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Volumn 55, Issue 3, 1999, Pages 778-792

Role of glutamine in human carbohydrate metabolism in kidney and other tissues

Author keywords

Amino acid; Carbon transport; Gluconeogenesis; Glycogenolysis; Hypoglycemia; Metabolic pathways

Indexed keywords

ALANINE; AMINO ACID; CARBOHYDRATE; CATECHOLAMINE; GLUCAGON; GLUTAMINE; GLYCOGEN; GROWTH HORMONE; INSULIN; PARATHYROID HORMONE; THYROXINE;

EID: 0032988976     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1999.055003778.x     Document Type: Article
Times cited : (185)

References (218)
  • 1
    • 0016703172 scopus 로고
    • Influence of postoperative state on intracellular free amino acids in human muscle tissue
    • Vinnars E, Bergström J, Fürst P: Influence of postoperative state on intracellular free amino acids in human muscle tissue. Ann Surg 182:665-671, 1975
    • (1975) Ann Surg , vol.182 , pp. 665-671
    • Vinnars, E.1    Bergström, J.2    Fürst, P.3
  • 2
  • 3
    • 0022209426 scopus 로고
    • Amino acid concentrations in plasma and skeletal muscle of patients with acute hemorrhage necrotizing pancreatitis
    • Roth E, Zoch G, Schultz F: Amino acid concentrations in plasma and skeletal muscle of patients with acute hemorrhage necrotizing pancreatitis. Clin Chem 31:1305-1309, 1985
    • (1985) Clin Chem , vol.31 , pp. 1305-1309
    • Roth, E.1    Zoch, G.2    Schultz, F.3
  • 5
    • 0028253627 scopus 로고
    • Branched-chain amino acids augment ammonia metabolism while attenuating protein breakdown during exercise
    • MacLean DA, Graham TE, Saltin B: Branched-chain amino acids augment ammonia metabolism while attenuating protein breakdown during exercise. Am J Physiol 267:E1010-E1022, 1994
    • (1994) Am J Physiol , vol.267
    • Maclean, D.A.1    Graham, T.E.2    Saltin, B.3
  • 6
    • 0025475371 scopus 로고
    • Is glutamine a conditionally essential amino acid?
    • Lacey JM, Wilmore DW: Is glutamine a conditionally essential amino acid? Nutr Rev 48:297-309, 1990
    • (1990) Nutr Rev , vol.48 , pp. 297-309
    • Lacey, J.M.1    Wilmore, D.W.2
  • 7
    • 0001685782 scopus 로고
    • Glulamine metabolism and its physiologic importance
    • Smith R: Glulamine metabolism and its physiologic importance. JPEN 14:405-445, 1990
    • (1990) JPEN , vol.14 , pp. 405-445
    • Smith, R.1
  • 8
    • 0020536675 scopus 로고
    • Mitochondrial metabolism of glutamine and glutamate and its physiological significance
    • Kovacevic Z, McGivan JD: Mitochondrial metabolism of glutamine and glutamate and its physiological significance. Physiol Rev 63:547-605, 1983
    • (1983) Physiol Rev , vol.63 , pp. 547-605
    • Kovacevic, Z.1    McGivan, J.D.2
  • 10
    • 0025914681 scopus 로고
    • Glutamine: A key substrate for the splanchnic bed
    • Souba WW: Glutamine: A key substrate for the splanchnic bed. Annu Rev Nutr 11:285-308, 1991
    • (1991) Annu Rev Nutr , vol.11 , pp. 285-308
    • Souba, W.W.1
  • 11
    • 0023605533 scopus 로고
    • Interorgan glutamine flow in metabolic acidosis
    • Welbourne TC: Interorgan glutamine flow in metabolic acidosis. Am J Physiol 253:F1069-F1076, 1987
    • (1987) Am J Physiol , vol.253
    • Welbourne, T.C.1
  • 16
    • 0027431687 scopus 로고
    • Determination of glutamine and α-ketoglutarate concentration and specific activity in plasma using high-performance liquid chromatography
    • Darmaun D, D'Amore D, Haymond M: Determination of glutamine and α-ketoglutarate concentration and specific activity in plasma using high-performance liquid chromatography. J Chromatogr 620:33-38, 1993
    • (1993) J Chromatogr , vol.620 , pp. 33-38
    • Darmaun, D.1    D'Amore, D.2    Haymond, M.3
  • 19
    • 0017282949 scopus 로고
    • Alanine and glutamine synthesis and release from skeletal muscle. I. Glycolysis and amino acid release from skeletal muscle
    • Garber AJ, Karl IE, Kipnis DM: Alanine and glutamine synthesis and release from skeletal muscle. I. Glycolysis and amino acid release from skeletal muscle. J Biochem 251:826-835, 1976
    • (1976) J Biochem , vol.251 , pp. 826-835
    • Garber, A.J.1    Karl, I.E.2    Kipnis, D.M.3
  • 20
    • 0017844378 scopus 로고
    • The origin of alanine produced in skeletal muscle
    • Chang T, Goldberg A: The origin of alanine produced in skeletal muscle. J Biol Chem 253:3677-3684, 1978
    • (1978) J Biol Chem , vol.253 , pp. 3677-3684
    • Chang, T.1    Goldberg, A.2
  • 21
    • 0018101654 scopus 로고
    • Regulation and significance of amino acid metabolism in skeletal muscle
    • Goldberg A, Chang T: Regulation and significance of amino acid metabolism in skeletal muscle. Fed Proc 37:2301-2307, 1978
    • (1978) Fed Proc , vol.37 , pp. 2301-2307
    • Goldberg, A.1    Chang, T.2
  • 22
    • 0018225348 scopus 로고
    • Fate of glutamine carbon in renal metabolism
    • Vinay P, Mapes JP, Krebs HA: Fate of glutamine carbon in renal metabolism. Am J Physiol 234:F123-F129, 1978
    • (1978) Am J Physiol , vol.234
    • Vinay, P.1    Mapes, J.P.2    Krebs, H.A.3
  • 24
  • 25
    • 0026448111 scopus 로고
    • Pathways of glycogen repletion
    • Shulman GI, Landau BR: Pathways of glycogen repletion. Physiol Rev 72:1019-1035, 1992
    • (1992) Physiol Rev , vol.72 , pp. 1019-1035
    • Shulman, G.I.1    Landau, B.R.2
  • 27
    • 0000766085 scopus 로고
    • The amino acid composition of action, myosin, tropomyosin and the meronyosins
    • Kominz Dr, Hough A, Symonds P, Laki K: The amino acid composition of action, myosin, tropomyosin and the meronyosins. Arch Biochem Biophys 50:148-159, 1954
    • (1954) Arch Biochem Biophys , vol.50 , pp. 148-159
    • Kominz, D.R.1    Hough, A.2    Symonds, P.3    Laki, K.4
  • 29
  • 30
    • 0020056518 scopus 로고
    • The disposal of an intravenously administered amino acid load across the human forearm
    • Abumrad NN, Rabin D, Wise KL, Lacy WW: The disposal of an intravenously administered amino acid load across the human forearm. Metabolism 31:463-470, 1982
    • (1982) Metabolism , vol.31 , pp. 463-470
    • Abumrad, N.N.1    Rabin, D.2    Wise, K.L.3    Lacy, W.W.4
  • 31
    • 0017722672 scopus 로고
    • Effect of intraarterial infusion of the ketoanalogue of leucine on amino acid release by forearm muscle
    • Pozefsky T, Walser M: Effect of intraarterial infusion of the ketoanalogue of leucine on amino acid release by forearm muscle. Metabolism 26:807-815, 1977
    • (1977) Metabolism , vol.26 , pp. 807-815
    • Pozefsky, T.1    Walser, M.2
  • 32
    • 0030896318 scopus 로고    scopus 로고
    • Steady state and non-steady state measurements of plasma glutamine turnover in humans
    • Kreider M, Stumvoll M, Meyer C, Overkamp D, Welle S, Gerich J: Steady state and non-steady state measurements of plasma glutamine turnover in humans. Am J Physiol 272:E621-E627, 1997
    • (1997) Am J Physiol , vol.272
    • Kreider, M.1    Stumvoll, M.2    Meyer, C.3    Overkamp, D.4    Welle, S.5    Gerich, J.6
  • 35
    • 0027993182 scopus 로고
    • Glutamine kinetics in burn patients: Comparison with hormonally induced stress in volunteers
    • Gore DC, Jahook F: Glutamine kinetics in burn patients: Comparison with hormonally induced stress in volunteers. Arch Surg 129:1318-1323, 1994
    • (1994) Arch Surg , vol.129 , pp. 1318-1323
    • Gore, D.C.1    Jahook, F.2
  • 36
    • 0026352282 scopus 로고
    • Glutamine nitrogen kinetics in insulin-dependent diabetic humans
    • Darmaun D, Rongier M, Koziet J, Robert J: Glutamine nitrogen kinetics in insulin-dependent diabetic humans. Am J Physiol 261:E713-E718, 1991
    • (1991) Am J Physiol , vol.261
    • Darmaun, D.1    Rongier, M.2    Koziet, J.3    Robert, J.4
  • 37
    • 0028223785 scopus 로고
    • Glutamine metabolism in children with short-bowel syndrome: A stable isotope study
    • Hankard R, Goulet O, Ricour C, Rongier M, Colomb V, Darmaun D: Glutamine metabolism in children with short-bowel syndrome: A stable isotope study. Pediatr Res 36:202-206, 1994
    • (1994) Pediatr Res , vol.36 , pp. 202-206
