Serum eosinophil cationic protein as a marker of eosinophilic inflammation in asthma

Clinical and Experimental Allergy

Volumn 28, Issue 2, 1998, Pages 233-240

  Niimi, A ^a   Amitani, R ^a   Suzuki, K ^a   Tanaka, E ^a   Murayama, T ^a   Kuze, F ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Asthma; Bronchial biopsy; Bronchoalveolar lavage; Disease activity; Eosinophil cationic protein; Eosinophils

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CELL MARKER; EOSINOPHIL CATIONIC PROTEIN; IMMUNOGLOBULIN E; METHACHOLINE;

ARTICLE; ASTHMA; BRONCHUS BIOPSY; CELL COUNT; CLINICAL ARTICLE; DISEASE ACTIVITY; DISEASE SEVERITY; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; LUNG LAVAGE; LUNG PARENCHYMA; PRIORITY JOURNAL;

ADULT; ASTHMA; BLOOD PROTEINS; BRONCHI; BRONCHIAL PROVOCATION TESTS; BRONCHITIS; BRONCHOALVEOLAR LAVAGE FLUID; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILIA; EOSINOPHILS; FEMALE; FORCED EXPIRATORY FLOW RATES; FORCED EXPIRATORY VOLUME; HUMANS; INFLAMMATION MEDIATORS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; RIBONUCLEASES;

EID: 0031950797     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.1998.00217.x     Document Type: Article

References (29)

1. Bousquet J, Chanez P, Lacoste JY et al. Eosinophilic inflammation in asthma. N Engl J Med 1990; 323:1033-9.
2. Bjornsdottir US, Quan SF, Busse WW. Eosinophils and asthma. In: Busse WW, Holgate ST, ed. Asthma and rhinitis. Boston: Blackwell Scientific Publications, 1995; 328-46.
3. Venge P. Serum measurements of eosinophil cationic protein (ECP) in bronchial asthma. Clin Exp Allergy 1993; 23 (Suppl 2):3-7.
4. Zimmerman B, Lanner A, Enander I et al. Total blood eosinophils, serum eosinophil cationic protein and eosinophil protein X in childhood asthma: relation to disease status and therapy. Clin Exp Allergy 1993; 23:564-70.
5. Koller DY, Herouy Y, Götz M, Hagel E, Urbanek R, Eichler I. Clinical value of monitoring eosinophil activity in asthma. Arch Dis Child 1995; 73:413-7.
6. Rao R, Frederick JM, Enander I, Gregson RK, Warner JA, Warner JO. Airway function correlates with circulating eosinophil, but not mast cell, markers of inflammation in childhood asthma. Clin Exp Allergy 1996; 26:789-93.
7. Ädelroth E, Rosenhall L, Johansson S-A, Linden M, Venge P. Inflammatory cells and eosinophilic activity in asthmatics investigated by bronchoalveolar lavage. The effects of antiasthmatic treatment with budesonide or terbutaline. Am Rev Respir Dis 1990; 142:91-9.
8. Claman DM, Boushey HA, Liu J, Wong H, Fahy JV. Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects. J Allergy Clin Immunol 1994; 94:861-9.
9. Virchow J-C, Jr., Hölscher U, Virchow C, Sr. Sputum ECP levels correlate with parameters of airflow obstruction. Am Rev Respir Dis 1992; 146:604-6.
10. National Heart Lung and Blood Institute, National Institute of Health, U.S.A. International consensus report on diagnosis and treatment of asthma. Clin Exp Allergy 1992; 22(Suppl.):1-72.
11. Workshop Summary and Guidelines. Investigative use of bronchoscopy, lavage, and bronchial biopsies in asthma and other airway diseases. J Allergy Clin Immunol 1991; 88:808-14.
12. Takishima T, Hida W, Sasaki H, Suzuki S, Sasaki T. Direct-writing recorder of the dose-response curves of the airway to methacholine. Chest 1981; 80:600-6.
13. Mochizuki H, Shigeta M, Kato M, Maeda S, Shimizu T, Morikawa A. Age-related changes in bronchial hyperreactivity to methacholine in asthmatic children. Am J Respir Crit Care Med 1995; 152:906-10.
14. Okayama M, Yafuso N, Nogami H, et al. A new method of inhalation challenge with propranolol; comparison with methacholine-induced bronchoconstriction and a role of vagal nerve activity. J Allergy Clin Immunol 1987; 80:291-9.
15. Amishima M, Munakata M, Ohtsuka Y, et al. Dairy farmers have increased methacholine bronchial responsiveness independent of sensitization to mold antigens. Am J Respir Crit Care Med 1995; 151:1794-8.
16. Ishii M, Hida W, Suzuki S, Ichinose M, Sasaki H, Takishima T. Comparison of intermittent and continuous inhalation provocation tests. Ann Allergy 1989; 62:223-8.
17. Cockcrott DW, Killian DN, Mellon JJA, Hargreave FE. Bronchial reactivity to inhaled histamine: a method and clinical survey. Clin Allergy 1977; 7:235-43.
18. American Thoracic Society. Standardization of spirometry. Am J Respir Crit Care Med 1995; 152:1107-36.
19. Ohashi Y, Motojima S, Fukuda T, Makino S. Airway hyperresponsiveness, increased intracellular spaces of bronchial epithelium, and increased infiltration of eosinophils and lymphocytes in bronchial mucosa in asthma. Am Rev Respir Dis 1992; 145:1469-76.
20. Sears MR. Editorial. Increasing asthma mortality - Fact or artifact? J Allergy Clin Immunol 1988; 82:957-60.
21. Grigg J, Venge P. Inflammatory markers of outcome. Eur Respir J 1996; 9 (Suppl. 21): 16s-21s.
22. Twentyman OP, Sams VR, Holgate ST. Albuterol and nedocromil sodium affect airway and leukocyte responses to allergen. Am Rev Respir Dis 1993; 147:1425-30.
23. Koshino T, Morita Y, Ito K, Teshima S, Sano Y. Activation of bone marrow eosinophils in asthma. Chest 1993; 103:1931-2.
24. Ahlstedt S. Clinical application of eosinophil cationic protein in asthma. Allergy Proc 1995; 16:59-62.
25. Lacoste J-Y, Bousquet J, Chanez P, et al. Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease. J Allergy Clin Immunol 1993; 92:537-48.
26. Robinson DS, Assoufi B, Durham SR, Kay AB. Eosinophil cationic protein (ECP) and eosinophil protein X (EPX) concentrations in serum and bronchial lavage fluid in asthma. Effect of prednisolone treatment. Clin Exp Allergy 1995; 25: 1118-27.
27. Venge P. Editorial. Monitoring of asthma inflammation by serum measurements of eosinophil cationic protein (ECP). A new clinical approach to asthma management. Respir Med 1995; 89:1-2.
28. Robinson DS. Editorial. Eosinophils and asthma. What do measurements tell us? Clin Exp Allergy 1995; 25:795-8.
29. Ulrik CS. Peripheral eosinophil counts as a marker of disease activity in intrinsic and extrinsic asthma. Clin Exp Allergy 1995; 25:820-7.