Differential cyclin-dependent kinase expression and activation in human colon cancer

Anticancer Research

Volumn 19, Issue 1 B, 1999, Pages 741-748

  Salh, Baljinder ^a   Bergman, David ^a   Marotta, Anthony ^a   Pelech, Steven L ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

CDK inhibitors; Colon cancer; Cyclin dependent kinases; Cyclins

Indexed keywords

CYCLIN DEPENDENT KINASE; HISTONE H1; PHOSPHOTRANSFERASE; RETINOBLASTOMA PROTEIN;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CHROMATOGRAPHY; COLON CANCER; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANTIGENS, NUCLEAR; BLOTTING, WESTERN; CDC2 PROTEIN KINASE; CDC2-CDC28 KINASES; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, ION EXCHANGE; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASES; HISTONES; HUMANS; NUCLEAR PROTEINS; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN-SERINE-THREONINE KINASES; RETINOBLASTOMA PROTEIN; TUMOR MARKERS, BIOLOGICAL;

EID: 0032945857     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Parker S, Tong T, Bolden S, Wingo, P: Cancer Statistics, 1996. CA Cancer J Clin 46: 5-27, 1996.
2. Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 61: 759-767, 1990.
3. Weinberg RA: The Retinoblastoma protein and cell cycle control. Cell 81: 323-330, 1995.
4. Arber N, Hibshoosh H, Moss SF, Sutter T, Zhang Y, Begg M, Wang S, Weinstein IB, Holt PR: Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis. Gastroenterology 110: 669-674, 1996.
5. Bartkova J, Lukas J, Strauss M, Bartek J: The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas. Int J Cancer 58: 568-573, 1994.
6. Zhang T, Nanney LB., Luongo C, Lamps L, Heppner KJ, Dubois RN, Beauchamp RD: Concurrent overexpression of cyclin D1 and cyclin-dependent kinase 4 (Cdk4) in intestinal adenomas from multiple intestinal neoplasia (Min) mice and human familial adenomatous polyposis patients. Cancer Res 57: 169-175, 1997.
7. Kitahara K, Yasui W, Kuniyasu H, Yokozaki H, Akama Y, Yunotani S, Hisatsugu T, Tahara E: Concurrent amplification of cyclin E and CDK2 genes in colorectal carcinomas. Int J Cancer 62: 25-28, 1995.
8. Musgrove EA, Lee CSL, Buckley MF, Sutherland RL: Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle. Proc Natl Acad Sci 91: 8022-8026, 1994.
9. Leach FS, Elledge SJ, Sherr CJ, Willson JKV, Markowitz S, Kinzler KW, Vogelstein B: Amplification of cyclin genes in colorectal carcinomas. Cancer Res 53: 1986-1989, 1993.
10. Jiang W, Zhang YJ, Kahn SM, Hollstein MC, Santella RM, Lu SH, Harris CC, Montesano R, Weinstein IB: Altered expressin of the cyclin D1 and retinoblastoma genes in human esophageal cancer. Proc Natl Acad Sci USA 90: 9026-9030, 1993.
11. MAPK pathway. J Biol Chem 271: 20608-20616, 1996.
12. Pines J: Cyclins and cyclin-dependent kinases: a biochemical view. Biochem J 308: 697-711, 1995.
13. Morgan DO: Principles of CDK regulation. Nature 374: 131-134, 1995.
14. White RJ: Regulation of RNA polymerases I and III by the retinoblastoma protein: a mechanism for growth control? Trends Biochem Sci 22: 77-80, 1997.
15. Taya Y: Rb kinases and Rb-Binding Proteins: New Points of View. Trends Biochem Sci 22: 14-17,1997.
16. Resnitzky D, Reed SI: Different roles for cyclins D1 and E in regulation of the G1-to-S transition. Mol Cell Biol 15: 3463-3469, 1995.
17. Yasui W, Kuniyasu H, Yokozaki H, Semba S, Shimamoto F, Tahara E: Expression of cyclin E in colorectal adenomas and adenocarcinomas: correlation with expression of Ki-67 antigen and p53 protein. Virchows Archiv 429: 13-19, 1996.
