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Volumn 93, Issue 1, 1999, Pages 125-139

Autonomous megakaryocyte growth in essential thrombocythemia and idiopathic myelofibrosis is not related to a c-mpl mutation or to an autocrine stimulation by Mpl-L

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN;

EID: 0032913316     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v93.1.125     Document Type: Article
Times cited : (98)

References (78)
  • 1
    • 0021193583 scopus 로고
    • Role of ineffective megakaryopoiesis and megakaryocyte components
    • Castro-Malaspina H: Role of ineffective megakaryopoiesis and megakaryocyte components. Prog Clin Biol Res 154:427, 1984
    • (1984) Prog Clin Biol Res , vol.154 , pp. 427
    • Castro-Malaspina, H.1
  • 2
    • 0018825426 scopus 로고
    • The pathogenesis of myelofibrosis in myeloproliferative disorders
    • Groopman JE: The pathogenesis of myelofibrosis in myeloproliferative disorders. Ann Intern Med 92:857, 1980
    • (1980) Ann Intern Med , vol.92 , pp. 857
    • Groopman, J.E.1
  • 3
    • 0017812507 scopus 로고
    • Agnogenic myeloid metaplasia: A clonal proliferation of hematopoietic stem cells with secondary myelofibrosis
    • Jacobson RJ, Salo A, Fialkow PJ: Agnogenic myeloid metaplasia: A clonal proliferation of hematopoietic stem cells with secondary myelofibrosis. Blood 51:189, 1978
    • (1978) Blood , vol.51 , pp. 189
    • Jacobson, R.J.1    Salo, A.2    Fialkow, P.J.3
  • 5
    • 0026533908 scopus 로고
    • Cytogenetic studies of bone marrow fibroblasts cultured from patients with myelofibrosis and myeloid metaplasia
    • Wang JC, Lang HD, Lichter S, Weinstein M, Bern P: Cytogenetic studies of bone marrow fibroblasts cultured from patients with myelofibrosis and myeloid metaplasia. Br J Haematol 80:184, 1980
    • (1980) Br J Haematol , vol.80 , pp. 184
    • Wang, J.C.1    Lang, H.D.2    Lichter, S.3    Weinstein, M.4    Bern, P.5
  • 6
    • 0018163444 scopus 로고
    • Erythropoietin (EP) dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera
    • Eaves CJ, Eaves AC: Erythropoietin (EP) dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera. Blood 52:1196, 1978
    • (1978) Blood , vol.52 , pp. 1196
    • Eaves, C.J.1    Eaves, A.C.2
  • 7
    • 0018917880 scopus 로고
    • Polycythemia vera: In vitro studies of circulating erythroid progenitors
    • Lacombe C, Casadevall N, Varet B: Polycythemia vera: In vitro studies of circulating erythroid progenitors. Br J Haematol 44:189, 1980
    • (1980) Br J Haematol , vol.44 , pp. 189
    • Lacombe, C.1    Casadevall, N.2    Varet, B.3
  • 8
    • 0017856180 scopus 로고
    • Polycythemia vera. The in vitro response of normal and abnormal cell lines to erythropoietin
    • Prchal JF, Adamson JW, Murphy S, Steinmann L, Fialkow PJ: Polycythemia vera. The in vitro response of normal and abnormal cell lines to erythropoietin. J Clin Invest 61:1044, 1978
    • (1978) J Clin Invest , vol.61 , pp. 1044
    • Prchal, J.F.1    Adamson, J.W.2    Murphy, S.3    Steinmann, L.4    Fialkow, P.J.5
  • 9
    • 0023609849 scopus 로고
    • Erythropoietic colonies in a serum-free system: Results in primary proliferative polycythaemia and thrombocythaemia
    • Eridani S, Dudley JM, Sawyer BM, Pearson TC: Erythropoietic colonies in a serum-free system: Results in primary proliferative polycythaemia and thrombocythaemia. Br J Haematol 67:387, 1987
    • (1987) Br J Haematol , vol.67 , pp. 387
    • Eridani, S.1    Dudley, J.M.2    Sawyer, B.M.3    Pearson, T.C.4
