Blocking angiotensin II ameliorates proteinuria and glomerular lesions in progressive mesangioproliferative glomerulonephritis

Kidney International

Volumn 55, Issue 3, 1999, Pages 877-889

  Nakamura, Takamichi ^a   Obata, Jun Ei ^b   Kimura, Hideaki ^b   Ohno, Shinichi ^b   Yoshida, Yoji ^b   Kawachi, Hiroshi ^b   Shimizu, Fujio ^b  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b NONE

Author keywords

ACE inhibitors; Bradykinin; Progressive renal disease; Renin angiotensin system; TGF

Indexed keywords

ANGIOTENSIN; BRADYKININ; CANDESARTAN; CILAZAPRIL; COLLAGEN TYPE 1; COLLAGEN TYPE 3; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDRALAZINE; ICATIBANT; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE CLEARANCE; EXTRACELLULAR MATRIX; IMMUNOHISTOCHEMISTRY; KIDNEY FAILURE; MALE; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROLIFERATIVE GLOMERULONEPHRITIS; PROTEINURIA; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SYSTOLIC BLOOD PRESSURE;

EID: 0032988331     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1999.055003877.x     Document Type: Article

References (62)

1. Anderson S, Rennke HG, Brenner BM: Therapeutic advantages of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat. J Clin Invest 77:1993-2000, 1986
2. Diamond JR, Anderson S: Irreversible tubulointerstitial damage associated with chronic aminonucleoside nephrosis: Amelioration of angiotensin converting enzyme inhibition. Am J Pathol 137:1323-1332, 1990
3. Komatsu K, Frohlich ED, Ono H, Ono Y, Numabe A, Willis GW: Glomerular dynamics and morphology of aged spontaneously hypertensive rats: Effects of angiotensin-converting enzyme inhibition. Hypertension 25:207-213, 1995
4. Remuzzi A, Puntorieri S, Battaglia C, Bertani T, Remuzzi G: Angiotensin converting enzyme inhibition ameliorates glomerular filtration of macromolecules and water and lessens glomerular injury in the rats. J Clin Invest 85:541-549, 1990
5. Erdos EG: Angiotensin I converting enzyme. Circ Res 36:247-255, 1975
6. Verma PS, Gagnon JA, Miller RL: Intrarenal kallikrein-kinin activity in acute renovascular hypertension. Renal Physiol 10:311-317, 1987
7. Campbell DJ, Kladis A, Duncan A-M: Effects of converting enzyme inhibitors on angiotensin and bradykinin peptides. Hypertension 23:439-449, 1994
8. Johnston CI, Clappison BH, Anderson WP, Yasujima M: Effect of angiotensin-converting enzyme inhibition on circulating and local kinin levels. Am J Cardiol 49:1401-1404, 1982
9. Edwards RM: Response of isolated renal arterioles to acetylcholine, dopamine, and bradykinin. Am J Physiol 248:F183-F189, 1985
10. Linz W, Wiemer G, Gohlke P, Unger T, Scholkens BA: Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors. Lab Invest 47:25-48, 1995
11. Hutchison FN, Schambelan M, Kaysen GA: Modulation of albuminuria by dietary protein and converting enzyme inhibition. Am J Physiol 253(Renal Fluid Electrolyte Physiol 22):F719-F725, 1987
12. Hutchison FN, Martin VI: Effects of modulation of renal kallikrein-kinin system in nephrotic syndrome. Am J Physiol 258(Renal Fluid Electrolyte Physiol 27):F1237-F1244, 1990
13. Hutchison FN, Webster SK: Effect of ANG II receptor antagonist on albuminuria and renal function in passive Heymann nephritis. Am J Physiol 263(Renal Fluid Electrolyte Physiol 32):F311-F318, 1992
14. Lafayette RA, Mayer G, Park SK, Meyer TW: Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass. J Clin Invest 90:766-771, 1992
15. Kon R, Sugihara K, Tatematsu A, Fogo A: Internephron heterogeneity of growth factors and sclerosis: Modulation of platelet-derived growth factor by angiotensin II. Kidney Int 47:131-139, 1995
16. Kim S, Ohta K, Hamaguchi A, Omura T, Yukimura T, Miura K, Inada Y, Wada T, Ishimura Y, Chatani F, Iwao H: Contribution of renal angiotensin II type 1 receptor to gene expressions in hypertension-induced renal injury. Kidney Int 46: 1346-1358, 1994
17. Whitebread S, Mele M, Kamber B, De Gasparo M: Preliminary biochemical characterization of two angiotensin II receptor subtypes. Biochem Biophys Res Commun 163:284-291, 1989
