Comparative gene transfer efficiency of low molecular weight polylysine DNA-condensing peptides

Journal of Peptide Research

Volumn 54, Issue 4, 1999, Pages 311-318

  McKenzie, D L ^a   Collard, W T ^a   Rice, Kevin G ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

DNA condensate; Gene delivery; Gene therapy; Polylysine

Indexed keywords

CYSTEINE PROTEINASE; PLASMID DNA; POLYLYSINE;

AMINO ACID SEQUENCE; ARTICLE; CHROMATOGRAPHY; DNA DETERMINATION; GENE EXPRESSION; GENE TRANSFER; MASS SPECTROMETRY; MOLECULAR WEIGHT; PRIORITY JOURNAL;

CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; DNA; GENE TRANSFER TECHNIQUES; HUMANS; LUCIFERASES; MASS SPECTROMETRY; MOLECULAR WEIGHT; PARTICLE SIZE; POLYLYSINE; SPECTROMETRY, FLUORESCENCE;

EID: 0032887067     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.1999.00104.x     Document Type: Article

References (28)

1. 1. Ledley, F.D. (1995) Nonviral gene therapy: The promise of genes as pharmaceutical products. Hum. Gene Ther. 6, 1129-1144.
2. 2. Tang, M.X., Redemann, C.T. & Szoka, F.C. Jr (1996) In vitro gene delivery by degraded polyamidoamine dendrimers. Bioconjugate Chem. 7, 703-714.
3. 3. Haensler, J. & Szoka, F.C. Jr (1993) Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjugate Chem. 4, 372-379.
4. 4. Boussif, O., Zanta, M.A. & Behr, J.-P. (1996) Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold. Gene Ther. 3, 1074-1080.
5. 5. Murphy, J.E., Uno, T., Hamer, J.D., Cohen, F.E., Dwarki, V. & Zuckermann, R.N. (1998) A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery. Proc. Natl Acad. Sci. USA 95, 1517-1522.
6. 6. Niidome, T., Ohmori, N., Ichinose, A., Wada, A., Mihara, H., Toshiya, H. & Haruhiko, A. (1997) Binding of cationic α-helical peptides to plasmid DNA and their gene transfer abilities into cells. J. Biol. Chem. 272, 15307-15312.
7. 7. Morris, M.C., Vidal, P., Chaloin, L., Heitz, F. & Divita, G. (1997) A new peptide vector for efficient delivery of oligonucleotides into mammalian cells. Nucleic Acids Res. 25, 2730-2736.
8. 8. Erbacher, P., Roche, A.C., Monsigny, M. & Midoux, P. (1995) Glycosylated polylysine/ DNA complexes: gene transfer efficiency in relation with the size and the sugar substitution level of glycosylated polylysines and with the plasmid size. Bioconjugate Chem. 6, 401-410.
9. 9. Wolfert, M.A. & Seymour, L.W. (1996) Atomic force microscopic analysis of the influence of the molecular weight of poly (L) lysine on the size of polyelectrolyte complexes formed with DNA. Gene Ther. 3, 269-273.
10. 10. Tang, M.X. & Szoka, F.C. Jr (1997) The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther. 4, 823-832.
11. 11. Wu, G.Y. & Wu, C.Y. (1988) Receptor-mediated gene delivery and expression in vivo. J. Biol. Chem. 29, 14621-14624.
12. 12. Midoux, P., Mendes, C., Legrand, A., Raimond, J., Mayer, R., Monsigny, M. & Roche, C. (1993) Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells. Nucleic Acids Res. 21, 871-878.
13. 13. Merwin, J.R., Noell, G.S., Thomas, W.L., Chiou, H.C., DeRome, M.E., McKee, T.D., Spitalny, G.L. & Findeis, M.A. (1994) Targeted delivery of DNA using YEE (GalNAcAH) 3, a synthetic glycopeptide ligand for the asialoglycoprotein receptor. Bioconjugate Chem. 5, 612-620.
14. 14. Katayose, S. & Kataoka, K. (1997) Water-soluble polyion complex associates of DNA and poly (ethylene glycol)-poly (L-lysine). Block Copolymers 8, 702-707.
15. 15. Toncheva, V., Wolfert, M.A., Dash, P.R., Oupicky, D., Ulbrich, K., Seymour, L.W. & Schacht, E.H. (1998) Novel vectors for gene delivery formed by self-assembly of DNA with poly (L-) lysine grafted with hydrophilic polymers. Biochim. Biophys. Acta 1380, 354-368.
16. 16. McKee, T.D., DeRome, M.E., Wu, G.Y. & Findeis, M.A, (1994) Preparation of asialoorosomucoid polylysine conjugates. Bioconjugate Chem. 5, 306-311.
17. 17. Wadhwa, M.S., Collard, W.T., Adami, R.C., McKenzie, D.L. & Rice, K.G. (1997) Peptide mediated gene delivery: influence of peptide structure on gene expression. Bioconjugate Chem. 8, 81-88.
18. 18. Harding, M.M. (1992) NMR studies on YSPTSPSY: implications for the design of DNA bisintercalators. J. Med. Chem. 35, 4658-4664.
19. 19. Reich, Z., Ittah, Y., Weinberger, S. & Minsky, A. (1990) Chiral and structural discrimination in binding of polypeptides with condensed nucleic acid structures. J. Biol. Chem. 10, 5590-5594.
20. 20. Wehling, K., Arfmann, H.A., Selpke, G. & Wagner, K.G. (1977) Specificity of DNA basic polypeptide interactions. II. Influence of aromatic amino acid residues investigated with agarose bound lysine copolypeptides. Nucleic Acids Res. 4, 513-522.
21. 21. Plank, C., Zatloukal, K., Cotten, M., Mechtler, K. & Wagner, E. (1992) Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA completed with an artificial tetraantennary galactose ligand. Bioconjugate Chem. 3, 533-539.
22. 22. Ball, H.L. & Mascagni, P. (1992) Purification of synthetic peptides using reversible Chromatographic probes based on the Fmoc molecule. Int. J. Peptide Protein Res. 40, 370-379.
23. 23. Weigele, M., DeBernardo, S.L., TneGi, J.P. & LeimGruger, W. (1972) A novel reagent for the fluorometric assay of primary amines. J. Am. Chem. Soc. 94, 5927-5928.
24. 24. Wadhwa, M., Knoell, D.L., Young, A.P. & Rice, K.G. (1995) Targeted gene delivery with a low molecular weight glycopeptide. Bioconjugate Chem. 6, 283-291.
25. 25. Pouton, C.W. & Seymour, L.W. (1998) Key issues in non-viral gene delivery. Adv. Drug Deliv. Rev. 34, 3-19.
26. 26. Brasier, A.R., Tate, J.E. & Harener, J.F. (1989) Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines. BioTechniques 7, 1116-1122.
27. 27. Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analyt. Biochem. 72, 248-254.
28. 28. Adami, R.C., Collard, W.T., Gupta, S.A., Kwok, K.Y., Bonadio, S. & Rice, K.G. (1998) Stability of peptide condensed plasmid DNA formulations. J. Pharmac. Sci. 87, 678-683.