Relevance of systemic lupus erythematosus nephritis animal models to human disease

Seminars in Nephrology

Volumn 19, Issue 1, 1999, Pages 12-24

  Foster, Mary H ^a,b,c  

^a School of Dental Medicine   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOIMMUNE DISEASE; GENOME; GENOTYPE; GLOMERULONEPHRITIS; HUMAN; IMMUNOPATHOGENESIS; LUPUS ERYTHEMATOSUS NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; AUTOIMMUNE DISEASES; DISEASE MODELS, ANIMAL; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS NEPHRITIS; MICE; MICE, INBRED MRL LPR; MICE, INBRED NZB; SENSITIVITY AND SPECIFICITY;

EID: 0032913758     PISSN: 02709295     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (84)

1. Theofilopoulos AN, Dixon FJ: Murine models of systemic lupus erythematosus. Adv Immunol 37:269-390, 1985
2. Datta SK: A search for the underlying mechanisms of systemic autoimmune disease in the NZB x SWR model. Clin Immunol Immunopathol 51:141-156, 1989
3. Kono DH, Theofilopoulos AN: Genetic contributions to SLE. J Autoimmunity 9:437-452, 1996
4. Suda T, Nagata S: Why do defects in the Fas-Fas ligand system cause autoimmunity? J Allergy Clin Immunol 100:597-101, 1997
5. cg. A novel mutant gene. Intern Rev Immunol 11:193-210, 1994
6. Morel L, Rudofsky UH, Longmate JA, et al: Polygenic control of susceptibility to murine systemic lupus erythematosus. Immunity 1:219-229, 1994
7. Izui S, Merino R, Rossati L, Iwamoto M: The role of the Yaa gene in lupus syndrome. Int Rev Immunol 11:211-230, 1994
8. Tsui FW, Tsui HW: Molecular basis of the motheaten phenotype. Immunol Rev 138:185-206, 1994
9. Yu CC, Tsui HW, Ngan BY, et al: B and T cells are not required for the viable motheaten phenotype. J Exp Med 183: 371-380, 1996
10. Kofler R, McConahey PJ, Duchosal MA, et al: An autosomal recessive gene that delays expression of lupus in BXSB mice. J Immunol 146:1375-1379, 1991
11. Kinjoh K, Kyogoku M, Good RA: Genetic selection for crescent formation yields mouse strain with rapidly progressive glomerulonephritis and small vessel vasculitis. Proc Natl Acad Sei USA 90:3413-3417, 1993
12. Goldman M, Druet P, Gleichmann E: TH2 cells in systemic autoimmunity: Insights from allogeneic diseases and chemically-induced autoimmunity. Immunol Today 12:223227, 1991
13. Griem P, Gleichmann E: Metal ion induced autoimmunity. Curr Opin Immunol 7:831-838, 1995
14. Vyse TJ, Kotzin BL: Genetic basis of systemic lupus erythematosus. Curr Opin Immunol 8:843-851, 1996
15. Wakeland EK, Morel L, Mohan C, Yui M: Genetic dissection of lupus nephritis in murine models of SLE. J Clin Immunol 17:272-281, 1997
16. Jansson L, Holmdahl R: The Y chromosome-linked "autoimmune accelerating" yaa gene suppresses collagen-induced arthritis. Eur J Immunol 24:1213-1217, 1994
17. Fisher G, Rosenberg F, Straus D, et al: Dominant interfering Fas gene-mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81:935-946, 1995
18. Drake CG, Rozzo SJ, Hirschfeld HF, et al: Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner. J Immunol 154:2441-2447, 1995
19. Drake CG, Babcock SK, Palmer E, Kotzin BL: Genetic analysis of the NZB contribution to lupus-like autoimmune disease in (NZB X NZW)F1 mice. Proc Natl Acad Sei USA 91:4062-4066, 1994
20. Vyse T, Rozzo S, Drake C, et al: Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand Black Mice. J Immunol 158:5566-5574, 1997
