Transforming growth factor β1-regulated cell proliferation and expression of neural cell adhesion molecule in B104 neuroblastoma cells: Differential effects of ethanol

Journal of Neurochemistry

Volumn 72, Issue 6, 1999, Pages 2286-2293

  Luo, Jia ^a   Miller, Michael W ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Alcohol; Cell adhesion molecules; Cell death; Cell migration; Extracellular signal related kinase; Fetal alcohol syndrome; Signal transduction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALCOHOL; BASIC FIBROBLAST GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; GROWTH INHIBITION; NERVOUS SYSTEM DEVELOPMENT; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BLOCKING; RECEPTOR UPREGULATION;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITORS; ETHANOL; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; KINETICS; NEURAL CELL ADHESION MOLECULES; NEUROBLASTOMA; PROTEIN-SERINE-THREONINE KINASES; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 0033013897     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0722286.x     Document Type: Article

References (59)

1. Ackley R. L., Madison R. D., Archibald S. J., and Hemperly J. J. (1997) Monoclonal antibody interaction with the third immunoglobulin-like domain of N-CAM is sufficient to cause cell migration. Mol. Cell. Neurosci. 10, 117-129.
2. Adickes E. D., Mollner T. J., and Lockwood S. K. (1988) Closed chamber system for delivery of ethanol to cell cultures. Alcohol Alcohol. 23, 377-381.
3. Alessi D. R., Cuenda A., Cohen O., Dudley D. T., and Saltiel A. R. (1995) PD98059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270, 27489-27494.
4. Bartsch U., Kirchhoff F., and Schachner M. (1990) Highly sialylated N-CAM is expressed in adult mouse optic nerve and retina. J. Neurocytol. 19, 550-565.
5. Borges S. and Lewis P. D. (1983) Effects of ethanol on postnatal cell acquisition in the rat cerebellum. Brain Res. 271, 388-391.
6. Bottenstein J. E. and Sato G. H. (1979) Growth of a rat neuroblastoma cell line in serum-free supplemented medium. Proc. Natl. Acad. Sci. USA 76, 514-517.
7. Bradford M. M. (1976) A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
8. Charness M. E., Safran R. M., and Perides G. (1994) Ethanol inhibits neural cell-cell adhesion. J. Biol. Chem. 269, 9304-9309.
9. Clarren S. K. and Alvord E. C. (1976) Leptomeningeal neuroglial heterotopias in infants of alcoholic mothers. J. Neuropathol. Exp. Neurol. 35, 372.
10. Clarren S. K., Alvord E. C., Sumi S. M., Steissguth A. P., and Smith D. W. (1978) Brain malformations related to prenatal exposure to ethanol. J. Pediatr. 92, 64-67.
11. Edelman G. M. (1986) Cell adhesion molecules in neural histogenesis. Annu. Rev. Physiol. 48, 417-430.
12. Guerri C., Sàez R., Sancho-Tello M., and Renau-Piqueras J. (1990) Ethanol alters astrocyte development: a study of critical periods using primary cultures. Neurochem. Res. 15, 559-565.
13. mapk in proliferating cultures of epithelial cells. J. Biol. Chem. 270, 7117-7124.
14. Hartsough M. and Mulder K. (1997) Transforming growth factor β signaling in epithelial cells. Pharmacol. Ther. 75, 21-41.
15. Hu H., Tomasiewicz H., Magnuson T., and Rutishauser U. (1996) The role of polysialic acid in migration of olfactory bulb interneuron precursors in the subventricular zone. Neuron 16, 735-743.
16. Jones K. L. (1975) Aberrant neuronal migration in the fetal alcohol syndrome, in Birth Defects: Original Article Series, Vol. XI (Bergsma D., ed), pp. 131-132. Liss, New York.
17. Kennedy L. A. and Elliott M. J. (1985) Cell proliferation in the embryonic mouse neocortex following acute maternal alcohol intoxication. Int. J. Dev. Neurosci. 3, 311-315.
18. Kolodziejczyk S. and Hall B. K. (1996) Signal transduction and TGF-β superfamily receptors. Biochem. Cell. Biol. 74, 299-314.