    • Hankard, R.1    Goulet, O.2    Ricour, C.3    Rongier, M.4    Colomb, V.5    Darmaun, D.6
  • 39
    • 0025334553 scopus 로고
    • Effect of epinephrine on amino acid and energy metabolism in humans
    • Matthews DE, Pesola G, Campbell RG: Effect of epinephrine on amino acid and energy metabolism in humans. Am J Physiol 258:E948-E956, 1990
    • (1990) Am J Physiol , vol.258
    • Matthews, D.E.1    Pesola, G.2    Campbell, R.G.3
  • 40
    • 0030802677 scopus 로고    scopus 로고
    • Role of glutamine as a glucose precursor in fasting humans
    • Hankard RG, Haymond MW, Darmaun D: Role of glutamine as a glucose precursor in fasting humans. Diabetes 46:1535-1541, 1997
    • (1997) Diabetes , vol.46 , pp. 1535-1541
    • Hankard, R.G.1    Haymond, M.W.2    Darmaun, D.3
  • 42
    • 0015413289 scopus 로고
    • Gluconeogenesis
    • Exton J: Gluconeogenesis. Metabolism 21:945-990, 1972
    • (1972) Metabolism , vol.21 , pp. 945-990
    • Exton, J.1
  • 44
    • 0013603174 scopus 로고
    • Gluconeogenesis and control of the blood glucose
    • edited by Murray RK, Granner DK, Mayes PA, Rodwell VW, East Norwalk, Appleton and Lange
    • Mayes PA: Gluconeogenesis and control of the blood glucose, in Harper's Biochemistry, edited by Murray RK, Granner DK, Mayes PA, Rodwell VW, East Norwalk, Appleton and Lange, 1993, p 190
    • (1993) Harper's Biochemistry , pp. 190
    • Mayes, P.A.1
  • 45
    • 0014711404 scopus 로고
    • Lactate turnover and gluconeogenesis in obesity: Effect of phenformin
    • Kreisberg R, Pennington L, Boshell B: Lactate turnover and gluconeogenesis in obesity: Effect of phenformin. Diabetes 19:64-69, 1970
    • (1970) Diabetes , vol.19 , pp. 64-69
    • Kreisberg, R.1    Pennington, L.2    Boshell, B.3
  • 46
  • 48
    • 0026518355 scopus 로고
    • Increased lipolysis and its consequences on gluconeogenesis in noninsulin-dependent diabetes mellitus
    • Nurjhan N, Consoli A, Gerich J: Increased lipolysis and its consequences on gluconeogenesis in noninsulin-dependent diabetes mellitus. J Clin Invest 89:169-175, 1992
    • (1992) J Clin Invest , vol.89 , pp. 169-175
    • Nurjhan, N.1    Consoli, A.2    Gerich, J.3
  • 49
    • 0001733433 scopus 로고
    • Renal gluconeogenesis
    • Krebs HA: Renal gluconeogenesis. Adv Enzyme Reg 1:385-400, 1963
    • (1963) Adv Enzyme Reg , vol.1 , pp. 385-400
    • Krebs, H.A.1
  • 50
    • 0025010075 scopus 로고
    • Glucose metabolism and the kidney
    • Castellino P, Defronzo RA: Glucose metabolism and the kidney. Semin Nephrol 10:458-463, 1990
    • (1990) Semin Nephrol , vol.10 , pp. 458-463
    • Castellino, P.1    Defronzo, R.A.2
  • 51
    • 0013625312 scopus 로고
    • Regulation of carbohydrate metabolism
    • edited by Satterfield T, Baltimore, Williams & Wilkins
    • Steinberg D: Regulation of carbohydrate metabolism, in Physiological Basis of Medical Practice, edited by Satterfield T, Baltimore, Williams & Wilkins, 1991, p 728
    • (1991) Physiological Basis of Medical Practice , pp. 728
    • Steinberg, D.1
  • 52
    • 0002316560 scopus 로고
    • The endocrine pancreas: Diabetes mellitus
    • edited by Felig P, Baxter JD, Frohman LA, New York, McGraw-Hill
    • Felig P, Bergman M: The endocrine pancreas: Diabetes mellitus, in Endocrinologv and Metabolism, edited by Felig P, Baxter JD, Frohman LA, New York, McGraw-Hill, 1995, p 1107
    • (1995) Endocrinologv and Metabolism , pp. 1107
    • Felig, P.1    Bergman, M.2
  • 53
    • 0019239784 scopus 로고
    • The contrasting responses of splanchnic and renal glucose output to gluconeogenic substrates and to hypoglucagonemia in 60-h-fasted humans
    • Björkman O, Felig P, Wahren J: The contrasting responses of splanchnic and renal glucose output to gluconeogenic substrates and to hypoglucagonemia in 60-h-fasted humans. Diabetes 29:610-616, 1980
    • (1980) Diabetes , vol.29 , pp. 610-616
    • Björkman, O.1    Felig, P.2    Wahren, J.3
  • 54
    • 0020029683 scopus 로고
    • Role of the kidney in the metabolism of fructose in 60-hour fasted humans
    • Björkman O, Felig P: Role of the kidney in the metabolism of fructose in 60-hour fasted humans. Diabetes 31:516-520, 1982
    • (1982) Diabetes , vol.31 , pp. 516-520
    • Björkman, O.1    Felig, P.2
  • 55
    • 0028155895 scopus 로고
    • Renal oxygen consumption, thermogenesis, and amino acid utilization during iv infusion of amino acids in man
    • Brundin T, Wahren J: Renal oxygen consumption, thermogenesis, and amino acid utilization during iv infusion of amino acids in man. Am J Physiol 267:E648-E655, 1994
    • (1994) Am J Physiol , vol.267
    • Brundin, T.1    Wahren, J.2
  • 56
    • 0029608755 scopus 로고
    • A primer on tracer methods for the study of glucose metabolism in man
    • Stumvoll M, Overkamp D, Gerich JE: A primer on tracer methods for the study of glucose metabolism in man. Diabet Nutr Metab 8:298-314, 1995
    • (1995) Diabet Nutr Metab , vol.8 , pp. 298-314
    • Stumvoll, M.1    Overkamp, D.2    Gerich, J.E.3
  • 57
    • 0022554072 scopus 로고
    • Lactate extraction during net lactate release in legs of humans during exercise
    • Stanley W, Gertz E, Wisneski J, Neese R, Morris D, Brooks G: Lactate extraction during net lactate release in legs of humans during exercise. J Appl Physiol 60:1116-1120, 1986
    • (1986) J Appl Physiol , vol.60 , pp. 1116-1120
    • Stanley, W.1    Gertz, E.2    Wisneski, J.3    Neese, R.4    Morris, D.5    Brooks, G.6
  • 58
    • 0018119238 scopus 로고
    • Renal net glucose release in vivo and its contribution to blood glucose in rats
    • Kida K, Nakago S, Kamiya F, Toyama Y, Takashi N, Nakagawa H: Renal net glucose release in vivo and its contribution to blood glucose in rats. J Clin Invest 62:721-726, 1978
    • (1978) J Clin Invest , vol.62 , pp. 721-726
    • Kida, K.1    Nakago, S.2    Kamiya, F.3    Toyama, Y.4    Takashi, N.5    Nakagawa, H.6
  • 60
    • 0028276676 scopus 로고
    • Insulin regulation of renal glucose metabolism in conscious dogs
    • Cersosimo E, Judd RL, Miles JM: Insulin regulation of renal glucose metabolism in conscious dogs. J Clin Invest 93:2584-2589, 1994
    • (1994) J Clin Invest , vol.93 , pp. 2584-2589
    • Cersosimo, E.1    Judd, R.L.2    Miles, J.M.3
  • 61
    • 0028872833 scopus 로고
    • Uptake and release of glucose by the human kidney: Postabsorptive rates and responses to epinephrine
    • Stumvoll M, Welle S, Chintalapudi U, Perriello G, Gutierrez O, Gerich J: Uptake and release of glucose by the human kidney: Postabsorptive rates and responses to epinephrine. J Clin Invest 96:2528-2533, 1995
    • (1995) J Clin Invest , vol.96 , pp. 2528-2533
    • Stumvoll, M.1    Welle, S.2    Chintalapudi, U.3    Perriello, G.4    Gutierrez, O.5    Gerich, J.6
  • 63
    • 0031720736 scopus 로고    scopus 로고
    • Effects of glucagon on renal and hepatic glutamine gluconeogenesis in normal postabsorptive humans
    • Stumvoll M, Meyer C, Kreider M, Perriello G, Gerich J: Effects of glucagon on renal and hepatic glutamine gluconeogenesis in normal postabsorptive humans. Metabolism 47:1227-1232, 1998
    • (1998) Metabolism , vol.47 , pp. 1227-1232
    • Stumvoll, M.1    Meyer, C.2    Kreider, M.3    Perriello, G.4    Gerich, J.5
  • 64
    • 0013862047 scopus 로고
    • Ultrastructural observations on renal glycogen in normal and pathologic human kidneys
    • Biava C, Grossman A, West M: Ultrastructural observations on renal glycogen in normal and pathologic human kidneys. Lab Invest 15:330-356, 1966
    • (1966) Lab Invest , vol.15 , pp. 330-356
    • Biava, C.1    Grossman, A.2    West, M.3
  • 65
    • 0021619876 scopus 로고
    • Enzyme distribution along the nephron
    • Guder WG, Ross BD: Enzyme distribution along the nephron. Kidney Int 26:101-111, 1984
    • (1984) Kidney Int , vol.26 , pp. 101-111
    • Guder, W.G.1    Ross, B.D.2
  • 66
  • 68
    • 0000619636 scopus 로고
    • The rate of gluconeogenesis from various precursors in the perfused rat liver
    • Ross BD, Hems R, Krebs HA: The rate of gluconeogenesis from various precursors in the perfused rat liver. Biochem J 102:942-951, 1967
