-
1
-
-
0023754423
-
Discovery, biochemistry and biology of lovastatin
-
Alberts AW (1988) Discovery, biochemistry and biology of lovastatin. Am J Cardiol 62:10J-15J.
-
(1988)
Am J Cardiol
, vol.62
-
-
Alberts, A.W.1
-
2
-
-
0028843657
-
Effect of oxysterol treatment on cholesterol biosynthesis and reactive astrocyte proliferation in injured rat brain cortex
-
Bochelen D, Mersel M, Behr P, Lutz P and Kupferberg A (1995) Effect of oxysterol treatment on cholesterol biosynthesis and reactive astrocyte proliferation in injured rat brain cortex. J Neurochem 65:2194-2200.
-
(1995)
J Neurochem
, vol.65
, pp. 2194-2200
-
-
Bochelen, D.1
Mersel, M.2
Behr, P.3
Lutz, P.4
Kupferberg, A.5
-
3
-
-
0029054750
-
Drug-induced apoptosis is not necessarily dependent on macromolecular synthesis or proliferation in the p53-negative human prostate cancer cell line PC-3
-
Borner MM, Myers CE, Sartor O, Sei Y, Toko T and Trepel JB and Schneider E (1995) Drug-induced apoptosis is not necessarily dependent on macromolecular synthesis or proliferation in the p53-negative human prostate cancer cell line PC-3. Cancer Res 55:2122-2128.
-
(1995)
Cancer Res
, vol.55
, pp. 2122-2128
-
-
Borner, M.M.1
Myers, C.E.2
Sartor, O.3
Sei, Y.4
Toko, T.5
Trepel, J.B.6
Schneider, E.7
-
4
-
-
0027771498
-
Inhibition of protein synthesis in baby-hamster kidney cells blocks oxysteroi-mediated suppression of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA at a post-transcriptional level
-
Choi JW, Lundquist EN and Peffley DM (1993) Inhibition of protein synthesis in baby-hamster kidney cells blocks oxysteroi-mediated suppression of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA at a post-transcriptional level. Biochem J 296:859-866.
-
(1993)
Biochem J
, vol.296
, pp. 859-866
-
-
Choi, J.W.1
Lundquist, E.N.2
Peffley, D.M.3
-
5
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P and Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
6
-
-
0028955639
-
Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis
-
Chow SC, Peters I and Orrenius S (1995) Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis. Exp Cell Res 216:149-159
-
(1995)
Exp Cell Res
, vol.216
, pp. 149-159
-
-
Chow, S.C.1
Peters, I.2
Orrenius, S.3
-
7
-
-
0026802011
-
Hormone-regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle
-
Colombel M, Olsson CA, Ng PY and Buttyan R (1992) Hormone-regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle. Cancer Res 52:4313-4319.
-
(1992)
Cancer Res
, vol.52
, pp. 4313-4319
-
-
Colombel, M.1
Olsson, C.A.2
Ng, P.Y.3
Buttyan, R.4
-
8
-
-
0029050456
-
Cell death: Current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo
-
Columbano A (1995) Cell death: Current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo. J Cell Biochem 58:181-190.
-
(1995)
J Cell Biochem
, vol.58
, pp. 181-190
-
-
Columbano, A.1
-
10
-
-
0030899235
-
Neuroprotective action of cycloheximide involves induction of Bcl-2 and antioxidant pathways
-
Furukawa K, Estus S, Fu W, Mark RJ and Mattson MP (1997) Neuroprotective action of cycloheximide involves induction of Bcl-2 and antioxidant pathways. J Cell Biol 136:1137-1149.
-
(1997)
J Cell Biol
, vol.136
, pp. 1137-1149
-
-
Furukawa, K.1
Estus, S.2
Fu, W.3
Mark, R.J.4
Mattson, M.P.5
-
11
-
-
0030781018
-
Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way
-
Gamen S, Anel A, Lasierra P, Alava MA, Martinez-Lorenzo MJ, Pineiro A and Naval J (1997) Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way. FEBS Lett 417:360-364.
-
(1997)
FEBS Lett
, vol.417
, pp. 360-364
-
-
Gamen, S.1
Anel, A.2
Lasierra, P.3
Alava, M.A.4
Martinez-Lorenzo, M.J.5
Pineiro, A.6
Naval, J.7
-
12
-
-
0026689242
-
Apoptosis: A different type of cell death
-
Gerschenson LE and Rotello RJ (1992) Apoptosis: A different type of cell death. FASEB J 6:2450-2455.
