-
1
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
-
Nelson, D.R., Koymans, L., Kamataki, T., Stegeman, J.J., Feyereisen, R., Waxman, D.J., Waterman, M.R., Gotoh, O., Coon, M.J., Estabrook, R.W., Gunsalus, I.C., and Nebert, D.W. (1996) P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 6, 1-42
-
(1996)
Pharmacogenetics
, vol.6
, pp. 1-42
-
-
Nelson, D.R.1
Koymans, L.2
Kamataki, T.3
Stegeman, J.J.4
Feyereisen, R.5
Waxman, D.J.6
Waterman, M.R.7
Gotoh, O.8
Coon, M.J.9
Estabrook, R.W.10
Gunsalus, I.C.11
Nebert, D.W.12
-
2
-
-
0028997955
-
"It's the genes, stupid." Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism
-
Kroemer, H.K. and Eichelbaum, M. (1995) "It's the genes, stupid." Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism. Life Sci. 56, 2285-2298
-
(1995)
Life Sci.
, vol.56
, pp. 2285-2298
-
-
Kroemer, H.K.1
Eichelbaum, M.2
-
3
-
-
0023196288
-
Chromosomal assignment of human cytochrome P-450 (debrisoquine/ sparteine type) to chromosome 22
-
Eichelbaum, M., Baur, M.P., Dengler, H.J., Osikowska-Evers, B.O., Tieves, G., Zekorn, C., and Rittner, C. (1987) Chromosomal assignment of human cytochrome P-450 (debrisoquine/ sparteine type) to chromosome 22. Br. J. Clin. Pharmacol. 23, 455-458
-
(1987)
Br. J. Clin. Pharmacol.
, vol.23
, pp. 455-458
-
-
Eichelbaum, M.1
Baur, M.P.2
Dengler, H.J.3
Osikowska-Evers, B.O.4
Tieves, G.5
Zekorn, C.6
Rittner, C.7
-
4
-
-
8944256082
-
Nomenclature for human CYP2D6 alleles
-
Daly, A.K., Brockmoller, J., Broly, F., Eichelbaum, M., Evans, W.E., Gonzalez, F.J., Huang, J.D., Idle, J.R., Ingelman-Sundberg, M., Ishizaki, T., Jacqz-Aigrain, E., Meyer, U.A., Nebert, D.W., Steen, V.M., Wolf, C.R., and Zanger, U.M. (1996) Nomenclature for human CYP2D6 alleles. Pharmacogenetics 6, 193-201
-
(1996)
Pharmacogenetics
, vol.6
, pp. 193-201
-
-
Daly, A.K.1
Brockmoller, J.2
Broly, F.3
Eichelbaum, M.4
Evans, W.E.5
Gonzalez, F.J.6
Huang, J.D.7
Idle, J.R.8
Ingelman-Sundberg, M.9
Ishizaki, T.10
Jacqz-Aigrain, E.11
Meyer, U.A.12
Nebert, D.W.13
Steen, V.M.14
Wolf, C.R.15
Zanger, U.M.16
-
5
-
-
0025036544
-
Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes
-
Kagimoto, M., Heim, M., Kagimoto, K., Zeugin, T., and Meyer, U.A. (1990) Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes. J. Biol. Chem. 265, 17209-17214
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 17209-17214
-
-
Kagimoto, M.1
Heim, M.2
Kagimoto, K.3
Zeugin, T.4
Meyer, U.A.5
-
6
-
-
0028109283
-
A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine
-
Evert, B., Griese, E.U., and Eichelbaum, M. (1994) A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine. Naunyn-Schmiedeberg's Arch. Pharmacol. 350, 434-439
-
(1994)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.350
, pp. 434-439
-
-
Evert, B.1
Griese, E.U.2
Eichelbaum, M.3
-
7
-
-
0023854270
-
Characterization of the common genetic defect in humans deficient in debrisoquine metabolism
-
Gonzalez, F.J., Skoda, R.C., Kimura, S., Umeno, M., Zanger, U.M., Nebert, D.W., Gelboin, H.V., Hardwick, J.P., and Meyer, U.A. (1988) Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. Nature 331, 442-446
-
(1988)
