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Volumn 38, Issue 1, 1999, Pages 1-13

Modelling radiation-induced biological lesions: From initial energy depositions to chromosome aberrations

Author keywords

[No Author keywords available]

Indexed keywords

BIOPHYSICS; CALCULATION; CHROMOSOME ABERRATION; CHROMOSOME CONDENSATION; CHROMOSOME TRANSLOCATION; DROSOPHILA; FLUORESCENCE IN SITU HYBRIDIZATION; INTERPHASE; IONIZING RADIATION; MITOSIS; RADIATION INJURY; REVIEW; THEORY;

EID: 0033011804     PISSN: 0301634X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004110050132     Document Type: Review
Times cited : (34)

References (76)
  • 1
    • 0017252257 scopus 로고
    • Classification and relationships of induced chromosomal structural changes
    • Savage JRK (1976) Classification and relationships of induced chromosomal structural changes. J Med Gen 12:103-122
    • (1976) J Med Gen , vol.12 , pp. 103-122
    • Savage, J.R.K.1
  • 2
    • 0028151744 scopus 로고
    • FISH-'painting' patterns resulting from complex exchanges
    • Savage JRK, Simpson PJ (1994) FISH-'painting' patterns resulting from complex exchanges. Mutat Res 312:51-60
    • (1994) Mutat Res , vol.312 , pp. 51-60
    • Savage, J.R.K.1    Simpson, P.J.2
  • 5
    • 0002005835 scopus 로고
    • An analysis of X-ray induced chromosomal aberrations in Tradescantia
    • Sax K (1940) An analysis of X-ray induced chromosomal aberrations in Tradescantia. Genetics 25:41-68
    • (1940) Genetics , vol.25 , pp. 41-68
    • Sax, K.1
  • 6
    • 0016224060 scopus 로고
    • Mechanisms of chromosomal aberration production. III. Chemicals and ionizing radiation
    • Bender MA, Griggs HG, Bedford JS (1974) Mechanisms of chromosomal aberration production. III. Chemicals and ionizing radiation. Mutat Res 23:197-212
    • (1974) Mutat Res , vol.23 , pp. 197-212
    • Bender, M.A.1    Griggs, H.G.2    Bedford, J.S.3
  • 7
    • 0022403306 scopus 로고
    • Induction of chromosome aberrations by very short tracks at different stages of the cell cycles
    • Wilkinson RE, Goodhead DT, Thacker J (1985) Induction of chromosome aberrations by very short tracks at different stages of the cell cycles. Radial Protect Dosim 13:161-165
    • (1985) Radial Protect Dosim , vol.13 , pp. 161-165
    • Wilkinson, R.E.1    Goodhead, D.T.2    Thacker, J.3
  • 8
    • 0022641348 scopus 로고
    • The induction of chromosome exchange aberrations by carbon ultrasoft x-rays in V79 hamster cells
    • Thacker J, Wilkinson RE, Goodhead DT (1986) The induction of chromosome exchange aberrations by carbon ultrasoft x-rays in V79 hamster cells. Int J Radiat Biol 49:645-646
    • (1986) Int J Radiat Biol , vol.49 , pp. 645-646
    • Thacker, J.1    Wilkinson, R.E.2    Goodhead, D.T.3
  • 9
    • 0023448448 scopus 로고
    • Concerning the nature of the initial damage required for the production of radiation induced exchange aberrations
    • Brenner DJ (1987) Concerning the nature of the initial damage required for the production of radiation induced exchange aberrations. Int J Radiat Biol 52:805-809
    • (1987) Int J Radiat Biol , vol.52 , pp. 805-809
    • Brenner, D.J.1
  • 10
    • 0027180956 scopus 로고
    • Effects of radiation of different qualities on cells: Molecular mechanisms of damage and repair
    • Goodhead DT, Thacker J, Cox R (1993) Effects of radiation of different qualities on cells: molecular mechanisms of damage and repair. Int J Radiat Biol 63:534-556
