Expansion of CD57 and CD62L-CD45RA+ CD8 T lymphocytes correlates with reduced viral plasma RNA after primary HIV infection

AIDS

Volumn 13, Issue 8, 1999, Pages 891-899

  Lieberman, Judy ^a,e   Trimble, Linda A ^a   Friedman, Rachel S ^a   Lisziewicz, Julianna ^b,c   Lori, Franco ^b,c   Shankar, Premlata ^a   Jessen, Heiko ^d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c Jessen Praxis ^*  (Italy)

^d Jessen Praxis   (Germany)

^e CENTER FOR BLOOD RESEARCH   (United States)

Author keywords

CD38; CD57; CD8 T cells; Human immunodeficiency virus; Primary infection

Indexed keywords

CD38 ANTIGEN; CD45 ANTIGEN; CD57 ANTIGEN; CD8 ANTIGEN; CYTOTOXIC FACTOR; GRANZYME A; HLA DR ANTIGEN; PADGEM PROTEIN; VIRUS RNA;

ADULT; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; MEMORY CELL; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; VIREMIA; VIRUS LOAD;

ADOLESCENT; ADULT; ANTIGENS, CD45; ANTIGENS, CD57; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CD4 LYMPHOCYTE COUNT; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; FLOW CYTOMETRY; HIV INFECTIONS; HIV-1; HUMANS; L-SELECTIN; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; RNA, VIRAL; T-LYMPHOCYTE SUBSETS; VIRAL LOAD;

EID: 0032966304     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199905280-00004     Document Type: Article

References (52)