    • (1967) Biochem J , vol.102 , pp. 942-951
    • Ross, B.D.1    Hems, R.2    Krebs, H.A.3
  • 69
    • 75449123824 scopus 로고
    • Renal gluconeogenesis the effect of diet on the gluconeogenic capacity of rat kidney cortex slices
    • Krebs HA, Bennett DAH, Degasquet P, Gascoyne T, Yoshida T: Renal gluconeogenesis the effect of diet on the gluconeogenic capacity of rat kidney cortex slices. Biochem J 86:22-28, 1963
    • (1963) Biochem J , vol.86 , pp. 22-28
    • Krebs, H.A.1    Bennett, D.A.H.2    Degasquet, P.3    Gascoyne, T.4    Yoshida, T.5
  • 70
    • 0014384993 scopus 로고
    • Glutamic acid metabolism in the lactating dairy cow
    • Egan AR, Black AL: Glutamic acid metabolism in the lactating dairy cow. J Nutr 96:450-460, 1968
    • (1968) J Nutr , vol.96 , pp. 450-460
    • Egan, A.R.1    Black, A.L.2
  • 71
    • 0015510732 scopus 로고
    • Gluconeogenesis and amino acid metabolism. I. Comparison of various precursors for hepatic gluconeogenesis in vivo
    • Aikawa T, Matsukata H, Takezawa K, Ishikawa E: Gluconeogenesis and amino acid metabolism. I. Comparison of various precursors for hepatic gluconeogenesis in vivo. Biochim Biophys Acta 279:234-244, 1972
    • (1972) Biochim Biophys Acta , vol.279 , pp. 234-244
    • Aikawa, T.1    Matsukata, H.2    Takezawa, K.3    Ishikawa, E.4
  • 72
    • 0015383623 scopus 로고
    • Gluconeogenesis from plasma amino acids in fed sheep
    • Wolff J, Bergman E: Gluconeogenesis from plasma amino acids in fed sheep. Am J Physiol 223:455-460, 1972
    • (1972) Am J Physiol , vol.223 , pp. 455-460
    • Wolff, J.1    Bergman, E.2
  • 73
    • 0017879813 scopus 로고
    • Metabolism of amino acids by the gut, liver, kidneys, and peripheral tissues
    • Bergman EN, Heitmann RN: Metabolism of amino acids by the gut, liver, kidneys, and peripheral tissues. FASEB J 37:1228-1232, 1978
    • (1978) FASEB J , vol.37 , pp. 1228-1232
    • Bergman, E.N.1    Heitmann, R.N.2
  • 74
    • 0015122017 scopus 로고
    • The effects of different dietary contents of protein on amino acid and glucose production and on the contribution of amino acids to gluconeogenesis in sheep
    • Reilly P, Ford E: The effects of different dietary contents of protein on amino acid and glucose production and on the contribution of amino acids to gluconeogenesis in sheep. Br J Nutr 26:249-263, 1971
    • (1971) Br J Nutr , vol.26 , pp. 249-263
    • Reilly, P.1    Ford, E.2
  • 75
    • 0018243689 scopus 로고
    • Glutamine metabolism, interorgan transport, and glucogenicity in the sheep
    • Heitmann RN, Bergman EN: Glutamine metabolism, interorgan transport, and glucogenicity in the sheep. Am J Physiol 234:E197-E203, 1978
    • (1978) Am J Physiol , vol.234
    • Heitmann, R.N.1    Bergman, E.N.2
  • 76
    • 0019069801 scopus 로고
    • Transport of amino acids in whole blood and plasma of sheep
    • Heitmann RN, Bergman EN: Transport of amino acids in whole blood and plasma of sheep. Am J Physiol 239:E242-E247, 1980
    • (1980) Am J Physiol , vol.239
    • Heitmann, R.N.1    Bergman, E.N.2
  • 77
    • 0015043521 scopus 로고
    • Muscle and splanchnic glutamine and glutamine metabolism in postabsorptive and starved man
    • Marliss E, Aoki T, Posefsky T, Mosh A, Cahill G: Muscle and splanchnic glutamine and glutamine metabolism in postabsorptive and starved man. J Clin Invest 50:814-817, 1971
    • (1971) J Clin Invest , vol.50 , pp. 814-817
    • Marliss, E.1    Aoki, T.2    Posefsky, T.3    Mosh, A.4    Cahill, G.5
  • 78
    • 0014094891 scopus 로고
    • Metabolic activities of the isolated perfused rat kidney
    • Nishhtsutsuji-Uwo JM, Ross BD, Krebs HA: Metabolic activities of the isolated perfused rat kidney. Biochem J 103:852-862, 1967
    • (1967) Biochem J , vol.103 , pp. 852-862
    • Nishhtsutsuji-Uwo, J.M.1    Ross, B.D.2    Krebs, H.A.3
  • 79
    • 0001903429 scopus 로고
    • Glutamine metabolism in the animal body
    • edited by Mora J, Palacios R, New York, Academic Press
    • Krebs H: Glutamine metabolism in the animal body, in Glutamine: Metabolism, Enzymology and Regulation, edited by Mora J, Palacios R, New York, Academic Press, 1980, p 319
    • (1980) Glutamine: Metabolism, Enzymology and Regulation , pp. 319
    • Krebs, H.1
  • 80
    • 0015578098 scopus 로고
    • The glucose-alanine cycle
    • Felig P: The glucose-alanine cycle. Metabolism 22:179-207, 1973
    • (1973) Metabolism , vol.22 , pp. 179-207
    • Felig, P.1
  • 81
    • 0016419551 scopus 로고
    • Amino acid metabolism in man
    • Felig P: Amino acid metabolism in man. Annu Rev Biochem 44:933-955, 1975
    • (1975) Annu Rev Biochem , vol.44 , pp. 933-955
    • Felig, P.1
  • 82
    • 0001545242 scopus 로고
    • Catabolism of proteins and of amino acid nitrogen
    • edited by Murray RK, Granner DK, Mayes PA, Rodwell VW, East Norwalk, Appleton and Lange
    • Rodwell VW: Catabolism of proteins and of amino acid nitrogen, in Harper's Biochemistry, edited by Murray RK, Granner DK, Mayes PA, Rodwell VW, East Norwalk, Appleton and Lange, 1993, p 293
    • (1993) Harper's Biochemistry , pp. 293
    • Rodwell, V.W.1
  • 87
    • 0023605591 scopus 로고
    • Determination of Krebs cycle metabolic carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall hepatic glucose output in man
    • Consol A, Kennedy F, Miles J, Gerich J: Determination of Krebs cycle metabolic carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall hepatic glucose output in man. J Clin Invest 80:1303-1310, 1987
    • (1987) J Clin Invest , vol.80 , pp. 1303-1310
    • Consol, A.1    Kennedy, F.2    Miles, J.3    Gerich, J.4
  • 88
    • 0022048405 scopus 로고
    • 14C-labeled substrates
    • 14C-labeled substrates. Am J Physiol 248:R391-R399, 1985
    • (1985) Am J Physiol , vol.248
    • Katz, J.1
  • 89
    • 0014198445 scopus 로고
    • Control of gluconeogenesis in the liver
    • Exton JH, Park CR: Control of gluconeogenesis in the liver. J Biochem 242:2622-2630, 1967
    • (1967) J Biochem , vol.242 , pp. 2622-2630
    • Exton, J.H.1    Park, C.R.2
  • 90
    • 0025181764 scopus 로고
    • Contribution of several amino acids and lactale to gluconeogenesis in hepatocytes isolated from rats fed various diets
    • Kaloyianni M, Freedland RA: Contribution of several amino acids and lactale to gluconeogenesis in hepatocytes isolated from rats fed various diets. J Nutr 120:116-122, 1990
    • (1990) J Nutr , vol.120 , pp. 116-122
    • Kaloyianni, M.1    Freedland, R.A.2
  • 91
    • 0018115066 scopus 로고
    • The effect of ammonium chloride and glucagon on the metabolism of glutamine in isolated liver cells from starved rats
    • Joseph S, McGivan J: The effect of ammonium chloride and glucagon on the metabolism of glutamine in isolated liver cells from starved rats. Biochim Biophys Acta 543:16-28, 1978
    • (1978) Biochim Biophys Acta , vol.543 , pp. 16-28
    • Joseph, S.1    McGivan, J.2
  • 92
    • 0015808262 scopus 로고
    • Regulation of renal gluconeogenesis and ammoniagenesis by physiologic fuels
    • Roxe DM, Schreiner GE, Preuss HG: Regulation of renal gluconeogenesis and ammoniagenesis by physiologic fuels. Am J Physiol 225:908-911, 1973
    • (1973) Am J Physiol , vol.225 , pp. 908-911
    • Roxe, D.M.1    Schreiner, G.E.2    Preuss, H.G.3
  • 93
    • 0019740450 scopus 로고
    • Glutamate interconversions and glucogenicity in the sheep
    • HEITMANN RN, BERGMAN EN: Glutamate interconversions and glucogenicity in the sheep. Am J Physiol 241:E465-E472, 1981
    • (1981) Am J Physiol , vol.241
    • Heitmann, R.N.1    Bergman, E.N.2
  • 94
    • 0025286236 scopus 로고
    • Gut exchange of glucose and lactate in basal state and after oral glucose ingestion in postabsorptive patients
    • Björkman O, Eriksson L, Nyberg B, Wahren J: Gut exchange of glucose and lactate in basal state and after oral glucose ingestion in postabsorptive patients. Diabetes 39:747-751, 1990
    • (1990) Diabetes , vol.39 , pp. 747-751
    • Björkman, O.1    Eriksson, L.2    Nyberg, B.3    Wahren, J.4
  • 96
    • 0017185776 scopus 로고