    • (1993) Int J Radiat Biol , vol.63 , pp. 534-556
    • Goodhead, D.T.1    Thacker, J.2    Cox, R.3
  • 11
    • 0031853105 scopus 로고    scopus 로고
    • Effectiveness of 0.28 keV carbon K ultrasoft X-rays at producing simple and complex chromosome exchanges in human fibroblast {\it in vitro} detected using FISH
    • in press
    • Griffin CS, Hill MA, Papworth DG, Townsend KMS, Savage JRK, Goodhead DT (1998) Effectiveness of 0.28 keV carbon K ultrasoft X-rays at producing simple and complex chromosome exchanges in human fibroblast {\it in vitro} detected using FISH. Int J Radiat Biol (in press)
    • (1998) Int J Radiat Biol
    • Griffin, C.S.1    Hill, M.A.2    Papworth, D.G.3    Townsend, K.M.S.4    Savage, J.R.K.5    Goodhead, D.T.6
  • 12
    • 0025157250 scopus 로고
    • Testing the notion of the one-hit exchange
    • Cornforth MN (1990) Testing the notion of the one-hit exchange. Radiat Res 121:21-27
    • (1990) Radiat Res , vol.121 , pp. 21-27
    • Cornforth, M.N.1
  • 13
    • 0038408331 scopus 로고
    • The pairwise lesion interaction model
    • Kiefer J (ed) Springer, New York
    • Harder D (1988) The pairwise lesion interaction model. In: Kiefer J (ed) Quantitative mathematical models in radiation biology. Springer, New York, pp 159-170
    • (1988) Quantitative Mathematical Models in Radiation Biology , pp. 159-170
    • Harder, D.1
  • 14
    • 0030864297 scopus 로고    scopus 로고
    • A Monte Carlo calculation of cell inactivation by light ions
    • Ottolenghi A, Monforti F, Merzagora M (1997) A Monte Carlo calculation of cell inactivation by light ions. Int J Radiat Biol 72:505-513
    • (1997) Int J Radiat Biol , vol.72 , pp. 505-513
    • Ottolenghi, A.1    Monforti, F.2    Merzagora, M.3
  • 15
    • 0001918724 scopus 로고
    • Chromatid aberrations - The general theory
    • Wolff S (ed) Columbia University Press, New York
    • Revell SH (1963) Chromatid aberrations - the general theory. In: Wolff S (ed) Radiation induced chromosome aberrations. Columbia University Press, New York, pp 41-72
    • (1963) Radiation Induced Chromosome Aberrations , pp. 41-72
    • Revell, S.H.1
  • 16
    • 0000867748 scopus 로고
    • The breakage-and-reunion theory and the exchange theory for chromosomal aberrations induced by ionizing radiation: A short history
    • Revell SH (1974) The breakage-and-reunion theory and the exchange theory for chromosomal aberrations induced by ionizing radiation: a short history. Adv Radiat Biol 4:367-416
    • (1974) Adv Radiat Biol , vol.4 , pp. 367-416
    • Revell, S.H.1
  • 17
    • 49549144185 scopus 로고
    • The induction of chromatid deletions in accord with the breakage-and-reunion hypothesis
    • Wolff S, Bodycote J (1975) The induction of chromatid deletions in accord with the breakage-and-reunion hypothesis. Mutat Res 29:85-91
    • (1975) Mutat Res , vol.29 , pp. 85-91
    • Wolff, S.1    Bodycote, J.2
  • 18
    • 0031034212 scopus 로고    scopus 로고
    • Investigating the nature of chromatid breaks produced by restriction endonucleases
    • Harvey A, Savage J (1997) Investigating the nature of chromatid breaks produced by restriction endonucleases. Int J Radiat Biol 71:21-28
    • (1997) Int J Radiat Biol , vol.71 , pp. 21-28
    • Harvey, A.1    Savage, J.2
  • 19
    • 0000465106 scopus 로고