Nature
, vol.331
, pp. 442-446
-
-
Gonzalez, F.J.1
Skoda, R.C.2
Kimura, S.3
Umeno, M.4
Zanger, U.M.5
Nebert, D.W.6
Gelboin, H.V.7
Hardwick, J.P.8
Meyer, U.A.9
-
8
-
-
0028832796
-
Evidence that aspartic acid 301 is a critical substrate-contact residue in the active site of cytochrome P450 2D6
-
Ellis, S.W., Hayhurst, G.P., Smith, G., Lightfoot, T., Wong, M.M., Simula, A.P., Ackland, M.J., Sternberg, M.J., Lennard, M.S., Tucker, G.T., and Wolf, C.R. (1995) Evidence that aspartic acid 301 is a critical substrate-contact residue in the active site of cytochrome P450 2D6. J. Biol. Chem. 270, 29055-29058
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29055-29058
-
-
Ellis, S.W.1
Hayhurst, G.P.2
Smith, G.3
Lightfoot, T.4
Wong, M.M.5
Simula, A.P.6
Ackland, M.J.7
Sternberg, M.J.8
Lennard, M.S.9
Tucker, G.T.10
Wolf, C.R.11
-
9
-
-
0029971798
-
Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat
-
Imaoka, S., Yamada, T., Hiroi, T., Hayashi, K., Sakaki, T., Yabusaki, Y., and Funae, Y. (1996) Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat. Biochem. Pharmacol. 51, 1041-1050
-
(1996)
Biochem. Pharmacol.
, vol.51
, pp. 1041-1050
-
-
Imaoka, S.1
Yamada, T.2
Hiroi, T.3
Hayashi, K.4
Sakaki, T.5
Yabusaki, Y.6
Funae, Y.7
-
10
-
-
0028977906
-
Expression of cytochrome P450 2D6 in Escherichia coli, purification, and spectral and catalytic characterization
-
Gillam, E.M., Guo, Z., Martin, M.V., Jenkins, C.M., and Guengerich, F.P. (1995) Expression of cytochrome P450 2D6 in Escherichia coli, purification, and spectral and catalytic characterization. Arch. Biochem. Biophys. 319, 540-550
-
(1995)
Arch. Biochem. Biophys.
, vol.319
, pp. 540-550
-
-
Gillam, E.M.1
Guo, Z.2
Martin, M.V.3
Jenkins, C.M.4
Guengerich, F.P.5
-
11
-
-
0029128324
-
Truncated human P450 2D6: Expression in Escherichia coli, Ni(2+)-chelate affinity purification, and characterization of solubility and aggregation
-
Kempf, A.C., Zanger, U.M., and Meyer, U.A. (1995) Truncated human P450 2D6: expression in Escherichia coli, Ni(2+)-chelate affinity purification, and characterization of solubility and aggregation. Arch. Biochem. Biophys. 321, 277-288
-
(1995)
Arch. Biochem. Biophys.
, vol.321
, pp. 277-288
-
-
Kempf, A.C.1
Zanger, U.M.2
Meyer, U.A.3
-
12
-
-
0030933378
-
Functional properties of Cyp2d6 1 (wild-type) and Cyp2d6 7 (His(324)Pro) expressed by recombinant baculovirus in insect cells
-
Evert, B., Eichelbaum, M., Haubruck, H., and Zanger, U.M. (1997) Functional properties of Cyp2d6 1 (wild-type) and Cyp2d6 7 (His(324)Pro) expressed by recombinant baculovirus in insect cells. Naunyn-Schmiedeberg's Arch. Pharmacol. 355, 309-318
-
(1997)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.355
, pp. 309-318
-
-
Evert, B.1
Eichelbaum, M.2
Haubruck, H.3
Zanger, U.M.4
-
13
-
-
0029986770
-
Functional high level expression of cytochrome P450 Cyp2d6 using baculoviral expression systems
-
Paine, M.J.I., Gilham, D., Roberts, G.C.K., and Wolf, C.R. (1996) Functional high level expression of cytochrome P450 Cyp2d6 using baculoviral expression systems. Arch. Biochem. Biophys. 328, 143-150
-
(1996)
Arch. Biochem. Biophys.