    • De novo synthesis of alanine by the perfused rat hindlimb
    • Grubb B: De novo synthesis of alanine by the perfused rat hindlimb. Am J Physiol 230:1379-1384, 1976
    • (1976) Am J Physiol , vol.230 , pp. 1379-1384
    • Grubb, B.1
  • 97
    • 0016286812 scopus 로고
    • The formation of glutamine and alanine in skeletal muscle
    • Ruderman N, Berger M: The formation of glutamine and alanine in skeletal muscle. J Biol Chem 249:5500-5506, 1974
    • (1974) J Biol Chem , vol.249 , pp. 5500-5506
    • Ruderman, N.1    Berger, M.2
  • 98
    • 0020421912 scopus 로고
    • Glucose and insulin effects on de novo amino acid synthesis in young men studied with stable isotope labelled alanine, glycine, leucine and lysine
    • Robert J, Bier Dm, Zhao Xh, Matthews De, Young Vr: Glucose and insulin effects on de novo amino acid synthesis in young men studied with stable isotope labelled alanine, glycine, leucine and lysine. Metabolism 31:1210-1217, 1982
    • (1982) Metabolism , vol.31 , pp. 1210-1217
    • Robert, J.1    Bier, D.M.2    Zhao, X.H.3    Matthews, D.E.4    Young, V.R.5
  • 99
    • 0014072058 scopus 로고
    • Renal metabolism of alanine
    • Pitts RF, STONE WJ: Renal metabolism of alanine. J Clin Invest 46:530-538, 1967
    • (1967) J Clin Invest , vol.46 , pp. 530-538
    • Pitts, R.F.1    Stone, W.J.2
  • 100
    • 0018137154 scopus 로고
    • Circulating alanine disposal in diabetes mellitus
    • Chochinov RH, Bowen HF, Moorhouse JA: Circulating alanine disposal in diabetes mellitus. Diabetes 27:420-426, 1978
    • (1978) Diabetes , vol.27 , pp. 420-426
    • Chochinov, R.H.1    Bowen, H.F.2    Moorhouse, J.A.3
  • 102
    • 0014691081 scopus 로고
    • Control of gluconeogenesis from amino acids in the perfused rat liver
    • Mallette LE, Exton JH, Park CR: Control of gluconeogenesis from amino acids in the perfused rat liver. J Biol Chem 244:5713-5723, 1969
    • (1969) J Biol Chem , vol.244 , pp. 5713-5723
    • Mallette, L.E.1    Exton, J.H.2    Park, C.R.3
  • 103
    • 0019380370 scopus 로고
    • The glucose-lactatc acid cycle and gluconeogenesis
    • CORI C: The glucose-lactatc acid cycle and gluconeogenesis. Curr Topics Cell Reg 18:377-387, 1981
    • (1981) Curr Topics Cell Reg , vol.18 , pp. 377-387
    • Cori, C.1
  • 104
    • 0015517384 scopus 로고
    • Glucose-lactate interrelations in man
    • Kreisberg R: Glucose-lactate interrelations in man. N Engl J Med 287:132-137, 1972
    • (1972) N Engl J Med , vol.287 , pp. 132-137
    • Kreisberg, R.1
  • 105
    • 0018088067 scopus 로고
    • The contribution of glucose to alanine metabolism in man
    • Waterhouse C, Keilson J: The contribution of glucose to alanine metabolism in man. J Lab Clin Med 92:803-812, 1978
    • (1978) J Lab Clin Med , vol.92 , pp. 803-812
    • Waterhouse, C.1    Keilson, J.2
  • 106
    • 0022379851 scopus 로고
    • Glycolytic origin of alanine formed in rat diaphragm muscle in vitro
    • Caldecourt MA, Cox DJ, Sugden MC, Palmer TN: Glycolytic origin of alanine formed in rat diaphragm muscle in vitro. Biochem J 231:801-804, 1985
    • (1985) Biochem J , vol.231 , pp. 801-804
    • Caldecourt, M.A.1    Cox, D.J.2    Sugden, M.C.3    Palmer, T.N.4
  • 107
    • 0016161237 scopus 로고
    • The effect of lysine on gluconeogenesis from lactate in rat hepatocytes
    • Cornell NW, Lund P, Krebs HA: The effect of lysine on gluconeogenesis from lactate in rat hepatocytes. Biochem J 142:327-337, 1974
    • (1974) Biochem J , vol.142 , pp. 327-337
    • Cornell, N.W.1    Lund, P.2    Krebs, H.A.3
  • 108
    • 78651132022 scopus 로고
    • Renal gluconeogenesis. II. The gluconeogenic capacity of the kidney cortex of various species
    • Krebs HA, Yoshida T: Renal gluconeogenesis. II. The gluconeogenic capacity of the kidney cortex of various species. Biochem J 89:398-400, 1963
    • (1963) Biochem J , vol.89 , pp. 398-400
    • Krebs, H.A.1    Yoshida, T.2
  • 109
    • 0018671968 scopus 로고
    • Metabolism of isolated kidney tubules: Interactions between lactate, glutamine and oleate metabolism
    • Guder WG, Wirthensohn G: Metabolism of isolated kidney tubules: Interactions between lactate, glutamine and oleate metabolism. Eur J Biochem 99:577-584, 1979
    • (1979) Eur J Biochem , vol.99 , pp. 577-584
    • Guder, W.G.1    Wirthensohn, G.2
  • 110
    • 0016686118 scopus 로고
    • Metabolic implications of the distribution of the alanine aminotransferase isoenzymes
    • Derosa G, Swick RW: Metabolic implications of the distribution of the alanine aminotransferase isoenzymes. J Biol Chem 250: 7961-7967, 1975
    • (1975) J Biol Chem , vol.250 , pp. 7961-7967
    • Derosa, G.1    Swick, R.W.2
  • 111
    • 0015860095 scopus 로고
    • Evidence of interorgan amino acid transport by blood cells in humans
    • Felig P, Wahren J, Räf L: Evidence of interorgan amino acid transport by blood cells in humans. Proc Natl Acad Sci USA 70:1775-1779, 1973
    • (1973) Proc Natl Acad Sci USA , vol.70 , pp. 1775-1779
    • Felig, P.1    Wahren, J.2    Räf, L.3
  • 113
    • 0015720588 scopus 로고
    • Inter-organal relations and roles of glutamine and alanine in the amino acid metabolism of fasted rats
    • Aikawa T, Matsutaka H, Yamamoto H, Okuda T, Ishikawa E, Kawano T, Matsumura E: Inter-organal relations and roles of glutamine and alanine in the amino acid metabolism of fasted rats. J Biochem 74:1003-1017, 1973
    • (1973) J Biochem , vol.74 , pp. 1003-1017
    • Aikawa, T.1    Matsutaka, H.2    Yamamoto, H.3    Okuda, T.4    Ishikawa, E.5    Kawano, T.6    Matsumura, E.7
  • 114
    • 0016281876 scopus 로고
    • Uptake and metabolism of plasma glutamine by the small intestine
    • Windmueller HG, Spaeth AE: Uptake and metabolism of plasma glutamine by the small intestine. J Biol Chem 249:5070-5079, 1974
    • (1974) J Biol Chem , vol.249 , pp. 5070-5079
    • Windmueller, H.G.1    Spaeth, A.E.2
  • 115
    • 0025095302 scopus 로고
    • Role of amino acid transport and countertransport in nutrition and metabolism
    • Christensen HN: Role of amino acid transport and countertransport in nutrition and metabolism. Physiol Rev 70:43-77, 1990
    • (1990) Physiol Rev , vol.70 , pp. 43-77
    • Christensen, H.N.1
  • 116
    • 0020627967 scopus 로고
    • The regulation of neutral amino acid transport in mammalian cells
    • Shotwell MA, Kilberg MS, Oxender DL: The regulation of neutral amino acid transport in mammalian cells. Biochim Biophys Acta 737:267-284, 1983
    • (1983) Biochim Biophys Acta , vol.737 , pp. 267-284
    • Shotwell, M.A.1    Kilberg, M.S.2    Oxender, D.L.3
  • 117
    • 0019301890 scopus 로고
    • Plasma-membrane transport of alanine is rate-limiting for its metabolism in rat-liver parenchymal cells
    • Sips HJ, Groen AK, Tager JM: Plasma-membrane transport of alanine is rate-limiting for its metabolism in rat-liver parenchymal cells. FEBS Lett 119:271-274, 1980
    • (1980) FEBS Lett , vol.119 , pp. 271-274
    • Sips, H.J.1    Groen, A.K.2    Tager, J.M.3
  • 118
    • 0020757614 scopus 로고
    • Concentrative uptake of alanine in hepatocytes from fed and fasted rats
    • Kristensen LO, Sestoft L, Folke M: Concentrative uptake of alanine in hepatocytes from fed and fasted rats. Am J Physiol 244:G491-G500, 1983
    • (1983) Am J Physiol , vol.244
    • Kristensen, L.O.1    Sestoft, L.2    Folke, M.3
  • 119
    • 0029099953 scopus 로고
    • Regulation of glutaminase activity and glutamine metabolism
    • Curthoys N, Watford M: Regulation of glutaminase activity and glutamine metabolism. Annu Rev Nutr 15:133-159, 1995
    • (1995) Annu Rev Nutr , vol.15 , pp. 133-159
    • Curthoys, N.1    Watford, M.2
  • 120
    • 0018217642 scopus 로고
    • The effects of ammonium chloride and bicarbonate on the activity of glutaminase in isolated liver mitochondria
    • Joseph SK, McGivan JD: The effects of ammonium chloride and bicarbonate on the activity of glutaminase in isolated liver mitochondria. Biochem J 176:837-844, 1978
    • (1978) Biochem J , vol.176 , pp. 837-844
    • Joseph, S.K.1    McGivan, J.D.2