    • Chromosome aberrations and the theory of RBE. I. General considerations
    • Neary GJ (1965) Chromosome aberrations and the theory of RBE. I. General considerations. Int J Radiat Biol 9:477-502
    • (1965) Int J Radiat Biol , vol.9 , pp. 477-502
    • Neary, G.J.1
  • 20
    • 0030954272 scopus 로고    scopus 로고
    • Computational modelling of low-energy electron-induced DNA damage by early physical and chemical events
    • Nikjoo H, O'Neill P, Goodhead DT, Terrissol M (1997) Computational modelling of low-energy electron-induced DNA damage by early physical and chemical events. Int J Radiat Biol 71:467-483
    • (1997) Int J Radiat Biol , vol.71 , pp. 467-483
    • Nikjoo, H.1    O'Neill, P.2    Goodhead, D.T.3    Terrissol, M.4
  • 21
    • 0029616585 scopus 로고
    • The quality of DNA double-strand breaks: A Monte Carlo simulation of the end-structure of strand breaks produced by protons and alpha particles
    • Ottolenghi A, Merzagora M, Tallone L, Durante M, Paretzke HG, Wilson WE (1995) The quality of DNA double-strand breaks: a Monte Carlo simulation of the end-structure of strand breaks produced by protons and alpha particles. Radiat Environ Biophys 34:239-244
    • (1995) Radiat Environ Biophys , vol.34 , pp. 239-244
    • Ottolenghi, A.1    Merzagora, M.2    Tallone, L.3    Durante, M.4    Paretzke, H.G.5    Wilson, W.E.6
  • 22
    • 0001417380 scopus 로고    scopus 로고
    • Theoretical and experimental bases for mechanistic models of radiation-induced damage
    • O'Neill P, Goodhead DT, Menzel HG (eds) RSC. Thomas Graham House, Cambridge
    • Ottolenghi A, Merzagora M (1997) Theoretical and experimental bases for mechanistic models of radiation-induced damage. In: O'Neill P, Goodhead DT, Menzel HG (eds) Microdosimetry: an interdisciplinary approach. RSC. Thomas Graham House, Cambridge, pp 103-110
    • (1997) Microdosimetry: An Interdisciplinary Approach , pp. 103-110
    • Ottolenghi, A.1    Merzagora, M.2
  • 23
    • 0024453646 scopus 로고
    • Three-dimensional analysis of the organization of human chromosome domains in human and human-hamster hybrid interphase nuclei
    • Dekken H van, Pinkel D, Mullikin J, Trask B, Van Den Engh G, Gray J (1989) Three-dimensional analysis of the organization of human chromosome domains in human and human-hamster hybrid interphase nuclei. J Cell Sci 94:299-306
    • (1989) J Cell Sci , vol.94 , pp. 299-306
    • Van Dekken, H.1    Pinkel, D.2    Mullikin, J.3    Trask, B.4    Van Den Engh, G.5    Gray, J.6
  • 24
    • 0025101509 scopus 로고
    • Rapid metaphase and interphase detection of radiation-induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridization
    • Cremer T, Popp S, Emmerich P, Lichter P, Cremer C (1990) Rapid metaphase and interphase detection of radiation-induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridization. Cytometry 11:110-118
    • (1990) Cytometry , vol.11 , pp. 110-118
    • Cremer, T.1    Popp, S.2    Emmerich, P.3    Lichter, P.4    Cremer, C.5
  • 27
    • 0031024783 scopus 로고    scopus 로고
    • Estimation of minimal size of translocated chromosome segments detectable by fluorescence in situ hybridization
    • Kodama Y, Nakano M, Ohtaki K, Delongchamp R, Awa AA, Nakamura N (1997) Estimation of minimal size of translocated chromosome segments detectable by fluorescence in situ hybridization. Int J Radiat Biol 71:35-39