, vol.328
, pp. 143-150
-
-
Paine, M.J.I.1
Gilham, D.2
Roberts, G.C.K.3
Wolf, C.R.4
-
14
-
-
0029016682
-
Oxidative metabolism of bunitrolol by complementary DNA-expressed human cytochrome P450 isozymes in a human hepatoma cell line (Hep G2) using recombinant vaccinia virus
-
Ono, S., Tsutsui, M., Gonzalez, F.J., Satoh, T., Masubuchi, Y., Horie, T., Suzuki, T., and Narimatsu, S. (1995) Oxidative metabolism of bunitrolol by complementary DNA-expressed human cytochrome P450 isozymes in a human hepatoma cell line (Hep G2) using recombinant vaccinia virus. Pharmacogenetics 5, 97-102
-
(1995)
Pharmacogenetics
, vol.5
, pp. 97-102
-
-
Ono, S.1
Tsutsui, M.2
Gonzalez, F.J.3
Satoh, T.4
Masubuchi, Y.5
Horie, T.6
Suzuki, T.7
Narimatsu, S.8
-
15
-
-
0029018966
-
A new cytochrome P450 form belonging to the CYP2D in dog liver microsomes: Purification, cDNA cloning, and enzyme characterization
-
Sakamoto, K., Kirita, S., Baba, T., Nakamura, Y., Yamazoe, Y., Kato, R., Takanaka, A., and Matsubara, T. (1995) A new cytochrome P450 form belonging to the CYP2D in dog liver microsomes: purification, cDNA cloning, and enzyme characterization. Arch. Biochem. Biophys. 319, 372-382
-
(1995)
Arch. Biochem. Biophys.
, vol.319
, pp. 372-382
-
-
Sakamoto, K.1
Kirita, S.2
Baba, T.3
Nakamura, Y.4
Yamazoe, Y.5
Kato, R.6
Takanaka, A.7
Matsubara, T.8
-
16
-
-
0003609019
-
-
Oxford University Press, New York
-
O'Reilly, D.R., Miller, L.K., and Luckow, V.A. (1994) Baculovirus Expression Vectors: A Laboratory Manual, pp. 98-103, Oxford University Press, New York
-
(1994)
Baculovirus Expression Vectors: A Laboratory Manual
, pp. 98-103
-
-
O'Reilly, D.R.1
Miller, L.K.2
Luckow, V.A.3
-
17
-
-
0023476281
-
Oligonucleotide-directed construction of mutations via gapped duplex DNA in Methods
-
Wu, R. and Grossman, L., eds. Academic Press, San Diego
-
Kramer, W. and Fritz, H.J. (1987) Oligonucleotide-directed construction of mutations via gapped duplex DNA in Methods in Enzymology (Wu, R. and Grossman, L., eds.) Vol. 154, pp. 350-367, Academic Press, San Diego
-
(1987)
Enzymology
, vol.154
, pp. 350-367
-
-
Kramer, W.1
Fritz, H.J.2
-
18
-
-
78651165715
-
The carbon monoxide-binding pigment of liver microsomes: I. Evidence for its hemoprotein nature
-
Omura, T. and Sato, R. (1964) The carbon monoxide-binding pigment of liver microsomes: I. Evidence for its hemoprotein nature. J. Biol. Chem. 239, 2370-2378
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
19
-
-
0026639457
-
Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats
-
Suzuki, T., Narimatsu, S., Fujita, S., Masubuchi, Y., Umeda, S., Imaoka, S., and Funae, Y. (1992) Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats. Drug Metab. Dispos. 20, 367-373
-
(1992)
Drug Metab. Dispos.