  • 121
    • 0026520193 scopus 로고
    • Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis
    • Pilkis SJ, Granner DK: Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis. Annu Rev Physiol 54:885-909, 1992
    • (1992) Annu Rev Physiol , vol.54 , pp. 885-909
    • Pilkis, S.J.1    Granner, D.K.2
  • 122
    • 0023099179 scopus 로고
    • Mechanisms of hormonal regulation of hepatic glucose metabolism
    • Exton JH: Mechanisms of hormonal regulation of hepatic glucose metabolism. Diabetes Metab Rev 3:163-183, 1987
    • (1987) Diabetes Metab Rev , vol.3 , pp. 163-183
    • Exton, J.H.1
  • 123
    • 0020972416 scopus 로고
    • Gluconeogenesis and related aspects of glycolysis
    • Hers HG, Hue L: Gluconeogenesis and related aspects of glycolysis. Annu Rev Biochem 52:617-653, 1983
    • (1983) Annu Rev Biochem , vol.52 , pp. 617-653
    • Hers, H.G.1    Hue, L.2
  • 124
    • 0023918674 scopus 로고
    • Hormonal regulation of hepatic gluconeogenesis and glycolysis
    • Pilkis SJ, El-Maghrabi MR: Hormonal regulation of hepatic gluconeogenesis and glycolysis. Annu Rev Biochem 57:755-783, 1988
    • (1988) Annu Rev Biochem , vol.57 , pp. 755-783
    • Pilkis, S.J.1    El-Maghrabi, M.R.2
  • 125
    • 17744405359 scopus 로고
    • Dose-response characteristics for the effects of insulin on production and utilization of glucose in man
    • Rizza R, Mandarino L, Gerich J: Dose-response characteristics for the effects of insulin on production and utilization of glucose in man. Am J Physiol 240:E630-E639, 1986
    • (1986) Am J Physiol , vol.240
    • Rizza, R.1    Mandarino, L.2    Gerich, J.3
  • 126
    • 85058247423 scopus 로고    scopus 로고
    • Effects of physiological hyperinsulinemia on systemic and renal glucose, glutamine, and free fatty acid metabolism
    • Meyer C, Dostou J, Nadkarni V, Gerich J: Effects of physiological hyperinsulinemia on systemic and renal glucose, glutamine, and free fatty acid metabolism. (abstract) Diabetes 47(Suppl 1): A41, 1998
    • (1998) Diabetes , vol.47 , Issue.SUPPL. 1
    • Meyer, C.1    Dostou, J.2    Nadkarni, V.3    Gerich, J.4
  • 127
    • 0018615238 scopus 로고
    • Interrelationship of somalostatin, insulin and calcium in the control of gluconeogenesis in kidney cortex slices
    • Lupianez JA, Dileepan KN, Wagle Sr: Interrelationship of somalostatin, insulin and calcium in the control of gluconeogenesis in kidney cortex slices. Biochem Biophys Res Commun 90:1153-1158, 1979
    • (1979) Biochem Biophys Res Commun , vol.90 , pp. 1153-1158
    • Lupianez, J.A.1    Dileepan, K.N.2    Wagle, S.R.3
  • 128
    • 0016587637 scopus 로고
    • Effects of glucagon and insulin on net hepatic metabolism of glucose precursors in sheep
    • Brockman R, Bergman E, Joo P, Manns J: Effects of glucagon and insulin on net hepatic metabolism of glucose precursors in sheep. Am J Physiol 229:1344-1350, 1975
    • (1975) Am J Physiol , vol.229 , pp. 1344-1350
    • Brockman, R.1    Bergman, E.2    Joo, P.3    Manns, J.4
  • 129
    • 0016760623 scopus 로고
    • Effect of glucagon on plasma alanine and glutamine metabolism and hepatic gluconeogenesis in sheep
    • Brockman R, Bergman E: Effect of glucagon on plasma alanine and glutamine metabolism and hepatic gluconeogenesis in sheep. Am J Physiol 228:1627-1633, 1975
    • (1975) Am J Physiol , vol.228 , pp. 1627-1633
    • Brockman, R.1    Bergman, E.2
  • 130
    • 0014939327 scopus 로고
    • Gluconeogenesis in the isolated perfused rat kidney
    • Bowman RH: Gluconeogenesis in the isolated perfused rat kidney. J Biol Chem 245:1604-1612, 1970
    • (1970) J Biol Chem , vol.245 , pp. 1604-1612
    • Bowman, R.H.1
  • 131
    • 0019542316 scopus 로고
    • Sites of hormone action in the mammalian nephron
    • Morel F: Sites of hormone action in the mammalian nephron. Am J Physiol 240:F159-F164, 1981
    • (1981) Am J Physiol , vol.240
    • Morel, F.1
  • 132
    • 85058247528 scopus 로고    scopus 로고
    • Glucagon depletes circulating glutamine by increasing glutamine uptake and not affecting its release
    • Battezzati A, Simonson DC, Luzi L, Matthews DE: Glucagon depletes circulating glutamine by increasing glutamine uptake and not affecting its release. (abstract) Diabetes 45(Suppl 2):253A, 1996
    • (1996) Diabetes , vol.45 , Issue.SUPPL. 2
    • Battezzati, A.1    Simonson, D.C.2    Luzi, L.3    Matthews, D.E.4
  • 133
    • 0017704148 scopus 로고
    • The stimulatory effect of glucagon and dibutyryl AMP on ureogenesis and gluconeogenesis in relation to the mitochondrial ATP content
    • Bryla J, Harris EJ, Plumb JA: The stimulatory effect of glucagon and dibutyryl AMP on ureogenesis and gluconeogenesis in relation to the mitochondrial ATP content. FEBS Lett 80:443-448, 1977
    • (1977) FEBS Lett , vol.80 , pp. 443-448
    • Bryla, J.1    Harris, E.J.2    Plumb, J.A.3
  • 135
    • 0015607721 scopus 로고
    • Evidence for stimulation of renal gluconeogenesis by catecholamines
    • Kurokawa K, Massry SG: Evidence for stimulation of renal gluconeogenesis by catecholamines. J Clin Invest 52:961-964, 1973
    • (1973) J Clin Invest , vol.52 , pp. 961-964
    • Kurokawa, K.1    Massry, S.G.2
  • 136
    • 0020825548 scopus 로고
    • Role of gluconeogenesis in epinephrine-stimulated hepatic glucose production in humans
    • Sacca L, Vigorito C, Cicala M, Corso G, Sherwin RS: Role of gluconeogenesis in epinephrine-stimulated hepatic glucose production in humans. Am J Physiol 245:E294-E302, 1983
    • (1983) Am J Physiol , vol.245
    • Sacca, L.1    Vigorito, C.2    Cicala, M.3    Corso, G.4    Sherwin, R.S.5
  • 137
    • 85058247696 scopus 로고    scopus 로고
    • Renal glucose production during insulin-induced hypoglycemia in humans
    • Cersosimo E, Garlick P, Ferretti J: Renal glucose production during insulin-induced hypoglycemia in humans. (abstract) Diabetes 47(Suppl 1):A41, 1998
    • (1998) Diabetes , vol.47 , Issue.SUPPL. 1
    • Cersosimo, E.1    Garlick, P.2    Ferretti, J.3
  • 138
    • 85058247428 scopus 로고    scopus 로고
    • Important role of the kidney in hvpoglycemia counterregulation in humans
    • Meyer C, Dostou J, Gerich J: Important role of the kidney in hvpoglycemia counterregulation in humans. (abstract) Diabetes 47(Suppl 1):A38, 1998
    • (1998) Diabetes , vol.47 , Issue.SUPPL. 1
    • Meyer, C.1    Dostou, J.2    Gerich, J.3
  • 140
    • 0023814696 scopus 로고
    • Physiological hypercortisolemia increases proteolysis, glutaminc, and alanine production
    • Darmaun D, Matthews De, Bier DM: Physiological hypercortisolemia increases proteolysis, glutaminc, and alanine production, Am J Physiol 255:E366-E373, 1988
    • (1988) Am J Physiol , vol.255
    • Darmaun, D.1    Matthews, D.E.2    Bier, D.M.3
  • 141
    • 0001517780 scopus 로고
    • Gluconeogenesis by the human kidney
    • Aber GM, Morris LO, Housley E: Gluconeogenesis by the human kidney. Nature 212:1589-1590, 1966
    • (1966) Nature , vol.212 , pp. 1589-1590
    • Aber, G.M.1    Morris, L.O.2    Housley, E.3
  • 143
    • 0016700133 scopus 로고
    • Renal metabolic processes and acid-base changes
    • Alleyne GAO, Roobol A: Renal metabolic processes and acid-base changes. Med Clin North Am 59:781-793, 1975
    • (1975) Med Clin North Am , vol.59 , pp. 781-793
    • Alleyne, G.A.O.1    Roobol, A.2
  • 144
    • 0014515833 scopus 로고
    • Effect of acid-base status on renal and hepatic gluconeogenesis in diabetes and fasting
    • Kamm DE, Cahill GF Jr: Effect of acid-base status on renal and hepatic gluconeogenesis in diabetes and fasting. Am J Physiol 216:1207-1212, 1969
    • (1969) Am J Physiol , vol.216 , pp. 1207-1212
    • Kamm, D.E.1    Cahill G.F., Jr.2
  • 145
    • 0013900825 scopus 로고
    • Renal gluconeogenesis in acidosis, alkalosis, and potassium deficiency: Its possible role in regulation of renal ammonia production
    • Goodman AD, Fuisz RE, Cahill GF Jr: Renal gluconeogenesis in acidosis, alkalosis, and potassium deficiency: Its possible role in regulation of renal ammonia production. J Clin Invest 45:612-619, 1966