21. Tsao B, Cantor R, Kalunian K, et al: Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus. J Clin Invest 99:725-731, 1997
22. Watson ML, Rao JK, Gilkeson GS, et al: Genetic analysis of MRL-lpr mice: Relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci, J Exp Med 176:1645-1656, 1992
23. Vidai S, Kono DH, Theofilopoulos AN: Loci predisposing to autoimmunity in MRL-Fas Ipr and C57BL/6-FasIpr mice. J Clin Invest 101:696-702, 1998
24. Rozzo SJ, Vyse TJ, Drake CG, Kotzin BL: Effect of genetic background on the contribution of New Zealand black loci to autoimmune lupus nephritis. Proc Natl Acad Sei USA 93:15164-15168, 1996
25. Kelley VE, Roths JB: Interaction of mutant Ipr gene with background strain influences renal disease. Clin Immunol Immunopathol 37:220, 1985
26. Ghatak S, O'Keefe TL, Imanishi-Kari T, Datta SK: Selective strain distribution pattern of a germline VH gene for a pathogenic anti-DNA autoantibody family. Int Immunol 2:1003-1012, 1990
27. Hibbs ML, Tarlinton DM, Armes J, et al: Multiple defects in the immune system of fyn-deficient mice, culminating in autoimmune disease. Cell 83:301-311, 1995
28. Dang H, Geiser AG, Letterio JJ, et al: SLE-like autoantibodies and Sjogren's syndrome-like lymphoproliferation in TGF-beta knockout mice. J Immunol 155:3205-3212, 1995
29. Strasser A, Whittingham S, Vaux D, et al: Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. Proc Natl Acad Sei USA 88:8661-8665, 1991
30. Seery JP, Carroll JM, Cattell V, Watt FM: Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon y in epidermis. J Exp Med 186:1451-1459, 1997
31. Zhang L, Eddy A, Teng Y-T, et al: An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the els family of transcription factor genes. Molec Cell Biol 15:6961-6970, 1995
32. Yung R, Powers D, Johnson K, et al: Mechanisms of drug-induced lupus. II. T cells overexpressing lymphocyte function-associated antigen 1 become autoreactive and cause a lupuslike disease in syngeneic mice. J Clin Invest 97:2866-2871, 1996
33. Yung RL, Johnson KJ, Richardson BC: New concepts in the pathogenesis of drug-induced lupus. Lab Invest 73:746-759, 1995
34. Satoh M, Kumar A, Kanwar YS, Reeves WH: Antinuclear antibody production and immune complex glomerulonephritis in BALB/c mice treated with pristane. Proc Natl Acad Sei USA 92:10934-10938, 1995
35. Krieg AM: CpG DNA: A pathogenic factor in systemic lupus erythematosus? J Clin Immunol 15:284-292, 1995
36. Gilkeson GS, Ruiz P, Howell D, et al: Induction of immune-mediated glomerulonephritis in normal mice immunized with bacterial DNA. Clin Immunol Immunopath 68:283-292, 1993
37. Ray SK, Putterman C, Diamond B: Pathogenic autoantibodies are routinely generated during the response to foreign antigen: A paradigm for autoimmune disease. Proc Natl Acad Sei USA 93:2019-2024, 1996
38. Hang L, Aguado MT, Dixon FJ, Theofilopoulos AN: Induction of severe autoimmune disease in normal mice by simultaneous action of multiple immunostimulators. J Exp Med 161:423-428, 1985
39. Peng SL, Craft J: The regulation of murine lupus. Ann NY Acad Sei 815:128-138, 1997
40. Shlomchik MJ, Madaio MP, Ni D, et al: The role of B cells in Ipr/lpr-induced autoimmunity. J Exp Med 180:1295-1306, 1994
