Dopamine D2 receptor occupancy in vivo by the novel atypical antipsychotic olanzapine - A 123I IBZM single photon emission tomography (SPET) study

Psychopharmacology

Volumn 124, Issue 1-2, 1996, Pages 148-153

  Pilowsky, L S ^a,b   Busatto, G F ^a   Taylor, M ^a   Costa, D C ^b   Sharma, T ^a   Sigmundsson, T ^a   Ell, P J ^b   Nohria, V ^c   Kerwin, R W ^d  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b MIDDLESEX HOSPITAL   (United Kingdom)

^c ELI LILLY AND COMPANY   (United States)

^d NONE

Author keywords

Atypical antipsychotic drugs; Clozapine; Dopamine D2 receptors; Olanzapine; Single photon emission tomography

Indexed keywords

2 IODOBENZAMIDE I 123; CLOZAPINE; DOPAMINE 2 RECEPTOR; HALOPERIDOL; IODINE 123; NEUROLEPTIC AGENT; OLANZAPINE; RISPERIDONE; UNCLASSIFIED DRUG; 3 IODO 2 HYDROXY 6 METHOXY N ((1 ETHYL 2 PYRROLIDINYL)METHYL)BENZAMIDE; 3-IODO-2-HYDROXY-6-METHOXY-N-((1-ETHYL-2-PYRROLIDINYL)METHYL)BENZAMIDE; BENZAMIDE DERIVATIVE; BENZODIAZEPINE DERIVATIVE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; PIRENZEPINE; PYRROLIDINE DERIVATIVE;

ADULT; AKATHISIA; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORPUS STRIATUM; DOUBLE BLIND PROCEDURE; EXTRAPYRAMIDAL SYMPTOM; HUMAN; IMAGE ANALYSIS; PARKINSONISM; PRIORITY JOURNAL; PSYCHIATRY; RATING SCALE; RECEPTOR OCCUPANCY; SCHIZOPHRENIA; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; COMPARATIVE STUDY; METABOLISM; MIDDLE AGED; SCINTISCANNING;

ADULT; ANTIPSYCHOTIC AGENTS; BENZAMIDES; BENZODIAZEPINES; CORPUS STRIATUM; HALOPERIDOL; HUMANS; MIDDLE AGED; PIRENZEPINE; PYRROLIDINES; RECEPTORS, DOPAMINE D2; SCHIZOPHRENIA; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0029658332     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02245615     Document Type: Article

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