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Volumn 14, Issue 4, 1999, Pages 903-909

Pharmacokinetics of morphine and its glucuronides following intravenous administration of morphine in patients undergoing continuous ambulatory peritoneal dialysis

Author keywords

Morphine; Morphine glucuronides; Peritoneal dialysis; Pharmacokinetics; Renal failure

Indexed keywords

DRUG METABOLITE; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE;

EID: 0032890987     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/14.4.903     Document Type: Article
Times cited : (49)

References (18)
  • 1
    • 0029738663 scopus 로고    scopus 로고
    • The disposition of morphine and its 3-and 6-glucuronide metabolites in human and animals, and the importance of the metabolites to the pharmacological effects of morphine
    • Milne RW, Nation RL, Somogyi AA. The disposition of morphine and its 3-and 6-glucuronide metabolites in human and animals, and the importance of the metabolites to the pharmacological effects of morphine Drug Metab Rev 1996; 28: 345-472
    • (1996) Drug Metab Rev , vol.28 , pp. 345-472
    • Milne, R.W.1    Nation, R.L.2    Somogyi, A.A.3
  • 2
    • 0025190756 scopus 로고
    • Morphine and metabolite behavior after different routes of morphine administration. Demonstration of the importance of the active metaolite morphine-6-glucuronide
    • Osborne RJ, Joel S, Trew D, Slevin M. Morphine and metabolite behavior after different routes of morphine administration. Demonstration of the importance of the active metaolite morphine-6-glucuronide. Clin Pharmacol Ther 1990; 47: 12-19
    • (1990) Clin Pharmacol Ther , vol.47 , pp. 12-19
    • Osborne, R.J.1    Joel, S.2    Trew, D.3    Slevin, M.4
  • 4
    • 0023191568 scopus 로고
    • Kinetics of morphine in patients with renal failure
    • Sawe J, Odar-Cederlof I. Kinetics of morphine in patients with renal failure. Eur J Clin Pharmacol 1987; 32: 377-821
    • (1987) Eur J Clin Pharmacol , vol.32 , pp. 377-821
    • Sawe, J.1    Odar-Cederlof, I.2
  • 5
    • 0022532772 scopus 로고
    • Morphine intoxication in renal failure. The role of morphine-6-glucuronide
    • Osborne RJ, Simon PJ, Slevin ML. Morphine intoxication in renal failure. The role of morphine-6-glucuronide. Br Med J 1986; 292; 1548-1549
    • (1986) Br Med J , vol.292 , pp. 1548-1549
    • Osborne, R.J.1    Simon, P.J.2    Slevin, M.L.3
  • 6
    • 0030879284 scopus 로고    scopus 로고
    • Plasma morphine and glucuronide (M3G and M6G) concentrations in hospice inpatients
    • Ashby M, Fleming B, Wood M, Somogyi A. Plasma morphine and glucuronide (M3G and M6G) concentrations in hospice inpatients. J Pain Sympt Manag 1997; 14: 157-167
    • (1997) J Pain Sympt Manag , vol.14 , pp. 157-167
    • Ashby, M.1    Fleming, B.2    Wood, M.3    Somogyi, A.4
  • 7
    • 0015116683 scopus 로고
    • Analgesic effect of morphine glucuronides
    • Shimomura K, Kamata O, Ueki S et al. Analgesic effect of morphine glucuronides. Tohoku J Exp Med 1971; 105: 45-52
    • (1971) Tohoku J Exp Med , vol.105 , pp. 45-52
    • Shimomura, K.1    Kamata, O.2    Ueki, S.3
  • 8
    • 0024369341 scopus 로고
    • Pharmacological characterization of morphine-6-beta-glucuronide, a very potent morphine metabolite
    • Paul D, Standifer KM, Inturrissi CE et al. Pharmacological characterization of morphine-6-beta-glucuronide, a very potent morphine metabolite. J Pharmacol Exp Ther 1989; 251: 477-483
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 477-483
    • Paul, D.1    Standifer, K.M.2    Inturrissi, C.E.3
  • 9
    • 0028885284 scopus 로고
    • Simultaneous determination of dihydrocodeine and dihyhydromorphine in serum by gas chromatography-tandem mass spectrometry
    • Hofmann U, Fromm MF, Johnson S et al. Simultaneous determination of dihydrocodeine and dihyhydromorphine in serum by gas chromatography-tandem mass spectrometry. J Chromatogr B 1995; 663: 59-65
    • (1995) J Chromatogr B , vol.663 , pp. 59-65
    • Hofmann, U.1    Fromm, M.F.2    Johnson, S.3
  • 10