    • (1966) J Clin Invest , vol.45 , pp. 612-619
    • Goodman, A.D.1    Fuisz, R.E.2    Cahill G.F., Jr.3
  • 146
    • 0023104041 scopus 로고
    • Metabolic fate of glutamate carbon in rat renal tubules
    • Nissim I, Yudkoff M, Segal S: Metabolic fate of glutamate carbon in rat renal tubules. Biochem J 241:361-370, 1987
    • (1987) Biochem J , vol.241 , pp. 361-370
    • Nissim, I.1    Yudkoff, M.2    Segal, S.3
  • 147
    • 0028249772 scopus 로고
    • Time course of changes in mRNAs for enzymes of glutamine metabolism in kidney during metabolic acidosis
    • Schoolwerth AC, Deboer P, Moorman AF, Lamers WH: Time course of changes in mRNAs for enzymes of glutamine metabolism in kidney during metabolic acidosis. Contrib Nephrol 110: 127-132, 1994
    • (1994) Contrib Nephrol , vol.110 , pp. 127-132
    • Schoolwerth, A.C.1    Deboer, P.2    Moorman, A.F.3    Lamers, W.H.4
  • 148
    • 0002371216 scopus 로고
    • Renal glutamine metabolism and hydrogen ion homeostasis
    • edited by Häussinger D, Sies H, Berlin/ Heidelberg, Springer-Verlag
    • Welbourne TC, Phromphetcharat V: Renal glutamine metabolism and hydrogen ion homeostasis, in Glutamine Metabolism in Mammalian Tissue, edited by Häussinger D, Sies H, Berlin/ Heidelberg, Springer-Verlag, 1984, p 161
    • (1984) Glutamine Metabolism in Mammalian Tissue , pp. 161
    • Welbourne, T.C.1    Phromphetcharat, V.2
  • 149
    • 0014321032 scopus 로고
    • Relationship between glutamine utilization and production in metabolic acidosis
    • Addae SK, Lotspeich WD: Relationship between glutamine utilization and production in metabolic acidosis. Am J Physiol 215:269-277, 1968
    • (1968) Am J Physiol , vol.215 , pp. 269-277
    • Addae, S.K.1    Lotspeich, W.D.2
  • 150
    • 0020069720 scopus 로고
    • The effects of chronic metabolic acidosis on liver and muscle glutamine metabolism in the dog in vivo
    • Fine A: The effects of chronic metabolic acidosis on liver and muscle glutamine metabolism in the dog in vivo. Biochem J 202:271-273, 1982
    • (1982) Biochem J , vol.202 , pp. 271-273
    • Fine, A.1
  • 151
    • 0023196670 scopus 로고
    • Role of acidosis in regulating hepatic nitrogen metabolism during fasting in conscious dog
    • Cersosimo E, Williams P, O'Donovan D, Lacy D, Abumrad N: Role of acidosis in regulating hepatic nitrogen metabolism during fasting in conscious dog. Am J Physiol 252:E313-E319, 1987
    • (1987) Am J Physiol , vol.252
    • Cersosimo, E.1    Williams, P.2    O'Donovan, D.3    Lacy, D.4    Abumrad, N.5
  • 152
  • 153
    • 0019571082 scopus 로고
    • Interorgan relationship for glutamine metabolism in normal and acidotic rats
    • Schröck H, Goldstein L: Interorgan relationship for glutamine metabolism in normal and acidotic rats. Am J Physiol 240:E519-E525, 1981
    • (1981) Am J Physiol , vol.240
    • Schröck, H.1    Goldstein, L.2
  • 154
    • 0013575065 scopus 로고
    • Hepatic glutamine and ammonia metabolism
    • edited by Häussinger D, Sies H, Berlin/Heidelberg, Springer-Verlag
    • Sies H, Häussinger D: Hepatic glutamine and ammonia metabolism, in Glutamine Metabolism in Mammalian Tissues, edited by Häussinger D, Sies H, Berlin/Heidelberg, Springer-Verlag, 1984, p 78
    • (1984) Glutamine Metabolism in Mammalian Tissues , pp. 78
    • Sies, H.1    Häussinger, D.2
  • 155
    • 84941373846 scopus 로고
    • Renal and hepatic nitrogen metabolism in systemic acid base regulation
    • Guder WG, Häussinger D, Gerok W: Renal and hepatic nitrogen metabolism in systemic acid base regulation. J Clin Chem Clin Biochem 25:457-466, 1987
    • (1987) J Clin Chem Clin Biochem , vol.25 , pp. 457-466
    • Guder, W.G.1    Häussinger, D.2    Gerok, W.3
  • 156
    • 0020063476 scopus 로고
    • 12C atoms in the pathway of gluconeogenesis in vivo
    • 12C atoms in the pathway of gluconeogenesis in vivo. Fed Proc 41:104-109, 1982
    • (1982) Fed Proc , vol.41 , pp. 104-109
    • Hetenyi, G.1
  • 157
    • 0022454148 scopus 로고
    • Gluconeogenesis from labelled carbon: Estimating isotope dilution
    • Kelleher JK: Gluconeogenesis from labelled carbon: estimating isotope dilution. Am J Physiol 250:E296-E305, 1986
    • (1986) Am J Physiol , vol.250
    • Kelleher, J.K.1
  • 158
    • 0023479143 scopus 로고
    • Stimulation of glycogen synthesis and lipogenesis by glutamine in isolated rat hepatocytes
    • Lavoinne A, Baquet A, Hue L: Stimulation of glycogen synthesis and lipogenesis by glutamine in isolated rat hepatocytes. Biochem 7248:429-437, 1987
    • (1987) Biochem , vol.7248 , pp. 429-437
    • Lavoinne, A.1    Baquet, A.2    Hue, L.3
  • 160
    • 0025017247 scopus 로고
    • The effect of glutamine on protein turnover in chick skeletal muscle in vitro
    • Wu G, Thompson JR: The effect of glutamine on protein turnover in chick skeletal muscle in vitro. Biochem J 265:593-598, 1990
    • (1990) Biochem J , vol.265 , pp. 593-598
    • Wu, G.1    Thompson, J.R.2
  • 161
    • 0020412376 scopus 로고
    • Acceleration of proteolysis in perfused rat liver by deletion of glucogenic amino acids: Regulatory role of glutamine
    • Pösö A, Schworer C, Mortimore G: Acceleration of proteolysis in perfused rat liver by deletion of glucogenic amino acids: Regulatory role of glutamine. Biochem Biophys Res Commun 107:1433-1439, 1982
    • (1982) Biochem Biophys Res Commun , vol.107 , pp. 1433-1439
    • Pösö, A.1    Schworer, C.2    Mortimore, G.3
  • 162
    • 0018927246 scopus 로고
    • Amino acid inhibition of the autophagic/lysosomal pathway of protein degradation in isolated rat hepatocytes
    • Seglen PO, Gordon PB, Poli A: Amino acid inhibition of the autophagic/lysosomal pathway of protein degradation in isolated rat hepatocytes. Biochim Biophys Acta 630:103-118, 1980
    • (1980) Biochim Biophys Acta , vol.630 , pp. 103-118
    • Seglen, P.O.1    Gordon, P.B.2    Poli, A.3
  • 163
    • 0023720937 scopus 로고
    • Inhibition of protein breakdown by glutamine in perfused rat skeletal muscle
    • MacLennan P, Smith K, Weryk B, Watt P, Rennie M: Inhibition of protein breakdown by glutamine in perfused rat skeletal muscle. FEBS Lett 237:133-136, 1988
    • (1988) FEBS Lett , vol.237 , pp. 133-136
    • MacLennan, P.1    Smith, K.2    Weryk, B.3    Watt, P.4    Rennie, M.5
  • 164
    • 0023795075 scopus 로고
    • Relationship between glutamine concentration and protein synthesis in rat skeletal muscle
    • Jepson M, Bates P, Broadbent P, Pell J, Millward D: Relationship between glutamine concentration and protein synthesis in rat skeletal muscle. Am J Physiol 255:E166-E172, 1988
    • (1988) Am J Physiol , vol.255
    • Jepson, M.1    Bates, P.2    Broadbent, P.3    Pell, J.4    Millward, D.5
  • 167
    • 0027164528 scopus 로고
    • Dose-response effects of lactate infusions on gluconeogenesis from lactate in normal man
    • Jenssen T, Nurjhan N, Consoli A, Gerich JE: Dose-response effects of lactate infusions on gluconeogenesis from lactate in normal man. Eur J Clin Invest 23:448-454, 1993
    • (1993) Eur J Clin Invest , vol.23 , pp. 448-454
    • Jenssen, T.1    Nurjhan, N.2    Consoli, A.3    Gerich, J.E.4
  • 169
    • 0017247368 scopus 로고
    • Regulation of phosphoenolpyruvate carboxykinase by glutamine and ATP as possible control mechanisms of renal gluconeogenesis
    • Peters HH, Stumpf B, Hamm HH, Graf B, Boie-Nath A, Stiller G, Seubert W: Regulation of phosphoenolpyruvate carboxykinase by glutamine and ATP as possible control mechanisms of renal gluconeogenesis. Curr Prob Clin Biochem 6:336-345, 1976
    • (1976) Curr Prob Clin Biochem , vol.6 , pp. 336-345
    • Peters, H.H.1    Stumpf, B.2    Hamm, H.H.3    Graf, B.4    Boie-Nath, A.5    Stiller, G.6    Seubert, W.7
  • 170
    • 0022364964 scopus 로고
    • Effect of glutamine on fructose 2,6-biphosphate and on glucose metabolism in HeLa cells and in chicken-embryo fibroblasts
    • Mojena M, Bosca L, Hue L: Effect of glutamine on fructose 2,6-biphosphate and on glucose metabolism in HeLa cells and in chicken-embryo fibroblasts. Biochem J 232:521-527, 1985