, vol.20
, pp. 367-373
-
-
Suzuki, T.1
Narimatsu, S.2
Fujita, S.3
Masubuchi, Y.4
Umeda, S.5
Imaoka, S.6
Funae, Y.7
-
20
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
21
-
-
50449100139
-
The carbon monoxide-binding pigment of liver microsomes: II. Solubilization, purification, and properties
-
Omura, T. and Sato, R. (1964) The carbon monoxide-binding pigment of liver microsomes: II. Solubilization, purification, and properties. J. Biol. Chem. 239, 2379-2385
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2379-2385
-
-
Omura, T.1
Sato, R.2
-
22
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 680-685
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 680-685
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
23
-
-
0023256232
-
Purification of NADPH:cytochrome c (cytochrome P-450) reductase from hamster liver microsomes by detergent extraction and affinity chromatography
-
Ardies, C.M., Lasker, J.M., Bloswick, B.P., and Lieber, C.S. (1987) Purification of NADPH:cytochrome c (cytochrome P-450) reductase from hamster liver microsomes by detergent extraction and affinity chromatography. Anal. Biochem. 162, 39-46
-
(1987)
Anal. Biochem.
, vol.162
, pp. 39-46
-
-
Ardies, C.M.1
Lasker, J.M.2
Bloswick, B.P.3
Lieber, C.S.4
-
24
-
-
73849173955
-
Hepatic triphosphopyridine nucleotide-cytochrome c reductase: Isolation, characterization, and kinetic studies
-
Phillips, A.H. and Langdon, R.G. (1962) Hepatic triphosphopyridine nucleotide-cytochrome c reductase: isolation, characterization, and kinetic studies. J. Biol. Chem. 237, 2652-2660
-
(1962)
J. Biol. Chem.
, vol.237
, pp. 2652-2660
-
-
Phillips, A.H.1
Langdon, R.G.2
-
25
-
-
0000689283
-
Immunoblotting and immunodetection in Current Protocols
-
Ausubel, F.M., Brent, R., Kingston, R.B., Moore, D.D., Seidman, J.G., Smith, J.A., and Struhl, K., eds. Greene Publishing Associates and Wiley-Interscience, New York
-
Gallagher, S., Winston, S.E., Fuller, S.A., and Hurrell, J.G.R. (1992) Immunoblotting and immunodetection in Current Protocols in Molecular Biology (Ausubel, F.M., Brent, R., Kingston, R.B., Moore, D.D., Seidman, J.G., Smith, J.A., and Struhl, K., eds.) Vol. 1, pp. 10.18.11-10.18.16, Greene Publishing Associates and Wiley-Interscience, New York
-
(1992)
Molecular Biology
, vol.1
, pp. 101811-101816
-
-
Gallagher, S.1
Winston, S.E.2
Fuller, S.A.3
Hurrell, J.G.R.4
-
26
-
-
0028851873
-
Anti-peptide antibodies to the P4502D subfamily in rat, dog and man
-
Nakamura, A., Yamamoto, Y., Tasaki, T., Sugimoto, C., Masuda, M., Kazusaka, A., and Fujita, S. (1995) Anti-peptide antibodies to the P4502D subfamily in rat, dog and man. Xenobiotica 25, 1103-1109
-
(1995)
Xenobiotica
, vol.25
, pp. 1103-1109
-
-
Nakamura, A.1
Yamamoto, Y.2
Tasaki, T.3
Sugimoto, C.4
Masuda, M.5
Kazusaka, A.6
Fujita, S.7
-
27
-
-
0025701784
-
Image analysis for all
-
Lennard, P.R. (1990) Image analysis for all. Nature 347, 103-104
-
(1990)
Nature
, vol.347
, pp. 103-104
-
-
Lennard, P.R.1
-
28
-
-
0024416946
-
The CYP2D gene subfamily: Analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats
-
