메뉴 건너뛰기




Volumn 52, Issue 5, 1999, Pages 480-484

UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. IV. Comparative studies of UK-2A with antimycin A3 on cytotoxic activity and reactive oxygen species generation in LLC-PK1 cells

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIFUNGAL AGENT; ANTIMYCIN A1; REACTIVE OXYGEN METABOLITE; UK 2A; UK 2B; UK 2C; UK 2D; UNCLASSIFIED DRUG;

EID: 0032971831     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.52.480     Document Type: Article
Times cited : (26)

References (23)
  • 1
    • 0029784909 scopus 로고    scopus 로고
    • UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. I. Fermentation, isolation and biological properties
    • UEKI, M.; KBE, M. HANAFI, K. SHIBATA, T. TANAKA & M. TANIGUCHI: UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. I. Fermentation, isolation and biological properties. J. Antibiotics 49: 639-643, 1996
    • (1996) J. Antibiotics , vol.49 , pp. 639-643
    • Ueki, M.1    Kbe, M.H.2    Shibata, K.3    Tanaka, T.4    Taniguchi, M.5
  • 2
    • 0030464228 scopus 로고    scopus 로고
    • UK-2A, B, C, and D, novel antifungal antibiotics from Streptomyces sp. 517-02. II. Structure elucidation
    • HANAFI, M.; K. SHIBATA, M. UEKI & M. TANIGUCHI: UK-2A, B, C, and D, novel antifungal antibiotics from Streptomyces sp. 517-02. II. Structure elucidation. J. Antibiotics 49: 1095-1100, 1996
    • (1996) J. Antibiotics , vol.49 , pp. 1095-1100
    • Hanafi, M.1    Shibata, K.2    Ueki, M.3    Taniguchi, M.4
  • 3
    • 0032442137 scopus 로고    scopus 로고
    • UK-2A, B, C, and D, novel antifungal antibiotics from Streptomyces sp. 517-02. III. Absolute configuration of an antifungal antibiotic, UK-2A, and consideration of its conformation
    • UEKI, M.; M. HANAFI, J. FUJII, O. SAKANAKA, K. IINUMA, M. UEKI & M. TANIGUCHI: UK-2A, B, C, and D, novel antifungal antibiotics from Streptomyces sp. 517-02. III. Absolute configuration of an antifungal antibiotic, UK-2A, and consideration of its conformation. J. Antibiotics 51: 1113-1116, 1998
    • (1998) J. Antibiotics , vol.51 , pp. 1113-1116
    • Ueki, M.1    Kbe2    Hanafi, M.3    Fujii, J.4    Sakanaka, O.5    Iinuma, K.6    Ueki, M.7    Taniguchi, M.8
  • 4
    • 0031441824 scopus 로고    scopus 로고
    • The mode of action of UK-2A and UK-3A, novel antifungal antibiotics from Streptomyces sp. 517-02
    • UEKI, M. & M. TANIGUCHI: The mode of action of UK-2A and UK-3A, novel antifungal antibiotics from Streptomyces sp. 517-02. J. Antibiotics 50: 1052-1057, 1997
    • (1997) J. Antibiotics , vol.50 , pp. 1052-1057
    • Ueki, M.1    Taniguchi, M.2
  • 5
    • 0020479807 scopus 로고
    • Import of proteins into mitochondria
    • DAUN, G.; P. C. BOHNI & G. SCHATZ: Import of proteins into mitochondria. J. Biol. Chem. 257: 13028-13033, 1982
    • (1982) J. Biol. Chem. , vol.257 , pp. 13028-13033
    • Daun, G.1    Bohni, P.C.2    Schatz, G.3
  • 7
    • 0029736434 scopus 로고    scopus 로고
    • Role of reaqctive oxygen metabolites in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells
    • HAGAR, H.; N. UEDA & S. V. SHAH: Role of reaqctive oxygen metabolites in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. Am. J. Physiol. 271: F209-F215, 1996
    • (1996) Am. J. Physiol. , vol.271
    • Hagar, H.1    Ueda, N.2    Shah, S.V.3
  • 8
    • 0030798072 scopus 로고    scopus 로고
    • Role of caspases (ICE/CED 3 proteases) in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A
    • KAUSHAL, G. P.; N. UEDA & S. V. SHAH: Role of caspases (ICE/CED 3 proteases) in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A. Kidney Int. 52: 438-445, 1997
    • (1997) Kidney Int. , vol.52 , pp. 438-445
    • Kaushal, G.P.1    Ueda, N.2    Shah, S.V.3
  • 10
    • 0031848460 scopus 로고    scopus 로고
    • Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells
    • UEDA, N.; G. P. KAUSHAL, X. HONG & S. V. SHAH: Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. Kidney Int. 54: 399-406, 1998
    • (1998) Kidney Int. , vol.54 , pp. 399-406
    • Ueda, N.1    Kaushal, G.P.2    Hong, X.3    Shah, S.V.4
  • 11
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • MOSMANN, T.: Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Method. 65: 55-63, 1983
    • (1983) J. Immunol. Method. , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 12
    • 0026002431 scopus 로고
    • Hydrogen peroxide cytotoxicity in LLC-PK1 cells; A role for iron
    • WALKER, P. D. & S. V. SHAH: Hydrogen peroxide cytotoxicity in LLC-PK1 cells; A role for iron. Kidney Int. 40: 891-898, 1991