18. Levine AJ: p53, the cellular gatekeeper for growth and division. Cell 86: 323-331, 1997.
19. Hollstein M, Rice K, Greenblatt MS, Soussi T, Ruchs R, Sorlie T, Hovig E, Smith-Sorenson B, Montesano R, Harris CC: Database of p53-gene somatic mutations in human tumors and cell lines. Nucleic Acids Res 22: 3551-3555, 1994.
20. cdc2 and its kinase activity in human gastric and colonie carcinomas. Int J Cancer 53: 36-41, 1993.
21. Yamamoto H, Monden T, Ikeda K, Izawa H, Fukuda K, Fukunaga M, Tomita N, Shimano T, Shiozaki H, Monden M: Coexpression of cdk2/cdc2 and retinoblastoma gene products in colorectal cancer. Br J Cancer 71: 1231-1236, 1995.
22. Kitagawa M, Saitoh S, Ogino H, Okabe T, Matsumoto H, Okuyama A, Tamai K, Ohba Y, Yasuda H, Nishimura S et al: CDC-2-like kinase is associated with the retinoblastoma protein. Oncogene 7: 1067-1074, 1992.
23. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72: 248-254, 1976.
24. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227: 680-685, 1970.
25. Vesely J, Havlicek L, Strnad M, Blow JJ, Donella-Deana A, Pinna L, Letham DS, Kato J, Detivaud L, Leclerc S, Meier L: Inhibition of cyclin-dependent kinases by purine analogues. Eur J Biochem 224: 771-786, 1994.
26. Ball KL, Lain S, Fahraeus R, Smythe C, Lane D: Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1. Curr Biol 7: 71-80 1996
27. CDKN2/INK4A. Curr Biol 6: 84-91, 1996.
28. Lukas J, Parry D, Aagaard L, Mann DJ, Bartkova J, Strauss M, Peters G, Bartek J: Retinoblastoma-protein-dependent cell-cycle inhibition by the tumor suppressor p16. Nature 375: 503-506, 1995.
29. INK4 Science 267: 249-252, 1995.
30. Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nature Med 3: 222-225, 1997.
31. Loda M, Cukor B, Tam SW, Lavin P, Michelangelo F, Draetta G, Jessup JM, Pagano M: Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nature Med. 3: 231-234.
32. Herrera RE, Sah VP, Williams BO, Makela TP, Weinberg RA, Jacks T: Altered cell cycle kinetics, gene expression and G1 restriction point regulation in Rb-deficient fibroblasts. Mol Cell Biol 16: 2402-2407, 1996.
33. Hirai H, Sherr C: Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1. Mol Cell Biol 16: 6457-6467, 1996.
34. Wang J-K, Xu H, Li H-C, Goldfarb M: Broadly expressed SNT-like proteins link FGF receptor stimulation to activators of Ras. Oncogene 7: 721-729,1996.
35. cdc2 -associated protein kinase. Cell 57: 775-786, 1989.
36. c-crc in progressive stages of human colorectal cancer. J Clin Invest 91: 53-60, 1993.
37. Erpel T, Courtneidge SA: Src family protein tyrosine kinases and cellular signal transduction pathways. Curr Opin Cell Biol 7: 176-182, 1995.
38. Pathan AI, Geahlen RL, Harrison, ML: The protein tyrosine kinase Lck associates with and is phosphorylated by CDC2. J Biol Chem 271: 27517-27523, 1996.
39. Taylor SJ, Shalloway D: Cell cycle dependent activation of ras. Curr Biol 6: 1621-7, 1996.
40. Peeper DS, Upton TM, Ladha MH, Neuman E, Zalvide J, Bernards R, DeCaprio JA, Ewen ME: Ras signalling linked to the cell-cycle machinary by the retinoblastoma protein. Nature 386: 177-181, 1997.
41. INK4a. Cell 88: 93-602, 1997.
42. Kinzler KW, Vogelstein B: Lessons from hereditary colorectal cancer. Cell 87: 159-170, 1996.
43. Balusubramian S, Ahmad N, Jeedigunta S, Mukhtar H: Alterations in cell cycle regulation in mouse skin tumors. Biochem Biophys Res Commun 243: 744-748, 1998.