Differential effects of cis and trans fatty acids on insulin release from isolated mouse islets

Metabolism: Clinical and Experimental

Volumn 48, Issue 1, 1999, Pages 22-29

  Alstrup, Kirsten Kudahl ^a   Gregersen, Søren ^a   Jensen, Heidi Majgaard ^a   Thomsen, Janus Laust ^a   Hermansen, Kjeld ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ELAIDIC ACID; INSULIN; LEUCINE; OLEIC ACID;

ANIMAL EXPERIMENT; ARTICLE; DISEASE ASSOCIATION; FEMALE; GLUCOSE OXIDATION; HORMONAL REGULATION; HYPERLIPIDEMIA; INSULIN LIKE ACTIVITY; INSULIN RELEASE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

EID: 0032934256     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(99)90005-7     Document Type: Article

References (48)

1. Chen YDI, Golay A, Swislocki ALM, et al: Resistance to insulin suppression of plasma free fatty acid concentrations and insulin stimulation of glucose uptake in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 64:17-21, 1987
2. Gordon ES: Non-esterified fatty acids in the blood of obese and lean subjects. Am J Clin Nutr 8:740-747, 1960
3. Lee Y, Hirose H, Ohneda M, et al: Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-beta-cell relationships. Proc Natl Acad Sci USA 91:10878-10882, 1994
4. Zhou YP, Grill V: Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest 93:870-876, 1994
5. Milburn JL, Hirose H, Lee Y, et al: Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. J Biol Chem 270:1295-1299, 1995
6. Elks ML: Chronic perifusion of rat islets with palmitate suppresses glucose-stimulated insulin release. J Endocrinol 133:208-214, 1993
7. Opara EC, Garfinkel M, Hubbard VS, et al: Effect of fatty acids on insulin release: Role of chain length and degree of unsaturation. Am J Physiol 266:E635-E639, 1994
8. Zhou YP, Ling Z, Grill V: Inhibitory effects of fatty acids on glucose-regulated β-cell function: Association with increased islet triglyceride stores and altered effect of fatty acid oxidation on glucose metabolism. Metabolism 45:981-986, 1996
9. Warnotte C, Gilon P, Nenquin M, et al: Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells. Diabetes 43:703-711, 1994
10. Conget I, Rasschaert J, Sener A, et al: Secretory, biosynthetic, respiratory, cationic, and metabolic responses of pancreatic islets to palmitate and oleate. Biochem Med Metab Biol 51:175-184, 1994
11. Balasse EO, Ooms HA: Role of plasma free fatty acids in the control of insulin secretion in man. Diabetologia 9:145-151, 1973
12. Zhou YP, Berggren P, Grill V: A fatty acid-induced decrease in pyruvate dehydrogenase activity is an important determinant of beta-cell dysfunction in the obese diabetic db/db mouse. Diabetes 45:580-586, 1996
13. Garfinkel M, Lee S, Opara EC, et al: Insulinotropic potency of lauric acid: A metabolic rationale for medium chain fatty acids (MCF) in TPN formulation. J Surg Res 52:328-333, 1992
14. Prentki M, Vischer S, Glennon MC, et al: Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion. J Biol Chem 267:5802-5810, 1992
15. Stein DT, Stevenson BE, Chester MW, et al: The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation. J Clin Invest 100:398-403, 1997
16. Christiansen E, Schneider S, Palmvig B, et al: Intake of a diet high in trans monounsaturated fatty acids or saturated fatty acids. Diabetes Care 20:881-887, 1997
17. Emken EA: Nutrition and biochemistry of trans and positional fatty acid isomers in hydrogenated oils. Annu Rev Nutr 4:339-376, 1984
18. Becker W: Intake of trans fatty acids in the Nordic countries. Scand J Nutr/Naringsforskning 40:16-18, 1996
19. Lacy PE, Kostianovsky M: Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16:35-39, 1967
20. Gregersen S, Thomsen JL, Brock B, et al: Endothelin-1 stimulates insulin secretion by direct action on the islets of Langerhans in mice. Diabetologia 39:1030-1035, 1996
21. Pedersen O, Hjcllund E, Lindskov HO: Insulin binding and action on fat cells from young healthy females and males. Am J Physiol 243:E158-E167, 1982