  • 10
    • 0024591426 scopus 로고
    • Endogenous megakaryocyte colonies from peripheral blood in precursor cell cultures of patients with myeloproliferative disorders
    • Battegay EJ, Thomssen C, Nissen C, Gudat F, Speck B: Endogenous megakaryocyte colonies from peripheral blood in precursor cell cultures of patients with myeloproliferative disorders. Eur J Haematol 42:321, 1989
    • (1989) Eur J Haematol , vol.42 , pp. 321
    • Battegay, E.J.1    Thomssen, C.2    Nissen, C.3    Gudat, F.4    Speck, B.5
  • 11
    • 0018179449 scopus 로고
    • Increased granulocytic, erythrocytic and megakaryocytic progenitors in myelofibrosis with myeloid metaplasia
    • Chikkapa G, Carsten AL, Chanana AD, Chandra P, Cronkite EP: Increased granulocytic, erythrocytic and megakaryocytic progenitors in myelofibrosis with myeloid metaplasia. Am J Hematol 4:121, 1978
    • (1978) Am J Hematol , vol.4 , pp. 121
    • Chikkapa, G.1    Carsten, A.L.2    Chanana, A.D.3    Chandra, P.4    Cronkite, E.P.5
  • 13
    • 0020554292 scopus 로고
    • Circulating pluripotent cells in patients with myeloproliferative disorders
    • Douer D, Fabian I, Cline MJ: Circulating pluripotent cells in patients with myeloproliferative disorders. Br J Haematol 54:373, 1983
    • (1983) Br J Haematol , vol.54 , pp. 373
    • Douer, D.1    Fabian, I.2    Cline, M.J.3
  • 14
  • 15
    • 0024533993 scopus 로고
    • Characteristics of megakaryocyte colony formation in normal individuals and in primary thrombocythemia: Studies using an optimal cloning system
    • Han ZC, Brière J, Abgrall JF, Sensebe L, Parent D, Guern G: Characteristics of megakaryocyte colony formation in normal individuals and in primary thrombocythemia: Studies using an optimal cloning system. Exp Hematol 17:46, 1989
    • (1989) Exp Hematol , vol.17 , pp. 46
    • Han, Z.C.1    Brière, J.2    Abgrall, J.F.3    Sensebe, L.4    Parent, D.5    Guern, G.6
  • 16
    • 0023261950 scopus 로고
    • Colony formation by megakaryocytic progenitors in essential thrombocythemia
    • Juvonen E, Partanen S, Ruutu T: Colony formation by megakaryocytic progenitors in essential thrombocythemia. Br J Haematol 66:161, 1987
    • (1987) Br J Haematol , vol.66 , pp. 161
    • Juvonen, E.1    Partanen, S.2    Ruutu, T.3
  • 17
    • 0027468441 scopus 로고
    • Megakaryocyte and erythroid colony formation in essential thrombocythaemia and reactive thrombocytosis: Diagnostic value and correlation to complications
    • Juvonen E, Ikkala E, Oksanen K, Ruutu T: Megakaryocyte and erythroid colony formation in essential thrombocythaemia and reactive thrombocytosis: Diagnostic value and correlation to complications. Br J Haematol 83:192, 1993
    • (1993) Br J Haematol , vol.83 , pp. 192
    • Juvonen, E.1    Ikkala, E.2    Oksanen, K.3    Ruutu, T.4
  • 18
    • 0023878158 scopus 로고
    • Growth characteristics of circulating hematopoietic progenitor cells from patients with essential thrombocythemia
    • Mazur EM, Cohen JL, Bogart JL: Growth characteristics of circulating hematopoietic progenitor cells from patients with essential thrombocythemia. Blood 71:1544, 1988
    • (1988) Blood , vol.71 , pp. 1544
    • Mazur, E.M.1    Cohen, J.L.2    Bogart, J.L.3
  • 19
    • 0028109050 scopus 로고
    • Circulating megakaryocytic progenitor cells in patients with primary thrombocythaemia and reactive thrombocytosis: Results using a serum-deprived culture assay and a positive detection technique
