Endonuclease induced DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells

Kidney International

Volumn 49, Issue 2, 1996, Pages 355-361

  Hagar, Hanan ^a   Ueda, Norishi ^a   Shah, Sudhir V ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMYCIN A1; ENDONUCLEASE;

ARTICLE; CELL CULTURE; CELL DAMAGE; CELL DEATH; CELL STRAIN LLC PK1; CHEMICAL INJURY; CONTROLLED STUDY; DNA DAMAGE; KIDNEY TUBULE CELL; KIDNEY TUBULE EPITHELIUM; PRIORITY JOURNAL;

EID: 0030034283     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1996.52     Document Type: Article

References (28)

1. KERR JFR, WYLLIE AH, CURRIE AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257, 1972
2. WEINBERG JM: The cell biology of ischemic renal injury. Kidney Int 39:476-500, 1991
3. BURKE TJ, SCHRIER RW: Pathophysiology of cell ischemia, in Diseases of the Kidney (vol 2), edited by SCHRIER RW, GOTTSCHALK C, Boston, Little Brown and Company, 1993, pp 1257-1286
4. WYLLIE AH, KERR JFK, CURRIE AR: Cell death: The significance of apoptosis. Int Rev Cytolol 68:251-306, 1980
5. SEARLE J, KERR JFR, BISHOP CJ: Necrosis and apoptosis: Distinct modes of cell death with fundamentally different significance. Pathol Ann 17:229-259, 1982
6. STELLER H: Mechanisms and genes of cellular suicide. Science 267: 1445-1449, 1995
7. THOMPSON CB: Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1462, 1995
8. COHEN JJ, DUKE RC: Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J Immunol 132:38-42, 1984
9. UEDA N, WALKER PD, HSU S-M, SHAH SV: Activation of a 15-kDa endonuclease in hypoxia/reoxygenation injury without morphologic features of apoptosis. Proc Natl Acacl Sci USA 92:7202-7206, 1995
10. 1). Relationships to phospholipid degradation and unesterifed fatty acid accumulation. J Clin Invest 81:745-758, 1988
11. MOLITORIS BA: New insights into the cell biology of ischemic acute renal failure. J Am Soc Nephrol 1:1263-1270, 1991
12. UEDA N, SHAH SV: Endonuclease-induced DNA damage and cell death in oxidant injury to renal tubular epithelial cells. J Clin Invest 90:2593-2597, 1992
13. BIRNBOIM HC, JEVCAK JJ: Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation. Cancer Res 41:1889-1892, 1981
14. HOCKENBERY D, NUNEZ G, MILLIMAN C, SCHREIBER RD, KORSMEYER SJ: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336, 1990
15. GAIDO ML, CIDLOWSKI JA: Identification, purification and characterization of a calcium-dependent endonuclease (NUC18) from apoptotic rat thymocytes. J Bio! Chem 266:18580-18585, 1991
16. ROSENTHAL AL, LACKS SA: Nuclease detection in SDS-polyacrylamide gel electrophoresis. Anal Biochem 80:76-90, 1977
17. BRADFORD MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, 1976
18. DOCTOR RB, MANDEL LJ: Minimal role of xanthine oxidase and oxygen free radicals in rat renal tubular reoxygenation injury. J Am Soc Nephrol 1:959-969, 1991
19. +-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion. J Clin Invest 88:462-469, 1991
20. NAKANE H, BALZARINI J, DE CLERCQ E, ONO K: Differential inhibition of various deoxyribonucleic acid polymerases by Evans blue and aurintricarhoxylic acid. Eur J Biochem 177:91-96, 1988
21. BABA M, SCHOLS D, PAUWELS R, BALZARINI J, DE CLERCQ E: Fuchsin acid selectively inhibits human immunodeficiency virus (HIV) replication in vitro. Biochem Biophys Res Commun 155:1404-1411, 1988
22. SCHUMER M, COLOMBEL MC, SAWCZUK IS, GOBE G, CONNOR J, O'TOOLE KM, OLSSON CA, WISE GJ, BUTTYAN R: Morphologic, biochemical, and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia. Am J Pathol 140:831-838, 1992
23. MILLER SB, MARTIN DR, KISSANE JM: Growth factors inhibit the apoptotic response to ischemic renal injury in rats. (abstract) J Am Soc Nephrol 5:904, 1994
24. NOGAE S, KOJI T, NAKANISHI Y, SAITO T, ABE K, NAKANE PK: Induction of apoptosis in ischemia-reperfusion kidney model: Appearance of DNA strand breaks and expression of FAS mRNA. (abstract) J Am Soc Nephrol 5:905, 1994
25. IWATA M, MYERSON D, TOROK-STORB B, ZAGER RA: An evaluation of renal tubular DNA laddering in response to oxygen deprivation and oxidant injury. J Am Soc Nephrol 5:1307-1313, 1994
26. ENRIGHT H, HEBBEL RP, NATH KA: Internucleosomal cleavage of DNA as the sole criterion for apoptosis may be artifactual. J Lab Clin Med 124:63-68, 1994
27. COHEN JJ, DUKE RC, FADOK VA, SELLINS KS: Apoptosis and programmed cell death in immunity. Ann Rev Immunol 10:267-293, 1992
28. ZAMZAMI N, MARCHETTI P, CASTEDO M. ZANIN C, VAYSSIERE J-L, PETIT PX, KROEMER G: Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J Exp Med 181:1661-1672, 1995