Ethanol inhibits basic fibroblast growth factor-mediated proliferation of C6 astrocytoma cells

Journal of Neurochemistry

Volumn 67, Issue 4, 1996, Pages 1448-1456

  Luo, Jia ^a   Miller, Michael W ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Alcohol; Cancer; Cell proliferation; Dose response relationship; Fetal alcohol syndrome; Glioma

Indexed keywords

ALCOHOL; BASIC FIBROBLAST GROWTH FACTOR;

ANIMAL CELL; ARTICLE; ASTROCYTOMA CELL; CANCER CELL CULTURE; CELL PROLIFERATION; CONCENTRATION RESPONSE; FETAL ALCOHOL SYNDROME; GROWTH INHIBITION; GROWTH REGULATION; NEUROTOXICITY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

ANIMALIA;

EID: 0029788775     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67041448.x     Document Type: Article

References (66)

1. Abraham J. A., Whang J. L., Tumulo A., Mergia A., Friedman J., Gospodarowicz D., and Fiddes J. C. (1986) Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J. 5, 2523-2528.
2. Adickes E. D., Mollner T., and Lockwood S. K. (1988) Closed chamber system for delivery of ethanol to cell cultures. Alcohol Alcohol. 23, 377-381.
3. Al-Rabiai S. and Miller M. W. (1989) Effects of prenatal exposure to ethanol on the ultrastructure of layer V in somatosensory cortex of mature rats. J. Neurocytol. 18, 711-729.
4. Basilico C. and Moscatelli D. (1992) The FGF family of growth factors and oncogenes. Adv. Cancer Res. 59, 115-165.
5. Benda P., Lightbody J., and Sato G. (1968) Differentiated rat glial cells strain in tissue culture, Science 161, 370-371.
6. Besnard F., Perraud F., Sensenbrenner M., and Labourdette G. (1989) Effects of acidic and basic fibroblast growth factors on proliferation and maturation of cultured rat oligodendrocytes. Int. J. Dev. Neurosci. 7, 401-409.
7. Breese C. R., D'Costa A., Ingram R. L., Lenham J., and Sonntag W. E. (1993) Long-term suppression of insulin-like growth factor-I in rat after in utero ethanol exposure: relationship to somatic growth. J. Pharmacol. Exp. Ther. 264, 448-456.
8. Burgess W. H. and Maciag T. (1989) The heparin-binding (fibroblast) growth factor family of proteins. Annu. Rev. Biochem. 58, 575-606.
9. Dalke D. D., Scorrell M. F., Casey C. A., and Tuma D. J. (1990) Chronic ethanol administration impairs receptor-mediated endo-cytosis of epidermal growth factor by rat hepatocytes. Hepatology 12, 1085-1091.
10. Davies D. L. and Cox W. E. (1991) Delayed growth and maturation of astrocytic cultures following exposure to ethanol: electron microscopic observation. Brain Res. 547, 53-61.
11. Davies D. L. and Vernadakis A. (1984) Effects of ethanol on cultured glial cells: proliferation and glutamine synthetase activity. Dev. Brain Res. 16, 27-35.
12. Davies D. L. and Vernadakis A. (1986) Responses in astrocytic C6 glioma cells to ethanol and dibutyryl cyclic AMP. Dev. Brain Res. 24, 253-260.
13. Dolbeare F., Gratzner H., Pallavicini M. G., and Gray J. W. (1983) Flow cytometric measurement of total DNA and incorporated bromodeoxyuridine. Proc. Natl. Acad. Sci. USA 80, 5573-5577.
14. Eccleston P. A. and Silberberg D. H. (1985) Fibroblast growth factor is a mitogen for oligodendrocytes in vitro. Dev. Brain Res. 21, 315-318.
15. Fletcher T. L. and Shain W. (1993) Ethanol-induced changes in astrocyte gene expression during rat central nervous system development. Alcohol. Clin. Exp. Res. 17, 993-1001.
16. Folkman J. and Klagsbrun M. (1987) Angiogenic factors. Science 235, 442-447.
17. Gensburger C., Labourdette G., and Sensenbrenner M. (1987) Brain basic fibroblast growth factor stimulates the proliferation of rat neuronal precursor cells in vivo. FEBS Lett. 217, 1-5.
18. Goodlett C. R., Leo J. T., O'Callaghan J. P., Mahoney J. C., and West J. R. (1993) Transient cortical astrogliosis induced by alcohol exposure during the neonatal brain growth spurt in rats. Dev. Brain Res. 72, 85-97.
19. Gratzner H. G. (1982) Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine. A new agent for detection of DNA replication. Science 218, 474-475.
20. Gross J. L., Morrison R. S., Eidsvoog K., Herblin W. F., Komblit P. L., and Dexter D. L. (1990) Basic fibroblast growth factor-a potential autocrine regulator of human glioma cell growth. J. Neurosci. Res. 27, 689-696.
