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Volumn 31, Issue 6, 1999, Pages 481-488

Structure and function of tight junctions. Role in intestinal barrier

Author keywords

Intestinal barrier; Intestinal permeability; Tight junction

Indexed keywords

BACTERIAL TOXIN; CALCIUM; CYTOKINE; DRUG; DRUG VEHICLE; GUANINE NUCLEOTIDE BINDING PROTEIN; HORMONE; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; PROTEIN; PROTEIN KINASE C; UNCLASSIFIED DRUG; ZONULA OCCLUDENS TOXIN;

EID: 0032862501     PISSN: 11258055     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (50)

References (83)
  • 2
    • 0025579702 scopus 로고
    • Pathobiology of the intestinal epithelial barrier
    • Madara JL. Pathobiology of the intestinal epithelial barrier. Am J Pathol 1990;137:1273-81.
    • (1990) Am J Pathol , vol.137 , pp. 1273-1281
    • Madara, J.L.1
  • 4
    • 0027441233 scopus 로고
    • Uptake and transport of macromolecules by the intestine: Possible role in clinical disorders (an update)
    • Sanderson IR, Walker WA. Uptake and transport of macromolecules by the intestine: possible role in clinical disorders (an update). Gastroenterology 1993;104:622-39.
    • (1993) Gastroenterology , vol.104 , pp. 622-639
    • Sanderson, I.R.1    Walker, W.A.2
  • 5
    • 0026572490 scopus 로고
    • The human intestinal unstirred layer: Evidence for extremely efficient luminal stirring
    • Levitt MD, Strocchi A, Levitt DG. The human intestinal unstirred layer: evidence for extremely efficient luminal stirring. Am J Physiol 1992;262:593-6.
    • (1992) Am J Physiol , vol.262 , pp. 593-596
    • Levitt, M.D.1    Strocchi, A.2    Levitt, D.G.3
  • 6
    • 0029935286 scopus 로고    scopus 로고
    • Role of the gut in multiple organ failure: Bacterial translocation and permeability changes
    • Swank GM, Deitch EA. Role of the gut in multiple organ failure: bacterial translocation and permeability changes. World J Surg 1996;20:411-7.
    • (1996) World J Surg , vol.20 , pp. 411-417
    • Swank, G.M.1    Deitch, E.A.2
  • 9
    • 0022550151 scopus 로고
    • The human intestinal microflora
    • Simon GL, Gorbach SL. The human intestinal microflora. Dig Dis Sci 1986;31(Suppl 1):147-62.
    • (1986) Dig Dis Sci , vol.31 , Issue.SUPPL. 1 , pp. 147-162
    • Simon, G.L.1    Gorbach, S.L.2
  • 11
    • 0015311097 scopus 로고
    • Ionic conductance of extracellular shunt pathway in rabbit ileum
    • Frizzell RA, Schultz SG. Ionic conductance of extracellular shunt pathway in rabbit ileum. J Gen Physiol 1972;59:318-46.
    • (1972) J Gen Physiol , vol.59 , pp. 318-346
    • Frizzell, R.A.1    Schultz, S.G.2
  • 12
    • 0019631483 scopus 로고
    • Barrier function of epithelia
    • Powell DW. Barrier function of epithelia. Am J Physiol 1981;241:G275-88.
    • (1981) Am J Physiol , vol.241
    • Powell, D.W.1
  • 14
    • 0023521841 scopus 로고
    • Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat
    • Pappenheimer JR, Reiss KZ. Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat. J Membr Biol 1987;100:123-36.
    • (1987) J Membr Biol , vol.100 , pp. 123-136
    • Pappenheimer, J.R.1    Reiss, K.Z.2
  • 17
    • 0022393433 scopus 로고
    • Occluding junction structure-function relationships in a cultured epithelial monolayer
    • Madara JL, Dharmsathaphorn K. Occluding junction structure-function relationships in a cultured epithelial monolayer. J Cell Biol 1985;101:2124-33.
