Sepsis as a modulator of adaptation to low and high carbohydrate and low and high fat intakes

European Journal of Clinical Nutrition

Volumn 53, Issue , 1999, Pages s136-s142

  Wolfe, R R ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANABOLIC AGENT; FATTY ACID; INSULIN; MUSCLE PROTEIN; TRIACYLGLYCEROL;

AEROBIC METABOLISM; CARBOHYDRATE INTAKE; CATABOLISM; CONFERENCE PAPER; CRITICAL ILLNESS; FAT INTAKE; FATTY ACID BLOOD LEVEL; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE OXIDATION; HUMAN; HYPOGLYCEMIA; LEAN BODY WEIGHT; LIPOLYSIS; MUSCLE; NUTRITIONAL SUPPORT; PHYSIOLOGY; PROTEIN SYNTHESIS; SEPSIS; STRESS;

ADAPTATION, PHYSIOLOGICAL; DIETARY CARBOHYDRATES; DIETARY FATS; ENERGY INTAKE; ENERGY METABOLISM; GLUCOSE; HUMANS; LIPOLYSIS; MUSCLES; NUTRITIONAL REQUIREMENTS; OXIDATION-REDUCTION; SEPSIS;

EID: 0032915615     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/sj.ejcn.1600754     Document Type: Article

References (52)