    • (1997) Int J Radiat Biol , vol.71 , pp. 35-39
    • Kodama, Y.1    Nakano, M.2    Ohtaki, K.3    Delongchamp, R.4    Awa, A.A.5    Nakamura, N.6
  • 29
    • 0030747242 scopus 로고    scopus 로고
    • DNA complex lesions induced by protons and alpha particles: Track structure characteristics determining LET-and particle-type dependence
    • Ottolenghi A, Merzagora M, Paretzke HG (1997) DNA complex lesions induced by protons and alpha particles: track structure characteristics determining LET-and particle-type dependence. Radiat Environ Biophys 36:97-103
    • (1997) Radiat Environ Biophys , vol.36 , pp. 97-103
    • Ottolenghi, A.1    Merzagora, M.2    Paretzke, H.G.3
  • 30
    • 0023886879 scopus 로고
    • On the probability of interaction between elementary radiation-induced chromosomal injuries
    • Brenner DJ (1988) On the probability of interaction between elementary radiation-induced chromosomal injuries. Radiat Environ Biophys 27:189-199
    • (1988) Radiat Environ Biophys , vol.27 , pp. 189-199
    • Brenner, D.J.1
  • 31
    • 0018145268 scopus 로고
    • A generalized formulation of dual radiation action
    • Kellerer AM, Rossi HH (1978) A generalized formulation of dual radiation action. Radiat Res 75:471-488
    • (1978) Radiat Res , vol.75 , pp. 471-488
    • Kellerer, A.M.1    Rossi, H.H.2
  • 32
    • 0022638059 scopus 로고
    • Spatial organization of chromosomes in the salivary gland nuclei of Drosophila melanogaster
    • Hochstrasser M, Mathog D, Gruenbaum Y, Saumweber H, Sedat J (1986) Spatial organization of chromosomes in the salivary gland nuclei of Drosophila melanogaster. J Cell Biol 102:112-123
    • (1986) J Cell Biol , vol.102 , pp. 112-123
    • Hochstrasser, M.1    Mathog, D.2    Gruenbaum, Y.3    Saumweber, H.4    Sedat, J.5
  • 33
    • 0014166895 scopus 로고
    • Survival, chromosome abnormalities, and recovery in heavy ion and X-irradiated mammalian cells
    • Skarsgard LD, Kihlman BA, Parker L, Pujara AM, Richardson S (1967) Survival, chromosome abnormalities, and recovery in heavy ion and X-irradiated mammalian cells. Radiat Res S7:208-221
    • (1967) Radiat Res S , vol.7 , pp. 208-221
    • Skarsgard, L.D.1    Kihlman, B.A.2    Parker, L.3    Pujara, A.M.4    Richardson, S.5
  • 34
    • 0030973250 scopus 로고    scopus 로고
    • Centric rings, acentric rings and excess acentric fragments based on a random-walk interphase chromosome model
    • Wu H-L, Durante M, Sachs RK, Yang TC (1997) Centric rings, acentric rings and excess acentric fragments based on a random-walk interphase chromosome model. Int J Radiat Biol 71:487-496
    • (1997) Int J Radiat Biol , vol.71 , pp. 487-496
    • Wu, H.-L.1    Durante, M.2    Sachs, R.K.3    Yang, T.C.4
  • 36
    • 0023252949 scopus 로고
    • A quantitative comparison of potential lethal damage repair and the rejoining of interphase chromosome breaks in low passage normal human fibroblasts
    • Cornforth MN, Bedford JS (1987) A quantitative comparison of potential lethal damage repair and the rejoining of interphase chromosome breaks in low passage normal human fibroblasts. Radiat Res 111:385-405
    • (1987) Radiat Res , vol.111 , pp. 385-405
    • Cornforth, M.N.1    Bedford, J.S.2
  • 37
    • 0029563633 scopus 로고
    • Analysis of deletions induced in the genome of mammalian cells by ionizing radiation