    • (1985) J Cell Biol , vol.101 , pp. 2124-2133
    • Madara, J.L.1    Dharmsathaphorn, K.2
  • 18
    • 0016140812 scopus 로고
    • Structure and function of intercellular junctions
    • Staehelin LA. Structure and function of intercellular junctions. Int Rev Cytol 1974;39:191-283.
    • (1974) Int Rev Cytol , vol.39 , pp. 191-283
    • Staehelin, L.A.1
  • 19
    • 0024315423 scopus 로고
    • Morphogenesis of the polarized epithelial cell phenotype
    • Rodriguez-Boulan E, Nelson WJ. Morphogenesis of the polarized epithelial cell phenotype. Science 1989;245:718-25.
    • (1989) Science , vol.245 , pp. 718-725
    • Rodriguez-Boulan, E.1    Nelson, W.J.2
  • 20
    • 0023612699 scopus 로고
    • Structure, biochemistry and assembly of epithelial tight junction
    • Gumbiner B. Structure, biochemistry and assembly of epithelial tight junction. Am J Physiol 1987;253:C749-58.
    • (1987) Am J Physiol , vol.253
    • Gumbiner, B.1
  • 21
    • 0027715358 scopus 로고
    • Breaking through the tight junction barrier
    • Gumbiner B. Breaking through the tight junction barrier. J Cell Biol 1993;123:1631-3.
    • (1993) J Cell Biol , vol.123 , pp. 1631-1633
    • Gumbiner, B.1
  • 22
    • 0026345292 scopus 로고
    • Identification of a 160 kD polypeptide that binds to the tight junction protein ZO-1
    • Gumbiner B, Lowenkopf T, Apatira D. Identification of a 160 kD polypeptide that binds to the tight junction protein ZO-1. Proc Natl Acad Sci USA 1991;88:3460-4.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3460-3464
    • Gumbiner, B.1    Lowenkopf, T.2    Apatira, D.3
  • 23
    • 0017855840 scopus 로고
    • Morphological factors influencing transepithelial permeability: A model for the resistance of the zonula occludens
    • Claude P. Morphological factors influencing transepithelial permeability: a model for the resistance of the zonula occludens. J Membr Biol 1978;39:219-32.
    • (1978) J Membr Biol , vol.39 , pp. 219-232
    • Claude, P.1
  • 24
    • 0021251275 scopus 로고
    • Partitioning of paracellular conductance along the ileal crypt-villus axis: A hypothesis based on structural analysis with detailed consideration of tight junction-structure function relationships
    • Marcial MA, Carlson SL, Madara JL. Partitioning of paracellular conductance along the ileal crypt-villus axis: a hypothesis based on structural analysis with detailed consideration of tight junction-structure function relationships. J Membr Biol 1984;80:59-70.
    • (1984) J Membr Biol , vol.80 , pp. 59-70
    • Marcial, M.A.1    Carlson, S.L.2    Madara, J.L.3
  • 25
    • 0020061797 scopus 로고
    • Structure and permeability of goblet cell tight. junctions in rat small intestine
    • Madara JL, Trier JS. Structure and permeability of goblet cell tight. junctions in rat small intestine. J Membrane Biol 1982;66:145-57.
    • (1982) J Membrane Biol , vol.66 , pp. 145-157
    • Madara, J.L.1    Trier, J.S.2
  • 26
    • 0023176321 scopus 로고
    • Intestinal absorptive cell tight junctions are linked to cytoskeleton
    • Madara JL. Intestinal absorptive cell tight junctions are linked to cytoskeleton. Am J Physiol 1987;253:C171-5.
    • (1987) Am J Physiol , vol.253
    • Madara, J.L.1
  • 27
    • 0030669302 scopus 로고    scopus 로고
    • Physiological regulation of epithelial tight junction is associated with myosin light chain phosphorylation
    • 4Pt1
    • Turner JR, Rill BK, Carlson SL, Carnes D, Kerner R, Mrsny RJ, et al. Physiological regulation of epithelial tight junction is associated with myosin light chain phosphorylation. Am J Physiol 1997;273(4Pt1):C1378-85.