    • Sawyer BM, Westwood NB, Pearson TC: Circulating megakaryocytic progenitor cells in patients with primary thrombocythaemia and reactive thrombocytosis: Results using a serum-deprived culture assay and a positive detection technique. Eur J Hematol 53:108, 1994
    • (1994) Eur J Hematol , vol.53 , pp. 108
    • Sawyer, B.M.1    Westwood, N.B.2    Pearson, T.C.3
  • 20
    • 0029019991 scopus 로고
    • The determination of spontaneous megakaryocyte colony formation is an unequivocal test for discrimination between essential thrombocythaemia and reactive thrombocytosis
    • Rolovic Z, Basara N, Gotic M, Sefer D, Bogdanovic A: The determination of spontaneous megakaryocyte colony formation is an unequivocal test for discrimination between essential thrombocythaemia and reactive thrombocytosis. Br J Haematol 90:326, 1995
    • (1995) Br J Haematol , vol.90 , pp. 326
    • Rolovic, Z.1    Basara, N.2    Gotic, M.3    Sefer, D.4    Bogdanovic, A.5
  • 21
    • 0023226580 scopus 로고
    • Megakaryocytic colony formation (CFU-Meg) in essential thrombocythemia : Quantitative and qualitative abnormalities of bone marrow CFU-Meg
    • Kimura H, Ishibashi T, Sato T, Matsuda S: Megakaryocytic colony formation (CFU-Meg) in essential thrombocythemia : Quantitative and qualitative abnormalities of bone marrow CFU-Meg. Am J Hematol 24:23, 1987
    • (1987) Am J Hematol , vol.24 , pp. 23
    • Kimura, H.1    Ishibashi, T.2    Sato, T.3    Matsuda, S.4
  • 22
    • 0020657930 scopus 로고
    • In vitro studies of megakaryocytopoiesis in thrombocytotic disorders of man
    • Gewirtz AM, Bruno E, Elwell J, Hoffman R: In vitro studies of megakaryocytopoiesis in thrombocytotic disorders of man. Blood 61:384, 1983
    • (1983) Blood , vol.61 , pp. 384
    • Gewirtz, A.M.1    Bruno, E.2    Elwell, J.3    Hoffman, R.4
  • 23
    • 0022455351 scopus 로고
    • Megakaryocytopoiesis in vitro of patients with essential thrombocythaemia: Effect of plasma and serum on megakaryocytic colony formation
    • Komatsu N, Suda T, Sakata Y, Eguchi M, Kaji K, Saito M, Miura Y: Megakaryocytopoiesis in vitro of patients with essential thrombocythaemia: Effect of plasma and serum on megakaryocytic colony formation. Br J Haematol 64:241, 1987
    • (1987) Br J Haematol , vol.64 , pp. 241
    • Komatsu, N.1    Suda, T.2    Sakata, Y.3    Eguchi, M.4    Kaji, K.5    Saito, M.6    Miura, Y.7
  • 24
    • 0028243412 scopus 로고
    • Spontaneous megakaryocyte colony formation in myeloproliferative disorders is not neutralizable by antibodies against IL3, IL6 and GM-CSF
    • Li Y, Hetet G, Maurer A-M, Chait Y, Dhermy D, Brière J: Spontaneous megakaryocyte colony formation in myeloproliferative disorders is not neutralizable by antibodies against IL3, IL6 and GM-CSF. Br J Haematol 87:471, 1994
    • (1994) Br J Haematol , vol.87 , pp. 471
    • Li, Y.1    Hetet, G.2    Maurer, A.-M.3    Chait, Y.4    Dhermy, D.5    Brière, J.6
  • 25
    • 0030064060 scopus 로고    scopus 로고
    • Proto-oncogene c-mpl is involved in spontaneous megakaryocytopoiesis in myeloproliferative disorders
    • Li Y, Hetet G, Kiladjan J-J, Gardin C, Grandchamp B, Brière J: Proto-oncogene c-mpl is involved in spontaneous megakaryocytopoiesis in myeloproliferative disorders. Br J Haematol 92:60, 1996
    • (1996) Br J Haematol , vol.92 , pp. 60
    • Li, Y.1    Hetet, G.2    Kiladjan, J.-J.3    Gardin, C.4    Grandchamp, B.5    Brière, J.6
  • 28
    • 0029035985 scopus 로고
    • Thrombopoietin, the primary regulator of platelet production
    • Kaushansky K: Thrombopoietin, the primary regulator of platelet production. Blood 86:419, 1995
