The isfA mutation specifically inhibits the SOS-dependent mutagenic pathway and does not selectively affect any particular base substitution

Mutagenesis

Volumn 14, Issue 3, 1999, Pages 295-300

  Felczak, Magdalena ^a   Bebenek, Anna ^a   Pietrzykowska, Irena ^a  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; ESCHERICHIA COLI; GENE MUTATION; MUTAGENESIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; ULTRAVIOLET IRRADIATION;

ESCHERICHIA COLI; LAC OPERON; MUTAGENESIS; POINT MUTATION; REC A RECOMBINASES; SOS RESPONSE (GENETICS); ULTRAVIOLET RAYS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0032891566     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/14.3.295     Document Type: Article

References (41)

1. Bebenek, A. and Pietrzykowska, I. (1995) A new mutation in Escherichia coli K12, isfA, which is responsible for inhibition of SOS functions. Mol. Gen. Genet., 248, 103-113.
2. Bebenek, A and. Pietrzykowska, I. (1996) The isfA mutation inhibits mutator activity and processing of UmuD protein in Escherichia coli recA730 strain. Mol. Gen. Genet., 250, 674-680.
3. Burckhardt, S.E., Woodgate, R., Scheuermann, R.H. and Echols, H. (1988) UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA. Proc. Natl Acad. Sci. USA, 85, 1811-1815.
4. Castellazzi, M., George, J. and Buttin, G. (1972) Prophage induction and cell division in E.coli. I. Further characterization of a thermosensitive mutation tif-I whose expression mimics the effects of UV irradiation. Mol. Gen. Genet., 119, 139-152.
5. Cupples, C.G. and Miller, J.H. (1989) A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions. Proc. Natl Acad. Sci. USA, 86, 5345-5349.
6. Echols, H. and Goodman, M.F. (1991) Fidelity mechanisms in DNA replication. Annu. Rev. Biochem., 60, 477-511.
7. Ennis, D.G., Fisher, B., Edmiston, S. and Mount, D.W. (1985) Dual role of Escherichia coli RecA protein in SOS mutagenesis. Proc. Natl Acad. Sci. USA, 82, 3325-3329.
8. Ennis, D.G., Levine, A.S., Koch, W.H. and Woodgate, R. (1995) Analysis of recA mutants with altered SOS functions. Mutat. Res., 336, 39-48.
9. Fijalkowska, I.J. and Schaaper, R.M. (1995) Effects of Escherichia coli dnaE antimutator alleles in a proofreading-deficient mutD5 strain. J. Bacteriol., 177, 5979-5986.
10. Fijalkowska, J.J., Dunn, R.L. and Schaaper, R.M. (1997) Genetic requirements and mutational specificity of the Escherichia coli SOS mutator activity. J. Bacteriol., 179, 7435-7445.
11. Friedberg, E.C, Walker, G.C. and Siede, W. (1995) DNA Repair and Mutagenesis. American Society for Microbiology Press, Washington, DC.
12. Kato, T., Ise, T. and Shinagawa, H. (1982) Mutational specificity of the umuC mediated mutagenesis in Escherichia coli. Biochimie, 64, 731-733.
13. Kim, S., Maenhaut-Michel, G., Yamada, M., Yamamoto, Y., Matsui, K., Sofuni, T. Nohmi, T. and Ohmori, H. (1997) Multiple pathways for SOS-induced mutagenesis in Escherichia coli: an overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA. Proc. Natl Acad. Sci. USA, 94, 13792-13797.
14. Lavery, P.E. and Kowalczykowski, S.C. (1992) Biochemical basis of the constitutive repressor cleavage activity of recA730 protein. A comparison to recA441 and recA803 proteins. J. Biol. Chem., 267, 20648-20658.
15. Little, J.W. (1991) Mechanism of specific LexA cleavage: autodigestion and the role of RecA coprotease. Biochimie, 73, 411-422.
16. Miller, J.H. (1972) Experiments in Molecular Genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
17. Miller, J.H. (1985) Mutagenic specificity of ultraviolet light. J. Mol. Biol., 182, 45-68.
18. Modrich, P. (1991) Mechanisms and biological effects of mismatch repair. Annu. Rev. Genet., 25, 229-253.
19. Modrich, P. and Lahue, R. (1996) Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu. Rev. Biochem., 65, 101-133.