Matsunaga, E., Zanger, U.M., Hardwick, J.P., Gelboin, H.V., Meyer, U.A., and Gonzalez, F.J. (1989) The CYP2D gene subfamily: analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats. Biochemistry 28, 7349-7355
-
(1989)
Biochemistry
, vol.28
, pp. 7349-7355
-
-
Matsunaga, E.1
Zanger, U.M.2
Hardwick, J.P.3
Gelboin, H.V.4
Meyer, U.A.5
Gonzalez, F.J.6
-
29
-
-
0024520426
-
Gene family of male-specific testosterone 16 alpha-hydroxylase (C-P-450(16 alpha)) in mice. Organization, differential regulation, and chromosome localization
-
Wong, G., Itakura, T., Kawajiri, K., Skow, L., and Negishi, M. (1989) Gene family of male-specific testosterone 16 alpha-hydroxylase (C-P-450(16 alpha)) in mice. Organization, differential regulation, and chromosome localization. J. Biol. Chem. 264, 2920-2927
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 2920-2927
-
-
Wong, G.1
Itakura, T.2
Kawajiri, K.3
Skow, L.4
Negishi, M.5
-
30
-
-
0026671134
-
Characterization of the cytochrome P-450IID subfamily in bovine liver. Nucleotide sequences and microheterogeneity
-
Tsuneoka, Y., Matsuo, Y., Higuchi, R., and Ichikawa, Y. (1992) Characterization of the cytochrome P-450IID subfamily in bovine liver. Nucleotide sequences and microheterogeneity. Eur. J. Biochem. 208, 739-746
-
(1992)
Eur. J. Biochem.
, vol.208
, pp. 739-746
-
-
Tsuneoka, Y.1
Matsuo, Y.2
Higuchi, R.3
Ichikawa, Y.4
-
31
-
-
0029068435
-
Molecular cloning and sequencing of a guinea pig cytochrome P4502D (CYP2D16): High level expression in adrenal microsomes
-
Jiang, Q., Voigt, J.M., and Colby, H.D. (1995) Molecular cloning and sequencing of a guinea pig cytochrome P4502D (CYP2D16): high level expression in adrenal microsomes. Biochem. Biophys. Res. Commun. 209, 1149-1156
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.209
, pp. 1149-1156
-
-
Jiang, Q.1
Voigt, J.M.2
Colby, H.D.3
-
32
-
-
0031105836
-
Marmoset liver cytochrome P450s: Study for expression and molecular cloning of their cDNAs
-
Igarashi, T., Sakuma, T., Isogai, M., Nagata, R., and Kamataki, T. (1997) Marmoset liver cytochrome P450s: study for expression and molecular cloning of their cDNAs. Arch. Biochem. Biophys. 339, 85-91
-
(1997)
Arch. Biochem. Biophys.
, vol.339
, pp. 85-91
-
-
Igarashi, T.1
Sakuma, T.2
Isogai, M.3
Nagata, R.4
Kamataki, T.5
-
33
-
-
0028948688
-
5 on the stoichiometry of P450 2E1-catalyzed reactions
-
5 on the stoichiometry of P450 2E1-catalyzed reactions. Arch. Biochem. Biophys. 317, 504-513
-
(1995)
Arch. Biochem. Biophys.
, vol.317
, pp. 504-513
-
-
Patten, C.J.1
Koch, P.2
-
34
-
-
0029012009
-
CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4
-
Lee, C.A., Kadwell, S.H., Kost, T.A., and Serabjit-Singh, C.J. (1995) CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4. Arch. Biochem. Biophys. 319, 157-167
-
(1995)
Arch. Biochem. Biophys.
, vol.319
, pp. 157-167
-
-
Lee, C.A.1
Kadwell, S.H.2
Kost, T.A.3
Serabjit-Singh, C.J.4
-
35
-
-
0028129646
-
cDNA-directed expression of human cytochrome P450 CYP3A4 using baculovirus
-
Buters, J.T., Korzekwa, K.R., Kunze, K.L., Omata, Y., Hardwick, J.P., and Gonzalez, F.J. (1994) cDNA-directed expression of human cytochrome P450 CYP3A4 using baculovirus. Drug Metab. Dispos. 22, 688-692
-
(1994)
Drug Metab. Dispos.