1. Aarsland A, Chinkes DL and Wolfe RR (1996a): Contributions of de novo synthesis of fatty acids and lipolysis to VLDL secretion during prolonged hyperglycemia/hyperinsulinemia in normal man. J. Clin. Invest. 98, 2008-2017.
2. Aarsland A, Chinkes DL, Wolfe RR, Barrow RE, Nelson SO, Pierre E and Herndon DN (1996b): Beta-blockade lowers peripheral lipolysis in burned patients receiving growth hormone: rate of hepatic VLDL triglyceride secretions remains unchanged. Ann. Surg. 23, 777-789.
3. Andres R, Cader G and Zierler KL (1956): The quantitatively minor role of carbohydrate in oxidative metabolism by skeletal muscle in intact man in the basal state: Measurements of oxygen and glucose uptake and carbon dioxide and lactate production in the forearm. J. Clin. Invest. 35, 671-682.
4. Askanazi J, Nordenstrom J, Rosenbaum SH, Elwyn DH, Hyman AI, Carpentier YA and Kinney JM (1981): Nutrition for the patient with respiratory failure: glucose versus fat. Anesthesiology 54, 373-377.
5. Baba H, Zhang X-J, Kunkel K and Wolfe RR (1994): Effect of hepatectomy on glucose metabolism in the dog. Metabolism 43, 670-676.
6. Biolo G, Fleming RYD and Wolfe RR (1995): Physiologic hyperinsulinemia stimulates protein synthesis and enhances transport of selected amino acids in human skeletal muscle. J. Clin. Invest. 95, 811-819.
7. Black PR, Brooks DC, Bessy PQ, Wolfe RR and Wilmore DW (1982): Mechanisms of insulin resistance following injury. Ann. Surg. 196, 420-435.
8. Burke JF, Wolfe RR, Mullany CJ, Matthews DE and Bier DM (1979): Glucose requirements following bum injury. Parameters of optimal glucose infusion and possible hepatic and respiratory abnormalities following excessive glucose intake. Ann. Surg. 190, 274-285.
9. Cahill GF(1970): Starvation in man. N. Engl. J. Med. 282, 668-675.
10. Calloway DH and Spector H (1954): Nitrogen balance is related to caloric and protein intake in active young men. Am. J. Clin. Nutr. 2, 405-411.
11. Cherrington AD, Stevenson RW, Steiner KE, Davis MA, Myers SR, Adkins BA, Abumrad NN and Williams PE (1987): Insulin, glucagon and glucose as regulators of hepatic glucose uptake and production in vivo. Diabetes Metab. Rev. 3, 307-332.
12. Chinkes DL, Aarsland AA, Rosenblatt JI and Wolfe RR (1996): A comparison of mass isotopomer dilution methods used to compute production of VLDL fatty acids in vivo in human subjects. Am. J. Physiol. 271, 2Pt1, E373-383.
13. Felig P (1973): The glucose-alanine cycle. Metabolism 22, 179-207.
14. Felig P, Wahren J and Hendler R (1975): Influence of oral glucose ingestion on splanchnic glucose and gluconeogenic substrate metabolism in man. Diabetes 24, 468-475.
15. Ferrando AA, Chinkes DL, Wolf SE, Matin S, Herndon DN and Wolfe RR (1999): Sub-maximal doses of insulin promote net skeletal muscle protein synthesis in patients with severe burns. Ann. Surg. (In Press).
16. Gallin JT, Kaye D and O’Leary WM (1969): Serum lipids during infection. New Engl. J. Med. 281, 1081-1086.
17. Goodenough RD and Wolfe RR (1984): Effect of total parenteral nutrition on free fatty acid metabolism in burned patients. J. Parenter. Enteral. Nutr. 8, 357-360.
18. Gore DC, Jahoor F, Hibbert JM and DeMaria EJ (1996): Lactic acidosis during sepsis is related to increased pymvate production, not deficits in tissue oxygen availability. Ann. Surg. 224, 97-102.
19. Hartl WH, Miyoshi H, Jahoor F, Klein S, Elahi D and Wolfe RR (1990): Bradykinin attenuates glucagon-induced leucine oxidation in humans. Am. J. Physiol. 259, 2Pt1, E239-E245.
20. Herndon DN, Barrow RE, Rutan TC, Minfree P, Jahoor F and Wolfe RR (1988): Effect of propranolol administration on hemodynamic and metabolic responses of burned pediatric patients. Ann. Surg. 208, 484-492.
21. 2-receptor for catecholamines. Arch. Surg. 129, 1301-1305.
22. Jahoor F, Herndon DN and Wolfe RR (1986): Role of insulin and glucagon in the response of glucose and alanine kinetics in burn-injured patients. J. Clin. Invest. 78, 807-814.
23. Jahoor F, Shangraw RE, Miyoshi H, Wallfish H, Herndon DN and Wolfe RR (1989): Role of insulin and glucose oxidation in mediating the protein catabolism of burns and spesis. Am. J. Physiol. 257, E323-E331.
24. Kelly JL, O’Sullivan C, O’Riordain M, O’Riordain D, Lyons A, Doherty J, Mannick JA and Roderick ML (1997): Is circulating endotoxin the trigger for the systemic inflammatory response syndrome seen after injury? Ann. Surg. 225, 530-543.
25. Klein S, Peters EJ, Shangraw RE and Wolfe RR (1991): Lipolytic response to metabolic stress in critically ill patients. Critical Care Medicine 19(6), 776-779.
26. Maejima K, Deitch EA and Berg R (1984): Promotion by burn stress of the translocation of bacteria from the gastrointestinal tracts of mice. Arch. Surg. 119, 166-172.
