Androgen mitigates axotomy-induced decreases in calbindin expression in motor neurons

Journal of Neuroscience

Volumn 17, Issue 19, 1997, Pages 7396-7403

  Pérez, Julio ^a   Kelley, Darcy B ^a  

^a Howard Hughes Medical Institute   (United States)

Author keywords

Androgens; Calbindin; Calcium buffer; Dihydrotestosterone; Immunohistochemistry; Motor neuron death

Indexed keywords

ANDROGEN; CALBINDIN;

ANDROGEN RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; MALE; MOTONEURON; NERVE CELL NECROSIS; NERVE FIBER TRANSECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; XENOPUS LAEVIS;

EID: 1842297585     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-19-07396.1997     Document Type: Article

References (46)

1. Abercrombie M (1946) Estimation of nuclear population from microtome sections. Anat Rec 94: 239-247.
2. Baimbridge KG, Celio MR, Rogers JH (1992) Calcium-binding proteins in the nervous system. Trends Neurosci 15: 303-308.
3. Bao-Kuan H, Alexianu ME, Colom LV, Mohamed AH, Serrano F, Appel SH (1996) Expression of calbindin-D28k in motoneuron hybrid cells, after retroviral infection with calbindin-D28k cDNA prevents amyotrophic lateral sclerosis Ig-G-mediated cytotoxicity. Proc Natl Acad Sci USA 93: 6796-6801.
4. Barr ML, Hamilton JD (1948) A quantitative study of certain morphological changes in spinal motoneurons during axon reaction. J Comp Neurol 89: 93-121.
5. Beato M, Herrlich P, Schütz G (1995) Steroid hormone receptors: many actors in search of a plot. Cell 83: 851-857.
6. Berger FG, Watson G (1989) Androgen-regulated gene expression. Annu Rev Physiol 51: 51-65.
7. Blaustein M P (1988) Calcium transport and buffering in neurons. Trends Neurosci 11: 438-443.
8. Breedlove SM (1992) Sexual dimorphism in the vertebrate nervous system. J Neurosci 12: 4133-4142.
9. Chard PS, Jordan J, Marcuccilli CJ, Miller RJ, Leiden JM, Ross RP, J Ghadge GD (1995) Regulation of excitatory transmission at hippocampal synapse by calbindin-D28k. Proc Natl Acad Sci USA 92: 5144-5148.
10. Collazo D, Takahashi H, McKay RDG (1992) Cellular targets and trophic functions of neurotrophin-3 in the developing rat hippocampus. Neuron 9: 643-656.
11. Dutar P, Potier B, Lamour Y, Emson P, Senut M (1991) Loss of calbindin-28k immunoreactivity in hippocampal slices from aged rats; role for calcium? Eur J Neurosci 3: 839-849.
12. Ehlers MD, Zhang S, Bernhadt JP, Huganir RL (1996) Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit. Cell 84: 745-755.
13. García-Segura LM, Baetens D, Roth J, Norman AW, Orci L (1984) Immunohistochemical mapping of calcium-binding protein immunoreactivity in the rat central nervous system. Brain Res 296: 75-86
14. George EB, Glass JD, Griffin JW (1995) Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels. J Neurosci 15: 6445-6452.
15. Hauser KF, Torand-Allerand CD (1989) Androgen increases the number of cells in fetal mouse spinal cord cultures: implications for motoneuron survival. Brain Res 485: 157-164.
16. Ho BK, Alexianu ME, Colom LV, Mohamed AH, Serrano F, Appel SH (1996) Expression of calbindin-D28K in motoneuron hybrid cells after retroviral infection with calbindin-D28K cDNA prevents amyotrophic lateral sclerosis IgG-mediated cytotoxicity. Proc Natl Acad Sci USA 93: 6796-6801.
17. Iacopino AM, Christakos S (1990a) Corticosterone regulates calbindin-D28k mRNA and protein levels in rat hippocampus. J Biol Chem 265: 10177-10180.
18. Iacopino AM, Christakos S (1990b) Specific reduction of calcium-binding protein (28-kilodalton calbindin-D) gene expression in aging and neurodegenerative diseases. Proc Natl Acad Sci USA 87: 4078-4082.
19. Jande SS, Maler L, Lawson DEM (1981) Immunohistochemical mapping of vitamin D-dependent calcium-binding protein in brain. Nature 294: 765-767.
20. Jones KJ, Oblinger MM (1994) Androgenic regulation of tubulin gene expression in axotomized hamster facial motoneurons. J Neurosci 14: 3620-3627.
21. 3H-dihydrotestosterone. J Comp Neurol 199: 221-231.
22. Kelley DB, Morrell JI, Pfaff DW (1975) Autoradiographic localization of hormone-concentrating cells in the brain of an amphibian, Xenopus laevis, I. Testosterone. J Comp Neurol 164: 47-61.
