Increased mature and immature CCR3 messenger RNA+ eosinophils in bone marrow from patients with atopic asthma compared with atopic and nonatopic control subjects

Journal of Allergy and Clinical Immunology

Volumn 103, Issue 1 I, 1999, Pages 99-106

  Zeibecoglou, Kyriaki ^a   Sun, Ying ^a   Yamada, Takashi ^a   North, Janet ^a   Burman, John ^b   Bungre, Jatinder ^a   Meng, Qiu ^a   Kay, A Barry ^a   Robinson, Douglas S ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^b ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

Asthma; Atopy; Bone marrow; Eosinophil; Progenitor cell

Indexed keywords

ADULT; ALLERGIC ASTHMA; ARTICLE; BONE MARROW CELL; BRONCHUS MUCOSA; CELL INFILTRATION; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; EOSINOPHIL; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL;

EID: 0032922642     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(99)70532-4     Document Type: Article

References (36)

1. Busse WW, Calhoun WF, Sedgwick JD. Mechanism of airway inflammation in asthma. Am Rev Respir Dis 1993;147:S20-4.
2. Greaves MF, Brown J, Molgaard HV, et al. Molecular features of CD34: a hemopoietic progenitor cell-associated molecule. Leukemia 1992;6(suppl):31-6.
3. + cells that lack detectable T cell, B cell, and myeloid cell antigens produce multiple colony-forming cells when cultured with marrow stromal cells. J Exp Med 1990;172:355-8.
4. + marrow cells in patients with breast cancer or neuroblastema. Blood 1991;77:1717-22.
5. + cells: messenger RNA analysis. J Allergy Clin Immunol 1996; 98:344-54.
6. + cells from asthmatic subjects. J Clin Invest 1997;100:2466-75.
7. + hemopoietic progenitor cells in atopic subjects. Am J Respir Cell Mol Biol 1996;15:645-55.
8. Gibson PG, Dolovich G, Girgis-Gabardo A, et al. The inflammatory response in asthma exacerbation: changes in circulating eosinophils, basophils and their progenitors. Clin Exp Allergy 1990;20:661-8.
9. Woolley M, Denburg J, Ellis R, Dahlback M, O'Byrne P. Allergen-induced changes in bone marrow progenitors and airway responsiveness in dogs and the effect of inhaled budesonide on those parameters. Am J Respir Cell Mol Biol 1994;11:600-6.
10. Gaspar-Elsas MI, Joseph D, Elsas PX, Vargaftig BB. Rapid increase in bone marrow eosinophil production and responses to eosinopoietic interleukins triggered by intranasal allergen challenge. Am J Respir Cell Mol Biol 1997;17:404-13.
11. Jose PJ, Griffiths Johnson DA, et al. Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. J Exp Med 1994;179:881-7.
12. Ponath PD, Qin S, Post TW, et al. Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J Exp Med 1996;183:2437-48.
13. Heath H, Qin S, Rao P, et al. Chemokine receptor usage by human eosinophils: the importance of CCR3 demonstrated using an antagonistic monoclonal antibody. J Clin Invest 1997;99:178-84.
14. Daugherty BL, Siciliano SJ, DeMartino JA, Malkowitz L, Sirotina A, Springer MS. Cloning, expression, and characterization of the human eosinophil eotaxin receptor. J Exp Med 1996;183:2349-54.
15. Collins PD, Marleau S, Griffiths Johnson DA, Jose PJ, Williams TJ. Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. J Exp Med 1995;182:1169-74.
16. Mould AW, Matthaei KI, Young IG, Foster PS. Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice. J Clin Invest 1997;99:1064-71.
17. Cockcroft DW, Killian DN, Mellon JJ, Hargreave FE. Bronchial reactivity to inhaled histamine: a method and clinical survey. Clin Allergy 1977; 7:235-43.
18. Goldman JM. Granulocytes, monocytes and their benign disorders. In: Lewis SM, Hoffbrand AV, editors. Postgraduate hematology. Oxford: Butterworth-Heinemann; 1989. p. 234-9.
19. Denburg JA, Telizyn S, Messner H, et al. Heterogeneity of human peripheral blood eosinophil-type colonies: evidence for a common basophil-eosinophil progenitor. Blood 1985;66:312-8.
20. Sutherland DR, Anderson L, Keeney M, Nayar R, Chin-Yee I. The ISHAGE guidelines for CD34+ cell determination by flow cytometry. J Hematother 1996;5:213-26.
21. Gratama J, Kraan J, Levering W, Van Bockstaele D, Rijkers G, Van der Schoot E. Analysis of variation in results of CD34+ hematopoietic progenitor cell enumeration in a multicenter study. Cytometry 1997;30:109-17.
22. Ying S, Durham SR, Corrigan CJ, Hamid Q, Kay AB. Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects. Am J Respir Cell Mol Biol 1995;12:477-87.
23. Garcia Zepeda EA, Rothenberg ME, Ownbey RT, Celestin J, Leder P, Luster AD. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat Med 1996;2:449-56.
24. Hamid Q, Azzawi M, Ying S, et al. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin Invest 1991;87:1541-6.
25. Ying S, Robinson DS, Meng Q, et al. Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma: association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells. Eur J Immunol 1997;27:3507-16.
26. Palframan RT, Collins PD, Williams TJ, Rankin SM. Eotaxin induces a rapid release of eosinophils and their precursors from the bone marrow. Blood 1998;91:2240-8.
27. Ying S, Taborda Barata L, Meng Q, Humbert M, Kay AB. The kinetics of allergen-induced transcription of messenger RNA for monocyte chemotactic protein-3 and RANTES in the skin of human atopic subjects: relationship to eosinophil, T cell, and macrophage recruitment. J Exp Med 1995;181:2153-9.
28. Varney VA, Jacobson MR, Sudderick RM, et al. Immunohistology of the nasal mucosa following allergen-induced rhinitis: identification of activated T lymphocytes, eosinophils, and neutrophils. Am Rev Respir Dis 1992;146:170-6.
29. Sedgwick JB, Calhoun WJ, Gleich GJ, et al. Immediate and late airway response of allergic rhinitis patients to segmental antigen challenge: characterization of eosinophil and mast cell mediators. Am Rev Respir Dis 1991;144:1274-81.
30. Bentley AM, Meng Q, Robinson DS, Hamid Q, Kay AB, Durham SR. Increases in activated T lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics. Am J Respir Cell Mol Biol 1993;8:35-42.
31. Walker C, Virchow JC Jr, Bruijnzeel PL, Blaser K. T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma. J Immunol 1991;146:1829-35.
32. Kitaura M, Nakajima T, Imai T, et al. Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3. J Biol Chem 1996;271:7725-30.
33. Uguccioni M, Mackay CR, Ochensberger B, et al. High expression of the chemokine receptor CCR3 in human blood basophils: role in activation by eotaxin, MCP-4, and other chemokines. J Clin Invest 1997;100:1137-43.
34. Tiffany H, Alkhatib G, Combadiere C, Berger E, Murphy P. CC chemokine receptors 1 and 3 are differentially regulated by IL-5 during maturation of eosinophilic HL-60 cells. J Immunol 1998;160:1385-92.
35. Sallusto F, Mackay CR, Lanzavecchia A. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 1997;277:2005-7.
36. Clutterbuck EJ, Sanderson CJ. Regulation of human eosinophil precursor production by cytokines: a comparison of recombinant human interleukin-1 (rhIL-1), rhIL-3, rhIL-5, rhIL-6, and rh granulocyte-macrophage colony-stimulating factor. Blood 1990;75:1774-9.