Human brain activation under controlled thermal stimulation and habituation to noxious heat: An fMRI study

Magnetic Resonance in Medicine

Volumn 41, Issue 5, 1999, Pages 1044-1057

  Becerra, Lino R ^a   Breiter, Hans C ^a   Stojanovic, Milan ^a   Fishman, Scott ^a   Edwards, Annabel ^a   Comite, Alison R ^a   Gonzalez, R Gilberto ^a   Borsook, David ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

fMRI; Heat; Pain; Peltier thermode

Indexed keywords

ACTIVATION ANALYSIS; BRAIN; CHEMICAL ACTIVATION; HEATING; MAGNETIC RESONANCE IMAGING;

FMRI; FUNCTIONAL MAGNETIC RESONANCE IMAGING; PAIN; PELTIER; POSITIVE SIGNALS; SOMATOSENSORY CORTEX; SUPPLEMENTARY MOTOR AREAS; THERMAL STIMULATION;

FUNCTIONAL NEUROIMAGING;

ADULT; ARTICLE; BRAIN; CINGULATE GYRUS; HABITUATION; HEAT; HUMAN; HUMAN EXPERIMENT; MALE; NOCICEPTION; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PAIN; PSYCHOPHYSIOLOGY; SENSORIMOTOR CORTEX; SENSORY STIMULATION;

EID: 0032953639     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-2594(199905)41:5<1044::AID-MRM25>3.0.CO;2-M     Document Type: Article

References (49)