18. Nakajima M, Hutchinson HG, Fujinaga M, Hayashida W, Morishita R, Zhang L, Horiuchi M, Pratt RE, Dzau VJ: The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: Gain-of-function study using gene transfer. Proc Natl Acad Sci USA 92:10663-10667, 1995
19. Klahr S, Schreiner G, Ichikawa I: The progression of renal disease. N Engl J Med 318:1657-1666, 1988
20. Border WA, Ruoslahti E: Transforming growth factor-β in disease: The dark side of tissue repair. J Clin Invest 90:1-7, 1992
21. Border WA, Noble NA: Transforming growth factor β in tissue fibrosis. N Engl J Med 331:1286-1292, 1994
22. Yamamoto T, Noble NA, Miller DE, Border WA: Sustained expression of TGF-β underlies development of progressive kidney fibrosis. Kidney Int 45:916-927, 1994
23. Obberghen-Schilling EV, Roche NS, Flanders KC, Sporn MB, Roberts AB: Transforming growth factor β1 positively regulates its own expression in normal and transforming cells. J Biol Chem 263:7741-7746, 1988
24. Kagami S, Border WA, Miller DE, Noble NA: Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-β expression in rat mesangial cells. J Clin Invest 92:2431-2437, 1994
25. Shankland SJ, Ly H, Thai K, Scholey JW: Increased glomerular capillary pressure alters glomerular cytokine expression. Circ Res 75:844-853, 1994
26. Studer RK, Cerucertis FR, Craven PA: Nitric oxide suppresses increases in mesangial cell protein kinase C, transforming growth factor β, and fibronectin synthesis induced by thromboxane. J Am Soc Nephrol 7:999-1005, 1996
27. Ruiz-Ortega M, Gonzales S, Seron D, Condon E, Bustos C. Largo R, Gonzales E, Ortez A, Edigo J: ACE inhibition reduces proteinuria, glomerular lesions and extracellular matrix production in a normotensive rat model of immune complex nephritis. Kidney Int 48:1778-1791, 1995
28. Cheng QL, Orikasa M, Morioka T, Kawachi H, Chen XM, Oite T, Shimizu F: Progressive renal lesions induced by administration of monoclonal antibody 1 -22-3 to unilaterally nephrectomized rats. Clin Exp Immunol 102:181-185, 1995
29. Shimizu F, Fukagawa M, Yamauchi S, Taniyama M, Komemushi S, Margolin S, Kurokawa K: Pirfenidone prevents the progression of irreversible glomerular sclerotic lesions in rats. Nephrology 3:315-322, 1997
30. Gohlke P, Linz W, Scholkens BA, Kuwer I, Bartebbach S, Schnell A, Unger T: Angiotensin-converting enzyme inhibition improves cardiac function: Role of bradykinin. Hypertension 23:411-418, 1994
31. Nakamura T, Obata J, Kuroyanagi R, Kimura H, Ikeda Y, Takano H, Naito A, Yoshida Y: Involvement of angiotensin II in glomerulosclerosis of stroke-prone spontaneously hypertensive rats. Kidney Int 49:(Suppl 55):S109-S112, 1996
32. Kawachi H, Matsui K, Orikasa M, Morioka T, Oite T, Shimizu F: Quantitative studies of monoclonal antibody 5-1-6-induced proteinuric state in rats. Clin Exp Immunol 87:215-219, 1992
33. Kawachi H, Orikasa M, Matsui K, Iwanaga T, Toyobe S, Oite T, Shimizu F: Epitope-specific induction of mesangial lesions with proteinuria by a MoAb against mesangial cell surface antigen. Clin Exp Immunol 88:399-404, 1992
34. McConahey PJ, Dixon FJ: A method of trace iodination of protein for immunologic studies. Int Arch Allergy 29:185-189, 1986
35. Raij L, Azar S, Keane W: Mesangial injury, hypertension, and progressive glomerular damage in Dahl rats. Kidney Int 26:137-143, 1984
36. Yoshioka K, Takemura T, Murakami K: Transforming growth factor-β protein and mRNA in glomeruli in normal and diseased human kidneys. Lab Invest 68:154-163, 1993
37. Flanders KC, Roberts AB, Ling N, Fleurdleye BE, Sporn MB: Antibodies to peptide determinants in transforming growth factor-β and their applications. Biochem 27:739-746, 1988
38. Nakamura T: Monclonal antibodies to human glomerular antigens. II. Using human adult kidney components as antigens. Clin Immunol Immunopathol 41:399-408, 1986
39. Kimura K, Tojo A, Matsuoka H, Sugimoto T: Renal arteriolar diameters in spontaneously hypertensive rats. Hypertension 18:101-110, 1991
40. Chomczynski P, Sacchi N: Single step method of RNA isolation. Anal Biochem 162:156-159, 1987
41. Tsuji T, Okada F, Yamaguchi K, Nakamura T: Molecular cloning of the large subunit of TGF-β masking protein and expression of the mRNA in various rat tissues. Proc Natl Acad Sci USA 87:8835-8839, 1990