    • Hutchinson F (1995) Analysis of deletions induced in the genome of mammalian cells by ionizing radiation. J Mol Biol 254:372-380
    • (1995) J Mol Biol , vol.254 , pp. 372-380
    • Hutchinson, F.1
  • 38
    • 0025901088 scopus 로고
    • Parameters of the human genome
    • Morton NE (1991) Parameters of the human genome. Proc Natl Acad Sci USA 88:7474-7476
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7474-7476
    • Morton, N.E.1
  • 39
    • 0028903733 scopus 로고
    • Chromosome aberrations produced by radiation: The relationship between excess acentric fragments and dicentrics
    • Hahnfeldt P, Hlatky LR, Brenner DJ, Sachs RK (1995) Chromosome aberrations produced by radiation: the relationship between excess acentric fragments and dicentrics. Radiat Res 141:136-152
    • (1995) Radiat Res , vol.141 , pp. 136-152
    • Hahnfeldt, P.1    Hlatky, L.R.2    Brenner, D.J.3    Sachs, R.K.4
  • 40
    • 0027999976 scopus 로고
    • Modelling of DNA breaks and the formation of chromosome aberrations
    • Edwards AA, Moiseenko VV, Nikjoo H (1994) Modelling of DNA breaks and the formation of chromosome aberrations. Int J Radiat Biol 66:633-637
    • (1994) Int J Radiat Biol , vol.66 , pp. 633-637
    • Edwards, A.A.1    Moiseenko, V.V.2    Nikjoo, H.3
  • 41
    • 0029871449 scopus 로고    scopus 로고
    • On the mechanism of the formation of chromosomal aberrations by ionising radiation
    • Edwards AA, Moiseenko VV, Nikjoo H (1996) On the mechanism of the formation of chromosomal aberrations by ionising radiation. Radiat Environ Biophys 35:25-30
    • (1996) Radiat Environ Biophys , vol.35 , pp. 25-30
    • Edwards, A.A.1    Moiseenko, V.V.2    Nikjoo, H.3
  • 42
    • 0022366985 scopus 로고
    • The production of chromosome aberrations in human lymphocytes by accelerated charged particles
    • Edwards AA, Lloyd DC, Prosser JS (1985) The production of chromosome aberrations in human lymphocytes by accelerated charged particles. Radiat Prot Dosim 13:205-209
    • (1985) Radiat Prot Dosim , vol.13 , pp. 205-209
    • Edwards, A.A.1    Lloyd, D.C.2    Prosser, J.S.3
  • 43
    • 0027754153 scopus 로고
    • Cross sections for water vapour for the Monte Carlo electron track structure code from 10 eV to the MeV region
    • Uehara S, Nikjoo H, Goodhead DT (1993) Cross sections for water vapour for the Monte Carlo electron track structure code from 10 eV to the MeV region. Phys Med Biol 38:1841-1858
    • (1993) Phys Med Biol , vol.38 , pp. 1841-1858
    • Uehara, S.1    Nikjoo, H.2    Goodhead, D.T.3
  • 44
    • 0025282247 scopus 로고
    • The yield of DNA double-strand breaks produced intracellularly by ionising radiation: A review
    • Ward JF (1990) The yield of DNA double-strand breaks produced intracellularly by ionising radiation: a review. Int J Radiat Biol 57:1141-1150
    • (1990) Int J Radiat Biol , vol.57 , pp. 1141-1150
    • Ward, J.F.1
  • 45
    • 0031038613 scopus 로고    scopus 로고
    • The influence of track structure on the understanding of relative biological effectiveness for induction of chromosomal exchanges in human lymphocytes
    • Moiseenko VV, Edwards AA, Nikjoo H, Prestwich WV (1997) The influence of track structure on the understanding of relative biological effectiveness for induction of chromosomal exchanges in human lymphocytes. Radiat Res 147:208-214
    • (1997) Radiat Res , vol.147 , pp. 208-214
    • Moiseenko, V.V.1    Edwards, A.A.2    Nikjoo, H.3    Prestwich, W.V.4