1. Breiter H, Etcoff NL, Whalen PJ, Kennedy WA, Rauch SL, Buckner RL, Strauss MM, Hyman SE, Rosen BR. Response and habituation of the human amygdala during visual processing of facial expression. Neuron 1996;17:875-887.
2. Davis KD, Taylor SJ, Crawley AP, Wood ML, Mikulis DJ. Functional MRI of pain- and attention-related activations in the human cingulate cortex. J Neurophysiol 1997;77:3370-3380.
3. Davis KD, Kwan CL, Crawley AP, Mikulis DJ. Functional MRI study of thalamic and cortical activations evoked by cutaneous heat, cold, and tactile stimuli. J Neurophysiol 1998;80:1533-1546.
4. Lamotte RH, Campbell JN. Comparison of responses of warm and nociceptive C-fiber afferents in monkey with human judgments of thermal pain. J Neurophysiol 1978;41:509-528.
5. Svensson P, Minoshima S, Beydoun A, Morrow TJ, Casey KL. Cerebral processing of acute skin and muscle pain in humans. J Neurophysiol 1997;78:450-460.
6. Casey KL, Minoshima S, Berger KL, Kloeppe RA, Morrow TJ, Frey KA. Positron emission tomographic analysis of cerebral structures activated specifically by repetitive noxious heat stimuli. J Neurophysiol 1994;71: 802-807.
7. Craig AD, Reiman EM, Evans A, Bushnell MC. Functional imaging of an illusion of pain. Nature 1996;384:258-260.
8. Jones AK, Brown DW, Friston KJ, Qi LY, Frackowizk RS. Cortical and subcortical localization of response to pain in man using positron emission tomography, Proc R Soc Lond B 1991;244:39-44.
9. Moiniche S, Dahl JB, Kehlet H. Time course of primary and secondary hyperalgesia after heat injury to the skin. Br J Anaesth 1993;71:201-205.
10. LaMotte RH, Thalhammer JG, Torebjork HE, Robinson CJ. Peripheral neural mechanisms of cutaneous hyperalgesia following mild injury by heat. J Neurosci 1982;2:765-781.
11. Talbot JD, Marret S, Evans AC, Meyer E, Bushnell MC, Duncan GH. Multiple representations of pain in human cerebral cortex. Science 1991;251:1355-1358.
12. Coghill RC, Talbot JD, Evans AC, Meyer E, Gjedde A, Bushnell MC, Duncan GH. Distributed processing of pain and vibration by the human by the human brain. J Neurosci 1994;14:4095-4108.
13. Drefin R, Urca G. Spatial summation of heat pain: a reassessment. Pain 1996;66:23-29.
14. LaMotte RH, Torebjork HE, Robinson CJ, Thalhammer JG. Time-intensity profiles of cutaneous pain in normal and hyperalgesic skin: a comparison with C-fiber nociceptor activities in monkey and human. J Neurophysiol 1984;51:1434-1450.
15. Price DD, Hu JW, Dubner R, Gracely RH. Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses. Pain 1977;3:57-68.
16. Melzack R. The McGill questionnaire: major properties and scoring methods. Pain 1975;1:277-299.
17. Talairach J, Tournoux P. Co-planar stereotaxic atlas of the human brain. New York: Thieme Medical Publishers, 1988.
18. Jiang A, Kennedy DN, Baker JR, Weisskoff RM, Tootell RBH, Woods RP, Benson RR, Kwong KK, Brady TJ, Rosen BR, Belliveau JW. Motion detection and correction in functional MR imaging. Hum Brain Mapping 1995;3:1-12.
19. Bates JS, Meyer JW, Makris N, Kennedy DN, Belliveau JW, Caviness VS. Parcellation of subcortical gray matter structures in the human brain: a morphometric tool with functional applications. Neuroimage 1996;3: S137 (Abstract).
20. Breiter HC, Rauch SL, Kwong KK, Baker JR, Weisskoff RM, Kennedy DN, Makris N, Berke JD, Goodman JM, Kantor HL, Gastfriend DR, Riorden JP, Matthew RT, Rosen BR, Hyman SE. Acute effects of cocaine on human brain activity and emotion. Neuron 1997;19:591-611.
21. Iadarola MJ, Max MB, Herman KF, Byas-Smith MG, Coghill RC, Gracely RH, Bennett GJ. Unilateral decrease in thalamic activity observed with positron emission tomography in patients with chronic neuropathic pain. Pain 1995;63:55-64.
22. Ojemann JG, McKinstry RC, Conturo TE, Snyder AZ, Akbudak E, Buckner RL, Grubb RL, Raichle ME. Negative functional MRI signals and models of blood flow and oxygen metabolism. Neurosci Abstr 1996;22:1105 (Abstract).
23. Malonek D, Grinvald A. Interactions between electrical activity and cortical microcirculation revealed by imaging spectroscopy: implications for functional brain mapping. Science 1996;272:551-554.
24. Breiter HC, Rauch SL, Kwong KK, Baker JR, Weisskoff RM, Kennedy DN, Kendrick AD, Davis TL, Jiang A, Cohen MS, et al. Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder. Arch Gen Psychiatry 1996;53:595-606.