    • (1995) Blood , vol.86 , pp. 419
    • Kaushansky, K.1
  • 31
    • 0028909690 scopus 로고
    • Thrombopoietin (c-mpl Ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin 11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro
    • Broudy V, Lin NL, Kaushansky K: Thrombopoietin (c-mpl Ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin 11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro. Blood 85:1719, 1995
    • (1995) Blood , vol.85 , pp. 1719
    • Broudy, V.1    Lin, N.L.2    Kaushansky, K.3
  • 32
    • 0029037953 scopus 로고
    • The Mpl-Ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors
    • Debili N, Wendling N, Katz A, Guichard J, Breton-Gorius J, Hunt P, Vainchenker W: The Mpl-Ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors. Blood 86:2516, 1995
    • (1995) Blood , vol.86 , pp. 2516
    • Debili, N.1    Wendling, N.2    Katz, A.3    Guichard, J.4    Breton-Gorius, J.5    Hunt, P.6    Vainchenker, W.7
  • 33
    • 0029027918 scopus 로고
    • Recombinant thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors
    • Kobayashi M, Laver JH, Kato T, Miyazaki H, Ogawa M: Recombinant thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors. Blood 86:2494, 1995
    • (1995) Blood , vol.86 , pp. 2494
    • Kobayashi, M.1    Laver, J.H.2    Kato, T.3    Miyazaki, H.4    Ogawa, M.5
  • 34
    • 0030039567 scopus 로고    scopus 로고
    • Thrombopoietin, the ligand for the Mpl receptor, synergizes with steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice
    • Ku H, Yonemura Y, Kaushansky K, Ogawa M: Thrombopoietin, the ligand for the Mpl receptor, synergizes with Steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice. Blood 87:4544, 1996
    • (1996) Blood , vol.87 , pp. 4544
    • Ku, H.1    Yonemura, Y.2    Kaushansky, K.3    Ogawa, M.4
  • 36
    • 0029912731 scopus 로고    scopus 로고
    • Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: Distinct interactions with the ligands for c-kit and FLT3
    • Ramsfjell V, Borge OJ, Veiby OP, Cardier J, Murphy MJJ, Lymari SD, Lok S, Jacobsen SEW: Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: Distinct interactions with the ligands for c-kit and FLT3. Blood 88:4481, 1996
    • (1996) Blood , vol.88 , pp. 4481
    • Ramsfjell, V.1    Borge, O.J.2    Veiby, O.P.3    Cardier, J.4    Murphy, M.J.J.5    Lymari, S.D.6    Lok, S.7    Jacobsen, S.E.W.8
  • 38
    • 0030020395 scopus 로고    scopus 로고
    • Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation
    • Nagahisa H, Nagata Y, Ohnuki T, Osada M, Nagasawa T, Abe T, Todokoro K: Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation. Blood 87:1309, 1996
    • (1996) Blood , vol.87 , pp. 1309
    • Nagahisa, H.1    Nagata, Y.2    Ohnuki, T.3    Osada, M.4    Nagasawa, T.5    Abe, T.6    Todokoro, K.7
  • 39
    • 0029835344 scopus 로고    scopus 로고
    • Constitutive expression of Mpl ligand transcripts during thrombocytopenia or thrombocytosis
    • Cohen-Solal K, Villeval JL, Titeux M, Lok S, Vainchenker W, Wendung F: Constitutive expression of Mpl ligand transcripts during thrombocytopenia or thrombocytosis. Blood 88:2578, 1996
    • (1996) Blood , vol.88 , pp. 2578
    • Cohen-Solal, K.1    Villeval, J.L.2    Titeux, M.3    Lok, S.4    Vainchenker, W.5    Wendung, F.6
  • 40
    • 0030048887 scopus 로고    scopus 로고
    • Thrombopoietin in thrombocytopenic mice: Evidence against regulation of the mRNA level and for a direct regulatory role of platelets
