Tat activates human immunodeficiency virus type 1 transcriptional elongation independent of TFIIH kinase

Molecular and Cellular Biology

Volumn 19, Issue 4, 1999, Pages 2863-2871

  Chen, Dan ^a   Zhou, Qiang ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR; CYCLIN DEPENDENT KINASE; ELONGATION FACTOR; RNA POLYMERASE II; TRANSACTIVATOR PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

GALLUS GALLUS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0032935399     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.4.2863     Document Type: Article

References (45)

1. Adamczewski, J. P., M. Rossignol, J. P. Tassan, E. A. Nigg, V. Moncollin, and J. M. Egly. 1996. MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH. EMBO J. 15:1877-1884.
2. Akoulitchev, S., T. P. Makela, R. A. Weinberg, and D. Reinberg. 1995. Requirement for TFIIH kinase activity in transcription by RNA polymerase II. Nature 377:557-560.
3. Blau, J., H. Xiao, S. McCracken, P. O'Hare, J. Greenblatt, and D. Bentley. 1996. Three functional classes of transcriptional activation domain. Mol. Cell. Biol. 16:2044-2055.
4. Chen, D., Y. Fong, and Q. Zhou. Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription. Proc. Natl. Acad. Sci. USA, in press.
5. Chun, R. F., and K. T. Jeang. 1996. Requirements for RNA polymerase II carboxyl-terminal domain for activated transcription of human retroviruses human T-cell lymphotropic virus I and HIV-1. J. Biol. Chem. 271:27888-27894.
6. Cujec, T. P., H. Okamoto, K. Fujinasa, J. Meyer, H. Chamberlin, D. O. Morgan, and B. M. Peterlin. 1997. The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II. Genes Dev. 11:2645-2657.
7. Dahmus, M. E. 1996. Reversible phosphorylation of the C-terminal domain of RNA polymerase II. J. Biol. Chem. 271:19009-19012.
8. Fisher, R. P., P. Jin, H. M. Chamberlin, and D. O. Morgan. 1995. Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase. Cell 83:47-57.
9. Garcia-Martinez, L. F., G. Mavankal, J. M. Neveu, W. S. Lane, D. Ivanov, and R. B. Gaynor. 1997. Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription. EMBO J. 16:28.36-2850.
10. Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, N.Y.
11. Herrmann, C. H., and A. P. Rice. 1995. Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperpliosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor. J. Virol. 69:1612-1620.
12. Jones, K. A. 1997. Taking a new TAK on Tat transactivation. Genes Dev. 11: 2593-2599.
13. Jones, K. A., and B. M. Peturlin. 1994. Control of RNA initiation and elongation at the HIV-1 promoter. Annu. Rev. Biochem. 63:717-743.
14. Kephart, D. D., N. F. Marshall, and D. H. Price. 1992. Stability of Drosophila RNA polymerase II elongation complexes in vitro. Mol. Cell. Biol. 12:2067-2077.
15. Lee, D., and J. T. Lis. 1998. Transcriptional activation independent of TKIIH kinase and the RNA polymerase II mediator in vivo. Nature 393:389-392.
16. Li, X., and M. R. Green. 1998 The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor. Genes Dev. 12:2992-2996.
17. Liao, S. M., J. Zhang, D. A. Jeffery, A. J. Koleske, C. M. Thompson, D. M. Chao, M. Viljoen, H. J. van Vuuren, and R. A. Young. 1995. A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature 374:193-196.
18. Lu, X., T. M. Welsh, and B. M. Peterlin. 1993. The human immunodeficiency virus type 1 long terminal repeat specifies two different transcription complexes, only one of which is regulated by Tat. J. Virol. 67:1752-1760.
19. Makela, T. P., J. D. Parvin, J. Kim, L. J. Huber, P. A. Sharp, and R. A. Weinberg. 1995. A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription. Proc. Natl. Acad. Sci. USA 92:5174-5178.
20. Maldonado, E., and D. Reinberg, 1995. News on initiation and elongation of transcription by RNA polymerase II. Curr. Opin. Cell Biol. 7:352-361.
21. Mancebo, H. S., G. Lee, J. Flygare, J. Tomassini, P. Luu, Y. Zhu, J. Peng, C. Blau, D. Hazuda, D. Price, and O. Flores. 1997. P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro. Genes Dev. II: 2633-2644.
