-
1
-
-
0027300283
-
Nucleus basalis magnocellularis and hippocampus are the major sites of FMR1 expression in the brain
-
Abitbol M, Menini C, Delezoide AL, RhynerT, Vekemans M, Mallet J. 1993. Nucleus basalis magnocellularis and hippocampus are the major sites of FMR1 expression in the brain. Nature Genet 4:147-152.
-
(1993)
Nature Genet
, vol.4
, pp. 147-152
-
-
Abitbol, M.1
Menini, C.2
Delezoide, A.L.3
Rhyner, T.4
Vekemans, M.5
Mallet, J.6
-
2
-
-
0031445652
-
Analysis of domains affecting intracellular localization of the FMRP protein
-
Bardoni B, Sittler A, Shen Y, Mandel JL 1997. Analysis of domains affecting intracellular localization of the FMRP protein. Neurobiol Dis 4:329-336.
-
(1997)
Neurobiol Dis
, vol.4
, pp. 329-336
-
-
Bardoni, B.1
Sittler, A.2
Shen, Y.3
Mandel, J.L.4
-
3
-
-
0032546976
-
Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein
-
Brown V, Small K, Lakkis L, Feng Y, Gunter C, Wilkinson KD, Warren ST. 1998. Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein. J Biol Chem 273:15521-15527.
-
(1998)
J Biol Chem
, vol.273
, pp. 15521-15527
-
-
Brown, V.1
Small, K.2
Lakkis, L.3
Feng, Y.4
Gunter, C.5
Wilkinson, K.D.6
Warren, S.T.7
-
4
-
-
0030992812
-
The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo
-
Buckanovich RJ, Darnell RB. 1997. The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo. Mol Cell Biol 17:3194-3201.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3194-3201
-
-
Buckanovich, R.J.1
Darnell, R.B.2
-
5
-
-
0030760613
-
The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes
-
Corbin F, Bouillon M, Fortin A, Morin S, Rousseau F, Khandjian EW. 1997. The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes. Hum Mol Genet 6:1465-1472.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1465-1472
-
-
Corbin, F.1
Bouillon, M.2
Fortin, A.3
Morin, S.4
Rousseau, F.5
Khandjian, E.W.6
-
6
-
-
0003932766
-
-
New York: WH Freeman and Company
-
Creighton TE. 1993. Proteins. New York: WH Freeman and Company.
-
(1993)
Proteins
-
-
Creighton, T.E.1
-
7
-
-
0027509234
-
Point mutation in the FMR1 gene associated with fragile X mental retardation
-
De Boulle K, Ververk AJMH, Reyniers E, Vits L, Hendrickx J, Van Roy B, VanDenBos F, de Graaff E, Oostra BA, Willems PJA. 1993. Point mutation in the FMR1 gene associated with fragile X mental retardation. Nature Genet 3:31-35.
-
(1993)
Nature Genet
, vol.3
, pp. 31-35
-
-
De Boulle, K.1
Ververk, A.J.M.H.2
Reyniers, E.3
Vits, L.4
Hendrickx, J.5
Van Roy, B.6
VanDenBos, F.7
De Graaff, E.8
Oostra, B.A.9
Willems, P.J.A.10
-
8
-
-
0029858735
-
Characterization of the nucleic acid binding activity of KH domains: Different properties of different domains
-
Dejgaard K, Leffers H. 1996. Characterization of the nucleic acid binding activity of KH domains: Different properties of different domains. Eur J Biochem 241:425-431.
-
(1996)
Eur J Biochem
, vol.241
, pp. 425-431
-
-
Dejgaard, K.1
Leffers, H.2
-
9
-
-
0027176361
-
The FMR1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation
-
Devys D, Lutz Y, Rouyer N, Bellocq JP, Mandel JL. 1993. The FMR1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation. Nature Genet 4:335-340.
-
(1993)
Nature Genet
, vol.4
, pp. 335-340
-
-
Devys, D.1
Lutz, Y.2
Rouyer, N.3
Bellocq, J.P.4
Mandel, J.L.5
-
10
-
-
0029816723
-
The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals
-
Eberhart DE, Malter HE, Feng, Y, Warren ST. 1996. The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals. Hum Mol Genet 5:1083-1091.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1083-1091
-
-
Eberhart, D.E.1
Malter, H.E.2
Feng, Y.3
Warren, S.T.4
-
11
-
-
0025317922
-
MER1, a yeast gene required for chromosome pairing and genetic recombination, is induced in meiosis
-
Engebrecht J, Roeder GS. 1990. MER1, a yeast gene required for chromosome pairing and genetic recombination, is induced in meiosis. Mol Cell Biol 70:2379-2389.
