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Volumn 50, Issue 5, 1996, Pages 1167-1177

Three new toxins from the scorpion Pandinus imperator selectively block certain voltage-gated K+ channels

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL; SCORPION VENOM;

EID: 0029807962     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (39)

References (40)
  • 1
    • 0028983387 scopus 로고
    • + channel-blocking peptides
    • + channel-blocking peptides. Neuron 15:5-10 (1995).
    • (1995) Neuron , vol.15 , pp. 5-10
    • Miller, C.1
  • 2
    • 0028276482 scopus 로고
    • + channel: Peptide and channel residues mediating molecular recognition
    • + channel: peptide and channel residues mediating molecular recognition. Neuron 12:1377-1388 (1994).
    • (1994) Neuron , vol.12 , pp. 1377-1388
    • Goldstein, S.A.N.1    Pheasant, D.J.2    Miller, C.3
  • 3
    • 0028987938 scopus 로고
    • + channel pore through mutant cycles with a peptide inhibitor
    • + channel pore through mutant cycles with a peptide inhibitor. Science (Washington D. C.) 268:307-310 (1995).
    • (1995) Science (Washington D. C.) , vol.268 , pp. 307-310
    • Hidalgo, P.1    MacKinnon, R.2
  • 4
    • 0028117321 scopus 로고
    • + channel structure from a complete functional map of the molecular surface of charybdotoxin
    • + channel structure from a complete functional map of the molecular surface of charybdotoxin. Biochemistry 33:443-450 (1994).
    • (1994) Biochemistry , vol.33 , pp. 443-450
    • Stampe, P.1    Kolmakova-Partensky, L.2    Miller, C.3
  • 8
    • 0027320629 scopus 로고
    • Purification, characterization, and biosynthesis of Centruroides magaritatus venom that selectively inhibits voltage-dependent potassium channels
    • Garcia-Calvo, M., R. J. Leonard, J. Novick, S. P. Stevens, W. Schmalhofer, G. J. Kaczorowski, and M. L. Garcia. Purification, characterization, and biosynthesis of Centruroides magaritatus venom that selectively inhibits voltage-dependent potassium channels. J. Biol. Chem. 268:18866-18874 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 18866-18874
    • Garcia-Calvo, M.1    Leonard, R.J.2    Novick, J.3    Stevens, S.P.4    Schmalhofer, W.5    Kaczorowski, G.J.6    Garcia, M.L.7
  • 9
    • 0025299296 scopus 로고
    • + channel receptor
    • + channel receptor. Biochemistry 29:5320-5325 (1990).
    • (1990) Biochemistry , vol.29 , pp. 5320-5325
    • Miller, C.1
  • 10
    • 0023431924 scopus 로고
    • Pandinus Imperator scorpion venom blocks voltage-gated potassium channels in nerve fibers
    • Pappone, P. A., and M. D. Cahalan. Pandinus Imperator scorpion venom blocks voltage-gated potassium channels in nerve fibers. J. Neurosci. 7:3300-3305 (1987).
    • (1987) J. Neurosci. , vol.7 , pp. 3300-3305
    • Pappone, P.A.1    Cahalan, M.D.2
  • 12
    • 0026342510 scopus 로고
    • Polypeptide toxins from the venoms of old world and new world scorpions preferentially block different potassium channels
    • Blaustein, M. P., R. S. Rogowski, M. J. Schneider, and B. K. Krueger. Polypeptide toxins from the venoms of old world and new world scorpions preferentially block different potassium channels. Mol. Pharmacol. 40: 932-942 (1991).
    • (1991) Mol. Pharmacol. , vol.40 , pp. 932-942
    • Blaustein, M.P.1    Rogowski, R.S.2    Schneider, M.J.3    Krueger, B.K.4
  • 13
    • 0023472472 scopus 로고
    • Tricine-sodium dodecyl sulfatepolyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
    • Schägger, H., and G. von Jagow. Tricine-sodium dodecyl sulfatepolyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166:368-379 (1987).
    • (1987) Anal. Biochem. , vol.166 , pp. 368-379
    • Schägger, H.1    Von Jagow, G.2
  • 16
    • 0024444889 scopus 로고
    • Cloning and expression of a synthetic gene for Cerebratulus lacteus neurotoxin B-IV
    • Howell, M. L., and K. M. Blumenthal. Cloning and expression of a synthetic gene for Cerebratulus lacteus neurotoxin B-IV. J. Biol. Chem. 264: 15268-15273 (1989).
