Intestinal tumorigenesis in the Apc1638N mouse treated with aspirin and resistant starch for up to 5 months

Carcinogenesis

Volumn 20, Issue 5, 1999, Pages 805-810

  Williamson, Sophia L H ^a   Kartheuser, Alex ^b   Coaker, Julie ^c   Kooshkghazi, Mahshid Dehghan ^c   Fodde, Riccardo ^d   Burn, John ^e   Mathers, John C ^c  

^a ROYAL VICTORIA INFIRMARY   (United Kingdom)

^b CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d Department of Human Genetics   (Netherlands)

^e NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTINEOPLASTIC AGENT; FAT; PROTEIN; STARCH; SUCROSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DIET; DIETARY FIBER; FEMALE; INTESTINE CANCER; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

EID: 0032903863     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.5.805     Document Type: Article

References (64)

1. Polakis,P. (1997) The adenomatous polyposis coli (APC) tumor suppressor. Biochim. Biophys. Acta, 1332, F127-F147.
2. Kartheuser,A., Detry,R., West,S. et al. (1995) The technical background of familial adenomatous polyposis - history, epidemiology, diagnosis and treatment. Acta Gastro-Ent. Belg., 58, 252-266.
3. Iwama,T., Mishima,Y. and Utsunomiya,J. (1993) The impact of familial adenomatous polyposis on the tumorigenesis and mortality at the several organs - its rational treatment. Ann. Surg, 217, 101-108.
4. Nishisho,I., Nakamura,Y., Miyohsi,Y, et al. (1991) Mutations of chromosome 5Q21 genes in FAP and colorectal cancer patients. Science, 253, 665-669.
5. Smith,K.J., Johnson,K.A., Bryan,T.M. et al. (1993) The APC gene product in normal and tumor cells. Proc. Natl Acad. Sci. USA, 90, 2846-2850.
6. Nathke,I.S., Adams,C.L., Polakis,P., Sellin,J.H. and Nelson,W.J. (1996) The adenomatous polyposis coli tumor suppressor protein localises to plasma membrane sites involved in active cell migration. J. Cell Biol., 134, 165-179.
7. Peifer,M. (1996) Regulating cell proliferation: As easy as APC. Science, 272, 974-975.
8. Baeg,G.H., Matsumine,A., Kuroda,T., Bhattacharjee,R.N., Miyashiro,I., Toyoshima,K. and Akiyama,T. (1995) The tumor suppressor gene product APC blocks cell cycle progression from G(0)/G(1) to S phase. EMBO J., 14, 5618-5625.
9. Browne,S.J., Williams,A.C., Hague.A., Butt,A.J. and Paraskeva,C. (1994) Loss of APC protein expressed by human colonic epithelial cells and the appearance of a specific low-molecular-weight form is associated with apoptosis in vitro. Int. J. Cancer, 59, 56-64.
10. Morin,P.J., Vogelstein,B. and Kinzler,K.W. (1996) Apoptosis and APC in colorectal tumorigenesis. Proc. Natl Acad. Sci. USA, 93, 7950-7954.
11. Powell,S.M., Zilz,N., Beazer-Barclay,Y., Bryan,T.M., Hamilton,S.R., Thibodeau,S.N., Vogelstein,B. and Kinzler,K.W. (1992) APC mutations occur early during colorectal tumorigenesis. Nature, 359, 235-237.
12. Prescott,S.M. and White,R.L. (1996) Self-promotion? Intimate connections between APC and prostaglandin H synthase-2. Cell, 87, 783-786.
13. Levy,D.B., Smith,K.J., Beazer-Barclay,Y., Hamilton,S.R., Vogelstein,B. and Kinzler,K.W. (1994) Inactivation of both APC alleles in human and mouse tumors. Cancer Res., 54, 5953-5958.