1. + lymphocytes as prognostic markers of HIV-1 infection. Ann Intern Med 1997, 126:946-954.
2. + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 1994, 68:6103-6110.
3. Koup RA, Safrit JT, Cao Y, et al. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 1994, 68:4650-4655.
4. McDougal JS, Mawle A, Cort SP, et al. Cellular tropism of the human retrovirus HTLV-III/LAV I: role of T cell activation and expression of the T4 antigen. J Immunol 1985, 135:3151-3162.
5. Folks TM, Justement J, Kinter A, Dinarello CA, Fauci AS. Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line. Science 1987, 238:800-802.
6. + T cells is a marker of poor prognosis in HIV infection: results of 6 years of follow-up. Cytometry 1996, 26:1-7.
7. + cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression. J Acquired Immune Defic Syndr Hum Retrovirol 1997, 16:83-92.
8. + lymphocyte percent: a useful immunological marker for monitoring HIV-1-infected patients. J Acquired Immune Defic Syndr Hum Retrovirol 1997, 14:158-162.
9. Ogg GS, Jin X, Bonhoeffer S, et al. Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA. Science 1998, 279:2103-2106.
10. Vanham G, Kestens L, Gigase P, et al. Evidence for circulating activated cytotoxic T cells in HIV-infected subjects before the onset of opportunistic infections. Clin Exp Immunol 1990, 82:3-9.
11. - cell population in the blood and lung of HIV-positive patients. J Acquired Immune Defic Syndr Hum Retrovirol 1993, 6:1194-1204.
12. + T cell populations in HIV disease and in anti-HIV immunity. Clin Exp Immunol 1993, 92:93-99.
13. + cytotoxic T cells express CD38 and HLA-DR antigens. J Immunol 1993, 150:3070-3079.
14. + T cells from HIV-infected persons. J Immunol 1994, 153:412-420.
15. + T lymphocytes. AIDS 1995, 9:561-566.
16. Cossarizza A, Ortolani C, Mussini C, et al. Massive activation of immune cells with an intact T cell repertoire in acute human immunodeficiency virus syndrome. J Infect Dis 1995, 172:105-112.
17. Roederer M, Dubs JG, Anderson MT, Raju PA, Herzenberg LA, Herzenberg LA. CD8 naive T cell counts decrease progressively in HIV-infected adults. J Clin Invest 1995, 95:2061-2066.
18. Bouscarat F, Levacher-Clergeot M, Dazza MC, et al. Correlation of CD8 lymphocyte activation with cellular viremia and plasma HIV RNA levels in asymptomatic patients infected by human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 1996, 12:17-24.
19. Roederer M, De Rosa S, Gerstein R, et al. 8 color, 10-parameter flow cytometry to elucidate complex leukocyte heterogeneity. Cytometry 1997, 29:328-339.
20. Clark SJ, Saag MS, Decker WD, et al. High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection. New Engl J Med 1991, 324:954-960.
21. Daar ES, Moudgil T, Meyer RD, Ho DD. Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection. New Engl J Med 1991, 324:961-964.
22. Beresford PJ, Kam CM, Powers JC, Lieberman J. Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them. Proc Natl Acad Sci U S A 1997, 94:9285-9290.
23. Fujiwara T, Oda K, Yokota S, Takatsuki A, Ikehara Y. Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum. J Biol Chem 1988, 263:18545-18552.
24. Garcia-Sanz JA, Velotti F, MacDonald HR, Masson D, Tschopp J, Nabholz M. Appearance of granule-associated molecules during activation of cytolytic T-lymphocyte precursors by defined stimuli. Immunology 1988, 64:129-134.
25. Moss PA, Rowland-Jones SL, Frodsham PM, et al. Persistent high frequency of human immunodeficiency virus-specific cytotoxic T cells in peripheral blood of infected donors. Proc Natl Acad Sci U S A 1995, 92:5773-5777.
26. Altman JD, Moss PAH, Goulder PJR, et al. Phenotypic analysis of antigen-specific T lymphocytes. Science 1996, 274:94-96.
27. + T cells in acute infectious mononucleosis. Nature Med 1996, 2:906-911.
28. + T cells during an acute virus infection. Immunity 1998, 8:167-175.
29. Murali-Krishna K, Altman JD, Suresh M, et al. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity 1998, 8:177-187.
30. + memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals. Proc Natl Acad Sci U S A 1990, 87:6058-6062.
31. Roederer M, De Rosa SC, Watanabe N, Herzenberg LA. Dynamics of fine T-cell subsets during HIV disease and after thymic ablation by mediastinal irradiation. Semin Immunol 1997, 9:389-396.
32. + lymphocytes can control HIV infection in vitro by suppressing vírus replication. Science 1986, 234:1563-1566.
33. Walker BD, Chakrabarti S, Moss B, et al. HIV-specific cytotoxic T lymphocytes in seropositive individuals. Nature 1987, 328:345-348.
34. Plata F, Autran B, Martins LP, et al. AIDS virus-specific cytotoxic T lymphocytes in lung disorders. Nature 1987, 328:348-351.
35. + T cells. Science 1995, 270:1811-1815.
36. Baier M, Werner A, Bannert N, Metzner K, Kurth R. HIV suppression by interleukin-16. Nature 1995, 378:563.
37. Hoffenbach A, Langlade-Demoyen P, Dadaglio G, et al. Unusually high frequencies of HIV-specific cytotoxic T lymphocytes in humans. J Immunol 1989, 142:452-462.
38. Riviere Y, McChesney MB, Porrot F, et al. Gag-specific cytotoxic responses to HIV type 1 are associated with a decreased risk of progression to AIDS-related complex or AIDS. AIDS Res Hum Retroviruses 1995, 11:903-907.
39. Kourlis AP, Ibegbu C, Nahmias AJ, et al. Early progression of disease in HIV-infected infants with thymus dysfunction. N Engl J Med 1996, 335:1431-1436.
40. Autran B, Mayaud CM, Raphael M, et al. Evidence for a cytotoxic T-lymphocyte alveolitis in human immunodeficiency virus-infected patients. AIDS 1988, 2:179-183.
41. Sethi KK, Naher H, Stroehmann I. Phenotypic heterogeneity of cerebrospinal fluid-derived HIV-specific and HLA-restricted cytotoxic T-cell clones. Nature 1988, 335:178-181.
42. Zinkernagel RM, Hengartner H. T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS. Immunol Today 1994, 15:262-268.
43. Shubinsky G, Schlesinger M. The CD38 lymphocyte differentiation marker: new insight into its ectoenzymatic activity and its role as a signal transducer. Immunity 1997, 7:315-324.
44. Deaglio S, Morra M, Mallone R, et al. Human CD38 (ADP-ribosyl cyclase) is a counter-receptor of CD31, an Ig super-family member. J Immunol 1998, 160:395-402.
45. + T cell homeostasis and function in advanced HIV disease. Science 1997, 277:112-116.
46. + T cell phenotype correlates with anti-HIV activity and asymptomatic clinical status. Clin Immunol Immunopathol 1993, 69:106-116.
47. + T cells. J Exp Med 1997, 186:1407-1418.
48. + cell suppression of HIV replication. J Immunol 1997, 159:5123-5131.
49. + lymphocytes on cell-mediated cytotoxicity: characterization of suppressor factor. Comptes Rendus de l'Academie des Sciences - Serie lii, Sciences de la Vie 1991, 312:197-202.
50. +/CD57 cells and apoptosis suppress T-cell functions in multiple myeloma. Br J Haematol 1998, 100:469-477.
51. + lymphocytes from AIDS patients inhibits T cell cytotoxicity. Eur J Immunol 1991, 21:737-741.
52. +) T cells in normal, healthy individuals specifically suppress the generation of cytotoxic T lymphocytes to Epstein-Barr virus-transformed B cell lines. Eur J Immunol 1994, 24:2903-2909.