Insulin activates caspase-3 by a phosphatidylinositol 3'-kinase-dependent pathway

Cellular Signalling

Volumn 11, Issue 1, 1999, Pages 15-23

  Godbout, Jonathan P ^a   Cengel, Keith A ^a   Cheng, Shu Ling ^a   Minshall, Christian ^a   Kelley, Keith W ^a   Freund, Gregory G ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Apoptosis; c Jun N terminal kinase; Caspase 3; Insulin; Phosphatidylinositol 3' kinase; Signal transduction

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; INSULIN; PHOSPHATIDYLINOSITOL KINASE; PHOSPHOTRANSFERASE; PROTEINASE; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CELL CYCLE; CELL DEATH; CELL LINE; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MYELOMA CELL; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CASPASE 3; CASPASES; ENZYME ACTIVATION; HUMANS; INSULIN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0032889694     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0898-6568(98)00024-2     Document Type: Article

References (48)

1. Yuan J., Shaham S., Ledoux S., Ellis M., Horvitz H.R. Cell. 75:1993;641-652.
2. Cohen G.M. Biochem. J. 326:1997;1-16.
3. Alnemri S.E. J. Cell Biochem. 64:1997;33-42.
4. Kothakota S., Azuma A., Reinhard C., Klippel A., Tang J., Chu K., McGarry T.J., Kirschner M.W., Koths K., Kwiatkowski J., Williams L.T. Science. 278:1997;294-297.
5. Kuida K., Zeng T.S., Na S., Kuan C., Karasuyama H., Rakic P., Flavell R.A. Nature. 384:1996;368-372.
6. Nicholson D.W., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., Lazebnik Y.A., Munday N.A., Raju S.M., Smulson M.E., Yamin T.-T., Yu V.L., Miller D.K. Nature. 376:1995;37-43.
7. Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., Earnshaw W.C. Nature. 371:1994;346-347.
8. Han Z., Malik N., Carter T., Reeves W.H., Wyche J.H., Hendrickson E.A. J. Biol. Chem. 271:1996;25035-25040.
9. Seimiya H., Mashima T., Toho M., Tsuro T. J. Biol. Chem. 272:1997;4631-4636.
10. Kyriakis J.M., Avruch J. J. Biol. Chem. 271:1996;24313-24316.
11. Coso O.A., Chiariello M., Yu J.-C., Teramoto H., Crespo P., Xu N., Miki T., Gutkind J.S. Cell. 81:1995;1137-1146.
12. Minden A., Lin A., Claret F.-X., Abo A., Karin M. Cell. 81:1995;1147-1157.
13. Rosette C., Karin M. Science. 274:1996;1194-1197.
14. Hirai S., Katoh M., Terada M., Kyriakis J.M., Zon L.I., Rana A., Avurch J., Ohno S. J. Biol. Chem. 272:1997;15167-15173.
15. Derijard B., Hibi M., Wu H.I., Barrett T., Su B., Deng T., Karin M., Davis R.J. Cell. 76:1994;1025-1037.
16. Hibi M., Lin A., Smeal T., Minden A., Karin M. Genes Dev. 11:1993;2135-2148.
17. Angel P., Hattori K., Smeal T., Karin M. Cell. 55:1988;875-885.
18. Xia Z., Dickens M., Raingeaud J., Davis R.J., Greenberg M.E. Science. 270:1995;1326-1331.
19. Stellar H. Science. 267:1995;1445-1448.
20. Allen P.D., Bustin S.A., Newland A.C. Blood Rev. 7:1993;63-73.
21. Stefanis L., Park D.S., Yan C.Y., Farinelli S.E., Troy C.M., Shelanski M.L., Greene L.A. J. Biol. Chem. 271:1996;30663-30670.
22. Ohta T., Kinoshita T., Naito M., Nazaki T., Masutani M., Tsuruo T., Miyajima A. J. Biol. Chem. 272:1997;23111-23116.
23. Kim H.-C., Upadhay S., Li G., Palmer K.C., Deul T.F. Proc. Natl. Acad. Sci. USA. 92:1995;9500-9504.
24. Yang B.-H., Chang H.-M., Wang Y.-S., Chen R.-F., Lin S.-J. Biochim. Biophys. Acta. 1314:1996;83-92.
25. Xu Y., Nguyen Q., Lo D.C., Czaja M. J. Cell. Physiol. 170:1997;192-199.
26. Kapeller R., Cantely L.C. Bioessays. 16:1994;565-576.
27. Yano Y., Nakanishi S., Kimura K., Hanai N., Saitoh Y., Fukui Y., Nonomura Y., Matsuda Y. J. Biol. Chem. 268:1993;25846-25856.
28. Vlahos C.J., Matter W.F., Hui K.Y., Brown R.F. J. Biol. Chem. 269:1994;5241-5248.
29. Miller B.S., Shankavaram U.T., Horney M.J., Gore A.C., Kurtz D.T., Rosenzweig S.A. Biochemistry. 35:1996;8769-8775.
30. Lopez-Ilasaca M., Li W., Uren A., Yu J.-C., Kazlauskas A., Gutkind J.S., Heidaran M.A. Biochem. Biophys. Res. Com. 232:1997;273-277.
31. Freund G.G., Kulas D.T., Way B.A., Mooney R.A. Cancer Res. 54:1994;3179-3185.
32. Shimizu S., Eguchi Y., Kamiike W., Matsuda H., Tsujimoto Y. Oncogene. 12:1996;2251-2257.
33. Walker N.P., Talanian R.V., Brady K.D., Dang L.C., Bump N.J., Ferenz C.R., Franklin S., Ghayur T., Hackett M.C., Hammill L.D., Herzog L., Huguni M., Houy W., Mankovich J.A., McGuiness Orlewicz E., Paskind M., Pratt A., Reis P., Summani A., Terranova M., Welch J.P., Xiong L., Moller A., Tracey D.E., Kamen R., Wong W.W. Cell. 78:1994;343-352.
34. Freund G.G., Kulas D.T., Mooney R.A. J. Immunol. 151:1993;1811-1820.
35. Hockenbery D., Nunez G., Milliman C., Schreiber R.D., Korsmeyer S.J. Nature. 348:1990;334-336.
36. Belloc F., Dumain P., Boisseau M.R., Jalloustre C., Reiffers J., Bernard P., Lacombe F. Cytometry. 17:1994;59-65.
37. Minshall C., Arkins S., Freund G.G., Kelley K.W. J. Immunol. 156:1996;939-947.
38. Krishan A. J. Cell Biol. 66:1975;188-193.
39. Duckworth B.C., Cantley L.C. J. Biol. Chem. 272:1997;27665-27670.
40. Park D.S., Stefanis L., Yan C.Y., Farinelli S.E., Greene L.A. J. Biol. Chem. 271:1996;21898-21905.
41. Hartwell L.H., Kastan M.B. Science. 266:1994;1821-1827.
42. Elledge S. Science. 274:1996;1664-1671.
43. Stillman B. Science. 274:1996;1659-1663.
44. Sherr C.J. Science. 274:1996;1672-1677.
45. Koontz J.W., Iwashashi M. Science. 211:1981;947-949.
46. Cobb M.H., Goldsmith E.J. J. Biol. Chem. 270:1995;14843-14846.
47. Deacon K., Blank J.L. J. Biol. Chem. 272:1997;14489-14496.
48. Chaung T.H., Hahn K.M., Lee J.D., Danley D.E., Bokoch G.M. Mol. Biol. 8:1997;1687-1698.