14. Jen,J., Powell,S.M., Papadopoulos,N., Smith,K.J., Hamilton,S.R., Vogelstein,B. and Kinzler,K.W. (1994) Molecular determinants of dysplasia in colorectal lesions. Cancer Res., 54, 5523-5526.
15. Tsao,J.-I. and Shibata,D. (1994) Further evidence that one of the earliest alterations in colorectal carcinogenesis involves APC. Am. J. Pathol., 145, 531-534.
16. Kinzler,K.W. and Vogelstein,B. (1996) Lessons from hereditary colorectal cancer. Cell, 87, 159-170.
17. World Cancer Research Fund and American Institute for Cancer Research. (1997) Food, Nutrition and the Prevention of Cancer: a Global Prospective. American Institute for Cancer Research, Washington, DC.
18. Department of Health (1998) Nutritional Aspects of the Development of Cancer. Report on Health and Social Subjects, no. 48. The Stationery Office, London, UK.
19. Doll,R. and Peto,R. (1981) The causes of cancer - quantitative estimates of avoidable risks of cancer in the United States today. J. Natl Cancer Inst., 66, 1191-1308.
20. Bingham,S.A. (1996) Epidemiology and mechanisms relating diet to risk of colorectal cancer. Nutr. Res. Rev., 9, 197-239.
21. Cassidy,A., Bingham,S.A. and Cummings,J.H. (1994) Starch intake and colorectal cancer risk: an international comparison. Br. J. Cancer, 69, 937-942.
22. Macfarlane,G.T. and Gibson,G.R. (1995) Microbiological aspects of the production of short chain fatty acids in the large bowel. In Cummings,J.H. Rombeau,J.L. and Sakata,T. (eds) Physiological and Clinical Aspects of Short Chain Fatty Acids. Cambridge University Press, Cambridge, UK, pp. 87-105.
23. Roediger,W.E.W. (1982) Utilization of nutrients by isolated epithelial cells of the rat colon. Gastroenterology, 83, 424-429.
24. Kruh,J., Defer,N. and Tichonicky,L. (1995) Effects of butyrate on cell proliferation and gene expression. In Cummings,J.H. Rombeau J.L. and Sakata,T. (eds) Physiological and Clinical Aspects of Short Chain Fatty Acids. Cambridge University Press, UK, pp. 275-288.
25. Hague,A., Elder,D.J.E., Hicks,D.J. and Paraskeva,C. (1995) Apoptosis in colorectal tumour cells: induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate. Int. J. Cancer, 60, 400-406.
26. Singh,B., Halestrap,A.P. and Paraskeva,C. (1997) Butyrate can act as a stimulator of growth or inducer of apoptosis in human colonic epithelial cell lines depending on the presence of alternative energy sources. Carcinogenesis, 18, 1265-1270.
27. Young,G.P. and Gibson,P.R. (1995) Butyrate and the human cancer cell. In Cummings,J.H., Rombeau,J.L. and Sakata,T. (eds) Physiological and Clinical Aspects of Short Chain Fatty Acids. Cambridge University Press, Cambridge, UK, pp. 319-335.
28. D'Argenio,G., Cosenza,V., Delle Cave,M., Iovino,P., Della Valle,N., Lombardi,G. and Mazzacca,G. (1996) Butyrate enemas in experimental colitis and protection against large bowel cancer in a rat model. Gastroenterology, 110, 1727-1734.
29. Giovannucci,E., Rimm,E.B., Stampfer,M.J., Colditz,G.A., Ascherio,A. and Willett,W.C. (1994) Aspirin use and the risk for colorectal cancer and adenoma in male health professionals. Ann. Int. Med., 121, 241-246.