-
(1990)
Mol Cell Biol
, vol.70
, pp. 2379-2389
-
-
Engebrecht, J.1
Roeder, G.S.2
-
12
-
-
0031310667
-
FMRP associates with polyribosomes as an mRNP, and the 1304N mutation of severe fragile X syndrome abolishes this association
-
Feng Y, Absher D, Eberhart DE, Brown V, Malter HE, Warren ST. 1997. FMRP associates with polyribosomes as an mRNP, and the 1304N mutation of severe fragile X syndrome abolishes this association. Mol Cell 1:109-118.
-
(1997)
Mol Cell
, vol.1
, pp. 109-118
-
-
Feng, Y.1
Absher, D.2
Eberhart, D.E.3
Brown, V.4
Malter, H.E.5
Warren, S.T.6
-
13
-
-
0029818460
-
A nuclear role for the fragile X mental retardation protein
-
Fridell RA, Benson RE, Hua J, Bogerd HP, Cullen BR. 1996. A nuclear role for the fragile X mental retardation protein. EMBO J 15:5408-5414.
-
(1996)
EMBO J
, vol.15
, pp. 5408-5414
-
-
Fridell, R.A.1
Benson, R.E.2
Hua, J.3
Bogerd, H.P.4
Cullen, B.R.5
-
14
-
-
0027258576
-
The KH domain occurs in a diverse set of RNA-binding proteins that include the antiterminator NusA and is probably involved in binding to nucleic acid
-
Gibson TJ, Thompson JD, Heringa J. 1993. The KH domain occurs in a diverse set of RNA-binding proteins that include the antiterminator NusA and is probably involved in binding to nucleic acid. FEBS Lett 3:361-366.
-
(1993)
FEBS Lett
, vol.3
, pp. 361-366
-
-
Gibson, T.J.1
Thompson, J.D.2
Heringa, J.3
-
15
-
-
0001966753
-
Physical and behavioral phenotype
-
Hagerman RJ, Silverman AC, eds. Baltimore, Maryland: Johns Hopkins University Press
-
Hagerman RJ. 1991. Physical and behavioral phenotype. In: Hagerman RJ, Silverman AC, eds. Fragile X syndrome: Diagnosis, treatment and research. Baltimore, Maryland: Johns Hopkins University Press, pp 3-88.
-
(1991)
Fragile X Syndrome: Diagnosis, Treatment and Research
, pp. 3-88
-
-
Hagerman, R.J.1
-
16
-
-
0001299954
-
FMR1 and mutations in fragile X syndrome: Molecular biology, biochemistry and genetics
-
Warren ST, Wells RD, eds. New York: Academic Press
-
Imbert G, Feng Y, Nelson DL, Warren ST, Mandel JL. 1998. FMR1 and mutations in fragile X syndrome: Molecular biology, biochemistry and genetics. In: Warren ST, Wells RD, eds. Genetic instabilities and hereditary neurological diseases. New York: Academic Press, pp 27-53.
-
(1998)
Genetic Instabilities and Hereditary Neurological Diseases
, pp. 27-53
-
-
Imbert, G.1
Feng, Y.2
Nelson, D.L.3
Warren, S.T.4
Mandel, J.L.5
-
17
-
-
0031862144
-
In vitro genetic analysis of the RNA binding site of vigilin, a multi-KH-domain protein
-
Kanamori H, Dodson RE, Shapiro DJ. 1998. In vitro genetic analysis of the RNA binding site of vigilin, a multi-KH-domain protein. Mol Cell Biol 18:3991-4003.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3991-4003
-
-
Kanamori, H.1
Dodson, R.E.2
Shapiro, D.J.3
-
18
-
-
0030059545
-
The fragile X mental retardation protein is associated with ribosomes
-
Kandjian E, Corbin F, Woerly S, Rousseau F. 1996. The fragile X mental retardation protein is associated with ribosomes. Nature Genet 12:91-93.
