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Volumn 33, Issue 3, 1997, Pages 471-478

Biochemical mechanisms of interferon modulation of 5-fluorouracil activity in colon cancer cells

Author keywords

5 fluorouracil; colon cancer; interferons

Indexed keywords

ALPHA INTERFERON; ALPHA2A INTERFERON; FLUOROURACIL; GAMMA INTERFERON; THYMIDYLATE SYNTHASE;

EID: 0031105022     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(97)89024-7     Document Type: Article
Times cited : (43)

References (46)
  • 1
    • 0023718558 scopus 로고
    • Interferon effects upon the adenocarcinoma 38 and HL-60 lines: Antiproliferative responses and synergistic interactions with halogenated pyrimidine antimetabolites
    • Elias L, Crissman HA. Interferon effects upon the adenocarcinoma 38 and HL-60 lines: antiproliferative responses and synergistic interactions with halogenated pyrimidine antimetabolites. Cancer Res. 48:1988;4868-4873.
    • (1988) Cancer Res , vol.48 , pp. 4868-4873
    • Elias, L.1    Crissman, H.A.2
  • 2
    • 0025043811 scopus 로고
    • Interaction of gamma-interferon and 5-fluorouracil in the H630 human colon carcinoma cell line
    • Chu E, Zinn S, Boarman D, Allegra CJ. Interaction of gamma-interferon and 5-fluorouracil in the H630 human colon carcinoma cell line. Cancer Res. 50:1990;5834-5840.
    • (1990) Cancer Res , vol.50 , pp. 5834-5840
    • Chu, E.1    Zinn, S.2    Boarman, D.3    Allegra, C.J.4
  • 3
    • 0025945855 scopus 로고
    • Phase-II trial of fluorouracil and recombinant interferon alfa-2a in patients with advanced colorectal carcinoma - An Eastern Cooperative Oncology Group study
    • Wadler S, Lembersky B, Atkins M, Kirkwood J, Petrelli N. Phase-II trial of fluorouracil and recombinant interferon alfa-2a in patients with advanced colorectal carcinoma - an Eastern Cooperative Oncology Group study. J Clin Oncol. 9:1991;1806-1810.
    • (1991) J Clin Oncol , vol.9 , pp. 1806-1810
    • Wadler, S.1    Lembersky, B.2    Atkins, M.3    Kirkwood, J.4    Petrelli, N.5
  • 4
    • 0027326441 scopus 로고
    • Phase II study of fluorouracil leucovorin and interferon alfa-2a in metastatic colorectal carcinoma
    • Grem JL, Jordan D, Robson ME, et al. Phase II study of fluorouracil leucovorin and interferon alfa-2a in metastatic colorectal carcinoma. J Clin Oncol. 11:1993;1737-1745.
    • (1993) J Clin Oncol , vol.11 , pp. 1737-1745
    • Grem, J.L.1    Jordan, D.2    Robson, M.E.3
  • 5
    • 0028134952 scopus 로고
    • Biologic agents as biochemical modulators: Pharmacologic basis for the interaction of cytoxic chemotherapeutic drugs and interferon
    • Wadler S, Schwartz EL. Biologic agents as biochemical modulators: pharmacologic basis for the interaction of cytoxic chemotherapeutic drugs and interferon. Cancer Chemother Pharmacol. 35:1994;21-30.
    • (1994) Cancer Chemother Pharmacol , vol.35 , pp. 21-30
    • Wadler, S.1    Schwartz, E.L.2
  • 6
    • 0028956096 scopus 로고
    • Phase III randomized study of two fluorouracil combinations with either IFN alfa-2a or leucovorin for advanced colorectal cancer
    • Corfu-A Study Group
    • Kocha W. Phase III randomized study of two fluorouracil combinations with either IFN alfa-2a or leucovorin for advanced colorectal cancer. Corfu-A Study Group J Clin Oncol. 13:1995;921-928.
    • (1995) J Clin Oncol , vol.13 , pp. 921-928
    • Kocha, W.1
  • 7
    • 0029016021 scopus 로고
    • Royal Marsden phase III trial of fluorouracil with or without interferon alfa-2b in advanced colorectal carcinoma
    • Hill M, Norman A, Cunningham D, et al. Royal Marsden phase III trial of fluorouracil with or without interferon alfa-2b in advanced colorectal carcinoma. J Clin Oncol. 13:1995;1297-1302.
