The effect of curcumin on glutathione-linked enzymes in K562 human leukemia cells

Toxicology Letters

Volumn 109, Issue 1-2, 1999, Pages 87-95

  Singhal, Sharad S ^a,b   Awasthi, Sanjay ^a,b   Pandya, Utpal ^a   Piper, John T ^a   Saini, Manjit K ^a   Cheng, Ji Zhong ^a   Awasthi, Yogesh C ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS AT ARLINGTON   (United States)

Author keywords

4 Hydroxynonenal; Curcumin; Glutathione peroxidase; Glutathione S transferases; K562 cell line

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 4 HYDROXYNONENAL; CURCUMIN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE REDUCTASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CANCER PREVENTION; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DETOXIFICATION; DRUG MECHANISM; ENZYME BINDING; ENZYME REGULATION; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIPID PEROXIDATION; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; CURCUMIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HUMANS; INDICATORS AND REAGENTS; ISOENZYMES; K562 CELLS; LEUKEMIA; LIPID PEROXIDATION; PRECIPITIN TESTS; SELENIUM;

ANIMALIA; CURCUMA LONGA;

EID: 0032888530     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00124-1     Document Type: Article

References (53)

1. Alin P., Danielson U.H., Mannervik B. 4-Hydroxyalk-2-enals are substrates for glutathione S-transferase. FEBS Lett. 179:1985;267-270.
2. Ames B.N., Shigenaga M.K., Hagen T.M. Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. U.S.A. 90:1993;7915-7922.
3. Awasthi Y.C., Beutler E., Srivastava S.K. Purification and properties of human erythrocyte glutathione peroxidase. J. Biol. Chem. 250:1975;5144-5149.
4. Awasthi Y.C., Dao D.D., Saneto R.P. Interrelationship between anionic and cationic forms of glutathione S-transferases of human liver. Biochem. J. 191:1980;1-10.
5. Awasthi Y.C., Partridge C.A., Theodore C., Dao D.D. Comparative effect on the induction of the subunits of rat liver glutathione S-transferases by butylated hydroxytoluene. Comp. Biochem. Physiol. 78C:1984;39-41.
6. Awasthi Y.C., Singhal S.S., Awasthi S. Mechanisms of anti-carcinogenic effects of antioxidant nutrients. Watson R.R. Nutrition and Cancer. 1995;139-172 CRC Press, Boca Raton, FL.
7. Awasthi S., Srivatava S.K., Piper J.T., Singhal S.S., Chaubey M., Awasthi Y.C. Curcumin protects against 4-hydroxy-2-trans-nonenal-induced cataract formation in rat lenses. Am. J. Clin. Nutr. 64:1996;761-766.
8. Barrera, G., Di Mauro, C., Muraca, R., Ferrero, D., Cavalli, G., Fazio, V.M., Paradisi, Dianzani, M.U., 1991. Induction of differentiation in human HL-60 cells by 4-hydroxynonenal, a product of lipid peroxidation, Exp. Cell Res. 197(2), 148-152.
9. Benson A.M., Batzinger R.P., Ou S.Y., Bueding E., Cha Y.N., Talalay P. Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo(a)pyrene by dietary antioxidants. Cancer Res. 38:1978;4486-4495.
10. Beutler E., Duron O., Kelley B.M. Improved method for the determination of blood glutathione. J. Lab. Clin. Med. 61:1963;882-888.
11. Beutler E. Beutler E. Red Cell Metabolism: A Manual Of Biochemical Methods. 1984;68-73 Grune and Stratton, Orlando, FL.
12. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein -dye binding. Anal. Biochem. 72:1976;248-254.
13. Dianzani M.U. 4-Hydroxynonenal and cell signalling. Free Rad. Res. 28(6):1998;553-560.
14. Esterbauer H., Schaur R.J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Rad. Biol. Med. 11:1991;81-128.
15. Fazio V.M., Rinaldi M., Ciafre S., Barrera G., Farace M.G. Control of neoplastic cell proliferation and differentiation by restoration of 4-hydroxynonenal physiological concentrations. Mol. Aspects Med. 14(3):1993;217-228. [Review] [43 references].
16. Grune T., Siems W.G., Petras T. Identification of metabolic pathways of the lipid peroxidation product 4-hydroxynonenal in in situ perfused rat kidney. J. Lip. Res. 38(8):1997;1660-1665.
17. Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249:1974;7130-7139.
18. He N.G., Singhal S.S., Srivastava S.K., Zimniak P., Awasthi Y.C., Awasthi S. Transfection of a 4-hydroxynonenal metabolizing glutathione s-transferase isozyme, mouse GSTA4-4, confers doxorubicin resistance to chinese hamster ovary cells. Arch. Biochem. Biophys. 333:1996;214-220.
19. Kakar S.S., Roy D. Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin. Cancer Lett. 87:1994;85-89.
20. Kruman I., Bruce-Keller A.J., Bredesen D., Waeg G., Mattson M.P. Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J. Neurosci. 17:1997;5089-5100.
21. Kunchandy E., Rao M.N. Oxygen radical scavenging activity of curcumin. Int. J. Pharm. 58:1990;237-240.
22. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
23. Liu J.Y., Lin S.J., Lin J.K. Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells. Carcinogenesis. 14:1993;857-861.