41. Peng SL, Madaio MP, Hughes DPM, et al: Murine lupus in the absence of a/3 T cells. J Immunol 156:4041-4049, 1996
42. Jevnikar A, Grusby M, Glimcher L: Prevention of nephritis in major histocampatibility complex class II-deficient MRL-Ipr mice. J Exp Med 179:1137-1143, 1994
43. Christianson GJ, Blankenburg RL, Duffy TM, et al: Beta2-microglobulin dependence of the lupus-like autoimmune syndrome of MRL-Ipr mice. J Immunol 156:4932-4939, 1996
44. Peng SL, Madaio MP, Hayday AC, Craft J: Propagation and regulation of systemic autoimmunity by 78 T cells. J Immunol 157:5689-5698, 1996
45. Radie MZ, Weigert MG: Genetic and structural evidence for antigen selection of anti-DNA antibodies. Annu Rev Immunol 12:487, 1994
46. Marion T, Krishnan M, Desai D, Jou N, Tillman D: Monoclonal anti-DNA antibodies: Structure, specificity, and biology. Methods 11:3-11, 1997
47. Desai DD, Krishnan MR, Swindle JT, Marion TN: Antigen-specific induction of antibodies against native mammalian DNA in nonautoimmune mice. J Immunol 151:1614-1626, 1993
48. Datta SK, Kaliyaperumal A: Nucleosome-driven autoimmune response in lupus. Ann NY Acad Sei 815:155-170, 1997
49. Singh RR, Kumar V, Ebling FM, et al: T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus. J Exp Med 181: 2017-2027, 1995
50. Waisman A, Ruiz PJ, Israeli E, et al: Modulation of murine systemic lupus erythematosus with peptides based on complementarity determining regions of a pathogenic antiDNA monoclonal antibody. Proc Natl Acad Sei USA 94:46204625, 1997
51. Zeng D, Dick M, Cheng L, et al: Subsets of transgenic T cells that recognize CD1 induce or prevent murine lupus: Role of cytokines. J Exp Med 187:525-536, 1998
52. Saoudi A, Castedo M, Nochy D, et al: Self reactive anti-class II Th2 cell lines derived from gold salt-injected rats trigger B cell polyclonal activation and transfer autoimmunity in CDS-dependent normal syngeneic recipients. Eur J Immunol 25:1972-1979, 1995
53. Gaynor B, Putterman C, Valadon P, et al: Peptide inhi-bition of glomerular deposition of an anti-DNA antibody. Proc NatI Acad Sei USA 94:1955-1960, 1997
54. Daikh D, Wofsy D, Imboden JB: The CD28-B7 costimulatory pathway and its role in autoimmune disease. J Leukocyte Biol 62:156-162, 1997
55. Mamula MJ, Fatehnejad S, Craft J: B-cells process and present lupus autoantigens that initiate autoimmune T-cell responses. J Immunol 152:1453-1461, 1994
56. Serreze DV, Chapman HD, Varnum DS, et al: B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: Analysis of a new "speed congenic" shock of NOD.Ig mu null mice. J Exp Med 184:2049-2053, 1996
57. Nemazee D: Promotion and prevention of autoimmunity by B lymphocytes. Curr Opin Immunol 5:866-872, 1993
58. Goodnow C, Cyster J, Hartley S, et al: Self-tolerance checkpoints in B lymphocyte development. Adv Immunol 59: 279-368, 1995
59. Erikson J, Radie MZ, Camper SA, et al: Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice. Nature 349:331-334, 1991
60. Okamoto M, Murakami M, Shimizu A, et al: A transgenic model of autoimmune hemolytic anemia. J Exp Med 175:71-79, 1992
61. Foster MH, Fitzsimons MM: Lupus-like nephrotropic autoantibodies in nonautoimmune mice harboring an anti-basement membrane/anti-DNA Ig heavy chain transgene. Molec Immunol 35:83-94, 1998
