Effect of dietary lipids on hepatic Na+,K+-ATPase in cyclosporine A- treated rats: Immunocytochemical analysis of α1 subunit by confocal laser scanning microscopy imaging

Digestive Diseases and Sciences

Volumn 44, Issue 8, 1999, Pages 1643-1649

  Benkoël, Liliane ^a,b   Chanussot, Françoise ^a,b   Dodero, Frank ^a,b   De La Maisonneuve, Caroline ^a,b   Lambert, Renée ^a,b   Brisse, Joëlle ^a,b   Chamlian, Albert ^a,b  

^a AIX MARSEILLE UNIVERSITY   (France)

^b INSERM   (France)

Author keywords

Cholestasis; Cyclosporine A; Dietary lipids; Na+,K+ ATPase; Quantitative immunocytochemistry; Rat hepatocyte

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BILE SALT; CYCLOSPORIN A; PHOSPHATIDYLCHOLINE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE FLOW; CHOLESTASIS; CONTROLLED STUDY; FAT INTAKE; IMMUNOCYTOCHEMISTRY; INTRAPERITONEAL DRUG ADMINISTRATION; LASER MICROSCOPY; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BILE; BILE ACIDS AND SALTS; CYCLOSPORINE; DIET, FAT-RESTRICTED; DIETARY FATS; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; ISOENZYMES; LIVER; MALE; MICROSCOPY, CONFOCAL; NA(+)-K(+)-EXCHANGING ATPASE; PHOSPHATIDYLCHOLINES; RATS; RATS, WISTAR; TRIGLYCERIDES;

EID: 0032878264     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026683531461     Document Type: Article

References (38)