24. Mukhopadhyay A., Basu N., Ghatak N., Gujral P.K. Anti-inflammatory and irritant activities of curcumin analogues in rats. Agents Actions. 12:1982;508-515.
25. Mulky N., Amonkar A.J., Bhide S.V. Antimutagenicity of curcumins and related compound: the structural requirements for the antimutagenicity of curcumins. Indian Drugs. 25:1987;91-95.
26. Nagabhushan M., Bhide S.V. Curcumin as an inhibitor of cancer. J. Am. Coll. Nutr. 11:1992;192-198.
27. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95:1979;351-358.
28. Piper J.T., Singhal S.S., Salameh M.S., Torman R.T., Awasthi Y.C., Awasthi S. Mechanisms of anticarcinogenic properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver. Int. J. Biochem. Cell Biol. 30:1998;445-456.
29. Racke F.K., Lewandowska K., Goueli S., Goldfarb A.N. Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells. J. Biol. Chem. 272:1997;23366-23370.
30. Rao T.S., Basu N., Siddiqui H.H. Anti-inflammatory activity of curcumin analogues. Ind. J. Med. Res. 75:1982;574-578.
31. Rao C.V., Simi B., Reddy B.S. Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon. Carcinogenesis. 14:1993;2219-2225.
32. Rao C.V., Rivenson A., Simi B., Reddy B.S. Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res. 55:1995;259-266.
33. Reddy A.C., Lokesh B.R. Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygen species and the oxidation of ferrous iron. Mol. Cell. Biochem. 137:1994;1-8.
34. Seelig G.F., Meister A. Gamma-glutamylcysteine synthetase. Interactions of an essential sulfhydryl group. J. Biol. Chem. 259:1984;3534-3538.
35. Sharma O.P. Antioxidant activity of curcumin and related compounds. Biochem. Pharmacol. 25:1976;1811-1812.
36. Sharma R., Ahmad H., Singhal S.S., Saxena M., Srivastava S.K., Awasthi Y.C. Comparative studies on the effect of butylated hydroxyanisole on glutathione and glutathione S-transferases in the tissues of male and female CD-1 mice. Comp. Biochem. Physiol. 105C:1993;31-37.
37. Singh S.V., Haque A.K., Ahmad H., Medh R.D., Awasthi Y.C. Glutathione S-transferase isoenzymes in human lung tumors. Carcinogenesis. 9:1988;1681-1685.
38. Singhal S.S., Saxena M., Ahmad H., Awasthi S., Haque A.K., Awasthi Y.C. Glutathione S-transferases of human lung: characterization and evaluation of the protective role of the alpha-class isozymes against lipid peroxidation. Arch. Biochem. Biophys. 299:1992;232-241.
39. Singhal S.S., Zimniak P., Awasthi S., Piper J.T., He N.G., Teng J.I., Petersen D.R., Awasthi Y.C. Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues. Arch. Biochem. Biophys. 311:1994;242-250.
40. Singhal S.S., Piper J.T., Awasthi S., Zimniak P., Awasthi Y.C. Polyclonal antibodies specific to human glutathione S-transferase 5.8 (hGST 5.8). Biochem. Arch. 11:1995;189-195.
41. Soudamini K.K., Kuttan R. Inhibition of chemical carcinogenesis by curcumin. J. Ethnopharmacol. 27:1989;227-233.
42. Srimal R.C., Dhawan B.N. Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J. Pharm. Pharmacol. 25:1973;447-452.
43. Srivastava R., Srimal R.C. Modification of certain inflammation-induced biochemical changes by curcumin. Ind. J. Med. Res. 81:1985;215-223.
44. Srivastava S., Chandra A., Wang L.F., Seifert W.E.J., DaGue B.B., Ansari N.H., Srivastava S.K., Bhatnagar A. Metabolism of the lipid peroxidation product, 4-hydroxy-trans-2-nonenal, in isolated perfused rat heart. J. Biol. Chem. 273(18):1998;10893-10900.
45. Sugiyama Y., Kawakishi S., Osawa T. Involvement of the beta-diketone moiety in the antioxidative mechanism of tetrahydrocurcumin. Biochem. Pharmacol. 52:1996;519-525.
46. Susan M., Rao M.N. Induction of glutathione S-transferase activity by curcumin in mice. Arzneimittel-Forschung. 42:1992;962-964.
47. Talalay P. Mechanisms of induction of enzymes that protect against chemical carcinogenesis. Adv. Enzyme Regul. 28:1989;237-250.
48. Thompson K.M., Haibach H., Sunde R.A. Growth and plasma triiodothyronine concentrations are modified by selenium deficiency and repletion in second generation selenium-deficient rats. J. Nutr. 125:1995;864-873.
49. Tonnesen H.H., Greenhill J.V. Studies on curcumin and curcuminoids. XXII: Curcumin as a reducing agent and as a radical scanvager. Int. J. Pharm. 87:1992;79-87.
50. Tonnesen H.H., Karlsen J., van Henegouwen G.B. Studies on curcumin and curcuminoids. VIII. Photochemical stability of curcumin. Z. Lebensm. Unters. Forsch. 183:1986;116-122.
51. Towbin H., Staehelin T., Gordo J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 76:1979;4350-4354.
52. Wattenberg L.W. Chemoprevention of cancer. Cancer Res. 45:1985;1-8.
53. Zimniak P., Singhal S.S., Srivastava S.K., Awasthi S., Sharma R., . Hayden J.B., Awasthi Y.C. Estimation of genomic complexity, heterologous expression, and enzymatic characterization of mouse glutathione S-transferase mGSTA4-4 (GST 5.7). J. Biol. Chem. 269:1994;992-1000.