, vol.22
, pp. 688-692
-
-
Buters, J.T.1
Korzekwa, K.R.2
Kunze, K.L.3
Omata, Y.4
Hardwick, J.P.5
Gonzalez, F.J.6
-
36
-
-
0029010216
-
cDNA-directed expression of human cytochrome P450 CYP1A1 using baculovirus. Purification, dependency on NADPH-P450 oxidoreductase, and reconstitution of catalytic properties without purification
-
Buters, J.T., Shou, M., Hardwick, J.P., Korzekwa, K.R., and Gonzalez, F.J. (1995) cDNA-directed expression of human cytochrome P450 CYP1A1 using baculovirus. Purification, dependency on NADPH-P450 oxidoreductase, and reconstitution of catalytic properties without purification. Drug Metab. Dispos. 23, 696-701
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 696-701
-
-
Buters, J.T.1
Shou, M.2
Hardwick, J.P.3
Korzekwa, K.R.4
Gonzalez, F.J.5
-
37
-
-
0028083213
-
Involvement of a cytochrome P4502D subfamily in human liver microsomal bunitrolol 4-hydroxylation
-
Narimatsu, S., Masubuchi, Y., Hosokawa, S., Ohmori, S., Kitada, M., and Suzuki, T. (1994) Involvement of a cytochrome P4502D subfamily in human liver microsomal bunitrolol 4-hydroxylation. Biol. Pharm. Bull. 17, 803-807
-
(1994)
Biol. Pharm. Bull.
, vol.17
, pp. 803-807
-
-
Narimatsu, S.1
Masubuchi, Y.2
Hosokawa, S.3
Ohmori, S.4
Kitada, M.5
Suzuki, T.6
-
38
-
-
0024418697
-
The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man
-
Kobayashi, S., Murray, S., Watson, D., Sesardic, D., Davies, D.S., and Boobis, A.R. (1989) The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man. Biochem. Pharmacol. 38, 2795-2799
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 2795-2799
-
-
Kobayashi, S.1
Murray, S.2
Watson, D.3
Sesardic, D.4
Davies, D.S.5
Boobis, A.R.6
-
39
-
-
0029050135
-
Potent inhibition of yeast-expressed CYP2D6 by dihydroquinidine, quinidine, and its metabolites
-
Ching, M.S., Blake, C.L., Ghabrial, H., Ellis, S.W., Lennard, M.S., Tucker, G.T., and Smallwood, R.A. (1995) Potent inhibition of yeast-expressed CYP2D6 by dihydroquinidine, quinidine, and its metabolites. Biochem. Pharmacol. 50, 833-837
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 833-837
-
-
Ching, M.S.1
Blake, C.L.2
Ghabrial, H.3
Ellis, S.W.4
Lennard, M.S.5
Tucker, G.T.6
Smallwood, R.A.7
-
40
-
-
0027230584
-
Major pathway of imipramine metabolism is catalyzed by cytochromes P-450 1A2 and P-450 3A4 in human liver
-
Lemoine, A., Gautier, J.C., Azoulay, D., Kiffel, L., Belloc, C., Guengerich, F.P., Maurel, P., Beaune, P., and Leroux, J.P. (1993) Major pathway of imipramine metabolism is catalyzed by cytochromes P-450 1A2 and P-450 3A4 in human liver. Mol. Pharmacol. 43, 827-832
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 827-832
-
-
Lemoine, A.1
Gautier, J.C.2
Azoulay, D.3
Kiffel, L.4
Belloc, C.5
Guengerich, F.P.6
Maurel, P.7
Beaune, P.8
Leroux, J.P.9
-
41
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada, T., Yamazaki, H., Mimura, M., Inui, Y., and Guengerich, F.P. (1994) Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 270, 414-423
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
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