Investigation of the expression of IL-1β converting enzyme and apoptosis in normal and inflammatory bowel disease (IBD) mucosal macrophages

Clinical and Experimental Immunology

Volumn 116, Issue 2, 1999, Pages 251-257

  McAlindon, M E ^b   Galvin, A ^a   McKaig, B ^b   Gray, T ^a   Sewell, H F ^a   Mahida, Y R ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

^b NONE

Author keywords

Apoptosis; Crohn's disease; Macrophages; Ulcerative colitis

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; INTERLEUKIN 1;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL VIABILITY; CLINICAL ARTICLE; COLON MUCOSA; CONTROLLED STUDY; ENTERITIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LAMINA PROPRIA; MACROPHAGE; MACROPHAGE ACTIVATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIGENS, CD14; APOPTOSIS; CASPASE 1; COLON; HUMANS; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; MACROPHAGES;

EID: 0032923019     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1999.00884.x     Document Type: Article

References (45)

1. 1 Selby WS, Poulter LW, Hobbs S, Jewell DP, Janossy G. Heterogeneity of HLA-DR-positive histiocytes in human intestinal lamina propria: a combined histochemical and immunohistological analysis. J Clin Pathol 1983; 36:379-84.
2. 2 Mahida YR, Patel S, Gionchetti P, Vaux D, Jewell DP. Macrophage subpopulations in lamina propria of normal and inflamed colon and terminal ileum. Gut 1989; 30:826-34.
3. 3 Allison MC, Cornwall S, Poulter LW, Dhillon AP. Macrophage heterogeneny in normal colonic mucosa and in inflammatory bowel disease. Gut 1988; 29:1531-8.
4. 4 Mahida YR, Patel S, Wu K, Jewell DP. Interleukin 2 receptor expression by macrophages in inflammatory bowel disease. Clin Exp Immunol 1988; 74:382-6.
5. 5 Neurath MF, Pettersson S, Meyer Zum Büsehenfelde K-H, Strober W. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-ΚB abrogates established experimental colitis in mice. Nature Med 1996; 2:998-1004.
6. 6 Mahida YR, Wu KC, Jewell DP. Respiratory burst activity of intestinal macrophages in normal and inflammatory bowel disease. Gut 1989; 30:1362-70.
7. 7 Rugtveit J, Haraldsen G, Høgåsen AK, Bakka A, Brandtzaeg P, Scott H. Respiratory burst of intestinal macrophages in inflammatory bowel disease is mainly caused by CD14+L1+ monocyte derived cells. Gut 1995; 37:367-73.
8. 8 Cappello M, Keshav A, Prince C, Jewell DP, Gordon S. Detection of mRNAs for macrophage products in inflammatory bowel disease by in situ hybridisation. Gut 1992; 33:1214-9.
9. 9 Mahida YR, Wu KC, Jewell DP. Characterisation of antigen-presenting capacity ot intestinal mononuclear cells isolated from normal and inflammatory bowel disease colon and ileum. Immunol 1988; 65:543-9.
10. 10 Mahida YR, Wu K, Jewell DP. Enhanced production of interleukin-1β by mononuclear cells isolated from mucosa with active ulcerative colitis or Crohn's disease. Gut 1989; 30:835-8.
11. 11 Youngman KR, Simon PL., West GA et al. Localisation of intestinal interleukin 1 activity and protein and gene expression to lamina propria cells, Gastroenterol 1993; 104:749-58.
12. 12 McAlindon ME, Hawkey CJ, Mahida YR. The expression of interleukin-1β and interleukin-1β converting enzyme in health and inflammatory bowel disease. Gut 1998; 42:214-9.
13. 13 Cerretti DP, Koslosky CJ, Mosley B et al. Molecular cloning of the interleukin-1β converting enzyme. Science 1992; 256:97-100.
14. 14 Thornberry NA, Bull HG, Calaycay JR et al. A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature 1992; 356:708-74.
15. 15 Wilson KP, Black J-AF, Thomson JA et al. Structure and mechanism of interleukin-1β converting enzyme. Nature 1994; 370:270-5.
16. 16 Hogquist KA, Nell MA, Unanue ER, Chaplin DD. Interleukin 1 is processed and released during apoptosis. Proc Natl Acad Sci USA 1991; 88:8485-9.
17. 17 Miura M, Zhu H, Rotello R, Hartwieg EA, Yuan J. Induction of apoptosis in fibroblasts by IL-1β converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 1993; 75:653-60.
18. 18 Meuret G, Bitzi A, Hammer B. Macrophage turnover in Crohn's disease and ulcerative colitis, Gastroenterol 1978; 74:501-3.
19. 19 Grimm MC, Pullman WE, Bennett GM, Sullivan PJ, Pavli P, Doe WF. Direct evidence of monocyte recruitment to inflammatory bowel disease mucosa. J Gastroenterol Hepatol 1995; 10:387-95.