62. Roark JH, Kuntz CL, Nguyen K, et al: Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus. J Exp Med 181:1157-1167, 1995
63. Gay D, Saunders T, Camper S, Weigert M: Receptor editing: An approach by autoreactive B cells to escape tolerance. J Exp Med 177:999-1008, 1993
64. Tiegs SL, Russell DM, Nemazee D: Receptor editing in self-reactive bone marrow B cells. J Exp Med 177:1009-1020, 1993
65. Hartwell D, Levine J, Fenton M, et al: Cytokine dysregulation and the initiation of systemic autoimmunity. Immunol Letters 43:15-21, 1994
66. Ishida H, Muchamuel T, Sakaguchi S, et al: Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZBAV Fl mice. J Exp Med 179:305-310, 1994
67. Jacob CH, Van de Meide PH, McDevitt HO: In vivo treatment of (NZBXNZW)Fl lupus-like nephritis with monoclonal antibody to y Interferon. J Exp Med 166:798-803, 1987
68. Jacob CO, McDevitt HO: Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis. Nature 331:356-360, 1988
69. Santiago ML, Fossati L, Jacquet C, et al: Interleukin-4 protects against a genetically linked lupus-like autoimmune syndrome. J Exp Med 185:65-70, 1997
70. Erb KJ, Ruger B, Von Brevern M, et al: Constitutive expression of interleukin (IL)-4 in vivo causes autoimmunetype disorders in mice. J Exp Med 185:329-339, 1997
71. Peng SL, Moslehi J, Craft J: Roles of interferon-gamma and interIeukin-4 in murine lupus. J Clin Invest 99:1936-1946, 1997
72. Foster MH: Nephritogenic properties of lupus autoantibodies, in Lewis EJ (ed): Lupus Nephritis. Oxford, UK, Oxford University Press 1999.
73. Foster MH, Cizman B, Madaio MP: Nephritogenic autoantibodies in systemic lupus erythematosus: Immunochemical properties, mechanisms of immune deposition and genetic origins. Lab Invest 69:494-507, 1993
74. Vogt A, Batsford S, Morioka T: Nephritogenic antibodies in lupus nephritis. Tohoku J Exp Med 173:31-41, 1994
75. Berden JHM: Lupus nephritis. Kidney Int 52:538-558, 1997
76. Ehrenstein MR, Katz DR, Griffiths MH, et al: Human IgG anti-DNA antibodies deposit in kidneys and induce proteinuria in SCID mice. Kidney Int 48:705-711, 1995
77. Raz E, Brezis M, Rosenmann E, Eilat D: Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney. J Immunol 142:3076-3082, 1989
78. Vlahakos DV, Foster MH, Adams S, et al: Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites. Kidney Int 41:1690-1700, 1992
79. Madaio MP, Carlson J, Cataldo J, et al: Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits. J Immunol 138:2833-2894, 1987
80. Izui S, Bemey T, Shibata T, Fulpius T: IgG3 cryoglobulins in autoimmune MRL-lpr/lpr mice: Immunopathogenesis, therapeutic approaches and relevance to similar human disease. Ann Rheum Dis 52:548-54, 1993 (Suppl)
81. Kelley VR, Diaz-Gallo C, Jevnikar AM, Singer GO: Renal tubular epithelial and T cell interactions in autoimmune renal disease. Kidney Int 39:S108-115, 1993
82. Kelley VR, Moore KJ: Application of a gene transfer strategy to identify molecules that incite autoimmune kidney injury. Exp Nephrol 5:144-151, 1997
83. Diaz Gallo C, Jevnikar AM, Brennan DC, et al: Autoreactive kidney-infiltrating T-cell clones in murine lupus nephritis. Kidney Int 42:851-859, 1992
84. Meyers CM: Nephritogenic T cells in murine chronic graft-vs-host disease (cGVHD) induce interstitial injury and glomerular crescent formation. J Am Soc Nephrol 4:621, 1993 (abstr)