    • Stoffel R, Wiestner A, Skoda RC: Thrombopoietin in thrombocytopenic mice: Evidence against regulation of the mRNA level and for a direct regulatory role of platelets. Blood 87:567, 1996
    • (1996) Blood , vol.87 , pp. 567
    • Stoffel, R.1    Wiestner, A.2    Skoda, R.C.3
  • 43
    • 0029030356 scopus 로고
    • The reciprocal relationship of thrombopoietin (c-Mpl Ligand) to changes in the platelet mass during busulfaninduced thrombocytopenia in the rabbit
    • Kuter DJ, Rosenberg RD: The reciprocal relationship of thrombopoietin (c-Mpl Ligand) to changes in the platelet mass during busulfaninduced thrombocytopenia in the rabbit. Blood 85:2720, 1995
    • (1995) Blood , vol.85 , pp. 2720
    • Kuter, D.J.1    Rosenberg, R.D.2
  • 45
    • 0029956149 scopus 로고    scopus 로고
    • A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl-ligand) : Reversal of disease by bone marrow transplantation
    • Yan X-Q, Lacey D, Hill D, Chen Y, Fletcher F, Hawley RG, McNiece IK: A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl-ligand) : Reversal of disease by bone marrow transplantation. Blood 88:402, 1996
    • (1996) Blood , vol.88 , pp. 402
    • Yan, X.-Q.1    Lacey, D.2    Hill, D.3    Chen, Y.4    Fletcher, F.5    Hawley, R.G.6    McNiece, I.K.7
  • 47
    • 0031963996 scopus 로고    scopus 로고
    • Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: Insights into the pathophysiology of osteomyelofibrosis
    • Frey BM, Rafii S, Teterson M, Eaton D, Crystal RG, Moore MAS: Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: Insights into the pathophysiology of osteomyelofibrosis. J Immunol 160:691, 1998
    • (1998) J Immunol , vol.160 , pp. 691
    • Frey, B.M.1    Rafii, S.2    Teterson, M.3    Eaton, D.4    Crystal, R.G.5    Moore, M.A.S.6
  • 48
    • 0031916263 scopus 로고    scopus 로고
    • Major effects of TPO delivered by a single injection of a recombinant adenovirus on prevention of septicemia and anemia associated with myelosuppression in mice: Risk of sustained expression inducing myelofibrosis due to immunosuppression
    • Abina MA, Tulliez M, Lacout C, Debili N, Villeval J-L, Pflumio F, Wendling F, Vainchenker W, Haddada H: Major effects of TPO delivered by a single injection of a recombinant adenovirus on prevention of septicemia and anemia associated with myelosuppression in mice: Risk of sustained expression inducing myelofibrosis due to immunosuppression. Gene Ther 5:497, 1998
    • (1998) Gene Ther , vol.5 , pp. 497
    • Abina, M.A.1    Tulliez, M.2    Lacout, C.3    Debili, N.4    Villeval, J.-L.5    Pflumio, F.6    Wendling, F.7    Vainchenker, W.8    Haddada, H.9
  • 49
    • 0025674093 scopus 로고
    • A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors
    • Souyri M, Vigon I, Penciolelli JF, Heard JM, Tambourin P, Wendling F: A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors. Cell 63:1137, 1990
    • (1990) Cell , vol.63 , pp. 1137
    • Souyri, M.1    Vigon, I.2    Penciolelli, J.F.3    Heard, J.M.4    Tambourin, P.5    Wendling, F.6
  • 51
    • 0027156349 scopus 로고
    • Quantitative titration of nucleic acids by enzymatic amplification reactions run to saturation
    • Pannetier C, Delassus S, Darche S, Saucier C, Kourilsky P: Quantitative titration of nucleic acids by enzymatic amplification reactions run to saturation. Nucleic Acids Res 21:577, 1993
    • (1993) Nucleic Acids Res , vol.21 , pp. 577
    • Pannetier, C.1    Delassus, S.2    Darche, S.3    Saucier, C.4    Kourilsky, P.5
  • 52
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
