyrase gyrA gene from strain PAO1 and quinolone-resistant clinical isolates. Antimicrob. Agents Chemother. 38:1944-1952.
23. Luttinger, A. 1995. The twisted 'life' of DNA in the cell: bacterial topoisomerases. Mol. Microbiol. 15:601-606.
24. Luttinger, A., A. Springer, and M. Schmid. 1991. A cluster of genes that affects nucleoid segregation in Salmonella typhimurium. New Biol. 3:687-697.
25. Masecar, B. L., R. A. Celesk, and N. J. Robillard. 1990. Analysis of acquired ciprofloxacin resistance in a clinical strain of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 34:281-286.
26. Maxwell, A. 1997. DNA gyrase as a drug target. Trends Microbiol. 5:102-109.
27. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
28. Miller, W. G., and R. W. Simons. 1993. Chromosomal supercoiling in Escherichia coli. Mol. Microbiol. 10:675-684.
29. Mouton, J. W., J. G. den Hollander, and A. M. Horrevorts. 1993. Emergence of antibiotic resistance amongst Pseudomonas aeruginosa isolates from patients with cystic fibrosis. J. Antimicrob. Chemother. 31:919-926.
30. Nakane, T., S. Iyobe, K. Sato, and S. Mitsuhashi. 1995. In vitro antibacterial activity of DU-6859a, a new fluoroquinolone. Antimicrob. Agents Chemother. 39:2822-2826.
31. Nakano, M., T. Deguchi, T. Kawamura, M. Yasuda, M. Kimura, Y. Okano, and Y. Kawada. 1997. Mutations in the gyrA and parC genes in fluoroquinolone-resistant clinical isolates of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 41:2289-2291.
32. Nikaido, H. 1996. Multidrug efflux pumps of gram-negative bacteria. J. Bacteriol. 178:5853-5859.
33. Pan, X. S., and L. M. Fisher. 1996. Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: role in fluoroquinolone resistance. J. Bacteriol. 178:4060-4069.
34. Peng, H., and K. J. Marians. 1993. Escherichia coli topoisomerase IV: purification, characterization, subunit structure, and subunit interactions. J. Biol. Chem. 268:24481-24490.
35. Peng, H., and K. J. Marians. 1993. Decatenation activity of topoisomerase IV during oriC and pBR322 DNA replication in vitro. Proc. Natl. Acad. Sci. USA 90:8571-8575.
36. Roca, J. 1995. The mechanisms of DNA topoisomerases. Trends Biochem. Sci. 20:156-160.
37. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
38. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
39. Sato, K., K. Hoshino, M. Tanaka, I. Hayakawa, and Y. Osada. 1992. Antimicrobial activity of DU-6859, a new potent fluoroquinolone, against clinical isolates. Antimicrob. Agents Chemother. 36:1491-1498.
40. Springer, A. L., and M. B. Schmid. 1993. Molecular characterization of the Salmonella typhimurium parE gene. Nucleic Acids Res. 21:1805-1809.
41. Swanberg, S., and J. Wang. 1987. Cloning and sequencing of the Escherichia coli gyrA gene coding for the A subunit of DNA gyrase. J. Mol. Biol. 197:729-736.
42. Tanaka, M., K. Hoshino, M. Hohmura, H. Ishida, A. Kitamura, K. Sato, I. Hayakawa, and T. Nishino. 1996. Effect of growth conditions on antimicrobial activity of DU-6859a and its bactericidal activity determined by the killing curve method. J. Antimicrob. Chemother. 37:1091-1102.
43. Tanaka, M., Y. Onodera, Y. Uchida, K. Sato, and I. Hayakawa. 1997. Inhibitory activities of quinolones against DNA gyrase and topoisomerase IV purified from Staphylococcus aureus. Antimicrob. Agents Chemother. 41: 2362-2366.
44. Wang, J. C. 1971. Interaction between DNA and an Escherichia coli protein omega. J. Mol. Biol. 55:523-533.
45. Yamagishi, J., H. Yoshida, M. Yamayoshi, and S. Nakamura. 1986. Nalidixic acid-resistant mutations of the gyrB gene of Escherichia coli. Mol. Gen. Genet. 204:367-373.
46. Yonezawa, M., M. Takahata, N. Matsubara, Y. Watanabe, and H. Narita. 1995. DNA gyrase gyrA mutations in quinolone-resistant clinical isolates of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 39:1970-1972.
47. Yoshida, H., M. Bogaki, M. Nakamura, and S. Nakamura. 1990. Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli. Antimicrob. Agents Chemother. 34:1271-1272.
48. Yoshida, H., M. Nakamura, M. Bogaki, and S. Nakamura. 1990. Proportion of DNA gyrase mutants among quinolone-resistant strains of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 34:1273-1275.
49. Yoshida, T., T. Muratani, S. Iyobe, and S. Mitsuhashi. 1994. Mechanisms of high-level resistance to quinolones in urinary tract isolates of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 38:1466-1469.