Clinical significance of cyclin-dependent kinase inhibitor p27(Kip1) expression and proliferation in non-Hodgkin's lymphoma: Independent prognostic value of p27(Kip1)

British Journal of Haematology

Volumn 105, Issue 3, 1999, Pages 730-736

  Moøller, Michael B ^a   Skjoødt, Karsten ^a   Mortensen, Leif S ^b   Pedersen, Niels T ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b Danish Comp Ctr for Res and Educ   (Denmark)

Author keywords

Immunohistochemistry; Lymphoma; p27; Prognosis; Proliferation

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; KI 67 ANTIGEN; PROTEIN P27;

ADULT; AGED; ARTICLE; CELL PROLIFERATION; CORRELATION FUNCTION; DISEASE MARKER; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADULT; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; ENZYME INHIBITORS; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOMA, NON-HODGKIN; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; PROGNOSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 0033000297     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1999.01417.x     Document Type: Article

References (31)

1. Kip1 protein: prognostic implications in primary breast cancer. Nature Medicine, 3, 227-230.
2. KIP1 in multistage colorectal carcinogenesis. Cancer Research, 58, 114-122.
3. Erlanson, M., Portin, C., Linderholm, B., Lindh. J., Roos, G. & Landberg, G. (1998) Expression of cyclin E and the cyclin-dependent kinase inhibitor p27 in malignant lymphomas: prognostic implications. Blood, 92, 770-777.
4. Esposito, V., Baldi, A., De Luca, A., Groger, A.M., Loda, M., Giordano, G.G., Caputi, M., Baldi, F., Pagano, M. & Giordano, A. (1997) Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer. Cancer Research, 57, 3381-3385.
5. kip1 and degree of malignancy in human breast and colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America, 94, 6380-6385.
6. Harris, N.L.. Jaffe, E.S., Stein, H., Banks, P.M., Chan, J.K., Cleary, M.L., Delsol, G., De Wolf-Peeters, C., Falini, B., Gatter, K.C., Grogan, T.M., Isaacson, P.G., Knowles, D.M., Mason, D.Y., Müller-Hermelink, H.K., Pileri, S.A., Piris, M.A., Ralfkiær, E. & Warnke, R.A. (1994) A revised European American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood, 84, 1361-1392.
7. Kip1 accumulation during the cell cycle. Science, 271, 1861-1864.
8. Hernandez, S., Hernandez, L., Bea, S., Cazorla, M., Fernandez, P.L., Nadal, A., Muntane, J., Mallofre, C., Montserrat, E., Cardesa, A. & Campo, E. (1998) cdc25 cell cycle-activating phosphatases and c-myc expression in human non-Hodgkin's lymphomas. Cancer Research, 58, 1762-1767.
9. Hiddemann, W., Longo, D.L., Coiflier, B., Fisher, R.I., Cabanillas, F., Cavalli, F., Nadler, L.M., De Vita, V.T., Lister, T.A. & Armitage, J.O. (1996) Lymphoma classification: the gap between biology and clinical management is closing. Blood, 88, 4085-4089.
10. Kip1) of cyclin-dependent kinase 4 activation. Cell, 79, 487-496.
11. Kawamata, N., Morosetti, R., Miller, C.W., Park, D., Spirin, K.S., Nakamaki, T., Takeuchi, S., Hatta, Y., Simpson, J., Wilczynski, S., Lee, Y.Y., Bartram, C. & Koeffler, H.P. (1995) Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies. Cancer Research, 55, 2266-2269.
12. Lister, T.A., Crowther, D., Sutcliffe, S.B., Glatstein, E., Canellos, G.P., Young, R.C., Rosenberg, S.A., Coltman, C.A. & Tubiana, M. (1989) Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin's disease: Cotswolds Meeting. Journal of Clinical Oncology, 7, 1630-1636.
13. Loda, M., Cukor, B., Tam, S.W., Lavin, P., Fiorentino, M., Draetta, G.F., Jessup, J.M. & Pagano, M. (1997) Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nature Medicine, 3, 231-234.
14. Moøller, M.B., d'Amore, F. & Christensen, B.E. (1994) Testicular lymphoma: a population-based study of incidence, clinicopathological correlations and prognosis. European Journal of Cancer, 30A, 1760-1764.
15. Mori, M., Mimori, K., Shiraishi, T., Tanaka, S., Ueo, H., Sugimachi, K. & Akiyoshi, T. (1998) p27 expression and gastric carcinoma. Nature Medicine, 3, 593-593.
16. Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin. Nature, 372, 570-573.
17. KIP2 in soft tissue sarcomas and Wilms tumors. Cancer Research, 56, 1219-1221.
18. Pagano, M., Tam, S.W., Theodoras, A.M., Beer-Romero, P., Del Sal, G., Chau, V., Yew, P.R., Draetta, G. & Rolfe, M. (1995) Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science, 269, 682-685.
19. Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes and Development, 8, 9-22.
20. Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nature Medicine, 3, 222-225.
21. Kip1, a cyclin-dependent kinase inhibitor. American Journal of Pathology, 153, 175-182.
22. KIP1 expression is inversely proportional to the proliferative index. American Journal of Pathology, 151, 151-160.
23. Sherr, C.J. (1996) Cancer cell cycles. Science, 274, 1672-1677.
24. Sherr, C.J. & Roberts, J.M. (1995) Inhibitors of mammalian G1 cyclin-dependent kinases. Genes and Development, 9, 1149-1163.
25. Shiohara, M., El-Deiry, W.S., Wada, M., Nakamaki, T., Takeuchi, S., Yang, R., Chen, D.-L., Vogelstein, B. & Koeffler, H.P. (1994) Absence of WAF1 mutations in a variety of human malignancies. Blood, 84, 3781-3784.
26. Shipp, M.A., Harrington, D.P., Anderson, J.R., Armitage, J.O., Bonadonna, G., Brittinger, G., Cabanillas, F., Canellos, G.P., Coiffier, B., Connors, J.M., Cowan, R.A., Crowther, D., Dahlberg, S., Engelhard, M., Fisher, R.I., Gisselbrecht, C., Horning, S.J., Lepage, E., Lister, T.A., Meerwald, J.H., Montserrat, E., Nissen, N.I., Oken, M.M., Peterson, B.A., Tondini, C., Velasquez, W.A. & Yeap, B.Y. (1993) A predictive model for aggressive non-Hodgkin's lymphoma: the International Non-Hodgkin's Lymphoma Prognostic Factors Project. New England Journal of Medicine, 329, 987-994.
27. 1a,b) invasive breast carcinomas. Cancer Research, 57, 1259-1263.
28. Kip1 is a novel prognostic faclor in localized human prostate adenocarcinoma. Cancer Research, 58, 542-548.
29. Kip1 is abrogated by c-myc. EMBO Journal, 15, 6595-6604.
30. Kip1 in chronic B-cell lymphocytic leukemia. Blood, 91, 4694-4700.
31. KIP1 in human lung cancers: differential changes in small cell and non-small cell carcinomas. Cancer Research, 58, 1042-1047.