    • (1987) Anal Biochem , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 56
    • 0023753816 scopus 로고
    • Evidence for pluripotent stem cell origin of idiopathic myelofibrosis: Clonal analysis of a case characterised by a N-ras gene mutation
    • Buschle M, Janssen J, Drexler H, Lyons T, Anger B, Bartram CR: Evidence for pluripotent stem cell origin of idiopathic myelofibrosis: Clonal analysis of a case characterised by a N-ras gene mutation. Leukemia 2:658, 1988
    • (1988) Leukemia , vol.2 , pp. 658
    • Buschle, M.1    Janssen, J.2    Drexler, H.3    Lyons, T.4    Anger, B.5    Bartram, C.R.6
  • 57
    • 0031019581 scopus 로고    scopus 로고
    • Clonal analysis of hematopoiesis in essential thrombocythemia: Advantages of studying T lymphocytes and platelets
    • El-Kassar N, Hetet G, Brière J, Grandchamp B: Clonal analysis of hematopoiesis in essential thrombocythemia: Advantages of studying T lymphocytes and platelets. Blood 89:128, 1997
    • (1997) Blood , vol.89 , pp. 128
    • El-Kassar, N.1    Hetet, G.2    Brière, J.3    Grandchamp, B.4
  • 60
    • 0020083461 scopus 로고
    • Erythroid progenitors in polycythemia vera. Demonstration of their hypersensitivity to erythropoietin using serum-free cultures
    • Casadevall N, Vainchenker W, Lacombe C, Vinci J, Chapman J, Breton-Gorius J, Varet B: Erythroid progenitors in polycythemia vera. Demonstration of their hypersensitivity to erythropoietin using serum-free cultures. Blood 59:447, 1982
    • (1982) Blood , vol.59 , pp. 447
    • Casadevall, N.1    Vainchenker, W.2    Lacombe, C.3    Vinci, J.4    Chapman, J.5    Breton-Gorius, J.6    Varet, B.7
  • 61
    • 0345071566 scopus 로고
    • Increased intraplatelet levels of platelet-derived growth factor and transforming growth factor-β in patients with myelofibrosis with myeloid metaplasia
    • Martyre MC, Magdelenat H, Bryckaert MC, Laine-Bridon C, Calvo F: Increased intraplatelet levels of platelet-derived growth factor and transforming growth factor-β in patients with myelofibrosis with myeloid metaplasia. Br J Haematol 88:9, 1991
    • (1991) Br J Haematol , vol.88 , pp. 9
    • Martyre, M.C.1    Magdelenat, H.2    Bryckaert, M.C.3    Laine-Bridon, C.4    Calvo, F.5
  • 62
    • 0028832719 scopus 로고    scopus 로고
    • Point mutations within a dimer interface homology domain of C-Mpl induce constitutive receptor activity and tumorigenicity
    • Alexander WS, Metcalf D, Dunn AR: Point mutations within a dimer interface homology domain of C-Mpl induce constitutive receptor activity and tumorigenicity. EMBO J 14:5569, 1996
    • (1996) EMBO J , vol.14 , pp. 5569
    • Alexander, W.S.1    Metcalf, D.2    Dunn, A.R.3
  • 64
    • 0027215519 scopus 로고
    • Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis
    • de La Chapelle A, Traskelin A, Juvonen E: Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis. Proc Natl Acad Sci USA 90:1980, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1980
    • De La Chapelle, A.1    Traskelin, A.2    Juvonen, E.3
  • 66
    • 0030986297 scopus 로고    scopus 로고
    • Familial erythrocytosis associated with a short deletion in the erythropoietin receptor gene
    • Arcasoy MO, Degar BA, Harris KW, Forget BG: Familial erythrocytosis associated with a short deletion in the erythropoietin receptor gene. Blood 89:4628, 1997
    • (1997) Blood , vol.89 , pp. 4628
    • Arcasoy, M.O.1    Degar, B.A.2    Harris, K.W.3    Forget, B.G.4
  • 67
    • 0023945705 scopus 로고