21. Gross J. L., Herblin W. F., Dusak B. A., Czerniak P., Diamond M. D., Sun T., Eidsvoog K., Dexter D. L., and Yayon A. (1993) Effects of modulation of basic fibroblast growth factor on tumor growth in vivo. J. Natl. Cancer Inst. 85, 121-131.
22. Hatten M. E. (1990) Riding the glial monorail: a common mechanism for glial-guided neuronal migration in different regions of the developing mammalian brain. Trends Neurosci. 13, 179-184.
23. Hatten M. E., Lynch M., Rydel R. E., Sanchez J., Joseph-Silverstein J., Moscatelli D., and Rifkin D. B. (1988) In vitro neunte extension by granule neurons is dependent on astroglial-derived fibroblast growth factor. Dev. Biol. 125, 280-289.
24. Heaton M. B., Swanson D. J., Paiva M., and Walker D. W. (1992) Ethanol exposure affects trophic activity and responsiveness in chick embryo. Alcohol 9, 161-166.
25. Heaton M. B., Paiva M., Swanson D. J., and Walker D. W. (1995a) Alterations in responsiveness to ethanol and neurotrophic sub-stances in fetal septohippocampal neurons following chronic prenatal ethanol exposure. Dev. Brain Res. 85, 1-13.
26. Heaton M. B., Paiva M., Swanson D. J., and Walker D. W. (1995b) Prenatal ethanol exposure alters neurotrophic activity in the developing rat hippocampus. Neurosci. Lett. 188, 132-136.
27. Hsu S. M., Raine L., and Fanger H. (1981) Use of biotin-avidin peroxidase complex (ABC) in immunoperoxidase techniques - a comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 29, 577-580.
28. Isenberg K., Zhou X., and Moore B. W. (1992) Ethanol inhibits C6 cell growth: fetal alcohol syndrome model. Alcohol. Clin. Exp. Res. 16, 695-699.
29. Kennedy L. A. and Elliott M. J. (1985) Cell proliferation in the embryonic mouse neocortex following acute maternal alcohol intoxication. Int. J. Dev. Neurosci. 3, 311-315.
30. Kennedy L. A. and Mukerji S. (1986) Ethanol neurotoxicity. I. Direct effects on replicating astrocytes. Neurobehav. Toxicol. Teratol. 8, 11-17.
31. Kimelberg H. K. and Aschner M. (1994) Astrocytes and their functions, past and present, in Alcohol and Glial Cells (Lancaster F. E., ed), pp. 1-40. NIAAA, Bethesda, Maryland.
32. Klagsbrun M. (1989) The fibroblast growth factor family: structural and biological properties. Prog. Growth Factor Res. 1, 207-235.
33. Kuhn P. E. and Miller M. W. (1996) Developmental expression of c-neu proteins in cerebral cortex: relationship to epidermal growth factor receptor. J. Comp. Neurol. 372, 189-203.
34. 125I labeled glucagon binding as a metabolic probe. Can. J. Physiol. Pharmacol. 60, 1171-1176.
35. Loughlin S. E. and Fallon J. H. (1993) Neurotrophic Factors. Academic Press, San Diego.
36. Majewska M. D. (1988) Interaction of ethanol with the GABA receptor in the rat brain: possible involvement of endogenous steroids. Alcohol 5, 269-273.
37. Matsuda S., Saito H., and Nishiyama N. (1990) Effect of basic fibroblast growth factor on neurons cultured from various regions of postnatal rat brain. Brain Res. 520, 310-316.
38. Mauceri H. J., Unterman T., Dempsey S., Lee W., and Conway S. (1993) Effect of ethanol exposure on circulating levels of insulin-like growth factor I and II, and insulin-like growth factor binding proteins in fetal rats. Alcohol. Clin. Exp. Res. 17, 1201-1206.
39. Miller M. W. (1989) Effect of prenatal exposure to ethanol on the development of cerebral cortex: II. Cell proliferation in the ventricular and subventricular zones of the rat. J. Comp. Neurol. 287, 326-338.
40. Miller M. W. (1995) Generation of neurons in the rat dentate gyrus and hippocampus: effects of prenatal and postnatal treatment with ethanol. Alcohol. Clin. Exp. Res. 19, 1500-1509.
41. Miller M. W. (1996) Limited ethanol exposure selectively alters the proliferation of precursor cells in cerebral cortex. Alcohol. Clin. Exp. Res. 20, 1500-1509.
42. Miller M. W. and Al-Rabiai S. (1994) Effects of prenatal exposure to ethanol on the number of axons in the pyramidal tract of the rat. Alcohol. Clin. Exp. Res. 18, 346-354.
43. Miller M. W. and Kuhn P. E. (1995) Cell cycle kinetics in fetal rat cerebral cortex: effects of prenatal exposure to ethanol assessed by a cumulative labeling technique with flow cytometry. Alcohol. Clin. Exp. Res. 19, 233-237.
44. Miller M. W. and Nowakowski R. S. (1988) Use of bromodeoxyuridine-immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system. Brain Res. 457, 44-52.