-
(1992)
FASEB J
, vol.6
, pp. 2450-2455
-
-
Gerschenson, L.E.1
Rotello, R.J.2
-
13
-
-
0025120211
-
Regulation of mevalonate pathway
-
Goldstein JL and Brown MS (1990) Regulation of mevalonate pathway. Nature (London) 343:425-430.
-
(1990)
Nature (London)
, vol.343
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
14
-
-
0029814868
-
Comet assay to detect nitric oxide-dependent DNA damage in mammalian cells
-
Green MH, Lowe JE, Delaney CA and Green IC (1996) Comet assay to detect nitric oxide-dependent DNA damage in mammalian cells. Methods Enzymol 269:243-266.
-
(1996)
Methods Enzymol
, vol.269
, pp. 243-266
-
-
Green, M.H.1
Lowe, J.E.2
Delaney, C.A.3
Green, I.C.4
-
15
-
-
0029670477
-
kip1 accumulation during the cell cycle
-
kip1 accumulation during the cell cycle. Science (Wash DC) 271:1861-1864.
-
(1996)
Science (Wash DC)
, vol.271
, pp. 1861-1864
-
-
Hengst, L.1
Reed, S.I.2
-
16
-
-
0029797603
-
Glucose promotes survival of rat pancreatic β cells by activating synthesis of proteins which suppress a constitutive apoptotic program
-
Hoorens A, Van de Casteele M, Kloppel G and Pipeleers D (1996) Glucose promotes survival of rat pancreatic β cells by activating synthesis of proteins which suppress a constitutive apoptotic program. J Clin Invest 98:1568-1574.
-
(1996)
J Clin Invest
, vol.98
, pp. 1568-1574
-
-
Hoorens, A.1
Van De Casteele, M.2
Kloppel, G.3
Pipeleers, D.4
-
17
-
-
0027340547
-
Release from G1 growth arrest by transforming growth factor beta 1 requires cellular ras activity
-
Howe PH, Dobrowolski SF, Reddy KB and Stacey DW (1993) Release from G1 growth arrest by transforming growth factor beta 1 requires cellular ras activity. J Biol Chem 268:21448-21452.
-
(1993)
J Biol Chem
, vol.268
, pp. 21448-21452
-
-
Howe, P.H.1
Dobrowolski, S.F.2
Reddy, K.B.3
Stacey, D.W.4
-
18
-
-
0028596288
-
Lovastatin induces growth inhibition and apoptosis in human malignant glioma cells
-
Jones KD, Couldwell WT, Hinton DR, Su Y, He S, Anker L and Law RE (1994) Lovastatin induces growth inhibition and apoptosis in human malignant glioma cells. Biochem Biophys Res Commun 205:1681-1687.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1681-1687
-
-
Jones, K.D.1
Couldwell, W.T.2
Hinton, D.R.3
Su, Y.4
He, S.5
Anker, L.6
Law, R.E.7
-
19
-
-
0019140920
-
Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase
-
Kita T, Brown MS and Goldstein JL (1980) Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase. J Clin Invest 66:1094-1100.
-
(1980)
J Clin Invest
, vol.66
, pp. 1094-1100
-
-
Kita, T.1
Brown, M.S.2
Goldstein, J.L.3
-
20
-
-
0026000557
-
Isoprenoids and astroglial cell cycling: Diminished mevalonate availability and inhibition of dolichol-linked glycoprotein synthesis arrest cycling through distinct mechanism
-
Langan TJ and Slater MC (1991) Isoprenoids and astroglial cell cycling: Diminished mevalonate availability and inhibition of dolichol-linked glycoprotein synthesis arrest cycling through distinct mechanism. J Cell Physiol 149:284-292.
-
(1991)
J Cell Physiol
, vol.149
, pp. 284-292
-
-
Langan, T.J.1
Slater, M.C.2
-
21
-
-
0026459282
-
Simultaneous analysis of immunophenotype and apoptosis of murine thymocytes by single laser flow cytometry
-
Lyons AB, Samuel K, Sanderson A and Maddy AH (1992) Simultaneous analysis of immunophenotype and apoptosis of murine thymocytes by single laser flow cytometry. Cytometry 13:809-821.
-
(1992)
Cytometry
, vol.13
, pp. 809-821
-
-
Lyons, A.B.1
Samuel, K.2
Sanderson, A.3
Maddy, A.H.4
-
22
-
-
0028891783
-
Apoptosis, oncosis, and necrosis
-
Majno G and Joris I (1995) Apoptosis, oncosis, and necrosis. Am J Pathol 146:3-15.