1. Moseley RH, Johnson TR, Morrissette JM: Inhibition of bile acid transport by cyclosporine A in rat liver plasma membrane vesicles. J Pharmacol Exp Ther 253:974-980, 1990
2. Böhme M, Müller M, Leier I, Jedlitschky G, Keppler D: Cholestasis caused by inhibition of the adenosine triphosphate-dependent bile salt transport in rat liver. Gastroenterology 107:255-265, 1994
3. Cadranel JF, Babany G, Opolon P, Erlinger S: Pharmacocinétique et effects hépatiques de la cyclosporine A. Gastroenterol Clin Biol 16:314-321, 1992
4. Cadranel JF, Dumont M, Mesa VA, Degott C, Touchard D, Erlinger S: Effect of chronic administration of cyclosporin A on hepatic uptake and biliary secretion of bromosulfophtalein in rat. Dig Dis Sci 36:221-224, 1991
5. Chan FKL, Shaffer EA: Cholestatic effects of cyclosporine in the rat. Transplantation 63:1574-1578, 1997
6. Ericzon BG, Eusufzai S, Söderdahl G, Duraj F, Einarsson K, Angelin B: Secretion and composition of bile after human liver transplantation. Transplantation 63:74-80, 1997
7. Azer SA, Stacey NIJ: Differential effects of cyclosporine A on the transport of bile acids by human hepatocytes. Biochem Pharmacol 46:813-819, 1993
8. Princen HMG, Meijer P, Wolthers BG, Vonk RJ, Kuipers F: Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis. Biochem J 275:501-505, 1991
9. Kadmon M, Klünemann C, Böhme M, Ishikawa T, Gorgas K, Otto G, Herfarth C, Keppler D: Inhibition by cyclosporin A of adenosine triphosphate-dependent transport from the hepatocyte into bile. Gastroenterology 104:1507-1514, 1993
10. Cadranel JF, Erlinger S, Desruenne M, Luciani J, Lunel F, Grippon P, Cabrol A, Opolon P: Chronic administration of cyclosporin A induces a decrease in hepatic excretory function in man. Dig Dis Sci 37:1473-1476, 1992
11. Galan AI, Fernandez E, Moran D, Munoz ME, Jimenez R: Cyclosporine A hepatotoxicity: Effect of prolonged treatment with cyclosporine on biliary lipid secretion in the rat. Clin Exp Pharmacol Physiol 22:260-265, 1995
12. Lora L, Mazzon E, Billington D, Milanesi C, Naccarato R, Martines D: Effects of cyclosporin A on paracellular and transcellular transport of horseradish peroxidase in perfused rat livers. Dig Dis Sci 42:514-521, 1997
13. Roman ID, Coleman R: Disruption of canalicular function in isolated rat hepatocyte couplets caused by cyclosporin A. Biochem Pharmacol 48:2181-2188, 1994
14. Burwen SJ, Schmucker DL, Jones AL: Subcellular and molecular mechanisms of bile secretion. Int Rev Cytol 135:269-313, 1992
15. Yamazaki M, Suzuki H, Hanano M, Sugiyama Y: Different relationships between cellular ATP and hepatic uptake among taurocholate, cholate, and organic anions. Am J Physiol 264:G693-G701, 1993
16. +)-ATPase: A current view of its structure, function and localization in rat liver as revealed by studies with monoclonal antibodies. Hepatology 5:501-507, 1985
17. +-ATPase activity depends on membrane lipid fluidity. Proc Natl Acad Sci USA 85:8673-8677, 1988
18. +-ATPase from a "purified" light density "canalicular"-enriched plasma membrane fraction from rat liver. Hepatology 3:18-28, 1983
19. 1 subunit to the sinusoidal and lateral but not canalicular membranes of rat hepatocytes. J Cell Biol 104:1239-1248, 1987
20. Gatmaitan ZC, Arias IM: ATP-dependent transport systems in the canalicular membrane of the hepatocyte. Physiol Rev 75:261-269, 1995
21. +-ATP-A. Cell Mol Biol 34:215-222, 1988
22. 1 subunits in human and rat normal hepatocytes using confocal microscopy. Cell Mol Biol 41:499-504, 1905
23. Farthing MJG, Clark ML: Nature of the toxicity of cyclosporin A in the rat. Biochem Pharmacol 30:3311-3316, 1981
24. Polichetti E, Diaconescu N, Lechene de La Porte P, Malli L, Portugal H, Pauli AM, Lafont H, Tuchweber B, Yousef I, Chanussot F: Cholesterol-lowering effect of soyabean lecithin in normolipidaemic rats by stimulation of biliary lipid secretion, Br J Nutr 75:471-481, 1996
25. Polichetti E, Diaconescu N, Malli L, Lafont H, Tuchweber B, Yousef I, Chanussot F: Modèle non pharmacologique de l'inhibition de la sécrétion biliaire chez le rat, sous l'effet de l'acide déhydrocholique. Sci Tech An Lab 19:257-263, 1994
26. Domingo N, Amie J, Hauton J: Dosage automatique des sels biliaires de la bile par la 3α-hydroxystéroïde déshydrogénase. Clin Chim Acta 37:399-404, 1972
27. André P, Benoliel AM, Capo C, Foa C, Buferne M, Boyer C, Schmitt-Verhults AM, Bongrand P: Use of conjugates made between a cytolytic T cell clone and target cells to study the distribution of membrane molecules in cell contact areas. J Cell Sci 97:335-347, 1990
28. Benkoël L, Dodero F, Bongrand P, Benoliel AM, Lambert R, Brisse J, Sastre B, Cherid A, Chamlian A: Analysis by confocal laser scanning microscopy imaging of undilated bile canaliculi F-actin staining in the hepatocytes of human extrahepatic cholestatic liver. Cell Mol Biol 43:477-483, 1997
29. Roman ID, Monte MJ, Esteller A, Jimenez R: Cholestasis in the rat by means of intravenous administration of cyclosporine vehicle, Cremophor EL. Transplantation 48:554-558, 1989
30. +-ATPase activity by cyclosporin A. Kidney Int 43:246-251, 1993
31. Ferrer-Martinez A, Felipe A, Barcelo P, Casado FJ, Ballarin J, Pastor-Anglada M: Effects of cyclosporine A on Na,K-ATPase expression in the renal epithelial cell line NBL-1. Kidney Int 50:1483-1489, 1996
32. +-ATPase activities of canalicular-enriched rat liver plasma membranes. Gastroenterology 74:1183-1190, 1978
33. Whitington PF, Dudeja P, Hecht JR, Whitington SH, Brasitus TA: Lipid alterations in the hepatocyte basolateral sinusoidal membrane (BLM) domain may explain cyclosporine (CsA) induced cholestasis in the rat. Hepatology 8:1363, 1988
34. Clamp AG, Ladha S, Clark DC, Grimble RF, Lund EK: The influence of dietary lipids on the composition and membrane fluidity of rat hepatocyte plasma membrane. Lipids 32:179-184, 1997
35. Murphy MG: Dietary fatty acids and membrane protein function. J Nutr Biochem 1:68-79, 1990
36. Gerbi A, Barbey O, Raccah D, Coste T, Jamme I, Nouvelot A, Ouafik L, Lévy S, Vague P, Maixent JM: Alteration of Na,K-ATPase isoenzymes in diabetic cardiomyopathy: Effect of dietary supplementation with fish oil (n-3 fatty acids). Diabetologia 40:496-505, 1997
37. Chautan M, Chanussot F, Portugal H, Pauli AM, Lafont H: Effect of salmon oil on plasma lipid level and hepato-biliary cholesterol metabolism in rats. Biochem Biophys Acta 1046:40-45, 1990
38. +-dependent bile acid transport protein using monoclonal antibodies. J Cell Biol 263:11324-11330, 1987