    • (1985) Biochem J , vol.232 , pp. 521-527
    • Mojena, M.1    Bosca, L.2    Hue, L.3
  • 171
    • 0025370482 scopus 로고
    • Fructose-2,6-bisphosphate in control of hepatic gluconeogenesis
    • Pilkis SJ, El-Maghrabi MR, Claus TH: Fructose-2,6-bisphosphate in control of hepatic gluconeogenesis. Diabetes 13:582-599, 1990
    • (1990) Diabetes , vol.13 , pp. 582-599
    • Pilkis, S.J.1    El-Maghrabi, M.R.2    Claus, T.H.3
  • 172
    • 0016812714 scopus 로고
    • On the stimulation of gluconeogenesis by L-lysine in isolated rat kidney cortex tubules
    • Friedrichs D: On the stimulation of gluconeogenesis by L-lysine in isolated rat kidney cortex tubules. Biochim Biophys Acta 392:255-270, 1975
    • (1975) Biochim Biophys Acta , vol.392 , pp. 255-270
    • Friedrichs, D.1
  • 173
    • 0017144797 scopus 로고
    • Stimulation of hepatic glycogen synthesis by amino acids
    • Katz J, Golden S, Wals PA: Stimulation of hepatic glycogen synthesis by amino acids. Proc Natl Acad Sci USA 73:3433-3437, 1976
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 3433-3437
    • Katz, J.1    Golden, S.2    Wals, P.A.3
  • 174
    • 0018406193 scopus 로고
    • Glycogen synthesis by rat hepatocytes
    • Katz J, Golden S, Wals PA: Glycogen synthesis by rat hepatocytes. Biochem J 180:389-402, 1979
    • (1979) Biochem J , vol.180 , pp. 389-402
    • Katz, J.1    Golden, S.2    Wals, P.A.3
  • 175
    • 0022256459 scopus 로고
    • Possible role for carbamyl phosphate in the control of liver glycogen synthesis
    • Rognstad R: Possible role for carbamyl phosphate in the control of liver glycogen synthesis. Biochem Biophys Res Commun 130:229-233, 1985
    • (1985) Biochem Biophys Res Commun , vol.130 , pp. 229-233
    • Rognstad, R.1
  • 176
    • 0027056010 scopus 로고
    • Glutamine is a good substrate for glycogen synthesis in isolated hepatocytes from 72h-starved rats, but not from 24 h-or 48 h-starved rats
    • Mouterde O, Claeyssens S, Chedeville A, Lavoinne A: Glutamine is a good substrate for glycogen synthesis in isolated hepatocytes from 72h-starved rats, but not from 24 h-or 48 h-starved rats. Biochem J 288:795-799, 1992
    • (1992) Biochem J , vol.288 , pp. 795-799
    • Mouterde, O.1    Claeyssens, S.2    Chedeville, A.3    Lavoinne, A.4
  • 177
    • 0024451943 scopus 로고
    • Hepatic glycogen in humans. II. Gluconeogenetic formation after oral and intravenous glucose
    • Radziuk J: Hepatic glycogen in humans. II. Gluconeogenetic formation after oral and intravenous glucose. Am J Physiol 257:E158-E169, 1989
    • (1989) Am J Physiol , vol.257
    • Radziuk, J.1
  • 178
    • 0024451943 scopus 로고
    • Hepatic glycogen in humans. I. Direct formation after oral and intravenous glucose or after a 24-h fast
    • Radziuk J: Hepatic glycogen in humans. I. Direct formation after oral and intravenous glucose or after a 24-h fast. Am J Physiol 257:E145-E157, 1989
    • (1989) Am J Physiol , vol.257
    • Radziuk, J.1
  • 180
    • 0025307534 scopus 로고
    • Stimulation of glycogen synthesis in hepatocytes by added amino acids is related to the total intracellular content of amino acids
    • Plomp PJAM, Boon L, Caro LHP, Van Woerkom GM, Meijer AJ: Stimulation of glycogen synthesis in hepatocytes by added amino acids is related to the total intracellular content of amino acids. Eur J Biochem 191:237-243, 1990
    • (1990) Eur J Biochem , vol.191 , pp. 237-243
    • Plomp, P.J.A.M.1    Boon, L.2    Caro, L.H.P.3    Van Woerkom, G.M.4    Meijer, A.J.5
  • 181
    • 0026097836 scopus 로고
    • Comparison of the effects of various amino acids on glycogen synthesis, lipogenesis and ketogenesis in isolated rat hepatocytes
    • Baquet A, Lavoinne A, Hue L: Comparison of the effects of various amino acids on glycogen synthesis, lipogenesis and ketogenesis in isolated rat hepatocytes. Biochem J 273:57-62, 1991
    • (1991) Biochem J , vol.273 , pp. 57-62
    • Baquet, A.1    Lavoinne, A.2    Hue, L.3
  • 182
    • 0026775120 scopus 로고
    • Glyconeogenesis from L-proline involves metabolite inhibition of the glucose-6-phosphatase system
    • Bode AM, Foster JD, Nordlie RC: Glyconeogenesis from L-proline involves metabolite inhibition of the glucose-6-phosphatase system. J Biol Chem 267:2860-2863, 1992
    • (1992) J Biol Chem , vol.267 , pp. 2860-2863
    • Bode, A.M.1    Foster, J.D.2    Nordlie, R.C.3
  • 183
    • 0027257458 scopus 로고
    • Reciprocal effects of proline and glutamine on glycogenesis from glucose and ureagenesis in isolated, perfused rat livers
    • Bode A, Nordlie R: Reciprocal effects of proline and glutamine on glycogenesis from glucose and ureagenesis in isolated, perfused rat livers. J Biol Chem 268:16298-16301, 1993
    • (1993) J Biol Chem , vol.268 , pp. 16298-16301
    • Bode, A.1    Nordlie, R.2
  • 185
    • 0028821319 scopus 로고
    • Stimulatory effect of glutamine on glycogen accumulation in human skeletal muscle
    • Varnier M, Leese GP, Thompson J, Rennie MJ: Stimulatory effect of glutamine on glycogen accumulation in human skeletal muscle. Am J Physiol 269:E309-E315, 1995
    • (1995) Am J Physiol , vol.269
    • Varnier, M.1    Leese, G.P.2    Thompson, J.3    Rennie, M.J.4
  • 186
    • 0025911449 scopus 로고
    • Changes in plasma and urinary amino acid levels during diabetic ketoacidosis in children
    • Szabo A, Kenesei E, Miltenyi M, Szücs L, Nagy I: Changes in plasma and urinary amino acid levels during diabetic ketoacidosis in children. Diabetes Res Clin Pract 12:91-97, 1991
    • (1991) Diabetes Res Clin Pract , vol.12 , pp. 91-97
    • Szabo, A.1    Kenesei, E.2    Miltenyi, M.3    Szücs, L.4    Nagy, I.5
  • 187
    • 0017278690 scopus 로고
    • Effect of protein ingestion on splanchnic and leg metabolism in normal man and in patients with diabetes mellitus
    • Wahren J, Felig P, Hagenfeldt L: Effect of protein ingestion on splanchnic and leg metabolism in normal man and in patients with diabetes mellitus. J Clin Invest 57:987-999, 1976
    • (1976) J Clin Invest , vol.57 , pp. 987-999
    • Wahren, J.1    Felig, P.2    Hagenfeldt, L.3
  • 188
    • 0015788960 scopus 로고
    • Glutamine and glutamine metabolism in normal and diabetic subjects
    • Felig P, Wahren J, Karl I, Cerasi E, Luft R, Kipnis DM: Glutamine and glutamine metabolism in normal and diabetic subjects. Diabetes 22:573-576, 1973
    • (1973) Diabetes , vol.22 , pp. 573-576
    • Felig, P.1    Wahren, J.2    Karl, I.3    Cerasi, E.4    Luft, R.5    Kipnis, D.M.6
  • 189
    • 0027436656 scopus 로고
    • Different sensitivity of glucose and amino acid metabolism to insulin in NIDDM
    • Luzi L, Petrides AS, Defronzo RA: Different sensitivity of glucose and amino acid metabolism to insulin in NIDDM. Diabetes 42:1868-1877, 1993
    • (1993) Diabetes , vol.42 , pp. 1868-1877
    • Luzi, L.1    Petrides, A.S.2    Defronzo, R.A.3
  • 190
    • 0026646940 scopus 로고
    • Lipolysis and gluconeogenesis from glycerol are increased in patients with noninsulin-dependent diabetes mellitus
    • Puhakainen I, Koivisto V, Yki-Jarvinen H: Lipolysis and gluconeogenesis from glycerol are increased in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 75:789-794, 1992
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 789-794
    • Puhakainen, I.1    Koivisto, V.2    Yki-Jarvinen, H.3
  • 191
    • 0023113123 scopus 로고
    • The regulation of glutamine and ketone-body metabolism in the small intestine of the long-term (40-day) streptozotocin-diabetic rat
    • Watford M, Erbelding EJ, Smith EM: The regulation of glutamine and ketone-body metabolism in the small intestine of the long-term (40-day) streptozotocin-diabetic rat. Biochem J 242:61-68, 1987
    • (1987) Biochem J , vol.242 , pp. 61-68
    • Watford, M.1    Erbelding, E.J.2    Smith, E.M.3
  • 192
    • 0020710369 scopus 로고
    • Interorgan metabolism of amino acids in the streptozotocin-diabetic ketoacidotic rat
    • Brosnan J, Man K, Hall D, Colbourne S, Brosnan M: Interorgan metabolism of amino acids in the streptozotocin-diabetic ketoacidotic rat. Am J Physiol 244:E151-E158, 1983