    • (1997) Am J Physiol , vol.273
    • Turner, J.R.1    Rill, B.K.2    Carlson, S.L.3    Carnes, D.4    Kerner, R.5    Mrsny, R.J.6
  • 28
    • 0023030826 scopus 로고
    • Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia
    • Stevenson BR, Siliciano JD, Mooseker MS, Goodenough DA. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol 1986;103:755-66.
    • (1986) J Cell Biol , vol.103 , pp. 755-766
    • Stevenson, B.R.1    Siliciano, J.D.2    Mooseker, M.S.3    Goodenough, D.A.4
  • 29
    • 0024789041 scopus 로고
    • The molecular constituents of intercellular junctions
    • Stevenson BR, Paul DL. The molecular constituents of intercellular junctions. Curr Opin Cell Biol 1989;1:884-91.
    • (1989) Curr Opin Cell Biol , vol.1 , pp. 884-891
    • Stevenson, B.R.1    Paul, D.L.2
  • 30
    • 0027414695 scopus 로고
    • Two classes of tight junctions are revealed by ZO-1 isoforms
    • Balda MS, Anderson JM. Two classes of tight junctions are revealed by ZO-1 isoforms. Am J Physiol 1993;264:C918-24.
    • (1993) Am J Physiol , vol.264
    • Balda, M.S.1    Anderson, J.M.2
  • 31
    • 0026603087 scopus 로고
    • Detection of the tight junction-associated protein ZO-1 in astrocytes and other nonepithelial cell type
    • Howarth AG, Hughes MR, Stevenson BR. Detection of the tight junction-associated protein ZO-1 in astrocytes and other nonepithelial cell type. Am J Physiol 1992;262:C461-9.
    • (1992) Am J Physiol , vol.262
    • Howarth, A.G.1    Hughes, M.R.2    Stevenson, B.R.3
  • 32
    • 0025888954 scopus 로고
    • A 220-kD undercoat-constitutive protein: Its specific localization at cadherin-based cell-cell adhesion sites
    • Itoh M, Yonemura S, Nagafuchi A, Tsukita SA, Tsukita SH. A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites. J Cell Biol 1991;115:1449-62.
    • (1991) J Cell Biol , vol.115 , pp. 1449-1462
    • Itoh, M.1    Yonemura, S.2    Nagafuchi, A.3    Tsukita, S.A.4    Tsukita, S.H.5
  • 33
    • 0027300689 scopus 로고
    • The 220-kD protein colocalization with cadherins in non-epithelial cells is identical to ZO-1 a tight junction-associated protein in epithelial cells: CDNA cloning and immunoelectron microscopy
    • Itoh M, Nagafuchi A, Yonemura S, Kitani-Yasuda K, Tsukita SA, Tsukita SH. The 220-kD protein colocalization with cadherins in non-epithelial cells is identical to ZO-1 a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J Cell Biol 1993;121:491-502.
    • (1993) J Cell Biol , vol.121 , pp. 491-502
    • Itoh, M.1    Nagafuchi, A.2    Yonemura, S.3    Kitani-Yasuda, K.4    Tsukita, S.A.5    Tsukita, S.H.6
  • 34
    • 0028289263 scopus 로고
    • Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells
    • Stevenson BR, Begg DA. Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells. J Cell Sci 1994;107:367-75.
    • (1994) J Cell Sci , vol.107 , pp. 367-375
    • Stevenson, B.R.1    Begg, D.A.2
  • 35
    • 0026752739 scopus 로고
    • Structure, function and regulation of cellular tight junctions
    • Schneeberger EE, Lynch RD. Structure, function and regulation of cellular tight junctions. Am J Physiol 1992;262:L647-61.
    • (1992) Am J Physiol , vol.262
    • Schneeberger, E.E.1    Lynch, R.D.2
  • 36
    • 0030740177 scopus 로고    scopus 로고
    • Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines
    • 1 Pt2:H286-94.
    • Blum MS, Toninelli E, Anderson JM, Balda MS, Zhou J, O'Donnell L, et al. Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines. Am J Physiol 1997;273(1 Pt2):H286-94.
