Supraspinal and spinal delta2 opioid receptor-mediated antinociceptive synergy is mediated by spinal alpha2 adrenoceptors

Pain

Volumn 83, Issue 1, 1999, Pages 47-55

  Grabow, Theodore S ^a   Hurley, Robert W ^a   Banfor, Patricia N ^a   Hammond, Donna L ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

alpha2 Adrenoceptor; Antinociception; delta Opioid receptor; Isobologram; Rostral ventromedial medulla; Spinal cord

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DELTORPHIN[2 DEXTRO ALANINE 4 GLUTAMIC ACID]; DEXMEDETOMIDINE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; YOHIMBINE;

ADRENAL MEDULLA; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; INTRACEREBRAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; MALE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; TAIL FLICK TEST;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANALGESICS, OPIOID; ANESTHESIA, SPINAL; ANIMALS; DEXMEDETOMIDINE; DRUG SYNERGISM; INJECTIONS, SPINAL; MALE; NOCICEPTORS; NOREPINEPHRINE; OLIGOPEPTIDES; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, OPIOID, DELTA; SPINAL CORD; YOHIMBINE;

EID: 0032847514     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(99)00084-6     Document Type: Article

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