Inhibition of HIV-1 Tat-TAR interaction by diphenylfuran derivatives: Effects of the terminal basic side chains

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 6, 1999, Pages 1089-1096

  Gelus, Nathalie ^a   Bailly, Christian ^a   Hamy, François ^b   Klimkait, Thomas ^c   Wilson, W David ^d   Boykin, David W ^d  

^a INSERM   (France)

^b NOVARTIS PHARMA AG   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

^d GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Diphenylfuran; HIV 1; RNA recognition; TAR RNA; Tat protein

Indexed keywords

BASIC PROTEIN; DIPHENYLFURAN DERIVATIVE; FURAMIDINE; FURIMIDAZOLINE; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG ACTIVITY; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PNEUMOCYSTIS CARINII; PNEUMOCYSTIS PNEUMONIA; RNA BINDING;

AMIDINES; ANTI-HIV AGENTS; ANTIFUNGAL AGENTS; BASE SEQUENCE; BENZAMIDINES; CELL CULTURE TECHNIQUES; DNA FOOTPRINTING; FURANS; GENE PRODUCTS, TAT; HIV LONG TERMINAL REPEAT; HIV-1; IMIDAZOLES; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; RNA, VIRAL;

FICUS (ANGIOSPERM); HUMAN IMMUNODEFICIENCY VIRUS 1; PNEUMOCYSTIS CARINII;

EID: 0033013426     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00041-3     Document Type: Article

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