Absence of CD34 on some human SCID-repopulating cells

Annals of the New York Academy of Sciences

Volumn 872, Issue , 1999, Pages 211-219

  Dick, John E ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN;

COMBINED IMMUNODEFICIENCY; CONFERENCE PAPER; HUMAN; MOUSE; NONHUMAN; SCID MOUSE;

EID: 0033002524     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb08466.x     Document Type: Conference Paper

References (30)

1. PHILLIPS, R. 1991. Hematopoietic stem cells: concepts, assays, and controversies. Sem. Immunol. 3: 337-347.
2. MORRISON, S., N. UCHIDA & I. WEISSMAN. 1995. The biology of hematopoietic stem cells. Annu. Rev. Cell Dev. Biol. 11: 35-71.
3. ORLIC, D. & D. BODINE. 1994. What defines a pluripotent hematopoietic stem cell (PHSC): will the real PHSC please stand up. Blood 84: 3991-3994.
4. KRAUSE, D.S. et al. 1996. CD34: structure, biology, and clinical utility [see comments]. Blood 87: 1-13.
5. ANDREWS, R., J. SINGER & I. BERNSTEIN. 1989. Precursors of colony-forming cells in humans can be distinguished from colony-forming cells by expression of CD33 and CD34 antigen and light scatter. J. Exp. Med. 169: 1721.
6. JONES, R.J. et al. 1996. Characterization of mouse lymphohematopoietic stem cells lacking spleen colony-forming activity. Blood 88: 487-491.
7. GOODELL, M.A. et al. 1996. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J. Exp. Med. 183: 1797-1806.
8. OSAWA, M. et al. 1996. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273: 242-245.
9. GOODELL, M. et al. 1997. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat. Med. 3: 1337-1345.
10. DICK, J.E. 1996. Normal and leukemic human stem cells assayed in SCID mice. Semin. Immunol. 8: 197-206.
11. LAPIDOT, T. et al. 1992. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice. Science 255: 1137-1141.
12. KAMEL-REID, S. & J.E. DICK. 1988. Engraftment of immune-deficient mice with human hematopoietic stem cells. Science 242: 1706-1709.
13. LAROCHELLE, A. et al. 1996. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy. Nat. Med. 2: 1329-1337.
14. BHATIA, M. et al. 1997. Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice. Proc. Natl. Acad. Sci. USA 94: 5320-5325.
15. WANG, J.C., M. DOEDENS & J.E. DICK. 1997. Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay. Blood 89: 3919-3924.
16. BHATIA, M. et al. 1997. Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture. J. Exp. Med. 186: 619-624.
17. ZANJANI, E.D. 1997. The human/sheep xenograft model for assay of human HSC (discussion). Stem Cells 15: 209.
18. + cells. Exp. Hematol. 26: 353-360.
19. BHATIA, M. et al. 1998. A newly discovered class of human hematopoietic cells with SCID-repopulating activity. Nat. Med. 4: 1038-1045.
20. BERTOLINI, F. et al. 1997. Multilineage long-term engraftment potential of drug-resistant hematopoietic progenitors. Blood 90: 3027-3036.
21. - progenitor cells. Blood 77: 1218-1227.
22. - hematopoietic stem cells. Blood 83: 1515-1526.
23. BAUM, C.M. et al. 1992. Isolation of a candidate human hematopoietic stem-cell population. Proc. Natl. Acad. Sci. USA 89: 2804-2808.
24. CRAIG, W. et al. 1993. Expression of Thy-1 on human hematopoietic progenitor cells. J. Exp. Med. 177: 1331-1342.
25. SPANGRUDE, G.-J., D.M. BROOKS & D.B. TUMAS. 1995. Long-term repopulation of irradiated mice with limiting numbers of purified hematopoietic stem cells: in vivo expansion of stem cell phenotype but not function. Blood 85: 1006-1016.
26. SUZUKI, A. et al. 1996. CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein. Blood 87: 3550-3562.
27. CHENG, J. et al. 1996. Hematopoietic defects in mice lacking the sialomucin CD34. Blood 87: 479-490.
28. LAPIDOT, T. et al. 1994. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367: 645-648.
29. BONNET, D. & J.E. DICK. 1997. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3: 730-737.
30. + peripheral blood stem cells in patients with advanced hematologic malignancy. Blood 88: 4132-4138.