    • (1997) Am J Physiol , vol.273
    • Blum, M.S.1    Toninelli, E.2    Anderson, J.M.3    Balda, M.S.4    Zhou, J.5    O'Donnell, L.6
  • 37
  • 39
    • 0030751655 scopus 로고    scopus 로고
    • Occludin as a possible determinant of tight junction permeability in endothelial cells
    • Hirase T, Staddon JM, Saitou M, Ando-Akatsuka Y, Itoh M, Furuse M, et al. Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci 1997;110:1603-13.
    • (1997) J Cell Sci , vol.110 , pp. 1603-1613
    • Hirase, T.1    Staddon, J.M.2    Saitou, M.3    Ando-Akatsuka, Y.4    Itoh, M.5    Furuse, M.6
  • 41
    • 0029912970 scopus 로고    scopus 로고
    • Interspecies diversity of occludin sequence cDNA cloning of human, mouse, dog and rat-kangaroo omologues
    • Ando-Akatsuka Y, Saitou M, Hirase T, Kishi M, Sakakibara A, Itoh M, et al. Interspecies diversity of occludin sequence cDNA cloning of human, mouse, dog and rat-kangaroo omologues. J Cell Biol 1996;133:43-7.
    • (1996) J Cell Biol , vol.133 , pp. 43-47
    • Ando-Akatsuka, Y.1    Saitou, M.2    Hirase, T.3    Kishi, M.4    Sakakibara, A.5    Itoh, M.6
  • 42
    • 0030043414 scopus 로고    scopus 로고
    • Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilammellar bodies bearing tight junction-like structures
    • Furuse M, Fujimoto K, Sato N, Hirase T, Tsukita SA, Tsukita SH. Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilammellar bodies bearing tight junction-like structures. J Cell Sci 1996;109:429-35.
    • (1996) J Cell Sci , vol.109 , pp. 429-435
    • Furuse, M.1    Fujimoto, K.2    Sato, N.3    Hirase, T.4    Tsukita, S.A.5    Tsukita, S.H.6
  • 43
    • 0028828220 scopus 로고
    • Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins
    • Fujimoto K. Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes. J Cell Sci 1995;108:3443-9.
    • (1995) Application to the Immunogold Labeling of Intercellular Junctional Complexes. J Cell Sci , vol.108 , pp. 3443-3449
    • Fujimoto, K.1
  • 46
    • 0027393734 scopus 로고
    • Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2
    • Zhong J, Saitoh T, Minase T, Sawada N, Enomoto K, Mori M. Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2. J Cell Biol 1993;120:477-83.
    • (1993) J Cell Biol , vol.120 , pp. 477-483
    • Zhong, J.1    Saitoh, T.2    Minase, T.3    Sawada, N.4    Enomoto, K.5    Mori, M.6
  • 47
    • 0028109285 scopus 로고
    • Localization of the 7H6 antigen at tight junction correlates with the paracellular barrier function of MDCK cells
    • Zhong J, Enomoto K, Isomura H, Sawada N, Minase T, Oyamada M, et al. Localization of the 7H6 antigen at tight junction correlates with the paracellular barrier function of MDCK cells. Exp Cell Res 1994;214:614-20.
    • (1994) Exp Cell Res , vol.214 , pp. 614-620
    • Zhong, J.1    Enomoto, K.2    Isomura, H.3    Sawada, N.4    Minase, T.5    Oyamada, M.6
  • 48
    • 0030724368 scopus 로고    scopus 로고
    • The ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells
    • Yamamoto T, Harada N, Kano K, Taya S, Canaani E, Matsuura Y, et al. The ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells. J Cell Biol 1997;139:785-95.
