Trophic effects of androgen: Development and hormonal regulation of neuron number in a sexually dimorphic vocal motor nucleus

Journal of Neurobiology

Volumn 40, Issue 3, 1999, Pages 375-385

  Kay, Jeremy N ^a   Hannigan, Patricia ^a   Kelley, Darcy B ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Androgen; Cell death; Motor neuron; Sexual differentiation; Xenopus

Indexed keywords

ANDROGEN; ANDROSTANOLONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DEATH; CELL SURVIVAL; FEMALE; HORMONAL REGULATION; HORMONE ACTION; HUMAN; LARVA; MALE; MOTONEURON NUCLEUS; NERVE CELL; NERVE FIBER GROWTH; NERVOUS SYSTEM DEVELOPMENT; PRIORITY JOURNAL; SEX DIFFERENCE; SEX DIFFERENTIATION; XENOPUS LAEVIS;

ANDROGENS; ANIMALS; APOPTOSIS; CELL COUNT; CELL MOVEMENT; CELL SURVIVAL; DIHYDROTESTOSTERONE; FEMALE; GLOSSOPHARYNGEAL NERVE; IN SITU NICK-END LABELING; MALE; MOTOR NEURONS; NEURONS; SEX CHARACTERISTICS; SEX DIFFERENTIATION; VAGUS NERVE; VOCALIZATION, ANIMAL; XENOPUS LAEVIS;

EID: 0032865580     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4695(19990905)40:3<375::AID-NEU9>3.0.CO;2-A     Document Type: Article

References (40)