    • (1995) J Clin Oncol , vol.13 , pp. 1297-1302
    • Hill, M.1    Norman, A.2    Cunningham, D.3
  • 8
    • 0029131435 scopus 로고
    • Impact of protracted venous infusion fluorouracil with or without interferon alfa-2b on tumor response, survival, and quality of life in advanced colorectal cancer
    • Hill M, Norman A, Cunningham D, et al. Impact of protracted venous infusion fluorouracil with or without interferon alfa-2b on tumor response, survival, and quality of life in advanced colorectal cancer. J Clin Oncol. 13:1995;2317-2333.
    • (1995) J Clin Oncol , vol.13 , pp. 2317-2333
    • Hill, M.1    Norman, A.2    Cunningham, D.3
  • 9
    • 0026606649 scopus 로고
    • Type I interferon resistance in a colorectal cancer cell line is associated with a more aggressive phenotype in vivo
    • Toth CA, Thomas P. Type I interferon resistance in a colorectal cancer cell line is associated with a more aggressive phenotype in vivo. Br J Cancer. 65:1992;365-368.
    • (1992) Br J Cancer , vol.65 , pp. 365-368
    • Toth, C.A.1    Thomas, P.2
  • 10
    • 0019379907 scopus 로고
    • Biochemical factors affecting the tightness of 5-fluorodeoxyuridylate binding to human thymidylate synthase
    • Lockshin A, Danenberg PV. Biochemical factors affecting the tightness of 5-fluorodeoxyuridylate binding to human thymidylate synthase. Biochem Pharmacol. 30:1981;247-257.
    • (1981) Biochem Pharmacol , vol.30 , pp. 247-257
    • Lockshin, A.1    Danenberg, P.V.2
  • 11
    • 0024414582 scopus 로고
    • Interferon effects upon fluorouracil metabolism by HL-60 cells
    • Elias L, Sandoval JM. Interferon effects upon fluorouracil metabolism by HL-60 cells. Biochem Biophys Res Commun. 163:1989;867-874.
    • (1989) Biochem Biophys Res Commun , vol.163 , pp. 867-874
    • Elias, L.1    Sandoval, J.M.2
  • 12
    • 0026600296 scopus 로고
    • Stimulation of 5-fluorouracil metabolic activation by interferon-α in human colon carcinoma cell lines
    • Schwartz E, Hoffman M, O'Connor CJ, Wadler S. Stimulation of 5-fluorouracil metabolic activation by interferon-α in human colon carcinoma cell lines. Biochem Biophys Res Commun. 3:1992;1232-1239.
    • (1992) Biochem Biophys Res Commun , vol.3 , pp. 1232-1239
    • Schwartz, E.1    Hoffman, M.2    O'Connor, C.J.3    Wadler, S.4
  • 13
    • 0025848306 scopus 로고
    • Interaction between 5-fluorouracil, [6RS]leucovorin, and recombinant human interferon-α2a in cultured colon adenocarcinoma cells
    • Houghton JA, Adkins DA, Rahman A, Houghton PJ. Interaction between 5-fluorouracil, [6RS]leucovorin, and recombinant human interferon-α2a in cultured colon adenocarcinoma cells. Cancer Commun. 3:1991;225-231.
    • (1991) Cancer Commun , vol.3 , pp. 225-231
    • Houghton, J.A.1    Adkins, D.A.2    Rahman, A.3    Houghton, P.J.4
  • 14
    • 0027363496 scopus 로고
    • Combined modulation by leucovorin and α-2a interferon of fluoropyrimidine mediated growth inhibition
    • Sinnige HAM, Timmer-Boscha H, Peters GJ, De Vries EGE, Mulder NH. Combined modulation by leucovorin and α-2a interferon of fluoropyrimidine mediated growth inhibition. Anticancer Res. 13:1993;1335-1340.
    • (1993) Anticancer Res , vol.13 , pp. 1335-1340
    • Sinnige, H.A.M.1    Timmer-Boscha, H.2    Peters, G.J.3    De Vries, E.G.E.4    Mulder, N.H.5
  • 15
    • 0027817576 scopus 로고
    • Locus of the interaction among 5-fluorouracil, leucovorin and interferon-α-2a in colon carcinoma cells
    • Houghton JA, Morton CL, Atkins DA, Rahman A. Locus of the interaction among 5-fluorouracil, leucovorin and interferon-α-2a in colon carcinoma cells. Cancer Res. 53:1993;4243-4250.