42. Genovese C, Rowe D, Kream B: Construction of DNA sequences complementary to rat alpha 1 and alpha 2 collagen mRNA and their use in studying the regulation of type 1 collagen synthesis by 1,25-dihydroxyvitamin D. Biochem 23:6210-6216, 1984
43. Matsuki Y, Nakashima M, Amizuka N, Warshawsky H, Goltzman D, Yamada KM, Yamada Y: A compilation of partial sequences of randomly selected cDNA clones from the rat incisor. J Dental Res 74:307-312, 1995
44. Fort P, Marry L, Piechaczyk M, Sabrouty SE, Dani C, Jeanteur P, Blanchard JM: Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenese multigene family. Nucleic Acid Res 13:1431-1442, 1985
45. Ziai F, Ots M, Provoost AP, Troy JL, Rennke HG, Brenner BM, Mackenzie HS: The angiotensin receptor antagonist, irbesartan, reduces renal injury in experimental chronic renal failure. Kidney Int 50(Suppl 57):S132-S136, 1996
46. Kohara K, Mikami H, Okuda N, Higaki J, Ogihara T: Angiotensin blockade and the progression of renal damage in the spontaneously hypertensive rat. Hypertension 21:975-979, 1993
47. Tanaka R, Kon V, Yoshioka T, Ichikawa I, Fogo A: Angiotensin converting enzyme inhibitor modulates glomerular function and structure by distinct mechanisms. Kidney Int 45:537-543, 1994
48. Anderson A, Tolbert E, Esparza A, Dworkin L: Effects of an ACE inhibitor vs. an AII antagonist on hemodynamics, growth, and injury in spontaneously hypertensive rats. (abstract) J Am Soc Nephrol 7:1849, 1996
49. Noda M, Fukuda R, Matsuo T, Ohta M, Nagano H, Imura Y, Nishikawa K, Shibouta Y: Effects of candesartan cilexetile (TCV-116) and enalapril in 5/6 nephrectomized rats. Kidney Int 52(Suppl 63):S136-S139, 1997
50. Bascands JL, Pecher C, Cabos G, Girolami JP: B2-kinin receptor like binding in rat glomerular membranes. Biochem Biophys Res Commun 158:99-104, 1989
51. Bascand JL, Pecher C, Rouaud S, Emond C, Tack JL, Bastie MJ, Burch R, Regoli D, Girolami JP: Evidence for existence of two distinct bradykinin receptors on rat mesangial cells. Am J Physiol 264:F548-F556, 1993
52. Regoli D, Barabe J: Pharmacology of bradykinin and related kinins. Pharmacol Rev 32:1-46, 1980
53. Giorolami JP, Ouardani M, Bascands JL, Pecher C, Bompart G, Leung-Tack J: Comparison of B1 and B2 receptor activation on intracellular calcium, cell proliferation, and extracellular collagen secretion in mesangial cells from normal and diabetic rats. Can J Physiol Pharmacol 73:848-853, 1995
54. Guimaraes JA, Viera MAR, Cramargo MJF, Maack T: Renal vasoconstrictive effect of kinins mediated by B1-kinin receptors. Eur J Pharmacol 130:177-185, 1986
55. Bao G, Qadri F, Stauss B, Stauss H, Gohlke P, Unger T: HOE-140, a new highly potent and long-acting bradykinin antagonist in conscious rats. Eur J Pharmacol 200:179-182, 1991
56. Hock FG, Wirth K, Albus U, Linz W, Gerhards HJ, Weimer G, Henke S, Breipohl G, Konig W, Knolle J, Scholkens BA: Hoe 140 a new potent and long acting bradykinin-antagonist: In vitro studies. Br J Pharmacol 102:769-773, 1991
57. Wirth K, Hock FG, Albus U, Linz W, Alpermann HG, Anagnostopoulos H, Henke S, Breipohl G, Konig W, Knolle J, Scholkens BA: Hoe 140 a new potent and long acting bradykinin-antagonist: In vivo studies. Br J Pharmacol 102:774-777, 1991
58. Nakamura T, Miller D, Ruoslahti E, Border WA: Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-β1. Kidney Int 41:1213-1221, 1992
59. Shimizu T, Fukagawa M, Kuroda T, Hata S, Iwasaki Y, Nemoto M, Shirai K, Yamauchi S, Margolin SB, Shimizu F, Kurokawa K: Pirfenidone prevents collagen accumulation in the remnant kidney in rats with partial nephrectomy. Kidney Int 52(Suppl 63):S239-S243, 1997
60. Ichikawa I, Miele JF, Brenner BM: Reversal of renal cortical actions of angiotensin II by verapamil and manganese. Kidney Int 16:137-147, 1979
61. Riser BL, Cortes P, Zhao X, Bernstein J, Dumler F, Narins RG: Intraglomerular pressure and mesangial stretching stimulate extracellular matrix formation in the rat. J Clin Invest 90:1932-1943, 1992
62. Riser BL, Cortes P, Heilig C, Grondin JM, Ladson-Wofford S, Patterson D, Narins RG: Cyclic stretching selectively up-regulates transforming growth factor-β isoforms in cultured mesangial cells. Am J Pathol 148:1915-1923, 1996