30. Giovannucci,E., Egan,K.M., Hunter,D.J., Stampfer,M.J., Colditz,G.A., Willett,W.C. and Speizer,F.E. (1995) Aspirin and the risk of colorectal cancer in women. N. Engl. J. Med., 333, 609-614.
31. Thun,M.J., Namboodiri,M.M. and Heath,C.W. (1991) Aspirin use and reduced risk of fatal colon cancer. N. Engl. J. Med., 325, 1593-1596.
32. Spagnesi,M.T., Tonelli,F., Dolara,P., Caderni,G., Valanzano,R., Anastasi,A. and Bianchini,F. (1994) Rectal proliferation and polyp occurrence in patients with familial adenomatous polyposis after sulindac treatment. Gastroenterology, 106, 362-366.
33. Waddell,W.R. and Loughry,R.W. (1983) Sulindac for polyposis of the colon. J. Surg Oncol, 24, 83-87.
34. Pasricha,P.J., Bedi,A., O'Connor,K., Rashid,A., Akhtar,A.J., Zahurak,M.L., Piantadosi,S., Hamilton,S.R. and Giardiello,F.M. (1995) The effects of sulindac on colorectal proliferation and apoptosis in familial adenomatous polyposis. Gastroenterology, 109, 994-998.
35. Giardiello,F.M., Offerhaus,J.A., Tersmette,A.C., Hylind,L.M., Krush,A.J., Brensinger,J.D., Booker,S.V. and Hamilton,S.R. (1996) Sulindac induced regression of colorectal adenomas in familial adenomatous polyposis: evaluation of predictive factors. Gut, 38, 578-581.
36. Matsuhashi,N., Nakajima,A., Fukushima,Y., Yazaki,Y. and Oka,T. (1997) Effects of sulindac on sporadic colorectal adenomatous polyps. Gut, 40, 344-349.
37. Min mouse model by the non-steroidal anti-inflammatory drug piroxicam. Cancer Res., 56, 710-714.
38. Boolbol,S.K., Dannenberg,A.J., Chadburn,A. et al. (1996) Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis. Cancer Res., 56, 2556-2560.
39. Moorghen,M., Ince,P., Finney,K.J., Sunter,J.P., Appleton,D.R. and Watson,A.J. (1988) A protective effect of sulindac against chemically-induced primary colonic tumours in mice. J. Pathol., 156, 341-347.
40. Davis,A.E. and Patterson,F. (1994) Aspirin reduces the incidence of colonic carcinoma in the dimethylhydrazine rat animal model. Aust. N. Z. J. Med., 24, 301-303.
41. Sano,H., Kawahito,Y., Wilder,R.L. et al. (1995) Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res., 55, 3785-3789.
42. Williams,C.S., Luongo,C., Radhika,A., Zhang,T., Lamps,L.W., Nanney,L.B., Beauchamp,R.D. and DuBois,R.N. (1996) Elevated cyclooxygenase-2 levels in Min mouse adenomas. Gastroenterology, 111, 1134-1140.
43. Elder,D.J.E. and Paraskeva,C. (1997). NSAIDs to prevent colorectal cancer: a question of sensitivity. Gastroenterology, 113, 1999-2003.
44. Fodde,R., Edelmann,W., Yang,K. et al. (1994) A targeted chain-termination mutation in the mouse APC gene results in multiple intestinal tumors. Proc. Natl Acad. Sci. USA. 91, 8969-8973.
45. Yang,K., Edelmann,W., Fan,K.H., Lau,K., Kolli,V., Fodde,R., Khan,P.M., Kucherlapati,R. and Lipkin,M. (1997) A mouse model of human familial adenomatous polyposis. J. Exp. Zool., 277, 245-254.
46. Fenogli-Preiser,C.M. and Noffsinger,A.E. (1995). Epithelial tumours and tumour-like conditions of the large intestine. In Whitehead,R. (ed.) Gastrointestinal and Oesophageal Pathology, 2nd edn. Churchill Livingstone, Edinburgh, pp. 869-875.
47. Van Munster,I.P., Tangerman,A. and Nagengast,F.M. (1994) Effect of resistant starch on colonic fermentation, bile acid metabolism and mucosal proliferation. Dig. Dis. Sci., 39, 834-842.