  • 46
    • 0029153802 scopus 로고
    • Chromosome aberrations produced by ionizing radiation: Monte carlo simulations and chromosome painting data
    • Chen AM, Lucas JN, Hill FS, Brenner DJ, Sachs RK (1995) Chromosome aberrations produced by ionizing radiation: Monte Carlo simulations and chromosome painting data. CABIOS 11:389-397
    • (1995) CABIOS , vol.11 , pp. 389-397
    • Chen, A.M.1    Lucas, J.N.2    Hill, F.S.3    Brenner, D.J.4    Sachs, R.K.5
  • 48
    • 0030780843 scopus 로고    scopus 로고
    • Computer simulation of data on chromosome aberrations produced by X rays or alpha particles and detected by fluorescence in situ hybridization
    • Chen AM, Lucas, JN, Simpson PJ, Griffin CS, Savage JRK, Brenner DJ, Hlatky LR, Sachs RK (1997) Computer simulation of data on chromosome aberrations produced by X rays or alpha particles and detected by fluorescence in situ hybridization. Radiat Res 148:S93-S101
    • (1997) Radiat Res , vol.148
    • Chen, A.M.1    Lucas, J.N.2    Simpson, P.J.3    Griffin, C.S.4    Savage, J.R.K.5    Brenner, D.J.6    Hlatky, L.R.7    Sachs, R.K.8
  • 49
    • 0030292802 scopus 로고    scopus 로고
    • Insight into sites
    • Savage JRK (1996) Insight into sites. Mutat Res 366:81-95
    • (1996) Mutat Res , vol.366 , pp. 81-95
    • Savage, J.R.K.1
  • 50
    • 0028922207 scopus 로고
    • Estimating the true frequency of X-ray-induced complex chromosome exchanges using fluorescence in situ hybridization
    • Simpson PJ, Savage JRK (1995) Estimating the true frequency of X-ray-induced complex chromosome exchanges using fluorescence in situ hybridization. Int J Radiat Biol 67:37-45
    • (1995) Int J Radiat Biol , vol.67 , pp. 37-45
    • Simpson, P.J.1    Savage, J.R.K.2
  • 51
    • 0029060504 scopus 로고
    • Frequencies of complex chromosome exchange aberrations induced by Pu-238 α-particles and detected by fluorescence in situ hybridization using single chromosome-specific probes
    • Griffin C, Marsden SJ, Stevens DL, Simpson P, Savage JRK (1995) Frequencies of complex chromosome exchange aberrations induced by Pu-238 α-particles and detected by fluorescence in situ hybridization using single chromosome-specific probes. Int J Radiat Biol 67:431-439
    • (1995) Int J Radiat Biol , vol.67 , pp. 431-439
    • Griffin, C.1    Marsden, S.J.2    Stevens, D.L.3    Simpson, P.4    Savage, J.R.K.5
  • 53
    • 0024369699 scopus 로고
    • Calculation of initial yields of single-and double-strand breaks in cell nuclei from electrons, protons and alpha particles
    • Charlton DE, Nikjoo H, Humm JL (1989) Calculation of initial yields of single-and double-strand breaks in cell nuclei from electrons, protons and alpha particles. Int J Radiat Biol 56:1-19
    • (1989) Int J Radiat Biol , vol.56 , pp. 1-19
    • Charlton, D.E.1    Nikjoo, H.2    Humm, J.L.3
  • 54
    • 0029940191 scopus 로고    scopus 로고
    • Rejoining and misrejoining of radiation-induced chromatin breaks. I. Experiments with human lymphocytes
    • Durante M, George K, Wu H, Yang TC (1996) Rejoining and misrejoining of radiation-induced chromatin breaks. I. Experiments with human lymphocytes. Radiat Res 145:274-280
    • (1996) Radiat Res , vol.145 , pp. 274-280
    • Durante, M.1    George, K.2    Wu, H.3    Yang, T.C.4
  • 55
    • 0018903841 scopus 로고