    • (1993) Cancer Res , vol.53 , pp. 4243-4250
    • Houghton, J.A.1    Morton, C.L.2    Atkins, D.A.3    Rahman, A.4
  • 16
    • 0028307399 scopus 로고
    • Inhibition of dihydropyrimidine dehydrogenase by α-interferon: Experimental data on human tumor cell lines
    • Milano G, Fischel JL, Etienne MC, et al. Inhibition of dihydropyrimidine dehydrogenase by α-interferon: experimental data on human tumor cell lines. Cancer Chemother Pharmacol. 34:1994;147-152.
    • (1994) Cancer Chemother Pharmacol , vol.34 , pp. 147-152
    • Milano, G.1    Fischel, J.L.2    Etienne, M.C.3
  • 17
    • 0027509829 scopus 로고
    • Cytokines induce uridine phosphorylase in mouse colon 26 carcinoma cells and make the cells more susceptible to 5′-deoxyfluorouridine
    • Eda H, Fujimoto K, Watanabe S, et al. Cytokines induce uridine phosphorylase in mouse colon 26 carcinoma cells and make the cells more susceptible to 5′-deoxyfluorouridine. Jpn J Cancer Res. 84:1993;341-347.
    • (1993) Jpn J Cancer Res , vol.84 , pp. 341-347
    • Eda, H.1    Fujimoto, K.2    Watanabe, S.3
  • 18
    • 0027313603 scopus 로고
    • Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5′-deoxy-5-fluorouridine
    • Eda H, Fujimoto K, Watanabe S, et al. Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5′-deoxy-5-fluorouridine. Cancer Chemother Pharmacol. 32:1993;333-338.
    • (1993) Cancer Chemother Pharmacol , vol.32 , pp. 333-338
    • Eda, H.1    Fujimoto, K.2    Watanabe, S.3
  • 19
    • 0027416220 scopus 로고
    • Regulation of thymidylate synthase in human colon cancer cells treated with 5-fluorouracil and interferon-gamma
    • Chu E, Koeller DM, Johnston PG, Zinn S, Allegra CJ. Regulation of thymidylate synthase in human colon cancer cells treated with 5-fluorouracil and interferon-gamma. Mol Pharmacol. 43:1993;527-533.
    • (1993) Mol Pharmacol , vol.43 , pp. 527-533
    • Chu, E.1    Koeller, D.M.2    Johnston, P.G.3    Zinn, S.4    Allegra, C.J.5
  • 20
    • 0025990937 scopus 로고
    • Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase
    • Chu E, Koeller DM, Casey JL, et al. Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase. Proc Natl Acad Sci USA. 88:1991;8977-8981.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8977-8981
    • Chu, E.1    Koeller, D.M.2    Casey, J.L.3
  • 21
    • 0023937398 scopus 로고
    • Possible link between intrinsic drug resistance of colon tumors an a detoxification mechanism of intestinal cells
    • Klohs WD, Steinkampf RW. Possible link between intrinsic drug resistance of colon tumors an a detoxification mechanism of intestinal cells. Cancer Res. 48:1988;3025-3030.
    • (1988) Cancer Res , vol.48 , pp. 3025-3030
    • Klohs, W.D.1    Steinkampf, R.W.2
  • 22
    • 0026547072 scopus 로고
    • In vitro and in vivo studies on the combination of brequinar sodium (DUP-785; NSC 368390) with 5-fluorouracil; Effects of uridine
    • Peters GJ, Kraal I, Pinedo HM. In vitro and in vivo studies on the combination of brequinar sodium (DUP-785; NSC 368390) with 5-fluorouracil; effects of uridine. Br J Cancer. 65:1992;229-234.
    • (1992) Br J Cancer , vol.65 , pp. 229-234
    • Peters, G.J.1    Kraal, I.2    Pinedo, H.M.3
  • 23
    • 0018759548 scopus 로고
    • Characterization of WIDR: A human colon carcinoma cell line
    • Noguchi PR, Wallace J, Johnson EM, et al. Characterization of WIDR: a human colon carcinoma cell line. In Vitro. 15:1979;401-408.
    • (1979) In Vitro , vol.15 , pp. 401-408
    • Noguchi, P.R.1    Wallace, J.2    Johnson, E.M.3
  • 25
    • 0028848276 scopus 로고
    • Screening of colon tumor cells and tissues for folylpolyglutamate synthetase activity
    • Van der Wilt CL, Cloos J, De Jong M, Pinedo HM, Peters GJ. Screening of colon tumor cells and tissues for folylpolyglutamate synthetase activity. Oncol Res. 7:1995;317-321.