    • (1989) J. Biol. Chem. , vol.264 , pp. 15268-15273
    • Howell, M.L.1    Blumenthal, K.M.2
  • 18
    • 0026418431 scopus 로고
    • Refined structure of charybdotoxin: Common motifs in scorpion toxins and insect defensins
    • Bontems, F., C. Roumestand, B. Gilquin, A. Menez, and F. Toma. Refined structure of charybdotoxin: common motifs in scorpion toxins and insect defensins. Science (Washington D. C.) 254:1521-1523 (1991).
    • (1991) Science (Washington D. C.) , vol.254 , pp. 1521-1523
    • Bontems, F.1    Roumestand, C.2    Gilquin, B.3    Menez, A.4    Toma, F.5
  • 19
    • 0028245287 scopus 로고
    • Positively charged amino acid residues located similarly in sea anemone and scorpion toxins
    • Loret, E. P., R. M. del Valle, P. Mansuelle, F. Sampieri, and H. Rochat. Positively charged amino acid residues located similarly in sea anemone and scorpion toxins. J. Biol. Chem. 269:16785-16788 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 16785-16788
    • Loret, E.P.1    Del Valle, R.M.2    Mansuelle, P.3    Sampieri, F.4    Rochat, H.5
  • 20
    • 0026726528 scopus 로고
    • Analysis of side-chain organization on a refined model of charybdotoxin: Structural and functional implications
    • Bontems, F., B. Gilquin, C. Roumestand, A. Menez, and F. Toma. Analysis of side-chain organization on a refined model of charybdotoxin: structural and functional implications. Biochemistry 31:7756-7764 (1992).
    • (1992) Biochemistry , vol.31 , pp. 7756-7764
    • Bontems, F.1    Gilquin, B.2    Roumestand, C.3    Menez, A.4    Toma, F.5
  • 21
    • 0021895499 scopus 로고
    • Potassium channels in isolated presynaptic nerve terminals from rat brain
    • Bartschat, D. K., and M. P. Blaustein. Potassium channels in isolated presynaptic nerve terminals from rat brain. J. Physiol. 361:419-440 (1985).
    • (1985) J. Physiol. , vol.361 , pp. 419-440
    • Bartschat, D.K.1    Blaustein, M.P.2
  • 22
    • 0021895501 scopus 로고
    • Calcium-activated potassium channels in isolated presynaptic nerve terminals from rat brain
    • Bartschat, D. K., and M. P. Blaustein. Calcium-activated potassium channels in isolated presynaptic nerve terminals from rat brain. J. Physiol. 361:441-457 (1985).
    • (1985) J. Physiol. , vol.361 , pp. 441-457
    • Bartschat, D.K.1    Blaustein, M.P.2
  • 23
    • 0023747366 scopus 로고
    • Four polypeptide components of green mamba venom selectively block certain potassium channels in rat brain synaptosomes
    • Benishin, C. G., R. G. Sorensen, W. E. Brown, B. K. Krueger, and M. P. Blaustein. Four polypeptide components of green mamba venom selectively block certain potassium channels in rat brain synaptosomes. Mol. Pharmacol. 34:152-159 (1988).
    • (1988) Mol. Pharmacol. , vol.34 , pp. 152-159
    • Benishin, C.G.1    Sorensen, R.G.2    Brown, W.E.3    Krueger, B.K.4    Blaustein, M.P.5
  • 24
    • 0024413482 scopus 로고
    • Charybdotoxin blocks both Ca-activated K channels and Ca-independent voltage-gated K channels in rat brain synaptosomes
    • Schneider, M. J., R. S. Rogowski, B. K. Krueger, and M. P. Blaustein. Charybdotoxin blocks both Ca-activated K channels and Ca-independent voltage-gated K channels in rat brain synaptosomes. FEBS Lett. 250:433-436 (1989).
    • (1989) FEBS Lett. , vol.250 , pp. 433-436
    • Schneider, M.J.1    Rogowski, R.S.2    Krueger, B.K.3    Blaustein, M.P.4
  • 25
    • 0018677892 scopus 로고
    • The effects of some organic "calcium antagonists" on calcium influx in presynaptic nerve terminals
    • Nachshen, D. A., and M. P. Blaustein. The effects of some organic "calcium antagonists" on calcium influx in presynaptic nerve terminals. Mol. Pharmacol. 16:579-586 (1979).