22. Marciniak, R. A., and P. A. Sharp. 1991. HIV-1 Tat protein promotes formation of more-proeessive elongation complexes. EMBO J. 10:4189-4196.
23. Marshall, N. F., J. Peng, Z. Xie, and D. H. Price. 1996. Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase. J. Biol. Chem. 271:27176-27183.
24. Marshall, N. F., and D. H. Price. 1995. Purification of P-TEFb, a transcription factor required for the transition into productive elongation. J Biol. Chem. 270:12335-12338.
25. McNeil, J., H. Agah, and D. Bentley. 1998. Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast. Genes Dev. 12:2510-2521.
26. Okamoto, H., C. T. Sheline, J. L. Corden, K. A. Jones, and B. M. Peterlin. 1996. Trans-activation by human immunodeficiency virus Tat protein requires the C-terminal domain of RNA polymerase II. Proc. Natl. Acad. Sci. USA 93:11575-11579.
27. O'Keeffe, B., Y. Fong, D. Chen, and Q. Zhou. Requirement for a kinase-specific chaperone pathway in the produclion of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated Tat stimulation of HIV-1 transcription, Submitted for publication.
28. Parada, C. A., and R. G. Roeder. 1996. Enhanced processivity of RNA polymorase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain. Nature 384:375-378.
29. Parvin, J. D., and P. A. Sharp. 1993. DNA topology and a minimal set of basal factors for transcription hy RNA polymenise II. Cell 73:533-540.
30. Parvin, J. D., B. M. Shykind, R. E. Meyers, J. Kim, and P. A. Sharp. 1994. Multiple sels of basal factors initiate transcription by RNA polymerase II. J. Biol. Chem. 269:18414-18421.
31. Parvin, J. D., H. T. Timmers, and P. A. Sharp. 1992. Promoter specificity of basal transcription factors. Cell 68:1135-1144.
32. Peng, J., Y. Zhu, J. T. Milton, and D. H. Price. 1998. Identification of multiple cyclin subunits of human P-TEFb. Genes Dev. 12:755-762.
33. Rice, A. P., and F. Carlotti. 1990. Structiral analysis of wild-type and mutant human immunodeficieny virus type I Tat proteins. J. Virol. 64:6018-6026.
34. Roy, R., J. P. Adamezewski, T. Seroz, W. Vermeulen, J. P. Tassan, L. Schaeffer, E. A. Nigg, J. H. Hoeijmakers, and J. M. Egly. 1994. The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor. Cell 79: 1093-1101.
35. Serizawa, H., T. P. Makela, J. W. Conaway, R. C. Conaway, R. A. Weinberg, and R. A. Young. 1995. Association of Cdk-activating kinase subunits with transcription factor TFIIH. Nature 374:280-282.
36. Shiekhattar, R., F. Mermelstein, R. P. Fisher, R. Drapkin, B. Dynlacht, H. C. Wessling, D. O. Morgan, and D. Reinberg. 1995. Cdk-activating kinase complex is a component of human transcription factor TFIIH. Nature 374: 283-287.
37. Svejstrup, J. Q., P. Vichi, and J. M. Egly, 1996. The multiple roles of transcription/repair factor TFIIH. Trends Biochem. Sci. 21:346-350.
38. Wei, P., M. E. Garber, S. M. Fang, W. H. Fischer, and K. A. Jones. 1998. A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell 92:451-462.
39. Yang, X., C. H. Herrmann, and A. P. Rice. 1996 The human immunodeficiency virus Tat proteins specifically associate with TAK in vivo and require the carboxyl-terminal domain of RNA polymerase II for function, J. Virol. 70:4570-4584
40. Yankulov, K., and D. Bentley. 1998. Transcriptional control: Tat cofactors and transcriptional elongation. Curr. Biol. 8:447-449.
41. Zawel, L., K. P. Kumar, and D. Reinberg. 1995. Recycling of the general transcription factors during RNA polymerasc II transcription. Genes Dev. 9: 1479-1490.
42. Zhou, Q., D. Chen, E. Pierstorff, and K. Luo. 1998. Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages. EMBO J. 17:3681-3691.
43. Zhou, Q., P. M. Lieberman, T. G. Boyer, and A. J. Berk. 1992. Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter. Genes Dev. 6:1964-1974.
44. Zhou, Q., and P. A. Sharp. 1995. Novel mechanism and factor for regulation bv HIV-1 Tat. EMBO J. 14:321-328.
45. Zhu, Y., T. Pe'ery, J. Peng, V. Ramnathan, N. Marshall, T. Marshall, B. Amendt, M. B. Mathews, and D. H. Price. 1997 Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro. Genes Dev.