Synthesis and evaluation of azole-substituted 2-aryl-6-methoxy-3,4- dihydronaphthalenes and -naphthalenes as inhibitors of 17α-hydroxylase- C17,20-Lyase (P450 17)

Archiv der Pharmazie

Volumn 332, Issue 1, 1999, Pages 25-30

  Zhuang, Yan ^a   Hartmann, Rolf W ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

17 hydroxylase C17,20 lyase (P450 17; CYP 17); Azole substituted 2 aryl 3,4 dihydronaphthalenes and 2 aryl naphthalene; Nonsteroidal P450 17 inhibitors

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOCHROME P450; NAPHTHALENE DERIVATIVE; STEROID 17ALPHA MONOOXYGENASE;

ARTICLE; DRUG ACTIVITY; DRUG CONFORMATION; DRUG SYNTHESIS; ENZYME INHIBITION; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

EID: 0032995941     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4184(19991)332:1<25::AID-ARDP25>3.0.CO;2-7     Document Type: Article

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