    • (1991) Kidney Int. , vol.40 , pp. 891-898
    • Walker, P.D.1    Shah, S.V.2
  • 13
    • 0023002954 scopus 로고
    • The involvement of cellular ATP in receptor mediated internalization of epidermal growth factor and hormone-induced internalization of β-adrenergic receptors
    • HERTEL, C.; S. J. COULTER & J. P. PERKINS: The involvement of cellular ATP in receptor mediated internalization of epidermal growth factor and hormone-induced internalization of β-adrenergic receptors. J. Biol. Chem. 261: 5974-5980, 1986
    • (1986) J. Biol. Chem. , vol.261 , pp. 5974-5980
    • Hertel, C.1    Coulter, S.J.2    Perkins, J.P.3
  • 14
    • 0023919786 scopus 로고
    • Firefly luciferase luminescence assays using scintillation counters for quantitation in transfected mammalian cells
    • NGUYEN, V. T.; M. MORANGE & O. BENSAUDE: Firefly luciferase luminescence assays using scintillation counters for quantitation in transfected mammalian cells. Anal. Biochem. 171: 404-408, 1988
    • (1988) Anal. Biochem. , vol.171 , pp. 404-408
    • Nguyen, V.T.1    Morange, M.2    Bensaude, O.3
  • 15
    • 0028369668 scopus 로고
    • Intracelluylar hydrogen peroxide and superoxide anion detection in endothelial cells
    • CARTER, W. O.; P. K. NARAYANAN & J. P. ROBINSON: Intracelluylar hydrogen peroxide and superoxide anion detection in endothelial cells. J. Leukocyte Biol. 55: 253-258, 1994
    • (1994) J. Leukocyte Biol. , vol.55 , pp. 253-258
    • Carter, W.O.1    Narayanan, P.K.2    Robinson, J.P.3
  • 16
    • 0026712124 scopus 로고
    • Role of intracellular calsium in hydrogen peroxide-induced rejnal tubular cell injury
    • UEDA, N. & S. V. SHAH: Role of intracellular calsium in hydrogen peroxide-induced rejnal tubular cell injury. Am. J. Physiol. 263: F214-F221, 1992
    • (1992) Am. J. Physiol. , vol.263
    • Ueda, N.1    Shah, S.V.2
  • 17
    • 0023861035 scopus 로고
    • Energy thresholds that determine membrane integrity and injury in a renal epithelial cell line (LLC-PK1). Relationships to phospholipid degradation and unesterified fatty acid accumulation
    • VENKATACHALAM, M.; Y. J. PATEL, J. I. KREISBERG & J. M. WEINBERG: Energy thresholds that determine membrane integrity and injury in a renal epithelial cell line (LLC-PK1). Relationships to phospholipid degradation and unesterified fatty acid accumulation. J. Clin. Invest. 81: 745-758, 1988
    • (1988) J. Clin. Invest. , vol.81 , pp. 745-758
    • Venkatachalam, M.1    Patel, Y.J.2    Kreisberg, J.I.3    Weinberg, J.M.4
  • 18
    • 0025126555 scopus 로고
    • Free radicals and catalytic metal ions in human disease: An over view
    • HALLIWELL, B. & J. M. C. GUTTERIDGE: Free radicals and catalytic metal ions in human disease: an over view. Methods Enzymol. 186: 1-85, 1990
    • (1990) Methods Enzymol. , vol.186 , pp. 1-85
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 20
    • 0027328056 scopus 로고
    • Depletion of the miotochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF
    • SHULZE-OSTHOFF, K.; R. BEYAERT, V. VANDEVOORDE, G. HAEGEMAN & W. FIERS: Depletion of the miotochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF. EMBO J. 12: 3095-3104, 1993
    • (1993) EMBO J. , vol.12 , pp. 3095-3104
    • Shulze-Osthoff, K.1    Beyaert, R.2    Vandevoorde, V.3    Haegeman, G.4    Fiers, W.5
  • 21
    • 0030034283 scopus 로고    scopus 로고
    • Endonuclease induced DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells
    • HAGAR, H.; N. UEDA & S. V. SHAH: Endonuclease induced DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. Kidney Int. 49: 355-361, 1996
    • (1996) Kidney Int. , vol.49 , pp. 355-361
    • Hagar, H.1    Ueda, N.2    Shah, S.V.3
  • 22
    • 0021996572 scopus 로고
    • Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
    • TURRENS, J. F.; A. ALEXANDRE & A. L. LEHNINGER: Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria. Arch. Biochem. Biophys. 237: 408-414, 1985
    • (1985) Arch. Biochem. Biophys. , vol.237 , pp. 408-414
    • Turrens, J.F.1    Alexandre, A.2    Lehninger, A.L.3
  • 23
    • 0025358947 scopus 로고
    • The protonmotive Q cycle energy trunsduction by coupling of proton translocation to electron transfer by the cytochrome bcl complex
    • TRUMPOWER, B. L.: The protonmotive Q cycle energy trunsduction by coupling of proton translocation to electron transfer by the cytochrome bcl complex. J. Biol. Chem. 265: 11409-11412, 1990
    • (1990) J. Biol. Chem. , vol.265 , pp. 11409-11412
    • Trumpower, B.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.