CD40 engagement modulates the production of matrix metalloproteinases by gingival fibroblasts

Clinical and Experimental Immunology

Volumn 115, Issue 1, 1999, Pages 161-167

  Wassenaar, A ^a,b   Verschoor, T ^a,b   Kievits, F ^a,b   Den Hartog, M T ^d   Kapsenberg, M L ^a   Everts, V ^a,c   Snijders, A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b Dept of Gen Pathol and Int Med ^*  (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d PanGenetics BV   (Netherlands)

Author keywords

CD40; Gingival fibroblasts; Matrix metalloproteinases; Periodontitis

Indexed keywords

CD40 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MATRIX METALLOPROTEINASE; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CASE REPORT; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FIBROBLAST; GINGIVA DISEASE; HUMAN; HUMAN CELL; PERIODONTAL DISEASE; PERIODONTITIS; PRIORITY JOURNAL; T LYMPHOCYTE;

ADULT; ANTIGENS, CD40; EXTRACELLULAR MATRIX; FIBROBLASTS; GINGIVA; HUMANS; INTERFERON TYPE II; INTERLEUKIN-1; INTERLEUKIN-6; INTERLEUKIN-8; METALLOENDOPEPTIDASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032942493     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1999.00764.x     Document Type: Article

References (37)

1. 1 Listgarten MA. Pathogenesis of periodontitis. J Clin Periodontol 1989; 13:418-30.
2. 2 Seymour GJ, Gemmell E, Reinhardt RA, Eastcott J, Taubman MA. Immunopathogenesis of chronic inflammatory disease: cellular and molecular mechanisms. J Periodont Res 1993; 28:478-86.
3. 3 Tokoro Y, Matsuki Y, Yamamoto T, Suzuki T, Hara K. Relevance of local Th2-type cytokine mRNA expression in immunocompetent infiltrates in inflamed gingival tissue to periodontal diseases. Clin Exp Immunol 1997; 107:166-74.
4. 4 Tsai CC, Ho YP, Chen CC. Levels of interleukin-1 beta and interleukin-8 in gingival crevicular fluids in adult periodontitis. J Periodont 1995; 66:852-9.
5. 5 Wassenaar A, Reinhardus C, Thepen T, Abraham-Inpijn L. Kievits F. Cloning, characterization, and antigen specificity of T-lymphocyte subsets extracted from gingival tissue of chronic adult periodontitis patients. Infect Immun 1995; 63:2147-53.
6. 6 Takahashi K, Takigawa M, Takashiba S, Nagai A, Miyamoto M, Kurihara H, Murayama Y. Role of cytokines in the induction of adhesion molecules on cultured human gingival fibroblasts. J Periodont 1994; 65:230-5.
7. 7 Wassenaar A, Snijders A, Abraham-Inpijn L. Kapsenberg ML, Kievits F. Antigen-presenting properties of gingival fibroblasts in chronic adult periodontitis. Clin Exp Immunol 1997; 110:277-84.
8. 8 Malik N, Greenfield BW, Wahl AF, Kiener PA. Activation of human monocytes through CD40 induces matrix metalloproteinases. J Immunol 1996; 156:3952-60.
9. 9 Mach F, Schonbeck U, Bonnefoy JY, Pober JS, Libby P. Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor. Circulation 1997; 96:396-9.
10. 10 Schonbeck U, Mach F, Sukhova GK, Murphy C, Bonnefoy JY, Fabunmi RP, Libby P. Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture? Circulation Res 1997; 81:448-54.
11. 11 Woessner JF. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J 1991; 5:2145-54.
12. 12 Ries C, Petrides PE. Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease. Biol Chem Hoppe-Seyler 1995; 376:345-55.
13. 13 Ingman T, Sorsa T, Michaelis J, Konttinen YT. Immunohistochemical study of neutrophil- and fibroblast-type collagenases and stromelysin-1 in adult periodontitis. Scand J Dent Res 1994; 102:342-9.
14. 14 Kubota T, Nomura T, Takahashi T, Hara K. Expression of mRNA for matrix metalloproteinases and tissue inhibitors of metalloproteinases in periodontitis-affected human gingival tissue. Arch Oral Biol 1996; 41:253-62.
15. 15 Birkedal-Hansen H. Role of cytokines and inflammatory mediators in tissue destruction. J Periodont Res 1993; 28:500-10.
16. 16 De Boer M, Conroy L, Min HY, Kwekkeboom J. Generation of monoclonal antibodies to human lymphocyte cell surface antigens using insect cells expressing recombinant proteins. J Immunol Methods 1992; 152:15-23.
17. 17 Fries KM, Sempowski CD, Gaspari AA, Blieden T, Looney RJ, Phipps RP. CD40 expression by human fibroblasts. Clin Immunol Immunopathol 1995; 77:42-51.
18. 18 Sempowski GD, Chess PR, Moretti AJ, Padilla J, Phipps RP, Blieden TM. CD40 mediated activation of gingival and periodontal ligament fibroblasts. J Periodont 1997; 68:284-92.