    • (1995) Oncol Res , vol.7 , pp. 317-321
    • Van Der Wilt, C.L.1    Cloos, J.2    De Jong, M.3    Pinedo, H.M.4    Peters, G.J.5
  • 26
    • 0025341331 scopus 로고
    • New colorimetric assay for anticancer-drug screening
    • Skehan P, Storeng R, Scudiero D, et al. New colorimetric assay for anticancer-drug screening. J Natl Cancer Inst. 82:1990;107-112.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 107-112
    • Skehan, P.1    Storeng, R.2    Scudiero, D.3
  • 27
    • 0025878872 scopus 로고
    • Comparison of the sulphorhodamine B protein and tetrazolium (MMT) assays for in vitro chemosensitivity testing
    • Keepers YPAM, Pizao PE, Peters GJ, Van Ark-Otte J, Winograd B. Comparison of the sulphorhodamine B protein and tetrazolium (MMT) assays for in vitro chemosensitivity testing. Eur J Cancer. 27:1991;897-900.
    • (1991) Eur J Cancer , vol.27 , pp. 897-900
    • Keepers, Y.P.A.M.1    Pizao, P.E.2    Peters, G.J.3    Van Ark-Otte, J.4    Winograd, B.5
  • 28
    • 0027287554 scopus 로고
    • Transformation of mouse fibroblasts with the oncogenes H-ras or trk is associated with pronounced changes in drug sensitivity and metabolism
    • Peters GJ, Wets M, Keepers YPAM, et al. Transformation of mouse fibroblasts with the oncogenes H-ras or trk is associated with pronounced changes in drug sensitivity and metabolism. Int J Cancer. 54:1993;450-455.
    • (1993) Int J Cancer , vol.54 , pp. 450-455
    • Peters, G.J.1    Wets, M.2    Keepers, Y.P.A.M.3
  • 29
    • 0027440968 scopus 로고
    • In vitro antitumor activity of cis- and trans-5,6-dihydro-6-alkoxy-uracils; Effect on thymidylate synthesis
    • Van der Wilt CL, Visser GWM, Braakhuis BJM, et al. In vitro antitumor activity of cis- and trans-5,6-dihydro-6-alkoxy-uracils; effect on thymidylate synthesis. Br J Cancer. 68:1993;702-707.
    • (1993) Br J Cancer , vol.68 , pp. 702-707
    • Van Der Wilt, C.L.1    Visser, G.W.M.2    Braakhuis, B.J.M.3
  • 30
    • 0026788343 scopus 로고
    • Elevation of thymidylate synthase after 5-fluorouracil in murine tumors is prevented by the addition of folinic acid
    • Van der Wilt CL, Pinedo HM, Smid K, Peters GJ. Elevation of thymidylate synthase after 5-fluorouracil in murine tumors is prevented by the addition of folinic acid. Cancer Res. 52:1992;4922-4928.
    • (1992) Cancer Res , vol.52 , pp. 4922-4928
    • Van Der Wilt, C.L.1    Pinedo, H.M.2    Smid, K.3    Peters, G.J.4
  • 31
    • 0029039255 scopus 로고
    • Addition of leucovorin in modulation of 5-fluorouracil with methotrexate: Potentiating or reversing effect?
    • Van der Wilt CL, Braakhuis BJM, Pinedo HM, De Jong M, Smid K, Peters GJ. Addition of leucovorin in modulation of 5-fluorouracil with methotrexate: potentiating or reversing effect? Int J Cancer. 61:1995;672-678.
    • (1995) Int J Cancer , vol.61 , pp. 672-678
    • Van Der Wilt, C.L.1    Braakhuis, B.J.M.2    Pinedo, H.M.3    De Jong, M.4    Smid, K.5    Peters, G.J.6
  • 32
    • 0019476174 scopus 로고
    • Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation
    • Birnboim HC, Jevcak JJ. Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation. Cancer Res. 41:1981;1889-1892.
    • (1981) Cancer Res , vol.41 , pp. 1889-1892
    • Birnboim, H.C.1    Jevcak, J.J.2
  • 36
    • 0011251981 scopus 로고
    • Measurement of human thymidylate synthase (hTS) in cell lines using ELISA
    • Aherne GW, Hardcastle A, Newton R. Measurement of human thymidylate synthase (hTS) in cell lines using ELISA. Ann Oncol. 3:(Suppl. 1):1992;77.
