Comparative nephritogenicity of two monoclonal antibodies that recognize different epitopes of rat Thy-1.1 molecule

Nephron

Volumn 78, Issue 4, 1998, Pages 453-463

  Nakayama, H ^a   Oite, T ^a   Kawachi, H ^a   Morioka, T ^a   Kobayashi, H ^a   Orikasa, M ^a   Arakawa, M ^a   Shimizu, F ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

Anti Thy 1 monoclonal antibody; Anti Thy 1 nephritis; Comparative nephritogenicity, monoclonal antibodies

Indexed keywords

ALPHA ACTIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C9; EPITOPE; KIDNEY ANTIGEN; MESSENGER RNA; MONOCLONAL ANTIBODY; THY 1 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; FEMALE; IMMUNE COMPLEX NEPHRITIS; IMMUNOHISTOCHEMISTRY; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT; SMOOTH MUSCLE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGENS, THY-1; BLOTTING, NORTHERN; DISEASE MODELS, ANIMAL; EPITOPES; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLOMERULAR MESANGIUM; GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE; PROTEINURIA; RATS; RATS, WISTAR;

EID: 0031957261     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000044975     Document Type: Article

References (6)

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3. Border WA, Okuda S, Languino LR, Sporn MB, Ruoslahti E: Suppression of experimental glomerulonephritis by antiserum against transforming growth factor beta 1. Nature 1990;346:371-374.
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5. Okuda S, Languino LR, Ruoslahti E, Border WA: Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. J Clin Invest 1990;86:453-462.
6. Yamamoto T, Wilson CB: Quantitative and qualitative studies of antibody-induced mesangial cell damage in the rat. Kidney Int 1987;32:514-525.