45. Miller M. W. and Nowakowski R. S. (1991) Effect of prenatal exposure to ethanol on the cell cycle kinetics and growth fraction in the proliferative zones of the fetal rat cerebral cortex. Alcohol. Clin. Exp. Res. 15, 229-232.
46. Miller M. W. and Potempa G. (1990) Numbers of neurons and glia in mature rat somatosensory cortex: effects of prenatal exposure to ethanol. J. Comp. Neurol. 293, 92-102.
47. Miller M. W. and Robertson S. (1993) Prenatal exposure to ethanol alters the postnatal development and transformation of radial glia to astrocytes in rat somatosensory cortex. J. Comp. Neurol. 337, 253-266.
48. Morrison R. S., Sharma A., de Vellis J., and Bradshaw R. A. (1986) Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture. Proc. Natl. Acad. Sci. USA 83, 7537-7541.
49. Okumura N., Takimoto K., and Okada M. (1989) C6 glioma cells produce basic fibroblast growth factor that can stimulate their own proliferation. J. Biochem. (Tokyo) 106, 904-909.
50. Pantazis N. J., Dohrman D. P., Luo J., Goodlett C. R., and West J. R. (1992) Alcohol reduces the number of pheochromocytoma (PC12) cells in culture. Alcohol 9, 171-180.
51. Pettmann B., Weibel M., Sensenbrenner M., and Labourdette G. (1985) Purification of two astroglial growth factors. FEBS Lett. 189, 102-108.
52. Phillips D. E. and Krueger S. K. (1990) Effects of postnatal ethanol exposure on glial cell development in rat optic nerve. Exp. Neurol. 107, 97-105.
53. Phillips D. E., Krueger S. K., and Rydquist J. E. (1991) Short- and long-term effects of combined pre- and postnatal ethanol exposure (three trimester equivalency) on the development of myelin and axons in rat optic nerve. Int. J. Dev. Neurosci. 9, 631-647.
54. Powell P. P. and Klagsbrun M. (1993) Regulation of basic fibroblast growth factor mRNA expression in rat C6 glioma cells. Exp. Cell Res. 209, 224-230.
55. Rakic P. (1982) Early developmental events: cell lineages, acquisition of neuronal positions, and areal and laminar development. Neurosci. Res. Prog. 20, 439-451.
56. Resnicoff M., Sell C., Ambrose D., Baserga R., and Rubin R. (1993) Ethanol inhibits the autophosphorylation of the insulin-like growth factor 1 (IGF-1) receptor and the IGF-1-mediated pro-liferation of 3T3 cells. J. Biol. Chem. 268, 21777-21782.
57. Rifkin R. M., Todd W. M., Toothaber D. R., Sussman A., Trowbridge M., and Draznin B. (1983) Effect of in vivo and in vitro alcohol administration on insulin binding and glycogenesis for isolated rat hepatocytes. Ann. Nutr. Metab. 27, 313-319.
58. Rovinski B., Hosein E. A., and Lee H. (1984) Effect of maternal ethanol ingestion during pregnancy and lactation on the structure and function of postal rat liver plasma membrane. Biochem. Pharmacol. 33, 311-317.
59. Sáez R., Burgal M., Renau-Piqueras J., Marqués A., and Guerri C. (1991) Evolution of several cytoskeletal proteins of astrocytes in primary culture: effect of prenatal alcohol exposure. Neurochem. Res. 16, 737-747.
60. Snyder A. K., Singh S. P., and Ehmann S. (1992) Effects of ethanol on DNA, RNA, and protein synthesis in rat astrocyte cultures. Alcohol. Clin. Exp. Res. 16, 295-300.
61. Tomono M. and Kiss Z. (1995) Ethanol enhances the stimulatory effects of insulin and insulin-like growth factor-I on DNA synthesis in NIH 3T3 fibroblasts. Biochem. Biophys. Res. Commun. 208, 63-67.
62. Walicke P. A. (1988) Basic and acidic fibroblast growth factors have trophic effects on neurons from multiple CNS regions. J. Neurosci. 8, 2618-2627.
63. Walicke P., Cowan W., Ueno N., Baird A., and Guillemin R. (1986) Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neunte extension. Proc. Natl. Acad. Sci. USA 83, 3012-3016.
64. Weise B., Janet T., and Grothe C. (1993) Localization of bFGF and bFGF-receptor in the developing nervous system of the embryonic and newborn rat. J. Neurosci. Res. 34, 442-453.
65. Westermann R. and Unsicker K. (1990) Basic fibroblast growth factor (bFGF) and rat C6 glioma cells: regulation of expression, absence of release, and response to exogenous bFGF. Glia 3, 510-521.
66. Yayon A., Aviezer D., Safran M., Gross J. L., Heldman Y., Cabilly S., Givol D., and Katchalski-Katzir E. (1993) Isolation of peptides that inhibit binding of basic fibroblast growth factor to its receptor from a random phage-epitope library. Proc. Natl. Acad. Sci. USA 90, 10643-10647.