-
(1995)
Am J Pathol
, vol.146
, pp. 3-15
-
-
Majno, G.1
Joris, I.2
-
23
-
-
0029738086
-
Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell cycle-independent toxicity
-
Morris EJ and Geller HM (1996) Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell cycle-independent toxicity. J Cell Biol 134:757-770.
-
(1996)
J Cell Biol
, vol.134
, pp. 757-770
-
-
Morris, E.J.1
Geller, H.M.2
-
24
-
-
0031582209
-
Inhibition of proliferation of human smooth muscle cells by various HMG-CoA reductase inhibitors; comparison with other human cell types
-
Négre-Aminou P, van Vliet AK, van Erick M, van Thiel CF, van Leeuwen REW and Cohen LH (1997) Inhibition of proliferation of human smooth muscle cells by various HMG-CoA reductase inhibitors; comparison with other human cell types. Biochim Biophys Acta 1345:259-268.
-
(1997)
Biochim Biophys Acta
, vol.1345
, pp. 259-268
-
-
Négre-Aminou, P.1
Van Vliet, A.K.2
Van Erick, M.3
Van Thiel, C.F.4
Van Leeuwen, R.E.W.5
Cohen, L.H.6
-
25
-
-
0027469404
-
Lovastatin inhibits proliferation of rat mesangial cells
-
O'Donnell MP, Kasiske BL, Kim Y, Atluru D and Keane WF (1993) Lovastatin inhibits proliferation of rat mesangial cells. J Clin Invest 91:83-87.
-
(1993)
J Clin Invest
, vol.91
, pp. 83-87
-
-
O'Donnell, M.P.1
Kasiske, B.L.2
Kim, Y.3
Atluru, D.4
Keane, W.F.5
-
26
-
-
0028307941
-
Inhibition of isoprenoid biosynthesis induces apoptosis in human promyelocytic HL-60 cells
-
Pérez-Sala D and Mollinedo F (1994) Inhibition of isoprenoid biosynthesis induces apoptosis in human promyelocytic HL-60 cells. Biochem Biophys Res Commun 199:1209-1215.
-
(1994)
Biochem Biophys Res Commun
, vol.199
, pp. 1209-1215
-
-
Pérez-Sala, D.1
Mollinedo, F.2
-
27
-
-
0031438501
-
Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages
-
Pahan K, Sheikh FG, Namboodiri MS and Singh I (1997) Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J Clin Invest 100:2671-2679.
-
(1997)
J Clin Invest
, vol.100
, pp. 2671-2679
-
-
Pahan, K.1
Sheikh, F.G.2
Namboodiri, M.S.3
Singh, I.4
-
28
-
-
0027971199
-
Induction of endothelial cell apoptosis by TNFα: Modulation by inhibitors of protein synthesis
-
Polunovsky VA, Wendt CH, Ingbar DH, Peterson MS and Bitterman PB (1994) Induction of endothelial cell apoptosis by TNFα: Modulation by inhibitors of protein synthesis. Exp Cell Res 214:584-594.
-
(1994)
Exp Cell Res
, vol.214
, pp. 584-594
-
-
Polunovsky, V.A.1
Wendt, C.H.2
Ingbar, D.H.3
Peterson, M.S.4
Bitterman, P.B.5
-
29
-
-
0031938280
-
Nuclear factor-κB contributes to excitotoxin-induced apoptosis in rat striatum
-
Qin Z-H, Wang Y, Nakai M and Chase TN (1998) Nuclear factor-κB contributes to excitotoxin-induced apoptosis in rat striatum. Mol Pharmacol 53:33-42.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 33-42
-
-
Qin, Z.-H.1
Wang, Y.2
Nakai, M.3
Chase, T.N.4
-
30
-
-
0020664259
-
The dual role of mevalonate in the cell cycle
-
Quesney-Huneeus V, Galick HA, Siperstein MD, Erickson SK, Spencer TA and Nelson JA (1983) The dual role of mevalonate in the cell cycle. J Biol Chem 258:378-385.
-
(1983)
J Biol Chem
, vol.258
, pp. 378-385
-
-
Quesney-Huneeus, V.1
Galick, H.A.2
Siperstein, M.D.3
Erickson, S.K.4
Spencer, T.A.5
Nelson, J.A.6
-
31
-
-
0031747545
-
Lovastatin induces apoptosis in malignant mesothelioma cells
-
Rubins JB, Greatens T, Kratzke RA, Tan AT, Polunovsky VA and Bitterman P (1998) Lovastatin induces apoptosis in malignant mesothelioma cells. Am J Resp Crit Care Med 157:1616-1622.