22. Randle PJ, Garland PB, Hales CN, et al: The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbance of diabetes mellitus. Lancet 1:785-789, 1963
23. Weber G, Convery HJH, Lea MA, et al: Feedback inhibition of key glycolytic enzymes in liver: Action of free fatty acids. Science 154:1357-1360, 1966
24. Randle PJ, Priestman DA, Mistry SC, et al: Glucose fatty acid interactions and the regulation of glucose disposal. J Cell Biochem 55S:1-11, 1994(suppl)
25. Alcazar O, Qiu-yue Z, Giné E, et al: Stimulation of islet protein kinase C translocation by palmitate requires metabolism of the fatty acid. Diabetes 46:1153-1158, 1997
26. 14C-labeled delta 9,12-octadecadienoic acid by the fasting rat. Biochim Biophys Acta 144:525-531, 1967
27. Lanser AC, Emken EA, Ohlrogge JB: Oxidation of oleic and elaidic acids in rat and human heart homogenates. Biochim Biophys Acta 875:510-515, 1986
28. Lawson LD, Kummerow FA: Beta-oxidation of the coenzyme A esters of vaccenic, elaidic and petroselaidic acids by rat heart mitochondria. Lipids 14:501-503, 1978
29. Lawson LD, Kummerow FA: Beta-oxidation of the coenzyme A esters of elaidic, oleic and stearic acids and their full-cycle intermediates by rat heart mitochondria. Biochim Biophys Acta 573:245-254, 1979
30. Lawson LD, Holman RT: Beta-oxidation of the geometric and positional isomers of octadecenoic acid by rat heart and liver mitochondria. Biochim Biophys Acta 665:60-65, 1981
31. Malaisse WJ, Malaisse-Lagae F, Sener A, et al: Participation of endogenous fatty acids in the secretory activity of the pancreatic B-cell. Biochem J 227:995-1002, 1985
32. Prentki M: New insights into pancreatic beta-cell metabolic signaling in insulin secretion. Eur J Endocrinol 143:272-286, 1996
33. Malaisse WJ, Sener A, Herchuelz A, et al: Insulin release: The fuel hypothesis. Metabolism 28:373-386, 1979
34. 2+ mobilization and protein kinase C. Diabetes 37:1453-1469, 1998
35. 2+ handling by permeabilized clonal pancreatic beta-cells. J Biol Chem 267:19840-19845, 1992
36. + channels in insulinoma cells are activated by nonesterified fatty acids. Biochemistry 31:4656-4661, 1992
37. Henquin JC, Meissner HP: Effects of amino acids on membrane potential and 86Rb+ fluxes in pancreatic beta-cells. Am J Physiol 240:E245-E252, 1981
38. Flatt PR, Barnett CR, Shibier O, et al: Direct and indirect actions of nutrients in the regulation of insulin secretion from the pancreatic beta-cells. Proc Nutr Soc 50:559-566, 1991
39. Zawalich WS: Time-dependent potentiation of insulin release induced by alpha-ketoisocaproate and leucine in rats: Possible involvement of phosphoinositide hydrolysis. Diabetologia 31:435-442, 1988
40. Best L, Malaisse WJ: Phospholipids and islet function. Diabetologia 25:299-305, 1983
41. Vorum H, Brodersen R: Adsorption and physical state of medium- and long-chain fatty acids in neutral aqueous buffer solution. Chem Phys Lipids 74:43-48, 1994
42. Brodersen R, Vorum H, Skriver E, et al: Serum albumin binding of palmitate and stearate. Multiple binding theory for insoluble ligands. Eur J Biochem 182:19-25, 1989
43. Cistola DP, Hamilton JA, Jackson D, et al: Ionization and phase behavior of fatty acids in water: Application of the Gibbs phase rule. Biochemistry 27:1881-1888, 1988
44. Corr PB, Gross RW, Sobel BE: Amphipathic metabolites and membrane dysfunction in ischemic myocardium. Circ Res 55:135-154, 1984
45. Pande SV, Mead JF: Inhibition of enzyme activities by free fatty acids. J Biol Chem 243:6180-6185, 1968
46. Spector AA, Fletcher JE, Ashbrook JD: Analysis of long-chain free fatty acid binding to bovine serum albumin by determination of stepwise equilibrium constants. Biochemistry 10:3229-3232, 1971
47. Nestel P, Noakes M, Belling B, et al: Plasma lipoprotein lipid and Lp(a) changes with substitution of elaidic acid or oleic acid in the diet. J Lipid Res 33:1029-1036, 1992
48. Siguel EN, Lerman RH: Trans-fatty acid patterns in patients with angiographically documented coronary artery disease. Am J Cardiol 71:916-920, 1993