Characterization of the subtype selectivity of the allosteric modulator heptane-1,7-bis-(dimethyl-3'-phthalimidopropyl) ammonium bromide (c7/3-phth) at cloned muscarinic acetylcholine receptors

Biochemical Pharmacology

Volumn 57, Issue 2, 1999, Pages 171-179

  Christopoulos, Arthur ^a   Sorman, Jennifer L ^a   Mitchelson, Fred ^b   El Fakahany, Esam E ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Allosteric modulation; Cooperativity; Dissociation kinetics; Equilibrium binding; Muscarinic receptors

Indexed keywords

AMMONIUM DERIVATIVE; METHYLSCOPOLAMINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC M5 RECEPTOR; MUSCARINIC RECEPTOR; RECEPTOR SUBTYPE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DISSOCIATION; FEMALE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY;

EID: 0032944617     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00277-9     Document Type: Article

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