27. Miyoshi H, Shulman GI, Peters EJ, Wolfe MH, Elahi D and Wolfe RR (1988): Hormonal control of substrate cycling in humans. J. Clin. Invest. 81, 1545-1555.
28. Romijn JA, Coyle EF, Sidossis L, Gastaldelli A, Horowitz JF, Endert E and Wolfe RR (1993): Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration. Am. J. Physiol. 265, 3Pt1, E380-E391.
29. Sakurai Y, Aarsland A, Herndon DN, Chinkes DL, Pierre E, Nguyen TT, Patterson BW and Wolfe RR (1995): Stimulation of muscle protein synthesis by long-term insulin infusion in severely burned patients. Ann. Surg. 222, 282-297.
30. Shangraw RE, Jahoor F, Miyoshi H, Neff WA, Stuart CA, Herndon DN and Wolfe RR (1989): Differentiation between septic and postbum insulin resistance. Metabolism 38, 983-989.
31. Shaw JH, Klein S and Wolfe RR (1985): Assessment of alanine, urea, and glucose interrelationships in normal subjects and in patients with sepsis with stable isotopic tracers. Surgery 97, 557-568.
32. Shaw JH and Wolfe RR (1984): A conscious septic dog model with hemodynamic and metabolic responses similar to responses of humans. Surgery 95, 553-561.
33. Shaw JH and Wolfe RR (1986a): Determinations of glucose turnover and oxidation in normal volunteers and septic patients using stable and radio-isotopes: the response to glucose infusion and total parenteral feeding. Aust. N. Z. J. Surg. 56, 785-791.
34. Shaw JH and Wolfe RR (1986b): Glucose, fatty acid, and urea kinetics in patients with severe pancreatitis. The response to substrate infusion and total parenteral nutrition. Ann. Surg. 204, 665-672.
35. Shaw JH and Wolfe RR (1987): Glucose and urea kinetics in patients with early and advanced gastrointestinal cancer: the response to glucose infusion, parenteral feeding, and surgical resection. Surgery 101, 181-191.
36. Shaw JH and Wolfe RR (1989): An integrated analysis of glucose, fat, and protein metabolism in severely traumatized patients. Studies in the basal state and the response to total parenteral nutrition. Ann. Surg. 209, 63-72.
37. Sidossis LS, Mittendorfer B, Walser E, Chinkes DL and Wolfe RR (1997): Clin. Nutr. 16, abstract 0.72.
38. Sidossis LS, Stuart CA, Shulman GI, Lopaschuk GD and Wolfe RR (1996a): Glycolytic flux regulates fat oxidation by controlling the rate of fatty acid entry into the mitochondria. J. Clin. Invest. 98, 2244-2250.
39. Sidossis LS and Wolfe RR (1996b): Glucose and insulin-induced inhibition of fatty acid oxidation: The glucose-fatty acid cycle reversed. Am. J. Physiol. 270, 4Pt1, E733-E738.
40. Sidossis LS, Mittendorfer B, Walser E, Chinkes D and Wolfe RR (1998): Hyperglycemia-induced inhibition of splanchnic fatty acid oxidation increased hepatic triacylglycerol secretion. Am. J. Physiol. Endocrinol, and Metab. 38, E798-E805.
41. Streat SJ, Beddoe AH and Hill GL (1987): Aggressive nutritional support does not prevent protein loss despite fat gain in septic intensive care patients. J. Trauma 27, 262-266.
42. Stuart CA, Shangraw RE, Prince MJ, Peters EJ and Wolfe RR (1988): Bedrest-induced insulin resistance occurs primarily in muscle. Metabolism 37, 802-806.
43. Wolfe BM, Klein S, Peters EJ, Schmidt BF and Wolfe RR (1988a): Effect of elevated free fatty acids on glucose oxidation in normal humans. Metabolism 37, 323-329.
44. Wolfe BM, Walker BK and Shaul DB (1988b): Effect of total parenteral nutrition on hepatic histology. Arch. Surg. 123, 1084-1090.
45. Wolfe RR, Allsop JH and Burke JF (1979a): Glucose metabolism in man: Responses to intravenous glucose infusion. Metabolism 28, 210-220.
46. Wolfe RR, Durkot MJ, Allsop JR and Burke JF (1979b): Glucose metabolism in severely burned patients. Metabolism 28, 1031-1039.
47. Wolfe RR, Herndon DN, Jahoor F, Miyoshi H and Wolfe M (1987a): Effect of severe burn injury on substrate cycling by glucose and fatty acids. N. Engl. J. Med. 317, 403-408.
48. Wolfe RR, Herndon DN, Peters EJ, Jahoor F, Desai MH and Holland OB (1987b): Regulation of lipolysis in severely burned children. Ann. Surg. 206, 214-221.
49. Wolfe RR, Jahoor F, Herndon DN and Miyoshi H (1991): Isotopic evaluation of the metabolism of pyruvate and related substrates in normal adult volunteers and severely burned children: Effect of dichloroacetate and glucose infusion. Surgery 110, 54-67.
50. Wolfe RR, O’Donnel TF Jr, Stone MD, Richmand DA and Burke JF (1980): Investigation of factors determining the optimal glucose infusion rate in total parenteral nutrition. Metabolism 29, 892-900.
51. Wolfe RR, Shaw JH and Durkot MJ (1983): Energy metabolism in trauma and sepsis: the role of fat. Prog. Clin. Biol. Res. 3, 89-109.
52. Wolfe RR, Shaw JH and Durkot MJ (1985): Effect of sepsis on VLDL kinetics: responses in basal state and during glucose infusion. Am. J. Physiol. 248, 6 Pt 1, E732-E740.