    • 0029966451 scopus 로고    scopus 로고
    • Determination of morphine, morphine-3-glucuronide and morphine-6-glucuronide in human serum by solid-phase extraction and liquid chromatography-mass spectromety with electrospray ionisation
    • Tyrefors N, Hyllbrant B, Ekman L et al. Determination of morphine, morphine-3-glucuronide and morphine-6-glucuronide in human serum by solid-phase extraction and liquid chromatography-mass spectromety with electrospray ionisation. J Chromatogr A 1996; 729: 279-285
    • (1996) J Chromatogr A , vol.729 , pp. 279-285
    • Tyrefors, N.1    Hyllbrant, B.2    Ekman, L.3
  • 11
    • 0031933116 scopus 로고    scopus 로고
    • Systematic review of factors affecting ratios of morphine and its major metabolites
    • Faura CC, Collins SL, Moore RA, McQuay HJ. Systematic review of factors affecting ratios of morphine and its major metabolites. Pain 1998; 74: 43-53
    • (1998) Pain , vol.74 , pp. 43-53
    • Faura, C.C.1    Collins, S.L.2    Moore, R.A.3    McQuay, H.J.4
  • 12
    • 0024369341 scopus 로고
    • Pharmacological characterization of morphine-6-beta-glucuronide, a very potent morphine metabolite
    • Paul D, Standifer KM, Inturrisi CE et al. Pharmacological characterization of morphine-6-beta-glucuronide, a very potent morphine metabolite. J Pharmacol Exp Ther 1989; 25: 477-483
    • (1989) J Pharmacol Exp Ther , vol.25 , pp. 477-483
    • Paul, D.1    Standifer, K.M.2    Inturrisi, C.E.3
  • 13
    • 0025219273 scopus 로고
    • Efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: Comparison with morphine
    • Hanna MH, Peat SJ, Woodham M et al. Efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: comparison with morphine. Br J Anaesth 1990; 64: 547-550
    • (1990) Br J Anaesth , vol.64 , pp. 547-550
    • Hanna, M.H.1    Peat, S.J.2    Woodham, M.3
  • 14
    • 0029786352 scopus 로고    scopus 로고
    • Evidence for P-glycoprotein modulated penetration of morphine-6-glucuronide into brain capillary endothelium
    • Huwyler J, Drewe J, Klusemann et al. Evidence for P-glycoprotein modulated penetration of morphine-6-glucuronide into brain capillary endothelium. Br J Parmacol 1996; 118: 1879-1885
    • (1996) Br J Parmacol , vol.118 , pp. 1879-1885
    • Huwyler, J.1    Drewe, J.2
  • 15
    • 0025997427 scopus 로고
    • Circumvention of multidrug resistance mediated by P-170 glycoprotein using calcium anatgonists in primary human renal cell carcinoma
    • Mickisch GH, Kossig J, Tschada R et al. Circumvention of multidrug resistance mediated by P-170 glycoprotein using calcium anatgonists in primary human renal cell carcinoma. Urol Int 1991; 47: 118-125
    • (1991) Urol Int , vol.47 , pp. 118-125
    • Mickisch, G.H.1    Kossig, J.2    Tschada, R.3
  • 16
    • 0028825399 scopus 로고
    • Absence of the mdrla P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin and cyclosporine A
    • Schinkel AH, Wagenaar E, van Deetmer L et al. Absence of the mdrla P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin and cyclosporine A. J Clin Invest 1995; 96: 1698-1705
    • (1995) J Clin Invest , vol.96 , pp. 1698-1705
    • Schinkel, A.H.1    Wagenaar, E.2    Van Deetmer, L.3
  • 17
    • 0029979669 scopus 로고    scopus 로고
    • Reversal of multidrug resistance by amitriptyline in vitro
    • Varga A, Nugel H, Bachr R et al. Reversal of multidrug resistance by amitriptyline in vitro. Anticancer Res 1996; 16: 209-211
    • (1996) Anticancer Res , vol.16 , pp. 209-211
    • Varga, A.1    Nugel, H.2    Bachr, R.3
  • 18
    • 0345368078 scopus 로고    scopus 로고
    • Lack of analgesic activity of morphine-6-glucuronide after short-term intravenous administration in healthy volunteers
    • Lötsch J, Kobal G, Stockmann A et al. Lack of analgesic activity of morphine-6-glucuronide after short-term intravenous administration in healthy volunteers. Anesthesiology 1997; 87: 1348-1358
    • (1997) Anesthesiology , vol.87 , pp. 1348-1358
    • Lötsch, J.1    Kobal, G.2    Stockmann, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.