Mononuclear cells in corticosteroid-resistant asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 154, Issue 2 SUPPL., 1996, Pages

  Lane, Stephen J ^a   Lee, Tak H ^a  

^a GUY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PREDNISOLONE;

ASTHMA; DNA BINDING; DRUG BIOAVAILABILITY; DRUG RECEPTOR BINDING; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MONONUCLEAR CELL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RADIOASSAY; REVIEW;

EID: 0029737090     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm/154.2_pt_2.s49     Document Type: Review

References (17)

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2. Carmichael, J., I. C. Paterson, P. Diaz, G. K. Crompton, A. B. Kay, and I. W. B. Grant. 1981. Corticosteroid resistance in chronic asthma. B.M.J. 282:1419-1422.
3. Kay, A. B., P. Diaz, J. Carmichael, and I. W. B. Grant. 1981. Corticosteroid-resistant chronic asthma and monocyte complement receptors. Clin. Exp. Immunol. 44:576-580.
4. Poznansky, M. C., A. C. H. Gordon, J. G. Dolas, A. S. Krajewski, A. H. Wyllie, and I. W. B. Grant. 1984. Resistance to methylprednisolone in cultures of blood mononuclear cells from glucocorticoid-resistant asthmatic patients. Clin. Sci. 67:639-645.
5. Wyllie, A. H., M. C. Poznansky, and A. C. H. Gordon. 1986. Glucocorticoid resistant asthma: evidence for a defect in mononuclear cells. In A. B. Kay, editor. Asthma: Clinical Pharmacology and Therapeutic Progress. Blackwell Scientific Publications Inc., Boston. 304-306.
6. Lane, S. J., J. R. W. Wilkinson, G. M. Cochrane, T. H. Lee, and J. P. Arm. 1993. Differential in vitro regulation by glucocorticoids of monocyte-derived cytokine generation in glucocorticoid resistant bronchial asthma. Am. Rev. Respir. Dis. 147:690-696.
7. Lane, S. J., and T. H. Lee. 1991. Glucocorticoid receptor characteristics in monocytes of patients with corticosteriod-resistant bronchial asthma. Am. Rev. Respir. Dis. 143:1020-1024.
8. Wilkinson, J. R. W., S. J. Lane, and T. H. Lee. 1991. The effects of corticosteroids on cytokine generation and expression of activation antigens by monocytes in bronchial asthma. Int. Arch. Allergy Clin. Immunol. 94:220-221.
9. Corrigan, C. J., P. H. Brown, N. C. Barnes, J.-J. Tsai, A. J. Frew, and A. B. Kay. 1991. Peripheral blood T lymphocyte activation and comparison of the T lymphocyte inhibitory effects of glucocorticoids and cyclosporin A. Am. Rev. Respir. Dis. 144:1026-1032.
10. Leung, D. Y. M., R. M. Martin, S. J. Szefler, E. R. Sher, S. Ying, A. B. Kay, and Q. Hamid. 1995. Dysregulation of interleukin 4, interleukin 5, and interferon γ gene expression in steroid-resistant asthma. J. Exp. Med. 181:33-40.
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12. Corrigan, C. J., P. H. Brown, N. C. Barnes, S. J. Szefler, J.-J. Tsai, A. J. Frew, and A. B. Kay. 1991. Glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics, and inhibition of peripheral blood T cell proliferation by glucocorticoids in vitro. Am. Rev. Respir. Dis. 144:1016-1025.
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16. Lane, S. J., J. P. Arm, D. Z. Staynov, and T. H. Lee. 1994. Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma. Am. J. Respir. Cell Mol. Biol. 11:42-48.
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