    • The induction of chromosome aberrations in human lymphocytes by in vitro irradiation with a-particles from plutonium-239
    • Purrot RJ, Edwards AA, Lloyd DC, Stather JW (1980) The induction of chromosome aberrations in human lymphocytes by in vitro irradiation with a-particles from plutonium-239. Int J Radiat Biol 38:277-284
    • (1980) Int J Radiat Biol , vol.38 , pp. 277-284
    • Purrot, R.J.1    Edwards, A.A.2    Lloyd, D.C.3    Stather, J.W.4
  • 56
    • 0029812821 scopus 로고    scopus 로고
    • Analysis of chromosome aberrations in human peripheral lymphocytes induced by in vitro a-particle irradiation
    • Schmid E, Hieber L, Heinzmann U, Roos H, Kellerer AM (1996) Analysis of chromosome aberrations in human peripheral lymphocytes induced by in vitro a-particle irradiation. Radiat Environ Biophys 35:179-184
    • (1996) Radiat Environ Biophys , vol.35 , pp. 179-184
    • Schmid, E.1    Hieber, L.2    Heinzmann, U.3    Roos, H.4    Kellerer, A.M.5
  • 57
    • 0030816836 scopus 로고    scopus 로고
    • Induction of chromosome aberrations in human cells by charged particles
    • Wu H-L, Durante M, George K, Yang TC (1997) Induction of chromosome aberrations in human cells by charged particles. Radiat Res 148:S102-S107
    • (1997) Radiat Res , vol.148
    • Wu, H.-L.1    Durante, M.2    George, K.3    Yang, T.C.4
  • 58
    • 0021603137 scopus 로고
    • The dose-response relationship obtained at constant irradiation times for the induction of chromosome aberrations in human lymphocytes by cobalt-60 gamma-rays
    • Lloyd DC, Edwards AA, Prosser JS, Corp MJ (1984) The dose-response relationship obtained at constant irradiation times for the induction of chromosome aberrations in human lymphocytes by cobalt-60 gamma-rays. Radiat Environ Biophys 23:179-189
    • (1984) Radiat Environ Biophys , vol.23 , pp. 179-189
    • Lloyd, D.C.1    Edwards, A.A.2    Prosser, J.S.3    Corp, M.J.4
  • 59
    • 0023905310 scopus 로고
    • Induction of sister chromatid exchanges by d(42 Mev)-Be neutrons in unstimulated human-blood lymphocytes
    • Savage J, Holloway M (1988) Induction of sister chromatid exchanges by d(42 Mev)-Be neutrons in unstimulated human-blood lymphocytes. Br J Radiol 61:268-284
    • (1988) Br J Radiol , vol.61 , pp. 268-284
    • Savage, J.1    Holloway, M.2
  • 60
    • 0027976408 scopus 로고
    • Initial events in the cellular effects of ionizing radiations: Clustered damage in DNA
    • Goodhead DT (1994) Initial events in the cellular effects of ionizing radiations: clustered damage in DNA. Int J Radiat Biol 65:7-17
    • (1994) Int J Radiat Biol , vol.65 , pp. 7-17
    • Goodhead, D.T.1
  • 61
    • 0022312389 scopus 로고
    • Biochemistry of DNA lesions
    • Ward JF (1985) Biochemistry of DNA lesions. Radiat Res 104:S103-S111
    • (1985) Radiat Res , vol.104
    • Ward, J.F.1
  • 62
    • 0029664689 scopus 로고    scopus 로고
    • Clusters of DNA damage induced by ionizing radiation: Formation of short DNA fragments. I. Theoretical modeling
    • Holley WR, Chatterjee A (1996) Clusters of DNA damage induced by ionizing radiation: formation of short DNA fragments. I. Theoretical modeling. Radiat Res 145:188-199
    • (1996) Radiat Res , vol.145 , pp. 188-199
    • Holley, W.R.1    Chatterjee, A.2
  • 63
    • 0027138856 scopus 로고
    • Effect of LET on chromosomal aberration yields. I. Do long-lived, exchange-prone double strand breaks play a role?