1. Al-Shamma HA, Arnold AP. 1997. Brain-derived neurotrophic factor regulates expresson of androgen receptors in perineal motoneurons. Proc Natl Acad Sci USA 94:1521-1526.
2. Arai Y, Sekine Y, Murakama S. 1996. Estrogen and apoptosis in the developing sexually dimorphic preoptic area in female rats. Neurosci Res 25:403-407.
3. Arnold AP. 1992. Developmental plasticity in neural circuits controlling birdsong: sexual differentiation and the neural basis of learning. J Neurobiol 23:1506-1528.
4. Breedlove SM. 1992. Sexual dimorphism in the vertebrate nervous system. J Neurosci 12:4133-4142.
5. Burek MJ, Nordeen KW, Nordeen EJ. 1997. Sexually dimorphic neuron addition to an avian song-control region is not accounted for by sex differences in cell death. J Neurobiol 33:61-71.
6. Cohen MA, Kelley DB. 1996. Androgen-induced proliferation in the developing larynx of Xenopus laevis is regulated by thyroid hormone. Dev Biol 178:113-123.
7. Davis EC, Popper P, Gorski RA. 1996. The role of apoptosis in sexual differentiation of the rat sexually dimorphic nucleus of the preoptic area. Brain Res 734:10-18.
8. Dodd M, Dodd J. 1976. The biology of metamorphosis. In: Lofts B, editor. Physiology of the amphibia, Vol. III. New York: Academic Press. p 467-529.
9. Forger NG, Wagner CK, Contois M, Bengston L, Maclennan AJ. 1998. Ciliary neurotrophic factor receptor alpha in spinal motoneurons is regulated by gonadal hormones. J Neurosci 18:8720-8729.
10. Gorlick D, Kelley DB. 1987. Neurogenesis in vocalization pathway of Xenopus laevis. J Comp Neurol 257:614-627.
11. Jacobson MD, Weil M, Raff MC. 1997. Programmed cell death in animal development. Cell 88:347-354.
12. Jordan CL, Padgett B, Hershey J, Prins G, Arnold A. 1997. Ontogeny of androgen receptor immunoreactivity in lumbar motoneurons and in the sexually dimorphic levator ani muscle of male rats. J Comp Neurol 379:88-98.
13. Kelley DB. 1988. Sexually dimorphic behaviors. Annu Rev Neurosci 11:225-251.
14. Kelley DB. 1996. Sexual differentiation in Xenopus laevis. In: Tinsley R, Kobel H, editors. The biology of Xenopus. Oxford: Clarendon Press. p 143-176.
15. Kelley DB, Dennison J. 1990. The vocal notor neurons of Xenopus laevis: development of sex differences in axon number. J Neurobiol 21:869-882.
16. Kelley DB, Fenstemaker S, Hannigan P, Shin S. 1988. The sexually dimorphic laryngeal motor neurons of Xenopus laevis: a quantitative golgi study. J Neurobiol 19:413-429.
17. Kelley DB, Tobias ML. 1999. Vocal communication in Xenopus laevis. In: Hauser M, Konishi M, editors. Neural mechanisms of communication. Cambridge: MIT Press. p 9-35.
18. Kirn JR, Devoogd TJ. 1989. Genesis and death of vocal control neurons during sexual differentiation in the zebra finch. J Neurosci 9:3176-3187.
19. Konishi M, Akutagawa E. 1987. Hormonal control of cell death in a sexually dimorphic song nucleus in the zebra finch. Ciba Found Symp 126:173-185.
20. Hughes A. 1961. Cell degeneration in the larval ventral horn of Xenopus laevis (Daudin). J Embryol Exp Morphol 9:269-284.
21. Leloup J, Buscaglia M. 1977. Endocrinologie - La triiodothyroxine, hormone de la metamorphosis des amphibiens. C R Acad Sci Paris D 184:2261-2263.
22. Nieuwkoop PD, Faber J. 1956. Normal table of Xenopus laevis (Daudin). Amsterdam: Elsevier.
23. Nordeen E, Nordeen K, Sengelaub D, Arnold A. 1985. Androgens prevent normally occurring cell death in a sexually dimorphic spinal nucleus. Science 229:671-673.
24. Oppenheim RW. 1991. Cell death during development of the nervous system. Annu Rev Neurosci 14:453-501.
25. Perez J, Kelley DB. 1996. Trophic effects of androgen: receptor expression and survival of laryngeal motor neurons after axotomy. J Neurosci 16:6625-6633.
26. Perez J, Kelley DB. 1997. Androgen prevents axotomy-induced decreases in calbindin expression in motor neurons. J Neurosci 17:7396-7403.
27. Prestige MC. 1967. The control of cell number in the lumbar ventral horns during the development of Xenopus laevis tadpoles. J Embryol Exp Morphol 18:359-387.
28. Prestige MC, Wilson MA. 1972. Loss of axons from ventral nerve roots during development. Brain Res 41:467-470.
29. Robertson JC, Kelley DB. 1996. Thyroid hormone controls the onset of androgen sensitivity in the developing larynx of Xenopus laevis. Dev Biol 176:108-123.
30. Robertson JC, Watson JT, Kelley DB. 1994. Androgen directs sexual differentiation of laryngeal innervation in developing Xenopus laevis. J Neurobiol 25:1625-1636.
31. Sassoon D, Gray G, Kelley DB. 1987. Androgen regulation of muscle fiber type in the sexually dimorphic larynx of Xenopus laevis. J Neurosci 7:3198-3206.
32. Sassoon D, Kelley DB. 1986. The sexually dimorphic larynx of Xenopus laevis: development and androgen regulation. Am J Anat 177:457-472.
33. Sengelaub DR, Arnold AP. 1989. Hormonal control of neuron number in sexually dimorphic spinal nuclei of the rat: I. Testosterone-regulated death in the dorsolateral nucleus. J Comp Neurol 280:622-629.
34. Simpson HB, Tobias ML, Kelley DB. 1986. Origin and identification of fibers in the cranial nerve IX-X complex of Xenopus laevis: Lucifer yellow backfills in vitro. J Comp Neurol 244:430-444.
35. Tobias ML, Kelley DB. 1995. Sexual differentiation and endocrine regulation of the laryngeal synapse in Xenopus laevis. J Neurobiol 28:515-526.
36. Tobias ML, Kelley DB, Ellisman M. 1995. A sex difference in synaptic efficacy at the laryngeal neuromuscular junction of Xenopus laevis. J Neurosci 13:324-331.
37. Watson JT, Robertson J, Sachdev U, Kelley DB. 1993. Laryngeal muscle and motor neuron plasticity in Xenopus laevis: testicular masculinization of a developing neuromuscular system. J Neurobiol 24:1615-1625.
38. West MJ. 1993. New stereological methods for counting neurons. Neurobiol Aging 14:275-285.
39. Wetzel D, Kelley DB. 1983. Androgen and gonadotropin control the mate calls of male South African clawed frogs, Xenopus laevis. Horm Behav 17:388-404.
40. Xu J, Forger NG. 1998. Expression and androgen regulation of the ciliary neurotrophic factor receptor (CNTFRα) in muscles and spinal cord. J Neurobiol 35:217-225.