    • (1997) J Cell Biol , vol.139 , pp. 785-795
    • Yamamoto, T.1    Harada, N.2    Kano, K.3    Taya, S.4    Canaani, E.5    Matsuura, Y.6
  • 50
  • 52
    • 0028786658 scopus 로고
    • Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia
    • Nusrat A, Giry M, Turner JR, Colgan SP, Parkos CA, Carnes D, et al. Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia. Proc Natl Acad Sci USA, 1995;92:10629-33.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10629-10633
    • Nusrat, A.1    Giry, M.2    Turner, J.R.3    Colgan, S.P.4    Parkos, C.A.5    Carnes, D.6
  • 53
    • 0032514134 scopus 로고    scopus 로고
    • Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases
    • Jou TS, Schneeberger EE, Nelson WJ. Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases. J Cell Biol 1998;142:101-15.
    • (1998) J Cell Biol , vol.142 , pp. 101-115
    • Jou, T.S.1    Schneeberger, E.E.2    Nelson, W.J.3
  • 54
    • 0032489875 scopus 로고    scopus 로고
    • ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin
    • Haskins J, Gu L, Wittchen ES, Hibbard J, Stevenson BR. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J Cell Biol 1998;141(1):199-208.
    • (1998) J Cell Biol , vol.141 , Issue.1 , pp. 199-208
    • Haskins, J.1    Gu, L.2    Wittchen, E.S.3    Hibbard, J.4    Stevenson, B.R.5
  • 55
    • 0032577975 scopus 로고    scopus 로고
    • Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
    • Furuse M, Fujita K, Hiiragi T, Fujimoto K, Tsukita S. Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 1998;141:1539-50.
    • (1998) J Cell Biol , vol.141 , pp. 1539-1550
    • Furuse, M.1    Fujita, K.2    Hiiragi, T.3    Fujimoto, K.4    Tsukita, S.5
  • 56
    • 0031886504 scopus 로고    scopus 로고
    • Biogenesis of tight junctions: The C-termi-nal domain of occludin mediates basolateral targeting
    • Matter K, Balda MS. Biogenesis of tight junctions: the C-termi-nal domain of occludin mediates basolateral targeting. J Cell Sci 1998;111:511-9.
    • (1998) J Cell Sci , vol.111 , pp. 511-519
    • Matter, K.1    Balda, M.S.2
  • 57
    • 0030998325 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide reduced intestinal barrier function and altered localization of 7H6 antigen in IEC-6 rat intestinal crypt cells
    • Kimura H, Sawada N, Tobioka H, Isomura H, Kokai Y, Hirata K, et al. Bacterial lipopolysaccharide reduced intestinal barrier function and altered localization of 7H6 antigen in IEC-6 rat intestinal crypt cells. J Cell Physiol 1997;171:284-90.
    • (1997) J Cell Physiol , vol.171 , pp. 284-290
    • Kimura, H.1    Sawada, N.2    Tobioka, H.3    Isomura, H.4    Kokai, Y.5    Hirata, K.6
  • 58
    • 0030007493 scopus 로고    scopus 로고
    • Infection of T84 cells with enteropathogenic Escherichia coli alters barrier and transport functions
    • Philpott DJ, McKay DM, Sherman PM, Perdue MH. Infection of T84 cells with enteropathogenic Escherichia coli alters barrier and transport functions. Am J Physiol 1996;270(4 Pt 1):G634-45.
    • (1996) Am J Physiol , vol.270
    • Philpott, D.J.1    McKay, D.M.2    Sherman, P.M.3    Perdue, M.H.4
  • 59
    • 0029883798 scopus 로고    scopus 로고
    • Identification of isoforms of G proteins and PKC that colocalize with tight junction
    • Dodane V, Kachar B. Identification of isoforms of G proteins and PKC that colocalize with tight junction. J Membr Biol 1996;149:199-209.
    • (1996) J Membr Biol , vol.149 , pp. 199-209
    • Dodane, V.1    Kachar, B.2
  • 60
    • 0030982357 scopus 로고    scopus 로고
    • Possible involvement of phosphorylation of occludin in tight junction formation
    • Sakakibara A, Furuse M, Saitou M, Ando Akatsuka Y, Tsukita S. Possible involvement of phosphorylation of occludin in tight junction formation. J Cell Biol 1997;137:1393-401.