-
(1996)
Nature Genet
, vol.12
, pp. 91-93
-
-
Kandjian, E.1
Corbin, F.2
Woerly, S.3
Rousseau, F.4
-
19
-
-
0032007850
-
tRNA is entrapped in similar, but distinct, nuclear and cytoplasmic ribonuclear complexes, both of which contain vigilin and elongation factor 1α
-
Kruse C, Gruenweller A, Willkimm DK, Pfeiffer T, Hartmann RK, Mueller PK. 1998. tRNA is entrapped in similar, but distinct, nuclear and cytoplasmic ribonuclear complexes, both of which contain vigilin and elongation factor 1α. Biochem J 329:615-621.
-
(1998)
Biochem J
, vol.329
, pp. 615-621
-
-
Kruse, C.1
Gruenweller, A.2
Willkimm, D.K.3
Pfeiffer, T.4
Hartmann, R.K.5
Mueller, P.K.6
-
20
-
-
0343113370
-
Vigilin contains a functional nuclear localization sequence and is present in both cytoplasm and the nucleus
-
Kuegler S, Gruenweller A, Probst C, Klinger M, Mueller PK, Kruse C. (1996). Vigilin contains a functional nuclear localization sequence and is present in both cytoplasm and the nucleus. FEBS Lett 302:330-334.
-
(1996)
FEBS Lett
, vol.302
, pp. 330-334
-
-
Kuegler, S.1
Gruenweller, A.2
Probst, C.3
Klinger, M.4
Mueller, P.K.5
Kruse, C.6
-
21
-
-
0029076374
-
Characterization of two major cellular poly(rC)-binding human proteins each containing three K-homologous (KH) domains
-
Leffers H, Dejgaard K, Celis JE. 1995. Characterization of two major cellular poly(rC)-binding human proteins each containing three K-homologous (KH) domains. Eur J Biochem 230:447-453.
-
(1995)
Eur J Biochem
, vol.230
, pp. 447-453
-
-
Leffers, H.1
Dejgaard, K.2
Celis, J.E.3
-
22
-
-
0029775570
-
Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide
-
Macias MJ, Hyvonen M, Baraldi E, Schultz J, Sudol M, Saraste M, Oschkinat H. 1996. Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide. Nature 382:646-649.
-
(1996)
Nature
, vol.382
, pp. 646-649
-
-
Macias, M.J.1
Hyvonen, M.2
Baraldi, E.3
Schultz, J.4
Sudol, M.5
Saraste, M.6
Oschkinat, H.7
-
23
-
-
0026875908
-
Molecular genetics of the fragile X syndrome: A novel type of unstable mutation
-
Mandel JL, Heitz D. 1992. Molecular genetics of the fragile X syndrome: A novel type of unstable mutation. Curr Opin Gen Dev 2:422-430.
-
(1992)
Curr Opin Gen Dev
, vol.2
, pp. 422-430
-
-
Mandel, J.L.1
Heitz, D.2
-
24
-
-
0031031915
-
High resolution structure of ribosomal protein L11-C76, a helical protein with a flexible loop that becomes structured upon binding to RNA
-
Markus MA, Hinck AP, Huang S, Draper DE, Torchia DA. 1997. High resolution structure of ribosomal protein L11-C76, a helical protein with a flexible loop that becomes structured upon binding to RNA. Nature Struc Biol 4:70-76.
-
(1997)
Nature Struc Biol
, vol.4
, pp. 70-76
-
-
Markus, M.A.1
Hinck, A.P.2
Huang, S.3
Draper, D.E.4
Torchia, D.A.5
-
25
-
-
0031707505
-
Nucleocytoplasmic transport: The soluble phase
-
Mattaj IW, Englmeier L 1998. Nucleocytoplasmic transport: The soluble phase. Annu Rev Biochem 67:265-306.
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 265-306
-
-
Mattaj, I.W.1
Englmeier, L.2
-
26
-
-
0031230806
-
The solution structure of the first KH domain of FMR1, the protein responsible for fragile X syndrome
-
Musco G, Kharrat A, Stier S, Fraternali F, Gibson TJ, Nilges M, Pastore A. 1997. The solution structure of the first KH domain of FMR1, the protein responsible for fragile X syndrome. Nature Struc Biol 4:712-716.