25. Hsieh JC, Belfrage M, Stone-Elander S, Hansson P, Ingvar M. Central representation of chronic ongoing neuropathic pain studied by positron emission tomography. Pain 1995;63:225-236.
26. Ryding E, Eriksson MBE, Rosen I, Ingvar DH. Regional cerebral blood flow (rCBF) in man during perception of radiant warmth and heat pain. Pain 1985;22:353-352.
27. Rainville P, Duncan GH, Price DD, Carrier B, Bushnell MC. Pain encoded in human anterior cingulate but not somatosensory cortex. Science 1997;277:968-971.
28. Vogt BA, Derbyshire S, Jones AK. Pain processing in four regions of human cingulate cortex localized with co-registered PET and MR imaging. Eur J Neurosci 1996;8:1461-1473.
29. Casey KL, Minoshima S, Morrow TJ, Koeppe RA. Comparison of human cerebral activation patterns during cutaneous warmth, heat pain, and deep cold pain. J Neurophysiol 1996;76:571-581.
30. Lenz FA, Gracely RH, Romanoski AJ, Hope EJ, Rowland LH, Dougherty PM. Stimulation in the human somatosensory thalamus can reproduce both the affective and sensory dimensions of previously experienced pain. Nature Med 1995;1:910.
31. Decavel C, Van den Pol AN. GABA: a dominant neurotransmitter in the hypothalamus. J Comp Neurol 1990;302:1019-1037.
32. Craig AD, Bushnell MC, Zhang ET, Blomqvist A. A thalamic nucleus specific for pain and temperature sensation. Nature 1994;372:770-773.
33. Vogt BA, Finch DM, Olson CR. Functional heterogeneity in cingulate cortex: the anterior executive and posterior evaluative regions. Cereb Cortex 1992;2:435-443.
34. Maguire EA, Frith CD, Burgess N, Donnett JG, O'Keefe J. Knowing where things are parahippocampal involvement in encoding object locations in virtual large-scale space. J Cogn Neursci 1998;10:61-76.
35. Van Horn JD, Ellmore TM, Esposito G, Berman KF. Mapping voxel-based statistical power on parametric images. Neuroimage 1998;7:97-107.
36. Dafny N, Dong WQ, Prieto-Gomez C, Reyes-Vasquez C, Stanford J, Qiao JT. Lateral hypothalamus: site involved in pain modulation. Neuroscience 1996;70:449-460.
37. Manning BH, Mayer DJ. The central nucleus of the amygdala contributes to the production of morphine antinociception in the formalin test. J Neurosci 1995;15:8199-8213.
38. Cunningham ET, Sawchenko PE. Reflex control of magnocellular vasopressin and oxytocin secretion. Trends Neurosci 1991;14:406-411.
39. Swaab DF, Hofman MA, Lucassen PJ, Purba JS, Raadsheer FC, Van de Nes JA. Functional neuroanatomy and neuropathology of the human hypothalamus. Anat Embryol 1993;187:317-330.
40. Sawchenko PE, Brown ER, Chan RK, Ericsson A, Li HY, Kovacs KJ. The paraventricular nucleus of the hypothalamus and the functional neuroanatomy of visceromotor responses to stress. Prog Brain Res 1996;107: 201-222.
41. Gallagher M, Holland PC. The amygdala complex: multiple roles in associative learning and attention. Proc Natl Acad Sci USA 1994;91: 11171-11176.
42. Hsieh JC, Stahle-Backdahl M, Hagermark O, Stone-Elander S, Rosenquist G, Ingvar M. Traumatic nociceptive pain activates the hypothalamus and periaqueductal gray: a positron emission tomography study. Pain 1996;64:303-314.
43. Rosen SD, Paulesu E, Frith CD, Frackowiak RS, Davies GJ, Jones T, Camici PG. Central nervous pathways mediating angina pectoris. Lancet 1994;344:147-150.
44. Derbyshire SW, Jones AK. Cerebral responses to a continual tonic pain stimulus measured using positron emission tomography. Pain 1998;76: 127-135.
45. Lin Q, Peng YB, Willis WD. Role of GABA receptor subtypes in inhibition of primate spinothalamic tract neurons: difference between spinal and periaqueductal gray inhibition. J Neurophysiol 1996;75:109-123.
46. Treede RD, Meyer RA, Campbell JN. Comparison of heat and mechanical receptive fields of cutaneous C-fiber nociceptors in monkey. J Neurophysiol 1990;64:1502-1513.
47. Lynn B, Carpenter E. Primary afferent units from the hairy skin of the rat hind limb. Brain Res 1982;238:29-43.
48. Menetrey D, Chaouch A, Besson JM. Responses of spinal cord dorsal horn neurons to non-noxious cutaneous temperature changes in the spinal rat. Pain 1979;6:265-282.
49. Schmeltz M, Schmidt R, Ringkamp M, Forster C, Handwerker HO, Torebjork HE. Limitation of sensitization to injured parts of receptive fields in human skin C-nociceptors. Exp Brain Res 1996;68:1720-1732.