20. 20 Mahida YR, Galvin AM, Gray T, Makh S, McAlindon ME, Sewell HF, Podolsky DK. Migration of human intestinal lamina propria lymphocytes, macrophages and eosinophils following the loss of surface epithelial cells. Clin Exp Immunol 1997; 109:377-86.
21. 21 McAlindon MH, Gray T, Galvin A, Sewell HF, Podolsky DK, Mahida YR. Differential lamina propria cell migration via basement membrane pores of inflammatory bowel disease mucosa. Gastroenterol 1998; 115:841-8.
22. 22 Robinson G, Gray T. Electron microscopy 2. Tissue preparation, sectioning and staining. In: Bancroft JD, Stevens A, eds. Theory and practice of histological techniques, 3rd edn. London: Churchill Livingstone, 1990:525-62.
23. 23 Arends MJ, Morris RG, Wyllie AH. Apoptosis: the role of the endonuclease. Am J Pathol 1990; 136:593-608.
24. 24 Nieoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991; 139:271-9.
25. 25 Mahida YR, Galvin A, Makh S, Hyde S, Santillipo L, Borriello SP, Sewell HF. Effect of Clostridium difficile toxin A on human colonic lamina propria cells: early loss of macrophages followed by T cell apoptosis. Infect Immun 1998; 66:5462-9.
26. 26 Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis. How cytometric detection of phosphatidylserine expression on early apoptolic cells using fluorescein labelled Annexin V. J Immunol Methods 1995; 184:39-51.
27. 27 Zhang C, Ao Z, Seth A, Schlossman SF. A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptolic cells. J Immunol 1996; 157:3980-7.
28. 28 Davey FR, Erber WN, Pulford KAF, Gatter KC, Mason DY. Monoclonal antibody Y1/82A with specificity towards peripheral blood monocytes and tissue macrophages. J Clin Pathol 1988; 41:753-8.
29. 29 Rugtveit J, Brandtzaeg P, Halstensen TS, Fausa O, Scott H. Increased macrophage subset in inflammatory bowel disease: apparent recruitment from peripheral blood monocytes. Gut 1994; 35:669-74.
30. 30 Grimm MC, Pavli P, Van De Pol E, Doe WF. Evidence for a CD14+ populalion of monocytes in inflammatory bowel disease mucosa-implications for pathogenesis. Clin Exp Immunol 1995; 100:291-7.
31. 31 Dinarello CA. The interleukin-1 family: 10 years of discovery. FASEB J 1994; 8:1314-25.
32. 32 Hogquist KA, Unanue ER, Chaplin DD. Release of IL-1 from mononuclear phagocytes. J Immunol 1991; 147:2181-6.
33. 33 Zychlinsky A, Fitting C, Cavaillon J-M, Sansonetti PJ. Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella fexneri. J Clin Invest 1994; 94:1328-32.
34. 34 Molloy A, Laochumroonvorapong P, Kaplan G, Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guérin. J Exp Med 1994; 180:1499-509.
35. 35 Friedlander RM, Gagliardini V, Hara H, MacDonald G, Greenberg AH, Moskowitz MA, Yuan J. Inhibition of neuronal apoptosis in a transgenic mouse expressing a dominant negative mutant of ICE. J Exp Med 1997; 185:933-40.
36. 36 Friedlander RM, Gagliardini V, Wang J, Brown RH, Yuan J. Protection in an ALS model by a dominant negative ICE inhibitor. Nature 1997; 388:31.
37. 37 Friedlander RM, Gagliardini V, Rotello RJ, Yuan J. Functional role of interleukin-1β (IL-1β) in IL-1β-converting enzyme-mediated apoptosis. J Exp Med 1998; 184:717-24.
38. 38 Li P, Allen H, Banerjee S et al. Mice deficient in IL-1β converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. Cell 1995; 80:401-11.
39. 39 Nieholson DW, Ali A, Thomberry NA et al. Indentification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995; 376:37-43.
40. 40 Carson DA, Ribeiro JM. Apoptosis and disease. Lancet 1993; 341:1251-4.
41. 41 Savill J, Wylie AH, Henson JE, Walport MJ, Henson PM, Haslett C. Macrophage apoptosis of aging neutrophils in inflammation. J Clin Invest 1989; 83:865-75.
42. 42 Bellingan GJ, Caldwell H, Howie SEM, Dransfield I, Haslett C. In vivo fate of the inflammatory macrophage during the resolution of inflammation. J Immunol 1996; 157:2577-85.
43. 43 Schreiber S, Heinig T, Panzer U, Reinking R, Bouchard A, Stahl PD, Raedler A. Impaired response of activated mononuclcar phagocytes to interleukin 4 in inflammatory bowel disease. Gastroenterology 1995; 108:21-33.
44. 44 Mahida YR. Intestinal macrophages in inflammatory bowel disease. In: Andus T, Goebell H, Layer P, Schölmerich J, eds. Inflammatory bowel diseases - from bench to bedside. London: Kluwer Acedemic Publishers, 1997:93-96.
45. 45 Podolsky DK, Lobb R, King N et al. Attenuation of colitis in the cotton-top tamarin by anti-α4 integrin monoclonal antibody. J Clin Invest 1993; 92:372-80.