48. Sakamoto,J., Nakaji,S., Sugawara,K., Iwane,S. and Munakata,A. (1996) Comparison of resistant starch with cellulose diet on 1,2-dimethylhydrazine - induced colonic carcinogenesis in rats. Gastroenterology, 110, 116-120.
49. Dexter,D.L., Lev,R., McKendall,G.R., Mitchell,P. and Calabres,P. (1984) Sodium butyrate-induced alteration of growth properties and glycogen levels in cultured human colon carcinoma cells. Histochem. J., 16,137-149.
50. Young,G.P., McIntyre,A., Albert,V., Folini,M., Muir,J.G. and Gibson,P.R. (1996) Wheat bran suppresses potato starch-potentiated colorectal tumorigenesis at the aberrant crypt stage in a rat model. Gastroenterology, 110, 508-514.
51. Cassand,P., Maziere,S., Champ,M., Meflah,K., Bornet,F. and Narbonne,J.F. (1997). Effects of resistant starch- and vitamin A-supplemented diets on the promotion of precursor lesions of colon cancer in rats. Nutr. Cancer, 27, 53-59.
52. Caderni,G., Bianchini,F., Mancina,A., Spagnesi,M.T. and Dolara,P. (1991) Effect of dietary carbohydrates on the growth of dysplastic crypt foci in the colon of rats treated with 1,2-dimethylhydrazine. Cancer Res., 51, 3721-3725.
53. Thorup,I., Meyer,O. and Kristiansen,E. (1995) Effect of potato starch, cornstarch and sucrose on aberrant crypt foci in rats exposed to azoxymethane. Anticancer Res., 15, 2101-2105.
54. Cummings,J.H. (1997) The Large Intestine in Nutrition and Disease. Institut Danone, Brussels.
55. Beazer-Barclay,Y., Levy,D.B., Moser,A.R., Dove,W.F., Hamilton,S.R., Vogelstein,B. and Kinzler,K.W. (1996) Sulindac suppresses tumorigenesis in the Min mouse. Carcinogenesis, 17, 1757-1760.
56. Morgan,G. (1996) Non-steroidal inflammatory drugs and the chemoprevention of colorectal and oesophageal cancers. Gut, 38, 646-648.
57. Marnett,L.J. (1992), Aspirin and the potential role of prostaglandins in colon cancer. Cancer Res., 52, 5575-5589.
58. Piazza,G.A., Rahm,A.L.K., Krutzsch,M. et al. (1995) Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis. Cancer Res., 55, 3110-3116.
59. Shiff,S.J., Koutsos,M.I., Qiao,L. and Rigas,B. (1996) Non-steroidal anti-inflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: effects on cell cycle and apoptosis. Exp. Cell Res., 222, 179-188.
60. Levine,A.J. (1997) p53, the cellular gatekeeper for growth and division. Cell, 88, 323-331.
61. Doll,R. (1990) An overview of the epidemiological evidence linking diet and cancer. Proc. Nutr. Soc., 49, 119-131.
62. Hylla,S., Gostner,A., Dusel,G., Anger,H., Bartram,H.-P., Christl,S.U., Kasper,H. and Scheppach,W. (1998) Effects of resistant starch on the colon in healthy volunteers: possible implications for cancer prevention. Am. J. Clin. Nutr., 67, 136-142.
63. Barnes,C.J. and Lee,M. (1998) Chemoprevention of spontaneous intestinal adenomas in the adenomatous polyposis coli Min mouse model with aspirin. Gastroenterology, 114, 873-877.
64. Smits,R., Van Oordt,W.V.D., Luz,A., Zurcher,C., Jagmohan-Changur,S., Breukel,C., Khan,P.M. and Fodde,R. (1998) Apc 1638N: a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts. Gastroenterology, 114, 275-283.