23. Kop̈hr G, Mody I (1991) Endogenous intracellular calcium buffering and the activation/inactivation of HVA calcium currents in rat dentate gyrus granule cells. J Gen Physiol 98: 941-967.
24. Kujawa KA, Jones KJ (1995) Trophic actions of gonadal steroids on neuronal functioning normally and following injury. In: Advances in neuronal science, Vol 2, pp 131-152. JAI Press.
25. Kujawa KA, Emeric E, Jones KJ (1991) Testosterone differentially regulates the regenerative properties of injured hamster facial motoneurons. J Neurosci 11: 3898-3906.
26. Lieberman AR (1971) The axon reaction: a review of the principal features of perikaryal responses to injury. Int Rev Neurobiol 14: 49-124.
27. Marty S, Carroll P, Cellerino A, Castrén E, Staiger V, Thoenen H, Lindholm D (1996) Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures. J Neurosci 16: 675-687.
28. Mattson MP, Rychlik B, Chu C, Christakos S (1991) Evidence for calcium-reducing and excito-protective roles for the calcium-binding protein calbindin-D28k in cultured hippocampal neurons. Neuron 6: 41-51.
29. Mattson MP, Cheng B, Baldwin SA, Smith-Swintosky VL, Keller J, Geddes JW, Scheff KW, Christakos S (1995) Brain injury and tumor necrosis factors induce calbindin D-28k in astrocytes: evidence for cytoprotective response. J Neurosci Res 42: 357-370.
30. Munoz A, Muñoz M, González A, Donkelaar HJT (1995) Anuran dorsal column nucleus: organization, immunohistochemical characterization, and fiber connections in Rana perezi and Xenopus laevis. J Comp Neurol 363: 197-220.
31. Nordeen E, Nordeen K, Sengelaub D, Arnold A (1985) Androgens prevent normally occurring cell death in a sexually dimorphic spinal nucleus. Science 229: 671-673.
32. Pérez J, Kelley DB (1996) Trophic effects of androgens: receptor expression and the survival of laryngeal motoneurons after axotomy. J Neurosci 16: 6625-6633.
33. Pérez J, Cohen M, Kelley DB (1996) Androgen receptor mRNA expression in Xenopus laevis CNS; sexual dimorphism and regulation in the laryngeal motor nucleus. J Neurobiol 30: 556-568.
34. Peterson DA, Lucidi-Phillipi CA, Murphy DP, Ray J, Gage FH (1996) Fibroblast growth factor-2 protects entorhinal layer II glutamatergic neurons from axotomy-induced death. J Neurosci 16: 886-898.
35. Romagnolo B, Cluzeaud F, Lambert M, Colnot S, Porteau A, Molina T, Tomasset M, Vandewalle A, Kahn A, Perret C (1996) Tissue-specific and hormonal regulation of calbindin-D9k fusion genes in transgenic mice. J Biol Chem 271: 16820-16826.
36. 2+ homeostasis in rat sympathetic ganglion cells. Eur J Neurosci 6: 9-17.
37. Sanna PP, Celio MR, Bloom FE, Rende M (1993) Presumptive Renshaw cells contain decreased calbindin during recovery from sciatic nerve lesions. Proc Natl Acad Sci USA 90: 3048-3052.
38. Séquier JM, Hunziker W, Andressen C, Celio MR (1991) Calbindin D-28k protein and mRNA localization in the rat brain. Eur J Neurosci 2: 1118-1126.
39. Simpson HB, Tobias ML, Kelley DB (1986) Origin and identification of fibers in the cranial nerve IX-X complex of Xenopus laevis: Lucifer yellow backfills in vitro. J Comp Neurol 244: 430-444.
40. Sloviter RS (1989) Calcium-binding protein (Calbindin-D28k) and parvalbumin immunocytochemistry: localization in the rat hippocampus with specific reference to the selective vulnerability of hippocampal neurons to seizure activity. J Comp Neurol 280: 183-196.
41. Unemiya M, Araki I, Kuno M (1993) Electrophysiological properties of axotomized facial motoneurones that are destined to die in neonatal rats. J Physiol (Lond) 462: 661-678.
42. Ventimiglia R, Mather PE, Jones BE, Lindsay RM (1995) The neurotrophins BDNF, NT3, and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro. Eur J Neurosci 7: 213-222.
43. Wetzel D, Haerter U, Kelley D (1985) A proposed neural pathway for vocalization in South African clawed frogs, Xenopus laevis. J Comp Physiol 157: 749-761.
44. Winsky L, Kuznicki J (1996) Antibody recognition of calcium-binding proteins depends on their calcium-binding status. J Neurochem 66: 764-771.
45. Yu W-HA (1982) Effect of testosterone on the regeneration of hypoglossal nerve in rats. Exp Neurol 77: 129-141.
46. Yu W-HA (1989) Administration of testosterone attenuates neuronal loss following axotomy in the brainstem motor nuclei of female rats. J Neurosci 9: 3908-3914.