-
(1998)
Am J Resp Crit Care Med
, vol.157
, pp. 1616-1622
-
-
Rubins, J.B.1
Greatens, T.2
Kratzke, R.A.3
Tan, A.T.4
Polunovsky, V.A.5
Bitterman, P.6
-
32
-
-
0032489460
-
Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein
-
Sakai J, Nohturfft A, Goldstein JL and Brown MS (1998) Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. J Biol Chem 273:5785-5793.
-
(1998)
J Biol Chem
, vol.273
, pp. 5785-5793
-
-
Sakai, J.1
Nohturfft, A.2
Goldstein, J.L.3
Brown, M.S.4
-
33
-
-
0030669726
-
Differential activity of bcl-2 and ICE enzyme family protease inhibitors on Fas and puromycin-induced apoptosis of glioma cells
-
Schlapbach R and Fontana A (1997) Differential activity of bcl-2 and ICE enzyme family protease inhibitors on Fas and puromycin-induced apoptosis of glioma cells. Biochim Biophys Acta 1359:174-180.
-
(1997)
Biochim Biophys Acta
, vol.1359
, pp. 174-180
-
-
Schlapbach, R.1
Fontana, A.2
-
34
-
-
0030828019
-
Cooperative interception of neuronal apoptosis by BCL-2 and BAG-1 expression: Prevention of caspase activation and reduced production of reactive oxygen species
-
Schulz JB, Bremen D, Reed JC, Lommatzsch J, Takayama S, Wullner U, Loschmann PA, Klockgether T and Weller M (1997) Cooperative interception of neuronal apoptosis by BCL-2 and BAG-1 expression: Prevention of caspase activation and reduced production of reactive oxygen species. J Neurochem 69:2075-2086.
-
(1997)
J Neurochem
, vol.69
, pp. 2075-2086
-
-
Schulz, J.B.1
Bremen, D.2
Reed, J.C.3
Lommatzsch, J.4
Takayama, S.5
Wullner, U.6
Loschmann, P.A.7
Klockgether, T.8
Weller, M.9
-
35
-
-
0025202968
-
Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis
-
Sinensky M, Beck LA, Leonard S and Evans R (1990) Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis. J Biol Chem 265: 19937-19941.
-
(1990)
J Biol Chem
, vol.265
, pp. 19937-19941
-
-
Sinensky, M.1
Beck, L.A.2
Leonard, S.3
Evans, R.4
-
36
-
-
0028953585
-
Cholesterol, cholesterogenesis and cancer
-
Siperstein MD (1995) Cholesterol, cholesterogenesis and cancer. Adv Exp Med Biol 369:155-166.
-
(1995)
Adv Exp Med Biol
, vol.369
, pp. 155-166
-
-
Siperstein, M.D.1
-
37
-
-
0025719945
-
Inhibition of growth factor signaling pathways by lovastatin
-
Vincent TS, Wulfert E and Merler E (1991) Inhibition of growth factor signaling pathways by lovastatin. Biochem Biophys Res Commun 180:1284-1289.
-
(1991)
Biochem Biophys Res Commun
, vol.180
, pp. 1284-1289
-
-
Vincent, T.S.1
Wulfert, E.2
Merler, E.3
-
38
-
-
0017352864
-
Cholesterol biosynthesis and 3-hydroxy-3-methylglutaryl coenzyme A reductase in cultured glial and neuronal cells
-
Volpe JJ and Hennessy SW (1977) Cholesterol biosynthesis and 3-hydroxy-3-methylglutaryl coenzyme A reductase in cultured glial and neuronal cells. Biochim Biophys Acta 486:408-420.
-
(1977)
Biochim Biophys Acta
, vol.486
, pp. 408-420
-
-
Volpe, J.J.1
Hennessy, S.W.2
-
39
-
-
0030046472
-
Lovastatin inhibits the stimulation of mitogen-activated protein kinase by insulin in HIRcB fibroblasts
-
Xu XQ, McGuire TF, Blaskovich MA, Sebti SM and Romero G (1996) Lovastatin inhibits the stimulation of mitogen-activated protein kinase by insulin in HIRcB fibroblasts. Arch Biochem Biophys 326:233-237.
-
(1996)
Arch Biochem Biophys
, vol.326
, pp. 233-237
-
-
Xu, X.Q.1
McGuire, T.F.2
Blaskovich, M.A.3
Sebti, S.M.4
Romero, G.5
-
40
-
-
0029898894
-
Protein prenylation: Molecular mechanisms and functional consequences
-
Zhang FL and Casey PJ (1996) Protein prenylation: Molecular mechanisms and functional consequences. Annu Rev Biochem 65:241-269.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 241-269
-
-
Zhang, F.L.1
Casey, P.J.2
|