    • Sachs RK, Brenner DJ (1993) Effect of LET on chromosomal aberration yields. I. Do long-lived, exchange-prone double strand breaks play a role? Int J Radiat Biol 64:677-688
    • (1993) Int J Radiat Biol , vol.64 , pp. 677-688
    • Sachs, R.K.1    Brenner, D.J.2
  • 64
    • 0026737923 scopus 로고
    • Estimating genomic distance from DNA sequence location in cell nuclei by a random walk model
    • Van den Engh G, Sachs R, Trask B (1992) Estimating genomic distance from DNA sequence location in cell nuclei by a random walk model. Science 257:1410-1413
    • (1992) Science , vol.257 , pp. 1410-1413
    • Van Den Engh, G.1    Sachs, R.2    Trask, B.3
  • 68
    • 0031851334 scopus 로고    scopus 로고
    • Detection of incomplete exchanges and interstitial fragments in X-irradiated human lymphocytes using a telomeric PNA probe
    • Boei J, Vermeulen S, Fomina J, Natarajan A (1998) Detection of incomplete exchanges and interstitial fragments in X-irradiated human lymphocytes using a telomeric PNA probe. Int J Radiat Biol 73:599-603
    • (1998) Int J Radiat Biol , vol.73 , pp. 599-603
    • Boei, J.1    Vermeulen, S.2    Fomina, J.3    Natarajan, A.4
  • 70
    • 0342360263 scopus 로고    scopus 로고
    • Biophysical simulation of DNA fragments from low-LET radiation
    • Friedland W, Jacob P, Paretzke HG (1997) Biophysical simulation of DNA fragments from low-LET radiation. Radiat Res 148:486-487
    • (1997) Radiat Res , vol.148 , pp. 486-487
    • Friedland, W.1    Jacob, P.2    Paretzke, H.G.3
  • 71
    • 0031854165 scopus 로고    scopus 로고
    • Monte Carlo simulation of the production of short DNA fragments by low linear energy transfer radiation using higher order DNA models
    • Friedland W, Jacob P, Paretzke HG, Stork T (1998) Monte Carlo simulation of the production of short DNA fragments by low linear energy transfer radiation using higher order DNA models. Radiat Res 150:170-182
    • (1998) Radiat Res , vol.150 , pp. 170-182
    • Friedland, W.1    Jacob, P.2    Paretzke, H.G.3    Stork, T.4
  • 74
    • 0000191506 scopus 로고    scopus 로고
    • Influence of the initial spatial distribution of radical species in irradiated water on their subsequent diffusion, reactions and attack on DNA
    • Merzagora M, Friedland W, Jacob P, Monforti F, Ottolenghi A, Paretzke HG (1997) Influence of the initial spatial distribution of radical species in irradiated water on their subsequent diffusion, reactions and attack on DNA. Radiat Res 148:488-489
    • (1997) Radiat Res , vol.148 , pp. 488-489
    • Merzagora, M.1    Friedland, W.2    Jacob, P.3    Monforti, F.4    Ottolenghi, A.5    Paretzke, H.G.6
  • 75
    • 0030023098 scopus 로고    scopus 로고
    • Clusters of DNA damage induced by ionizing radiation: Formation of short DNA fragments. II. Experimental detection
    • Rydberg B (1996) Clusters of DNA damage induced by ionizing radiation: formation of short DNA fragments. II. Experimental detection. Radiat Res 145:200-209
    • (1996) Radiat Res , vol.145 , pp. 200-209
    • Rydberg, B.1
  • 76
    • 0029860006 scopus 로고    scopus 로고
    • Non-random distribution of DNA double-strand breaks induced by particle irradiation
    • Loebrich M, Cooper PK, Rydberg B (1996) Non-random distribution of DNA double-strand breaks induced by particle irradiation. Int J Radiat Biol 70:493-503
    • (1996) Int J Radiat Biol , vol.70 , pp. 493-503
    • Loebrich, M.1    Cooper, P.K.2    Rydberg, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.