    • (1997) J Cell Biol , vol.137 , pp. 1393-1401
    • Sakakibara, A.1    Furuse, M.2    Saitou, M.3    Ando Akatsuka, Y.4    Tsukita, S.5
  • 61
    • 0023917890 scopus 로고
    • ML-9 inhibits the vascular contraction via the inhibition of myosin light chain phosphorylation
    • Ishikawa T, Chijiwa T, Hagiwara M, Mamiya S, Saitoh M, Hidaka H. ML-9 inhibits the vascular contraction via the inhibition of myosin light chain phosphorylation. Mol Pharmacol 1988;33:598-603.
    • (1988) Mol Pharmacol , vol.33 , pp. 598-603
    • Ishikawa, T.1    Chijiwa, T.2    Hagiwara, M.3    Mamiya, S.4    Saitoh, M.5    Hidaka, H.6
  • 62
    • 0029119895 scopus 로고
    • Myosin light chain kinase-regulated endothelial cell contraction: The relationship between isometric tension, actin polymerization, myosin phosphorylation
    • Goeckeler ZM, Wjsolmerski RB. Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, myosin phosphorylation. J Cell Biol 1995;130:613-27.
    • (1995) J Cell Biol , vol.130 , pp. 613-627
    • Goeckeler, Z.M.1    Wjsolmerski, R.B.2
  • 63
    • 0023618586 scopus 로고
    • IPS-dependent Ca2+ release in permeabilized hepatocytes of endotoxemic and septic rats
    • Spitzer JA, Deaciuc IV. IPS-dependent Ca2+ release in permeabilized hepatocytes of endotoxemic and septic rats. Am J Physiol 1987;253:E130-4.
    • (1987) Am J Physiol , vol.253
    • Spitzer, J.A.1    Deaciuc, I.V.2
  • 65
    • 0023945559 scopus 로고
    • 1 renal epithelia: Similarity to phorbol ester tumor promoters
    • 1 renal epithelia: similarity to phorbol ester tumor promoters. J Cell Physiol 1988;134:357-66.
    • (1988) J Cell Physiol , vol.134 , pp. 357-366
    • Mullin, J.M.1    McGinn, M.T.2
  • 66
    • 0028799226 scopus 로고
    • Tight junctions and the molecular basis for regulation of paracellular permeability
    • Anderson JM, Van Itallie CM. Tight junctions and the molecular basis for regulation of paracellular permeability. Am J Physiol 1995;269:G467-75.
    • (1995) Am J Physiol , vol.269
    • Anderson, J.M.1    Van Itallie, C.M.2
  • 68
    • 0030958528 scopus 로고    scopus 로고
    • Intestinal epithelial barrier dysfunction in Crohn's disease
    • Ma TY. Intestinal epithelial barrier dysfunction in Crohn's disease. Proc Soc Exp Biol Med 1997;214:318-27.
    • (1997) Proc Soc Exp Biol Med , vol.214 , pp. 318-327
    • Ma, T.Y.1
  • 70
    • 0020618323 scopus 로고
    • A freeze fracture study of Crohn's disease of the terminal ileum: Changes in epithelial tight junction organization
    • Marin ML, Greenstein AJ, Geller SA, Gordon RE, Afuses AH Jr. A freeze fracture study of Crohn's disease of the terminal ileum: Changes in epithelial tight junction organization. Am J Gastroenterol 1983;78:537-47.
    • (1983) Am J Gastroenterol , vol.78 , pp. 537-547
    • Marin, M.L.1    Greenstein, A.J.2    Geller, S.A.3    Gordon, R.E.4    Afuses Jr., A.H.5
  • 71
    • 0031944553 scopus 로고    scopus 로고
    • Epithelial tight junction structure in the jejunum of children with acute and treated celiac sprue
    • 4 Pt 1:435-41.
    • Schulzke JD, Bntzel CJ, Schulzke I, Riecken EO, Fromm M. Epithelial tight junction structure in the jejunum of children with acute and treated celiac sprue. Pediatr Res 1998;43(4 Pt 1):435-41.