20. Nohmi, T., Battista, J.R., Dodson, L.A. and Walker, G.C. (1988) RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and post-translational activation. Proc. Natl Acad. Sci. USA, 85, 967-978.
21. Rajagopolan, M., Lu, C., Woodgate, R., O'Donnell, M., Goodman, M.F.and Echols, H. (1992) Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proc. Natl Acad. Sci. USA, 89, 10777-10781.
22. Salles, B. and Defais, M. (1984) Signal of induction of recA protein in E.coli. Mutat Res., 131, 53-59.
23. Sanssafar, M. and Roberts, J.W. (1990) Nature of the SOS-inducing signal in Escherichia coli: the involvment of DNA replication. J. Mol. Biol, 212, 79-96.
24. Schaaper, R.M. and Dunn, R.L. (1987) Spectra of spontaneous mutations in Escherichia coli strains deffective in mismatch correction: the nature of in vivo DNA replication errors. Proc. Natl Acad. Sci. USA, 84, 6220-6224.
25. Schaaper, R.M., Danforth, B.N. and Glickman,B.W. (1985) Rapid repeated cloning of mutant lac repressor genes. Gene, 39, 181-189.
26. Schaaper, R.M., Dunn, R.L. and Glickman, B.W. (1987) Mechanisms of ultraviolet-induced mutation. Mutational spectra in the Escherichia coli lacI gene for a wild-type and an excision-repair-deficient strain. J. Mol. Biol., 198, 187-202.
27. Schendel, P.F.and Defais, M. (1980) The role of umuC gene product in mutagenesis by simple alkylating agents. Mol. Gen. Genet., 177, 661-665.
28. Sedgwick, S.G, and Goodwin, P.A. (1985) Difference in mutagenic and recombinational DNA repair in enterobacteria. Proc. Natl Acad. Sci. USA, 82, 4172-4176.
29. Shinagawa, H., Iwasaki, H., Kato, T. and Nakata, A. (1988) RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis. Proc. Natl Acad. Sci. USA, 85, 1806-1810.
30. Slater, S.C. and Maurer, R. (1991) Requirements for bypass of UV-induced lesions in single-stranded DNA of bacteriophage øX174 in Salmonella typhimurium. Proc. Natl Acad. Sci. USA, 88, 1251-1255.
31. Sweasy, J.B., Witkin, E.M., Sinha, N. and Roegner-Maniscalco, V. (1990) RecA protein of Escherichia coli has a third essential role in SOS mutator activity. J. Bacteriol., 172, 3030-3036.
32. Todd, P.A., Brouwer, J. and Glickman, B.W. (1981) Influence of DNA repair deficiences on MMS- and EMS-induced mutagenesis in Escherichia coli K12. Mutat. Res., 82, 239-250.
33. Vogel, H.L. and Bonner, D.M. (1956) Acetylomithinase of Escherichia coli: partial purification and some properties. J. Biol. Chem., 218, 97-106.
34. Wang, W.B. and Tessman, E.S. (1986) Location of functional regions of the Escherichia coli RecA protein by DNA sequence analysis of RecA protease-constitutive mutants. J. Bacteriol., 168, 901-910.
35. Watanabe, M., Nohmi, T.and Ohta, T. (1994) Effects of the umuDC, mucAB and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: I. Frameshift mutagenesis. Mutat. Res., 314, 27-37.
36. Watanabe-Akanuma, M., Woodgate, R and Ohta, T. (1997) Enhanced generation of A:T→T:A transversions in recA730lexA(Def) mutant of Escherichia coli. Mutat. Res., 373, 61-66.
37. Witkin, E.M. and Kogoma, T. (1984) Involvment of the activated form of RecA protein in SOS mutagenesis and stable DNA replication in Escherichia coli. Proc. Natl Acad. Sci. USA, 81, 7539-7543.
38. Witkin, E.M., McCall, J.O., Volkert, M.R. and Wermundsen, J.E. (1982) Constitutive expression of SOS functions and modulation of mutagenesis resulting from resolution of genetic instability at or near the recA locus of Escherichia coli. Mol. Gen. Genet., 185, 43-50.
39. Woodgate, R. and Ennis, D.G. (1991) Levels of chromosomally encoded Umu proteins and requirements for in vivo UmuD cleavage. Mol. Gen. Genet., 229, 10-16.
40. Woodgate, R. and Levine, A.S. (1996) Damage inducible mutagenesis: recent insights into the activities of the Umu family of mutagenesis proteins. Cancer Surv., 28, 117-140.
41. Woodgate, R., Rajagopolan, M., Lu, C. and Echols, H. (1989) UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD′. Proc. Natl Acad. Sci. USA, 86, 7301-7305.