19. Lavoie J. N., Rivard N., L'Allemain G., and Pouyssegur J. (1996) A temporal and biochemical link between growth factor-activated MAP kinases, cyclin D1 induction and cell cycle entry. Prog. Cell Cycle Res. 2, 49-58.
20. Liesi P. (1997) Ethanol-exposed central neurons fail to migrate and undergo apoptosis. J. Neurosci. Res. 48, 439-448.
21. Linnemann D. and Bock E. (1989) Cell adhesion molecules in neural development. Dev. Neurosci. 11, 149-173.
22. Luo J. and Miller M. W. (1996) Ethanol inhibits basic fibroblast growth factor-mediated proliferation of C6 astrocytoma cells. J. Neurochem. 67, 1448-1456.
23. Luo J. and Miller M. W. (1997a) Differential sensitivity of human neuroblastoma cell lines to ethanol: correlations with their proliferative responses to mitogenic growth factors and expression of growth factor receptors. Alcohol. Clin. Exp. Res. 21, 1186-1194.
24. Luo J. and Miller M. W. (1997b) Basic fibroblast growth factor-and platelet-derived growth factor-mediated cell proliferation in B104 neuroblastoma cells: effect of ethanol on cell cycle kinetics. Brain Res. 770, 139-150.
25. Luo J. and Miller M. W. (1998) Growth factor-mediated neural proliferation: target of ethanol toxicity. Brain Res. Rev. 27, 157-167.
26. Marshall C. J. (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185.
27. Miller M. W. (1986) Effects of alcohol on the generation and migration of cerebral cortical neurons. Science 233, 1308-1311.
28. Miller M. W. (1988) Effect of prenatal exposure to ethanol on the development of cerebral cortex: I. Neuronal generation. Alcohol. Clin. Exp. Res. 12, 440-449.
29. Miller M. W. (1992) Effects of prenatal exposure to ethanol on cell proliferation and neuronal migration, in Development of the Central Nervous System: Effects of Alcohol and Opiates (Miller M. W., ed), pp. 47-69. Liss, New York.
30. Miller M. W. (1993) Migration of cortical neurons is altered by gestational exposure to ethanol. Alcohol. Clin. Exp. Res. 21, 1186-1194.
31. Miller M. W. (1995) Generation of neurons in the rat dentate gyrus and hippocampus: effects of prenatal and postnatal treatment with ethanol. Alcohol. Clin. Exp. Res. 19, 1500-1509.
32. Miller M. W. (1997) Effects of prenatal exposure to ethanol on callosal projection neurons in rat somatosensory cortex. Brain Res. 766, 121-128.
33. Miller M. W. and Guerri C. (1996) Supporting cells as targets of ethanol toxicity: altered regulation of growth factors and extracellular matrix. Alcohol. Clin. Exp. Res. 20, 260A-264A.
34. Miller M. W. and Kuhn P. E. (1995) Cell cycle kinetics in fetal rat cerebral cortex: effects of prenatal exposure to ethanol assessed by a cumulative labeling technique with flow cytometry. Alcohol. Clin. Exp. Res. 19, 233-237.
35. Miller M. W. and Nowakowski R. S. (1991) Effect of prenatal exposure to ethanol on the cell cycle kinetics and growth fraction in the proliferative zones of the fetal rat cerebral cortex. Alcohol. Clin. Exp. Res. 15, 229-232.
36. Miller M. W. and Robertson S. (1993) Prenatal exposure to ethanol alters the postnatal development and transformation of radial glia to astrocytes in rat somatosensory cortex. J. Comp. Neurol. 337, 253-266.
37. Mucsi I., Skorecki K. L., and Goldberg H. J. (1996) Extracellular signal-regulated kinase and the small GTP-binding protein. Rac, contribute to the effects of transforming growth factor-β1 on gene expression. J. Biol. Chem. 271, 16567-16572.
38. Nishida E. and Gotoh Y. (1993) The MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem. Sci. 18, 128-131.
39. Pantazis N. J., Dohrman D. P., Luo J., Goodlett C. R., and West J. R. (1992) Ethanol reduces the number of pheochromocytoma (PC12) cells in culture. Alcohol 9, 171-180.
40. Peiffer J., Majewski F., Fischbach H., Bierich J. R., and Volk B. (1979) Alcohol embryo-and fetopathy: neuropathology of 3 children and 3 fetuses. J. Neurol. Sci. 41, 125-137.