    • Transient suppression of clonal hemopoiesis associated with pregnancy in a patient with a myeloproliferative disorder
    • Turhan AG, Humphries RK, Cashman JD, Cuthbert DA, Eaves CJ, Eaves CA: Transient suppression of clonal hemopoiesis associated with pregnancy in a patient with a myeloproliferative disorder. J Clin Invest 81:1990, 1988
    • (1988) J Clin Invest , vol.81 , pp. 1990
    • Turhan, A.G.1    Humphries, R.K.2    Cashman, J.D.3    Cuthbert, D.A.4    Eaves, C.J.5    Eaves, C.A.6
  • 69
    • 0003350616 scopus 로고    scopus 로고
    • Analysis of the thrombopoietin receptor (Mpl) on platelets from normal and essential thrombocythemic (ET) patients
    • Li J, Xia Y, Kuter DJ: Analysis of the thrombopoietin receptor (Mpl) on platelets from normal and essential thrombocythemic (ET) patients. Blood 88:545, 1996
    • (1996) Blood , vol.88 , pp. 545
    • Li, J.1    Xia, Y.2    Kuter, D.J.3
  • 70
    • 2642609475 scopus 로고    scopus 로고
    • Impaired expression of the thrombopoietin receptor by platelets from patients with Polycythemia Vera
    • Moliterno AR, Hankins WD, Spivak JL: Impaired expression of the thrombopoietin receptor by platelets from patients with Polycythemia Vera. N Engl J Med 338:572, 1998
    • (1998) N Engl J Med , vol.338 , pp. 572
    • Moliterno, A.R.1    Hankins, W.D.2    Spivak, J.L.3
  • 71
    • 0031975482 scopus 로고    scopus 로고
    • An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia
    • Wiestner A, Schlemper RJ, van der Maas APC, Skoda RC: An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia. Nat Genet 18:49, 1998
    • (1998) Nat Genet , vol.18 , pp. 49
    • Wiestner, A.1    Schlemper, R.J.2    Van Der Maas, A.P.C.3    Skoda, R.C.4
  • 72
    • 0029810923 scopus 로고    scopus 로고
    • Constitutive activation of STATS by the BCR-ABL oncogene in chronic myelogenous leukemia
    • Shuai K, Halpern J, ten Hoeve J, Sawyers CL: Constitutive activation of STATS by the BCR-ABL oncogene in chronic myelogenous leukemia. Oncogene 13:247, 1996
    • (1996) Oncogene , vol.13 , pp. 247
    • Shuai, K.1    Halpern, J.2    Ten Hoeve, J.3    Sawyers, C.L.4
  • 74
    • 0029912083 scopus 로고    scopus 로고
    • Soluble thrombopoietin receptor (Mpl) and granulocyte colony-stimulating factor receptor directly stimulate proliferation of primitive hematopoietic progenitors of mice in synergy with steel factor or the ligand for Flt3/Flk2
    • Ku H, Hirayama F, Kato T, Miyasaki H, Aritomi M, Ota Y, D'Andrea A, Lyman SD, Ogawa M: Soluble thrombopoietin receptor (Mpl) and granulocyte colony-stimulating factor receptor directly stimulate proliferation of primitive hematopoietic progenitors of mice in synergy with Steel factor or the ligand for Flt3/Flk2. Blood 88:4124, 1996
    • (1996) Blood , vol.88 , pp. 4124
    • Ku, H.1    Hirayama, F.2    Kato, T.3    Miyasaki, H.4    Aritomi, M.5    Ota, Y.6    D'Andrea, A.7    Lyman, S.D.8    Ogawa, M.9
  • 78
    • 0030962275 scopus 로고    scopus 로고
    • Polycythemia vera. V enhanced proliferation and phosphorylation due to vanadate are diminished in polycythemia vera erythroid progenitor cells: A possible defect of phosphatase activity in polycythemia vera
    • Dai CH, Krantz SB, Sawyer ST: Polycythemia vera. V Enhanced proliferation and phosphorylation due to vanadate are diminished in polycythemia vera erythroid progenitor cells: A possible defect of phosphatase activity in polycythemia vera. Blood 89:3574, 1997
    • (1997) Blood , vol.89 , pp. 3574
    • Dai, C.H.1    Krantz, S.B.2    Sawyer, S.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.