    • (1998) Pediatr Res , vol.43
    • Schulzke, J.D.1    Bntzel, C.J.2    Schulzke, I.3    Riecken, E.O.4    Fromm, M.5
  • 73
    • 0024351792 scopus 로고
    • Oestradiol-17-glucuronide increases tight junctional permeability in rat liver
    • Kan KS, Monte MJ, Parslow RA, Coleman R. Oestradiol-17-glucuronide increases tight junctional permeability in rat liver. Biochem J 1989;261:297-300.
    • (1989) Biochem J , vol.261 , pp. 297-300
    • Kan, K.S.1    Monte, M.J.2    Parslow, R.A.3    Coleman, R.4
  • 74
    • 0025218790 scopus 로고
    • The effect of tumor necrosis factor on epithelial tight junction and transepithelial permeability
    • Mullin JM, Snock KW. The effect of tumor necrosis factor on epithelial tight junction and transepithelial permeability. Cancer Res 1990;50:2172-6.
    • (1990) Cancer Res , vol.50 , pp. 2172-2176
    • Mullin, J.M.1    Snock, K.W.2
  • 75
    • 0024553788 scopus 로고
    • Interferon gamma directly affects barrier function of cultured intestinal epithelial monolayers
    • Madara JR, Stafford J. Interferon gamma directly affects barrier function of cultured intestinal epithelial monolayers. J Clin Invest 1989;83:724-7.
    • (1989) J Clin Invest , vol.83 , pp. 724-727
    • Madara, J.R.1    Stafford, J.2
  • 77
    • 0030870253 scopus 로고    scopus 로고
    • Hepatocyte tight junctional permeability is increased in rat experimental colitis
    • Lora L, Mazzon E, Martines D, Fries W, Muraca M, Martin A, et al. Hepatocyte tight junctional permeability is increased in rat experimental colitis. Gastroenterology 1997;113:1347-54.
    • (1997) Gastroenterology , vol.113 , pp. 1347-1354
    • Lora, L.1    Mazzon, E.2    Martines, D.3    Fries, W.4    Muraca, M.5    Martin, A.6
  • 78
    • 0030457242 scopus 로고    scopus 로고
    • Histamine reduces ZO-1 tight junctional protein expression in cultured retinal microvascular endothelial cells
    • Gardner TW, Lesher T, Khin S, Vu C, Barber AJ, Brennan WA. Histamine reduces ZO-1 tight junctional protein expression in cultured retinal microvascular endothelial cells. Biochem J 1996;320:717-21.
    • (1996) Biochem J , vol.320 , pp. 717-721
    • Gardner, T.W.1    Lesher, T.2    Khin, S.3    Vu, C.4    Barber, A.J.5    Brennan, W.A.6
  • 80
    • 0025757105 scopus 로고
    • Elevation of intracellular free calcium levels in Hep-2 cells infected with enteropathogenic Escherichia coli
    • Baldwin TJ, Ward W, Aitken A, Knutton S, Williams PH. Elevation of intracellular free calcium levels in Hep-2 cells infected with enteropathogenic Escherichia coli. Infect Immun 1991;59:1599-604.
    • (1991) Infect Immun , vol.59 , pp. 1599-1604
    • Baldwin, T.J.1    Ward, W.2    Aitken, A.3    Knutton, S.4    Williams, P.H.5
  • 81
    • 0028333679 scopus 로고
    • Signal transduction in human epithelial cells infected with attaching and effacing Escherichia coli in vitro
    • Dytoc MT, Fedorko L, Sherman PM. Signal transduction in human epithelial cells infected with attaching and effacing Escherichia coli in vitro. Gastroenterology 1994;106:1150-61.
    • (1994) Gastroenterology , vol.106 , pp. 1150-1161
    • Dytoc, M.T.1    Fedorko, L.2    Sherman, P.M.3
  • 83
    • 0030938926 scopus 로고    scopus 로고
    • Modulation of intestinal tight junctions by zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model
    • Fasano A, Uzzau S. Modulation of intestinal tight junctions by zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model. J Clin Invest 1997;99(6):1158-64.
    • (1997) J Clin Invest , vol.99 , Issue.6 , pp. 1158-1164
    • Fasano, A.1    Uzzau, S.2


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