41. Pelech S. L. and Charest D. L. (1995) MAP kinase-dependent pathways in cell cycle control. Prog. Cell Cycle Res. 1, 33-52.
42. Pentney R. J. and Miller M. W. (1992) Effects of ethanol on neuronal morphogenesis, in Development of the Central Nervous System: Effects of Alcohol and Opiates (Miller M. W., ed), pp. 71-107. Liss, New York.
43. Pratt O. E. and Doshi R. (1984) Range of alcohol-induced damage in the developing central nervous system. Ciba Found. Symp. 105, 142-156.
44. Qiu M.-S. and Green S. H. (1992) NGF and EGF rapidly activate p21 ras in PC12 cells by distinct, convergent pathways involving tyrosine phosphorylation. Neuron 9, 705-717.
45. Ramanathan R., Wilkemeyer M. F., Mittal B., Perides G., and Charness M. E. (1996) Alcohol inhibits cell-cell adhesion mediated by human L1. J. Cell Biol. 133, 381-390.
46. Reimann T., Hempel U., Krautwald S., Axmann A., Scheibe R., Seidel D., and Wenzel K. W. (1997) Transforming growth factor beta 1 induces activation of ras, raf-1, MEK and MAPK in rat hepatic stellate cells. FEBS Lett. 403, 57-60.
47. Resnicoff M., Cui S., Coppola D., Hoek J. B., and Rubin R. (1996) Ethanol-induced inhibition of cell proliferation is modulated by insulin-like growth factor-I receptor levels. Alcohol. Clin. Exp. Res. 20, 961-966.
48. Roivainen R., Hundle B., and Messing R. O. (1995) Ethanol enhances growth factor activation of mitogen-activated protein kinases by a protein kinase C-dependent mechanism. Proc. Natl. Acad. Sci. USA 92, 1891-1895.
49. Roubin R., Deagostini-Bazín H., Hirsch M., and Goridis C. (1990) Modulation of N-CAM expression by TGFβ, serum, and autocrine factors. J. Cell Biol. 111, 673-684.
50. Rutishauser U. and Jessell T. M. (1988) Cell adhesion molecules in vertebrate neural development. Physiol. Rev. 68, 819-857.
51. Saad B., Constam D. B., Ortmann R., Moos M., Fontana A., and Schachner M. (1991) Astrocyte-derived TGFβ2 and NGF differentially regulate neural cell adhesion molecule expression by cultured astrocytes. J. Cell Biol. 115, 473-484.
52. Schubert D., Heinemann S., Carlisle W., Tarikas H., Kimes B., Patrick J., Steinbach J. H., Culp W., and Brandt B. L. (1974) Clonal cell lines from the rat central nervous system. Nature 249, 224-227.
53. Seki T. and Arai Y. (1991) Expression of highly polysialylated NCAM in the neocortex and piriform cortex of the developing and the adult rat. Anat. Embryol. (Berl.) 184, 395-401.
54. Sporn M. B. and Roberts A. B. (1992) Transforming growth factor-beta: recent progress and new challenges. J. Cell Biol. 119, 1017-1021.
55. Stewart H., Rougon G., Dong Z., Dean C., Jessen K., and Mirsky R. (1995) TGFβs upregulate N-CAM and L1 expression in cultured Schwann cells, suppress cyclic AMP-induced expression of O4 and galactocerebroside, and are widely expressed in cells of Schwann cell lineage in vivo. Glia 15, 419-436.
56. Tombes R. M., Auer K. L., Mikkelsen R., Valerie K., Wymann M. P., Marshall C. J., McMahon M., and Dent P. (1998) The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic. Biochem. J. 330, 1451-1460.
57. Wang C., Pralong W. F., Schulz M. F., Rougon G., Aubry J. M., Pagliusi S., Robert A., and Kiss J. Z. (1996) Functional N-methyl-D-aspartate receptor in O-2A glial precursor cells: a critical role in regulating polysialic acid-neural cell adhesion molecule expression and cell migration. J. Cell Biol. 135, 1565-1581.
58. Wood G. K., Tomasiewicz H., Rutishauser U., Magnuson T., Quirion R., Rochford J., and Srivastava L. K. (1998) N-CAM-180 knock-out mice display increased lateral ventricle size and reduced prepulse inhibition of startle. Neuroreport 9, 461-466.
59. Yan C. Y. and Greene L. A. (1998) Prevention of PC12 cell death by N-acetylcysteine requires activation of the ras pathway. J. Neurosci. 18, 4042-4049.