-
(1997)
Nature Struc Biol
, vol.4
, pp. 712-716
-
-
Musco, G.1
Kharrat, A.2
Stier, S.3
Fraternali, F.4
Gibson, T.J.5
Nilges, M.6
Pastore, A.7
-
27
-
-
0029988528
-
Three-dimensional structure and stability of the KH domain: Molecular insights into the fragile X syndrome
-
Musco G, Stier G, Joseph C, Castiglione Morelli MA, Nilges M, Gibson TJ, Pastore A. 1996. Three-dimensional structure and stability of the KH domain: Molecular insights into the fragile X syndrome. Cell 85:237-245.
-
(1996)
Cell
, vol.85
, pp. 237-245
-
-
Musco, G.1
Stier, G.2
Joseph, C.3
Castiglione Morelli, M.A.4
Nilges, M.5
Gibson, T.J.6
Pastore, A.7
-
30
-
-
0025833298
-
Absence of expression of the FMR1 gene in fragile X syndrome
-
Pieretti M, Zhang F, Fu YH, Warren ST Oostra BA, Caskey CT, Nelson DL. 1991. Absence of expression of the FMR1 gene in fragile X syndrome. Cell 66:817-822.
-
(1991)
Cell
, vol.66
, pp. 817-822
-
-
Pieretti, M.1
Zhang, F.2
Fu, Y.H.3
Warren, S.T.4
Oostra, B.A.5
Caskey, C.T.6
Nelson, D.L.7
-
31
-
-
0028858599
-
Solution structure of a bovine immunodeficiency virus tat-TAR peptide-RNA complex
-
Puglisi JD, Chen L, Blanchard S, Frankel AD. 1995. Solution structure of a bovine immunodeficiency virus tat-TAR peptide-RNA complex. Science 270:1200-1203.
-
(1995)
Science
, vol.270
, pp. 1200-1203
-
-
Puglisi, J.D.1
Chen, L.2
Blanchard, S.3
Frankel, A.D.4
-
32
-
-
0027169638
-
Improved prediction of protein secondary structure by use of sequence profiles and neural networks
-
Rost B, Sander C. 1993. Improved prediction of protein secondary structure by use of sequence profiles and neural networks. Proc Natl Am Soc 90:7558-7562.
-
(1993)
Proc Natl Am Soc
, vol.90
, pp. 7558-7562
-
-
Rost, B.1
Sander, C.2
-
33
-
-
0028236525
-
Essential role for KH domains in RNA binding: Impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome
-
Siomi H, Choi MC, Siomi MC, Nussbaum RL, Dreyfuss G. 1994. Essential role for KH domains in RNA binding: Impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome. Cell 77:33-39.
-
(1994)
Cell
, vol.77
, pp. 33-39
-
-
Siomi, H.1
Choi, M.C.2
Siomi, M.C.3
Nussbaum, R.L.4
Dreyfuss, G.5
-
34
-
-
0027273728
-
The pre-mRNA binding K protein contains a novel evolutionary conserved motif
-
Siomi H, Matunis MJ, Michael WM, Dreyfuss G. 1993b. The pre-mRNA binding K protein contains a novel evolutionary conserved motif. Nucleic Acids Res 27:1193-1198.
-
(1993)
Nucleic Acids Res
, vol.27
, pp. 1193-1198
-
-
Siomi, H.1
Matunis, M.J.2
Michael, W.M.3
Dreyfuss, G.4
-
35
-
-
0027327486
-
The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein
-
Siomi H, Siomi MC, Choi MC, Nussbaum RL, Dreyfuss G. 1993a. The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein. Cell 74:1193-1198.
-
(1993)
Cell
, vol.74
, pp. 1193-1198
-
-
Siomi, H.1
Siomi, M.C.2
Choi, M.C.3
Nussbaum, R.L.4
Dreyfuss, G.5
-
36
-
-
0029069223
-
FXR1, an autosomal homolog of the fragile X mental retardation gene
-
Siomi MC, Siomi H, Sauer WH, Srinivisan S, Nussbaum RL, Dreyfuss G. 1995. FXR1, an autosomal homolog of the fragile X mental retardation gene. EMBO J 14:2401-2408.