    • (1983) Am J Physiol , vol.244
    • Brosnan, J.1    Man, K.2    Hall, D.3    Colbourne, S.4    Brosnan, M.5
  • 193
    • 0025630056 scopus 로고
    • Mechanism of increased gluconeogenesis in noninsulin dependent diabetes mellitus: Role of alterations in systemic, hepatic and muscle lactate and alanine metabolism
    • Consoli A, Nurjhan N, Reilly J, Bier D, Gerich J: Mechanism of increased gluconeogenesis in noninsulin dependent diabetes mellitus: Role of alterations in systemic, hepatic and muscle lactate and alanine metabolism. J Clin Invest 86:2038-2045, 1990
    • (1990) J Clin Invest , vol.86 , pp. 2038-2045
    • Consoli, A.1    Nurjhan, N.2    Reilly, J.3    Bier, D.4    Gerich, J.5
  • 194
    • 0023874590 scopus 로고
    • Glutamine and ketone body metabolism in the gut of streptozotocin-diabetic rats
    • Ardawi M: Glutamine and ketone body metabolism in the gut of streptozotocin-diabetic rats. Biochem J 249:565-572, 1988
    • (1988) Biochem J , vol.249 , pp. 565-572
    • Ardawi, M.1
  • 195
    • 0020021615 scopus 로고
    • Characteristics of ammoniagenesis and gluconeogenesis by the diabetic kidney: In vitro studies in the rat
    • Lemieux G, Achkar M, Vinay P, Gougoux A: Characteristics of ammoniagenesis and gluconeogenesis by the diabetic kidney: In vitro studies in the rat. Contrib Nephrol 31:23-28, 1982
    • (1982) Contrib Nephrol , vol.31 , pp. 23-28
    • Lemieux, G.1    Achkar, M.2    Vinay, P.3    Gougoux, A.4
  • 196
    • 0021368559 scopus 로고
    • Renal enzymes during experimental diabetes mellitus in the rat: Role of insulin, carbohydrate metabolism, and ketoacidosis
    • Lemieux G, Aranda MR, Fournel P, Lemieux C: Renal enzymes during experimental diabetes mellitus in the rat: Role of insulin, carbohydrate metabolism, and ketoacidosis. Can J Physiol Pharmacol 62:70-75, 1984
    • (1984) Can J Physiol Pharmacol , vol.62 , pp. 70-75
    • Lemieux, G.1    Aranda, M.R.2    Fournel, P.3    Lemieux, C.4
  • 197
    • 0017370499 scopus 로고
    • The effects of starvation and experimental diabetes on phosphoenolpyruvate carboxykinase in the guinea pig
    • Elliott K, Pogson C: The effects of starvation and experimental diabetes on phosphoenolpyruvate carboxykinase in the guinea pig. Biochem J 164:357-361, 1977
    • (1977) Biochem J , vol.164 , pp. 357-361
    • Elliott, K.1    Pogson, C.2
  • 198
    • 0020073990 scopus 로고
    • Changes in metabolism of rat kidney and liver caused by experimental diabetes and by dietary sucrose
    • Kang S, Fears R, Noirot S, Mbanga J, Yudkin J: Changes in metabolism of rat kidney and liver caused by experimental diabetes and by dietary sucrose. Diabetologia 22:285-288, 1982
    • (1982) Diabetologia , vol.22 , pp. 285-288
    • Kang, S.1    Fears, R.2    Noirot, S.3    Mbanga, J.4    Yudkin, J.5
  • 201
    • 0024360863 scopus 로고
    • Amino acid metabolism in muscle and in whole body of man before and after ingestion of a single mixed meal
    • Elia M, Folmer P, Schlatman A, Goren A, Austin S: Amino acid metabolism in muscle and in whole body of man before and after ingestion of a single mixed meal. Am J Clin Nutr 49:1203-1210, 1989
    • (1989) Am J Clin Nutr , vol.49 , pp. 1203-1210
    • Elia, M.1    Folmer, P.2    Schlatman, A.3    Goren, A.4    Austin, S.5
  • 202
    • 0021885703 scopus 로고
    • Alanine and glutamine release from the human forearm: Effects of glucose administration
    • Elia M, Neale G, Livesey G: Alanine and glutamine release from the human forearm: Effects of glucose administration. Clin Sci 69:123-133, 1985
    • (1985) Clin Sci , vol.69 , pp. 123-133
    • Elia, M.1    Neale, G.2    Livesey, G.3
  • 203
    • 0020678748 scopus 로고
    • Effects of ingested steak and infused leucine on forearm metabolism in man and the fate of the carbon skeletons and amino groups of branched-chain amino acids
    • Elia M, Livesey G: Effects of ingested steak and infused leucine on forearm metabolism in man and the fate of the carbon skeletons and amino groups of branched-chain amino acids. Clin Sci 64:517-526, 1983
    • (1983) Clin Sci , vol.64 , pp. 517-526
    • Elia, M.1    Livesey, G.2
  • 205
    • 0020037515 scopus 로고
    • The effect of leucine infusion on substrate flux across the human forearm
    • Abumrad N, Robinson R, Gooch B, Lacy W: The effect of leucine infusion on substrate flux across the human forearm. J Surg Res 32:453-463, 1982
    • (1982) J Surg Res , vol.32 , pp. 453-463
    • Abumrad, N.1    Robinson, R.2    Gooch, B.3    Lacy, W.4
  • 208
    • 0019787843 scopus 로고
    • Leucine meal increases glutamine and total nitrogen release from forearm muscle
    • Aoki TT, Brennan MF, Fitzpatrick GF, Knight DC: Leucine meal increases glutamine and total nitrogen release from forearm muscle. J Clin Invest 68:1522-1528, 1981
    • (1981) J Clin Invest , vol.68 , pp. 1522-1528
    • Aoki, T.T.1    Brennan, M.F.2    Fitzpatrick, G.F.3    Knight, D.C.4
  • 209
    • 0025035561 scopus 로고
    • Splanchnic, renal and muscle clearance of alanylglutamine in man and organ fluxes of alaninc and glutamine when infused in free dual peptide forms
    • Lochs H, Roth E, Gasic S, Hubl W, Morse EL, Adibi SA: Splanchnic, renal and muscle clearance of alanylglutamine in man and organ fluxes of alaninc and glutamine when infused in free dual peptide forms. Metabolism 39:833-836, 1990
    • (1990) Metabolism , vol.39 , pp. 833-836
    • Lochs, H.1    Roth, E.2    Gasic, S.3    Hubl, W.4    Morse, E.L.5    Adibi, S.A.6
  • 210
    • 0019197010 scopus 로고
    • Influence of leucine on arterial concentrations and regional exchange of amino acids in healthy subjects
    • Hagenfeldt L, Eriksson S, Wahren J: Influence of leucine on arterial concentrations and regional exchange of amino acids in healthy subjects. Clin Sci 59:173-181, 1980
    • (1980) Clin Sci , vol.59 , pp. 173-181
    • Hagenfeldt, L.1    Eriksson, S.2    Wahren, J.3
  • 212
    • 0013597788 scopus 로고
    • The amino acid-induced secretion of glucagon
    • edited by Lefebvre P, New York, Springer-Verlag
    • Assan R, Marre M, Gormley M: The amino acid-induced secretion of glucagon, in Glucagon II, edited by Lefebvre P, New York, Springer-Verlag, 1983, p 19
    • (1983) Glucagon II , vol.2 , pp. 19
    • Assan, R.1    Marre, M.2    Gormley, M.3
  • 213
    • 0026349503 scopus 로고
    • Effect of stress hormones on transplanchic balance of exogenous amino acids in healthy man
    • Ratheiser K, Komjati M, Gasic S, Bratusch-Marrain P, Walhouse W: Effect of stress hormones on transplanchic balance of exogenous amino acids in healthy man. Metabolism 40:1298-1304. 1991
    • (1991) Metabolism , vol.40 , pp. 1298-1304
    • Ratheiser, K.1    Komjati, M.2    Gasic, S.3    Bratusch-Marrain, P.4    Walhouse, W.5
  • 214
    • 0018094811 scopus 로고
    • Effects of chronic renal insufficiency and metabolic acidosis on glutamine metabolism in man
    • Tizianello A, Deferrari G, Garibotto G, Gurreiri G: Effects of chronic renal insufficiency and metabolic acidosis on glutamine metabolism in man. Clin Sci Mol Med 55:391-397, 1978
    • (1978) Clin Sci Mol Med , vol.55 , pp. 391-397
    • Tizianello, A.1    Deferrari, G.2    Garibotto, G.3    Gurreiri, G.4
  • 216
    • 0000808509 scopus 로고
    • Amino acid extraction and ammonia metabolism by the human kidney during the prolonged administration of ammonium chloride
    • Owen OE, Robinson RR: Amino acid extraction and ammonia metabolism by the human kidney during the prolonged administration of ammonium chloride. J Clin Invest 42:263-276, 1963
    • (1963) J Clin Invest , vol.42 , pp. 263-276
    • Owen, O.E.1    Robinson, R.R.2
  • 218
    • 0025877124 scopus 로고
    • Amino acid metabolism in human subcutaneous tissue in vivo
    • Frayn KN, Khan K, Coppack SW, Elia M: Amino acid metabolism in human subcutaneous tissue in vivo. Clin Sci 80:471-474, 1990
    • (1990) Clin Sci , vol.80 , pp. 471-474
    • Frayn, K.N.1    Khan, K.2    Coppack, S.W.3    Elia, M.4


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