    • (1992) Ann Oncol , vol.3 , Issue.SUPPL. 1 , pp. 77
    • Aherne, G.W.1    Hardcastle, A.2    Newton, R.3
  • 37
    • 0025776824 scopus 로고
    • The effects of gamma-interferon with 5-fluorouracil and 5-fluoro-2′-deoxyuridine on proliferation and antigen expression in a panel of human colorectal cancer cell lines
    • Maas IWHM, Boven E, Pinedo HM, Schlüper HMM, Haisma HJ. The effects of gamma-interferon with 5-fluorouracil and 5-fluoro-2′-deoxyuridine on proliferation and antigen expression in a panel of human colorectal cancer cell lines. Int J Cancer. 48:1991;749-756.
    • (1991) Int J Cancer , vol.48 , pp. 749-756
    • Maas, I.W.H.M.1    Boven, E.2    Pinedo, H.M.3    Schlüper, H.M.M.4    Haisma, H.J.5
  • 38
    • 0022226321 scopus 로고
    • Abrogation of species specificity for activation of tumordical properties in macrophages by recombinant mouse or human interferon-gamma encapsulated in liposomes
    • Fidler IJ, Fogler WE, Kleinerman ES, et al. Abrogation of species specificity for activation of tumordical properties in macrophages by recombinant mouse or human interferon-gamma encapsulated in liposomes. J Immunol. 135:1985;4289-4296.
    • (1985) J Immunol , vol.135 , pp. 4289-4296
    • Fidler, I.J.1    Fogler, W.E.2    Kleinerman, E.S.3
  • 39
    • 0028265392 scopus 로고
    • New targets for pyrimidine antimetabolites for the treatment of solid tumors: I. Thymidylate synthase
    • Van der Wilt CL, Peters GJ. New targets for pyrimidine antimetabolites for the treatment of solid tumors: I. Thymidylate synthase. Pharmacy World & Sci. 16:1994;84-103.
    • (1994) Pharmacy World & Sci , vol.16 , pp. 84-103
    • Van Der Wilt, C.L.1    Peters, G.J.2
  • 41
    • 0028210793 scopus 로고
    • Potentiation of antitumor activity of 5-fluorouracil in colon carcinoma cells by the combination of interferon and deoxyribonucleosides results from complementary effects on thymidine phosphorylase
    • Schwartz EL, Baptiste N, O'Connor CJ, Wadler S, Otter BA. Potentiation of antitumor activity of 5-fluorouracil in colon carcinoma cells by the combination of interferon and deoxyribonucleosides results from complementary effects on thymidine phosphorylase. Cancer Res. 54:1994;1472-1478.
    • (1994) Cancer Res , vol.54 , pp. 1472-1478
    • Schwartz, E.L.1    Baptiste, N.2    O'Connor, C.J.3    Wadler, S.4    Otter, B.A.5
  • 43
    • 0026795489 scopus 로고
    • Immunological quantification of thymidylate synthase using the monoclonal antibody TS106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines
    • Johnston PG, Drake JC, Treperl J, Allegra CJ. Immunological quantification of thymidylate synthase using the monoclonal antibody TS106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines. Cancer Res. 52:1992;4306-4312.
    • (1992) Cancer Res , vol.52 , pp. 4306-4312
    • Johnston, P.G.1    Drake, J.C.2    Treperl, J.3    Allegra, C.J.4
  • 44
    • 0029021602 scopus 로고
    • Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells
    • Pestalozzi BC, McGinn CJ, Kinsella TJ, et al. Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells. Br J Cancer. 71:1995;1151-1157.
    • (1995) Br J Cancer , vol.71 , pp. 1151-1157
    • Pestalozzi, B.C.1    McGinn, C.J.2    Kinsella, T.J.3
  • 45
    • 0011221080 scopus 로고
    • Inhibition of mammalial DNA polymerase by recombinant α-interferon
    • Tanaka M, Kimura K, Yoshida S. Inhibition of mammalial DNA polymerase by recombinant α-interferon. Cancer Res. 47:1987;107-112.
    • (1987) Cancer Res , vol.47 , pp. 107-112
    • Tanaka, M.1    Kimura, K.2    Yoshida, S.3
  • 46
    • 0029823120 scopus 로고    scopus 로고
    • Effect of interferon on 5-fluorouracil induced perturbations in pools of deoxynucleotide triphosphates and DNA strand breaks
    • Wadler S, Horowitz R, Mao X, Schwartz EL. Effect of interferon on 5-fluorouracil induced perturbations in pools of deoxynucleotide triphosphates and DNA strand breaks. Cancer Chemother Pharmacol. 38:1996;529-535.
    • (1996) Cancer Chemother Pharmacol , vol.38 , pp. 529-535
    • Wadler, S.1    Horowitz, R.2    Mao, X.3    Schwartz, E.L.4


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