-
(1995)
EMBO J
, vol.14
, pp. 2401-2408
-
-
Siomi, M.C.1
Siomi, H.2
Sauer, W.H.3
Srinivisan, S.4
Nussbaum, R.L.5
Dreyfuss, G.6
-
37
-
-
0029972935
-
Specific sequences in the fragile X syndrome protein FMR1 and FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them
-
Siomi MC, Zhang Y, Siomi H, Dreyfuss G. 1996. Specific sequences in the fragile X syndrome protein FMR1 and FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them. Mol Cell Biol 16:3825-3832.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3825-3832
-
-
Siomi, M.C.1
Zhang, Y.2
Siomi, H.3
Dreyfuss, G.4
-
38
-
-
0030051618
-
Alternative splicing of exon 14 determines nuclear or cytoplasmic localization of FMR1 protein isoforms
-
Sittler A, Devys D, Weber S, Mandel JL. 1996. Alternative splicing of exon 14 determines nuclear or cytoplasmic localization of FMR1 protein isoforms. Hum Mol Genet 5:95-102.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 95-102
-
-
Sittler, A.1
Devys, D.2
Weber, S.3
Mandel, J.L.4
-
39
-
-
0024009108
-
Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by RNA-binding specificities
-
Swanson MS, Dreyfuss G. 1988. Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by RNA-binding specificities. Mol Cell Biol 5:2237-2241.
-
(1988)
Mol Cell Biol
, vol.5
, pp. 2237-2241
-
-
Swanson, M.S.1
Dreyfuss, G.2
-
40
-
-
0031574072
-
The CLUSTALX windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
-
Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. 1997. The CLUSTALX windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25:4876-4882.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4876-4882
-
-
Thompson, J.D.1
Gibson, T.J.2
Plewniak, F.3
Jeanmougin, F.4
Higgins, D.G.5
-
41
-
-
0029087624
-
Protein-rRNA binding features and their structural and functional implications in ribosomes as determined by cross-linking studies
-
Urlaub H, Kruft V, Bischof O, Mueller EC, Wittmann-Liebold B. 1995. Protein-rRNA binding features and their structural and functional implications in ribosomes as determined by cross-linking studies. EMBO J 14:4578-4588.
-
(1995)
EMBO J
, vol.14
, pp. 4578-4588
-
-
Urlaub, H.1
Kruft, V.2
Bischof, O.3
Mueller, E.C.4
Wittmann-Liebold, B.5
-
42
-
-
0025905795
-
Identification of a gene (FMR1) containing a GCC repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
-
Verkerk AJMH, Pierretti M, Sutcliffe JS, Fu YH, Kuhl DPA, Pizzuti A, Reiner O, Richards S, Victoria MF, Zhang F, Eussen BE, van Ommen GJB, Blonden LAJ, Riggins GJ, Chastain JL, Kunst CB, Galijaard H, Caskey CT, Nelson DL, Oostra BA, Warren ST. 1991. Identification of a gene (FMR1) containing a GCC repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell 65:905-914.
-
(1991)
Cell
, vol.65
, pp. 905-914
-
-
Verkerk, A.J.M.H.1
Pierretti, M.2
Sutcliffe, J.S.3
Fu, Y.H.4
Kuhl, D.P.A.5
Pizzuti, A.6
Reiner, O.7
Richards, S.8
Victoria, M.F.9
Zhang, F.10
Eussen, B.E.11
Van Ommen, G.J.B.12
Blonden, L.A.J.13
Riggins, G.J.14
Chastain, J.L.15
Kunst, C.B.16
Galijaard, H.17
Caskey, C.T.18
Nelson, D.L.19
Oostra, B.A.20
Warren, S.T.21
more..
-
43
-
-
13144293035
-
The neuronal RNA-binding protein nova-2 is implicated as the autoantigen targeted in POMA patients with dementia
-
Yang YYL, Yin GL, Darnell RB. 1998. The neuronal RNA-binding protein nova-2 is implicated as the autoantigen targeted in POMA patients with dementia. Proc Natl Acad Sci USA 95:13254-13259. Cell 65:905-914.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13254-13259
-
-
Yang, Y.Y.L.1
Yin, G.L.2
Darnell, R.B.3
-
44
-
-
13144293035
-
-
Yang YYL, Yin GL, Darnell RB. 1998. The neuronal RNA-binding protein nova-2 is implicated as the autoantigen targeted in POMA patients with dementia. Proc Natl Acad Sci USA 95:13254-13259. Cell 65:905-914.
-
Cell
, vol.65
, pp. 905-914
-
-
|