19. 19 Dongari-Bagtzoglou AI, Warren WD, Berton MT, Ebersole JL. CD40 expression by gingival fibroblasts: correlation of phenotype with function. Int Immunol 1997; 9:1233-41.
20. 20 Sakurada S, Kato T, Okamoto T. Induction of cytokines and ICAM-1 by proinflammatory cytokines in primary rheumatoid synovial fibroblasts and inhibition by N-acetyl-L-cysteine and aspirin. Int Immunol 1996; 8:1483-93.
21. 21 Circolo A, Welgus HG, Pierce GF, Kramer J, Strunk RC. Differential regulation of the expression of proteinases/antiproteinases in fibroblasts: effects of interleukin-1 and platelet-derived growth factor. J Biol Chem 1991; 266:12283-8.
22. 22 Rutter JL, Benbow U, Coon CI, Brinckerhoff CE. Cell-type specific regulation of human interstitial collagenase-1 gene expression by interleukin-1 beta (IL-beta) in human fibroblasts and BC-8701 breast cancer cells. J Cell Biochem 1997; 66:322-36.
23. 23 Unemori EN, Bair MJ, Bauer EA, Amento EP. Stromelysin expression regulates collagenase activation in human fibroblasts. Dissociable control of two metalloproteinases by interferon. J Biol Chem 1991; 266:23477-82.
24. 24 Varga J, Yufit T, Brown RR. Inhibition of collagenase and stromelysin gene expression by interferon-gamma in human dermal fibroblasts is mediated in part via induction of tryptophan degradation. J Clin Invest 1995; 96:475-81.
25. 25 Okada Y, Morodomi T, Enghild JJ, Suzuki K, Yasui A, Nakanishi I, Salvesen G, Nagase H. Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts. Purification and activation of the precursor and enzymic properties. Eur J Biochem 1990; 194:721-30.
26. 26 Miltenburg AMM, Lacraz S, Welgus HG, Dayer J. Immobilized anti-CD3 antibody activates T cell clones to induce the proliferation of interstitial collagenase, but not tissue inhibitor of metalloproteinases, in monocytic THP-1 cells and dermal fibroblasts. J Immunol 1995; 154:2655-67.
27. 27 Yellin MJ, Winikoff S, Fortune SM, Baum D, Crow MK, Lederman S, Chess L. Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD106 (VCAM-1) up-regulation and IL-6 production and proliferation. J Leuc Biol 1995; 58:209-16.
28. 28 Rissoan MC, van Kooten C, Chomarat P, Galibert L, Durand I, Thivolet-Bejui F, Miossec P, Banchereau J. The functional CD40 antigen of fibroblasts may contribute to the proliferation of rheumatoid synovium. Clin Exp Immunol 1996; 106:481-90.
29. 29 Richards CD, Shoyab M, Brown TJ, Gauldi J. Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture. J Immunol 1993; 150:5596-603.
30. 30 Shingu M, Nagai Y, Isayama T, Naono T, Nobunaga M, Nagai Y. The effects of cytokines on metalloproteinase inhibitors (TIMP) and collagenase production by human chondrocytes and TIMP production by synovial cells and endothelial cells. Clin Exp Immunol 1993; 94:145-9.
31. 31 Baragi VM, Brott DA, Qiu L, Conroy MC, Lalwani ND. Immunofluorescence quantitation of stromelysin in human synovial fibroblasts by confocal laser scanning microscopy. Lab Invest 1995; 72:484-90.
32. 32 MacNaul KL, Chartrain N, Lark M, Tocci MJ, Hutchinson NI. Dis-coordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinase-1 in rheumatoid human synovial fibroblasts. Synergistic effects of interleukin-1 and tumor necrosis factor alpha on stromelysin expression. J Biol Chem 1990; 265:17238-45.
33. 33 van Kooten C, Banchereau J. Functions of CD40 on B cells, dendritic cells and other cells. Cur Opin Immunol 1997; 9:330-7.
34. 34 Peguet-Navarro J, Dalbiez-Gauthier C, Moulon C et al. CD40 ligation of human keratinocytes inhibits their proliferation and induces their differentiation. J Immunol 1997; 158:144-52.
35. 35 Schonbeck U, Mach F, Bonnefoy JY, Loppnow H, Flad HD, Libby P. Ligation of CD40 activates interleukin 1beta-converting enzyme (caspase-1) in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1 beta. J Biol Chem 1997; 272:19569-74.
36. 36 Tanaka H, Sukhova G, Schwartz D, Libby P. Proliferating arterial smooth muscle cells after balloon injury express TNF-alpha but not interleukin-1 or basic fibroblast growth factor. Arteriosel Thromb Vasc Biol 1996; 16:12-18.
37. + T-cell subsets isolated from chronic adult periodontitis tissue differ in surface phenotype and biological functions. Immunology 1996; 87:113-8.