    • (1979) Mol. Pharmacol. , vol.16 , pp. 579-586
    • Nachshen, D.A.1    Blaustein, M.P.2
  • 27
    • 0029572430 scopus 로고
    • Determination of the three-dimensional solution structure of noxiustoxin: Analysis of structural differences with related short-chain scorpion toxins
    • Dauplais, M., B. Gilquin, L. D. Possani, R. Gurrola-Briones, C. Roumestand, and A. Menez. Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins. Biochemistry 34:16563-16573 (1995).
    • (1995) Biochemistry , vol.34 , pp. 16563-16573
    • Dauplais, M.1    Gilquin, B.2    Possani, L.D.3    Gurrola-Briones, R.4    Roumestand, C.5    Menez, A.6
  • 29
    • 0028070528 scopus 로고
    • Primary and NMR three-dimensional structure determination of a novel crustacean toxin from the venom of the scorpion Centruroides limpidus limpidus Karsch
    • Lebreton, F., M. Delepierre, A. M. Ramírez, C. Balderas, and L. D. Possani. Primary and NMR three-dimensional structure determination of a novel crustacean toxin from the venom of the scorpion Centruroides limpidus limpidus Karsch. Biochemistry 33:11135-11149 (1994).
    • (1994) Biochemistry , vol.33 , pp. 11135-11149
    • Lebreton, F.1    Delepierre, M.2    Ramírez, A.M.3    Balderas, C.4    Possani, L.D.5
  • 30
    • 0028864511 scopus 로고
    • Combinatorial peptide libraries in drug design: Lessons from venomous cone snails
    • Olivera, B. M., D. R. Hillyard, M. Marsh, and D. Yoshikami. Combinatorial peptide libraries in drug design: lessons from venomous cone snails. Trends Biotech. 13:422-426 (1995).
    • (1995) Trends Biotech. , vol.13 , pp. 422-426
    • Olivera, B.M.1    Hillyard, D.R.2    Marsh, M.3    Yoshikami, D.4
  • 36
    • 0026781766 scopus 로고
    • 1H nuclear magnetic resonance spectroscopy
    • 1H nuclear magnetic resonance spectroscopy. Biochemistry 31:8151-8159 (1992).
    • (1992) Biochemistry , vol.31 , pp. 8151-8159
    • Johnson, B.A.1    Sugg, E.E.2
  • 38
    • 0029113242 scopus 로고
    • Solution structure of the potassium channel inhibitor agitoxin 2: Caliper for probing channel geometry
    • Krezel, A. M., C. Kasibhatla, P. Hidalgo, R. MacKinnon, and G. Wagner. Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry. Prot. Sci. 4:1478-1489 (1995).
    • (1995) Prot. Sci. , vol.4 , pp. 1478-1489
    • Krezel, A.M.1    Kasibhatla, C.2    Hidalgo, P.3    MacKinnon, R.4    Wagner, G.5
  • 39
    • 1842297763 scopus 로고    scopus 로고
    • Sequence-specific assignments and secondary structure determination of a toxin from Pandinus imperator (PiTX-Kα) using NMR spectroscopy
    • Tenenholz, T., R. S. Rogowski, J. C. Amburgey, J. C. Collins, T. A. Gustafson, M. P. Blaustein, and D. J. Weber. Sequence-specific assignments and secondary structure determination of a toxin from Pandinus imperator (PiTX-Kα) using NMR spectroscopy. Biophys. J. 70:A59 (1996).
    • (1996) Biophys. J. , vol.70
    • Tenenholz, T.1    Rogowski, R.S.2    Amburgey, J.C.3    Collins, J.C.4    Gustafson, T.A.5    Blaustein, M.P.6    Weber, D.J.7
  • 40
    • 0006117915 scopus 로고
    • Purification, sequence, and model structure of charybdotoxin, a potent selective inhibitor of calcium-activated potassium channels. Proc
    • Giminez-Gallego, G., M. A. Navia, J. P. Rubin, G. M. Katz, G. J. Kaczorowski, and M. L. Garcia. Purification, sequence, and model structure of charybdotoxin, a potent selective inhibitor of calcium-activated potassium channels. Proc. Natl. Acad. Sci. USA 85:3329-3333 (1988).
    • (1988) Natl. Acad. Sci. USA , vol.85 , pp. 3329-3333
    • Giminez-Gallego, G.1    Navia, M.A.2    Rubin, J.P.3    Katz, G.M.4    Kaczorowski, G.J.5    Garcia, M.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.